hydroxyindoleacetic acid has been researched along with Alcohol Drinking in 55 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
Alcohol Drinking: Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Among treatment-seeking alcoholics, early age at onset is generally associated with a more severe course of alcoholism and lower cerebrospinal fluid 5-hydroxyindoleacetic acid concentration." | 3.69 | Early-onset alcoholics have lower cerebrospinal fluid 5-hydroxyindoleacetic acid levels than late-onset alcoholics. ( Brown, GL; Eckardt, MJ; Fils-Aime, ML; George, DT; Linnoila, M; Mefford, I, 1996) |
| " The effect of 10 g 5,7-dihydroxytryptamine (5,7-DHT) micro-injected into both the dorsal (DRN) and the median raphe nuclei (MRN) on the intake of ethanol in the low alcohol drinking (LAD) rat was measured using a standard 3-30% ethanol preference test." | 3.69 | Lesioning of midbrain raphe nuclei with 5,7-DHT fails to alter ethanol intake in the low alcohol drinking (LAD) rat. ( Adell, A; Myers, RD, 1996) |
| "Alcoholism is a complex disorder involving, among others, the serotoninergic (5-HT) system, mainly regulated by 5-HT(1A) autoreceptors in the dorsal raphe nucleus." | 1.35 | Chronic voluntary ethanol intake hypersensitizes 5-HT(1A) autoreceptors in C57BL/6J mice. ( Chouchana, L; Hamon, M; Hanoun, N; Kelaï, S; Lanfumey, L; Renoir, T; Saurini, F, 2008) |
| "5-Hydroxytryptophol glucuronide was measured by ELISA with good analytical precision, its diagnostic specificity and sensitivity was better than that of 5-hydroxytryptophol and its correlation was closer to ethyl glucuronide than to 5-hydroxytryptophol." | 1.34 | Determination of glucuronidated 5-hydroxytryptophol (GTOL), a marker of recent alcohol intake, by ELISA technique. ( Beck, O; Borg, S; Borucki, K; Dierkes, J; Weinmann, W; Wiesbeck, G; Wolfersdorf, M; Wurst, FM, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (20.00) | 18.7374 |
| 1990's | 24 (43.64) | 18.2507 |
| 2000's | 17 (30.91) | 29.6817 |
| 2010's | 3 (5.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kelaï, S | 1 |
| Renoir, T | 1 |
| Chouchana, L | 1 |
| Saurini, F | 1 |
| Hanoun, N | 1 |
| Hamon, M | 1 |
| Lanfumey, L | 1 |
| Wargelius, HL | 1 |
| Fahlke, C | 2 |
| Suomi, SJ | 3 |
| Oreland, L | 1 |
| Higley, JD | 4 |
| Eapen, DJ | 1 |
| Clements, S | 1 |
| Block, P | 1 |
| Sperling, L | 1 |
| Huggins, KN | 1 |
| Mathews, TA | 1 |
| Locke, JL | 1 |
| Szeliga, KT | 1 |
| Friedman, DP | 1 |
| Bennett, AJ | 1 |
| Jones, SR | 1 |
| Helander, A | 10 |
| Eriksson, CJ | 1 |
| Wurst, FM | 3 |
| Metzger, J | 1 |
| Stephanson, N | 2 |
| Dahl, H | 1 |
| Beck, O | 9 |
| Borucki, K | 2 |
| Schreiner, R | 1 |
| Dierkes, J | 2 |
| Jachau, K | 1 |
| Krause, D | 1 |
| Westphal, S | 1 |
| Luley, C | 1 |
| Schmidt-Gayk, H | 1 |
| Carlson, JN | 1 |
| Drew Stevens, K | 1 |
| Wolfersdorf, M | 1 |
| Weinmann, W | 1 |
| Wiesbeck, G | 1 |
| Borg, S | 4 |
| Oliveira-Silva, IF | 1 |
| Pinto, L | 1 |
| Pereira, SR | 1 |
| Ferraz, VP | 1 |
| Barbosa, AJ | 1 |
| Coelho, VA | 1 |
| Gualberto, FF | 1 |
| Souza, VF | 1 |
| Faleiro, RR | 1 |
| Franco, GC | 1 |
| Ribeiro, AM | 1 |
| Quintanilla, ME | 1 |
| Bustamante, D | 1 |
| Tampier, L | 1 |
| Israel, Y | 1 |
| Herrera-Marschitz, M | 1 |
| Jagota, A | 1 |
| Reddy, MY | 1 |
| Tekes, K | 1 |
| Zarcone, VP | 1 |
| Schreier, L | 1 |
| Mitchell, G | 1 |
| Orenberg, E | 1 |
| Barchas, J | 1 |
| Mena, MA | 1 |
| Herrera, E | 1 |
| Kiianmaa, K | 5 |
| Nurmi, M | 2 |
| Nykänen, I | 1 |
| Sinclair, JD | 3 |
| Jones, AW | 2 |
| Tipton, KF | 1 |
| Harrington, MC | 1 |
| Kennedy, NP | 1 |
| Adell, A | 3 |
| Myers, RD | 3 |
| Fils-Aime, ML | 1 |
| Eckardt, MJ | 1 |
| George, DT | 2 |
| Brown, GL | 1 |
| Mefford, I | 1 |
| Linnoila, M | 5 |
| Woods, JM | 1 |
| Druse, MJ | 1 |
| Panocka, I | 1 |
| Ciccocioppo, R | 1 |
| Polidori, C | 1 |
| Romagnoli, S | 1 |
| Froldi, R | 1 |
| Massi, M | 1 |
| Yoshimoto, K | 1 |
| Kaneda, S | 1 |
| Kawai, Y | 1 |
| Ueda, S | 1 |
| Takeuchi, Y | 1 |
| Matsushita, H | 1 |
| Yuri, K | 1 |
| Yasuhara, M | 1 |
| von Wachenfeldt, J | 1 |
| Hiltunen, A | 1 |
| Liljeberg, P | 1 |
| Vivian, JA | 1 |
| Woods, JH | 1 |
| Hansen, S | 1 |
| Hibbeln, JR | 1 |
| Umhau, JC | 1 |
| Shoaf, SE | 1 |
| Salem, N | 1 |
| Some, M | 1 |
| Rooke, N | 1 |
| Li, DJ | 1 |
| Li, J | 1 |
| Keung, WM | 2 |
| Kroke, A | 1 |
| Klipstein-Grobusch, K | 1 |
| Hoffmann, K | 1 |
| Terbeck, I | 1 |
| Boeing, H | 1 |
| Holman, RB | 1 |
| Hoyland, V | 1 |
| Shillito, EE | 1 |
| Wikström, T | 1 |
| Löwenmo, C | 1 |
| Jacobsson, G | 1 |
| Voltaire, A | 1 |
| Wahlström, G | 1 |
| Magnusson, O | 1 |
| Nordberg, A | 1 |
| Stenström, A | 1 |
| Tiger, G | 1 |
| Suzuki, T | 1 |
| Matsukawa, K | 1 |
| Misawa, M | 1 |
| Yanaura, S | 1 |
| Stenius, K | 1 |
| McBride, WJ | 3 |
| Murphy, JM | 3 |
| Gatto, GJ | 1 |
| Levy, AD | 1 |
| Lumeng, L | 3 |
| Li, TK | 3 |
| Aalto, J | 1 |
| Bosin, TR | 1 |
| Krogh, SE | 1 |
| Zabik, JE | 1 |
| Hilakivi, LA | 1 |
| Hilakivi, I | 1 |
| Ahtee, L | 2 |
| Eriksson, K | 2 |
| Geller, I | 1 |
| Purdy, R | 1 |
| Merritt, JH | 1 |
3 reviews available for hydroxyindoleacetic acid and Alcohol Drinking
| Article | Year |
|---|---|
Biochemical markers for the effects of ethanol.
Topics: Alcohol Drinking; Alcoholism; Aldehyde Dehydrogenase; Animals; Biomarkers; Ethanol; Genetic Markers; | 1993 |
The use of 5-hydroxytryptophol as an alcohol intake marker.
Topics: Alcohol Drinking; Alcoholism; Animals; Biomarkers; Chromatography, High Pressure Liquid; Ethanol; Ga | 1994 |
Determinants of alcohol preference in the AA and ANA rat lines selected for differential ethanol intake.
Topics: Alcohol Drinking; Animals; Behavior, Animal; Biogenic Amines; Brain; Ethanol; Food Preferences; Hydr | 1991 |
1 trial available for hydroxyindoleacetic acid and Alcohol Drinking
| Article | Year |
|---|---|
Detection of recent ethanol intake with new markers: comparison of fatty acid ethyl esters in serum and of ethyl glucuronide and the ratio of 5-hydroxytryptophol to 5-hydroxyindole acetic acid in urine.
Topics: Adult; Alcohol Drinking; Biomarkers; Esters; Fatty Acids; Female; Glucuronates; Humans; Hydroxyindol | 2005 |
51 other studies available for hydroxyindoleacetic acid and Alcohol Drinking
| Article | Year |
|---|---|
Chronic voluntary ethanol intake hypersensitizes 5-HT(1A) autoreceptors in C57BL/6J mice.
Topics: 5-Hydroxytryptophan; Action Potentials; Alcohol Drinking; Alcoholism; Animals; Behavior, Animal; Bod | 2008 |
Platelet monoamine oxidase activity predicts alcohol sensitivity and voluntary alcohol intake in rhesus monkeys.
Topics: Aggression; Alcohol Drinking; Alcoholism; Animals; Behavior, Animal; Ethanol; Female; Hydroxyindolea | 2010 |
Metastatic carcinoid disease inducing coronary vasospasm.
Topics: Aged; Alcohol Drinking; Antineoplastic Agents, Hormonal; Biomarkers; Carcinoid Heart Disease; Carcin | 2012 |
Effects of early life stress on drinking and serotonin system activity in rhesus macaques: 5-hydroxyindoleacetic acid in cerebrospinal fluid predicts brain tissue levels.
Topics: Alcohol Drinking; Analysis of Variance; Animals; Brain; Chromatography; Disease Models, Animal; Etha | 2012 |
Laboratory tests for acute alcohol consumption: results of the WHO/ISBRA Study on State and Trait Markers of Alcohol Use and Dependence.
Topics: Adolescent; Adult; Alcohol Drinking; Alcoholism; Biomarkers; Clinical Laboratory Techniques; Ethanol | 2002 |
The ethanol conjugate ethyl glucuronide is a useful marker of recent alcohol consumption.
Topics: Adolescent; Adult; Aged; Alcohol Drinking; Biomarkers; Female; Glucuronates; Humans; Hydroxyindoleac | 2002 |
Determination of urinary 5-hydroxytryptophol glucuronide by liquid chromatography-mass spectrometry.
Topics: 5-Hydroxytryptophan; Alcohol Drinking; Biomarkers; Chromatography, High Pressure Liquid; Glucuronide | 2005 |
Individual differences in ethanol self-administration following withdrawal are associated with asymmetric changes in dopamine and serotonin in the medial prefrontal cortex and amygdala.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Amygdala; Animals; Behavior, Animal; Central Nervo | 2006 |
Determination of glucuronidated 5-hydroxytryptophol (GTOL), a marker of recent alcohol intake, by ELISA technique.
Topics: Adult; Alcohol Drinking; Biomarkers; Enzyme-Linked Immunosorbent Assay; Glucuronides; Humans; Hydrox | 2007 |
Age-related deficit in behavioural extinction is counteracted by long-term ethanol consumption: correlation between 5-HIAA/5HT ratio in dorsal raphe nucleus and cognitive parameters.
Topics: Aging; Alcohol Drinking; Analysis of Variance; Animals; Behavior, Animal; Body Weight; Brain Chemist | 2007 |
Alcohol biomarker analysis: simultaneous determination of 5-hydroxytryptophol glucuronide and 5-hydroxyindoleacetic acid by direct injection of urine using ultra-performance liquid chromatography-tandem mass spectrometry.
Topics: Alcohol Drinking; Biomarkers; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrom | 2007 |
Dopamine release in the nucleus accumbens (shell) of two lines of rats selectively bred to prefer or avoid ethanol.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Alcoholism; Anesthesia, Inhalation; Animals; Breed | 2007 |
The effect of curcumin on ethanol induced changes in suprachiasmatic nucleus (SCN) and pineal.
Topics: Alcohol Drinking; Animals; Circadian Rhythm; Curcumin; Drug Evaluation, Preclinical; Ethanol; Hydrox | 2007 |
HPLC determination of serotonin and its metabolites from human platelet-rich plasma; shift to 5-hydroxytryptophol formation following alcohol consumption.
Topics: 5-Hydroxytryptophan; Adult; Alcohol Drinking; Chromatography, High Pressure Liquid; Female; Humans; | 2008 |
Sleep variables, cyclic AMP and biogenic amine metabolites after one day of ethanol ingestion.
Topics: Adult; Alcohol Drinking; Alcoholism; Cyclic AMP; Ethanol; Homovanillic Acid; Humans; Hydroxyindoleac | 1980 |
Monoamine metabolism in rat brain regions following long term alcohol treatment.
Topics: 5-Hydroxytryptophan; Alcohol Drinking; Alcoholism; Animals; Brain; Dihydroxyphenylalanine; Dopamine; | 1980 |
Effect of ethanol on extracellular dopamine in the nucleus accumbens of alcohol-preferring AA and alcohol-avoiding ANA rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Animals; Central Nervous System Depressants; Chrom | 1995 |
Distinguishing ingested ethanol from microbial formation by analysis of urinary 5-hydroxytryptophol and 5-hydroxyindoleacetic acid.
Topics: Adult; Alcohol Drinking; Alcoholic Intoxication; Candida albicans; Chromatography, High Pressure Liq | 1995 |
5-HT, dopamine, norepinephrine, and related metabolites in brain of low alcohol drinking (LAD) rats shift after chronic intra-hippocampal infusion of harman.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Animals; Brain; Chromatography, High Pressure Liqu | 1995 |
Laboratory testing for recent alcohol consumption: comparison of ethanol, methanol, and 5-hydroxytryptophol.
Topics: Adult; Alcohol Drinking; Alcoholism; Breath Tests; Ethanol; Female; Humans; Hydroxyindoleacetic Acid | 1996 |
Early-onset alcoholics have lower cerebrospinal fluid 5-hydroxyindoleacetic acid levels than late-onset alcoholics.
Topics: Adult; Age of Onset; Alcohol Drinking; Alcoholism; Comorbidity; Family; Female; Homovanillic Acid; H | 1996 |
Selective destruction of midbrain raphe nuclei by 5,7-DHT: is brain 5-HT involved in alcohol drinking in Sprague-Dawley rats?
Topics: 3,4-Dihydroxyphenylacetic Acid; 5,7-Dihydroxytryptamine; Alcohol Drinking; Animals; Brain Chemistry; | 1995 |
Lesioning of midbrain raphe nuclei with 5,7-DHT fails to alter ethanol intake in the low alcohol drinking (LAD) rat.
Topics: 5,7-Dihydroxytryptamine; Alcohol Drinking; Animals; Ethanol; Hydroxyindoleacetic Acid; Male; Mesence | 1996 |
Effects of chronic ethanol consumption and aging on dopamine, serotonin, and metabolites.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Alcohol Drinking; Animals; Brain; Dopamine; Hydroxyindoleacet | 1996 |
A nonhuman primate model of type II excessive alcohol consumption? Part 1. Low cerebrospinal fluid 5-hydroxyindoleacetic acid concentrations and diminished social competence correlate with excessive alcohol consumption.
Topics: Adult; Affect; Age Factors; Alcohol Drinking; Alcoholism; Animals; Arousal; Disease Models, Animal; | 1996 |
A nonhuman primate model of type II alcoholism? Part 2. Diminished social competence and excessive aggression correlates with low cerebrospinal fluid 5-hydroxyindoleacetic acid concentrations.
Topics: Adult; Age Factors; Aggression; Alcohol Drinking; Alcoholism; Animals; Antisocial Personality Disord | 1996 |
Possible mechanism of action for the attenuation of ethanol intake induced by ritanserin in rats.
Topics: 5,7-Dihydroxytryptamine; Alcohol Drinking; Animals; Brain; Ethanol; Hydroxyindoleacetic Acid; Inject | 1996 |
Genetically determined influences on voluntary ethanol consumption: extracellular levels of ethanol and monoamines in the nucleus accumbens of the alcohol preferring AA and alcohol avoiding ANA rat lines.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Animals; Biogenic Monoamines; Dopamine; Ethanol; E | 1994 |
Treating neonatal rats with 6-hydroxydopamine induced an increase in voluntary alcohol consumption.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Animals; Animals, Newborn; Biogenic Monoamines; Br | 1999 |
Comparison of urinary 5-hydroxytryptophol, breath ethanol, and self-report for detection of recent alcohol use during outpatient treatment: a study on methadone patients.
Topics: Alcohol Drinking; Biomarkers; Breath Tests; Female; Humans; Hydroxyindoleacetic Acid; Hydroxytryptop | 1999 |
Oral ethanol self-administration in rhesus monkeys: behavioral and neurochemical correlates.
Topics: Alcohol Drinking; Animals; Behavior, Addictive; Central Nervous System Depressants; Environment; Eth | 1999 |
Alcohol responsiveness, hyperreactivity, and motor restlessness in an animal model for attention-deficit hyperactivity disorder.
Topics: Alcohol Drinking; Animals; Attention Deficit Disorder with Hyperactivity; Brain Chemistry; Diazepam; | 1999 |
Plasma total cholesterol concentrations do not predict cerebrospinal fluid neurotransmitter metabolites: implications for the biophysical role of highly unsaturated fatty acids.
Topics: Adult; Age Factors; Alcohol Drinking; Cholesterol; Chromatography, High Pressure Liquid; Colorimetry | 2000 |
Dietary serotonin and alcohol combined may provoke adverse physiological symptoms due to 5-hydroxytryptophol.
Topics: Adult; Alcohol Drinking; Diarrhea; Diet; Drug Synergism; Ethanol; Fatigue; Female; Headache; Humans; | 2000 |
The mitochondrial monoamine oxidase-aldehyde dehydrogenase pathway: a potential site of action of daidzin.
Topics: Alcohol Deterrents; Alcohol Drinking; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; | 2000 |
Biogenic aldehyde(s) derived from the action of monoamine oxidase may mediate the antidipsotropic effect of daidzin.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Deterrents; Alcohol Drinking; Aldehyde Dehydrogenase; Aldehy | 2001 |
Comparison of self-reported alcohol intake with the urinary excretion of 5-hydroxytryptophol:5-hydroxyindole-3-acetic acid, a biomarker of recent alcohol intake.
Topics: 5-Hydroxytryptophan; Adult; Aged; Alcohol Drinking; Biomarkers; Female; Humans; Hydroxyindoleacetic | 2001 |
The failure of p-chlorophenylalanine to affect voluntary alcohol consumption in rats.
Topics: Alcohol Drinking; Animals; Brain Chemistry; Choice Behavior; Fenclonine; Hydroxyindoleacetic Acid; M | 1975 |
Urinary excretion of 5-hydroxyindole-3-acetic acid and 5-hydroxytryptophol after oral loading with serotonin.
Topics: Administration, Oral; Adult; Alcohol Drinking; Chromatography, High Pressure Liquid; Diet; Female; F | 1992 |
Urinary 5-hydroxytryptophol: a possible marker of recent alcohol consumption.
Topics: Adult; Alcohol Drinking; Alcoholic Intoxication; Dose-Response Relationship, Drug; Ethanol; Female; | 1992 |
Temporal studies of the inhibition of voluntary ethanol intake in the rat induced by intermittent ethanol treatment and some long term neurochemical consequences.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Alcoholism; Animals; Brain; Brain Mapping; Dopamin | 1991 |
Developmental changes in serotonergic neurons by maternal ethanol consumption in the rat offspring.
Topics: Age Factors; Alcohol Drinking; Animals; Brain; Female; Hydroxyindoleacetic Acid; Lactation; Pregnanc | 1991 |
Serotonin and dopamine systems regulating alcohol intake.
Topics: Alcohol Drinking; Alcoholism; Animals; Dopamine; Ethanol; Frontal Lobe; Hydroxyindoleacetic Acid; Li | 1991 |
Alcohol preference and regional brain monoamine contents of N/Nih heterogeneous stock rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Animals; Biogenic Amines; Brain Chemistry; Dopamin | 1987 |
Contents of monoamines in forebrain regions of alcohol-preferring (P) and -nonpreferring (NP) lines of rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Alcoholism; Animals; Biogenic Amines; Brain; Cereb | 1987 |
Role of brain monoaminergic systems in the increased ethanol drinking caused by REM-sleep deprivation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Animals; Brain Chemistry; Catecholamines; Citalopr | 1987 |
Tetrahydro-beta-carbolines in alcoholic beverages: quantitation, neurochemical and ethanol drinking effects.
Topics: 5-Hydroxytryptophan; Alcohol Drinking; Animals; Beer; Carbolines; Chemical Phenomena; Chemistry; Eth | 1987 |
Neonatal antidepressant administration suppresses concurrent active (REM) sleep and increases adult alcohol consumption in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Animals; Animals, Newborn; Brain Chemistry; Desipr | 1987 |
Regional distribution of brain 5-hydroxytryptamine in rat strains selected for their alcohol intake.
Topics: Alcohol Drinking; Alcoholism; Animals; Brain; Brain Chemistry; Disease Models, Animal; Ethanol; Huma | 1973 |
Alterations in ethanol preference in the rat: the role of brain biogenic amines.
Topics: 5-Hydroxytryptophan; Alcohol Drinking; Animals; Biogenic Amines; Brain Chemistry; Drinking Behavior; | 1973 |
5-Hydroxytryptamine and 5-hydroxyindolylacetic acid content in brain of rat strains selected for their alcohol intake.
Topics: Alcohol Drinking; Alcoholism; Animals; Body Temperature; Brain; Brain Chemistry; Disease Models, Ani | 1972 |