Page last updated: 2024-10-21

hydroxyindoleacetic acid and Aggression

hydroxyindoleacetic acid has been researched along with Aggression in 209 studies

(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.

Aggression: Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism.

Research Excerpts

ExcerptRelevanceReference
"Aggression is one of the symptoms of methamphetamine (MA) use and withdrawal, which can exacerbate MA addiction and relapse."7.91Melatonin pretreatment attenuates acute methamphetamine-induced aggression in male ICR mice. ( Chen, J; Li, S; Wang, X; Wang, Y; Wang, Z; Zhai, H, 2019)
"This study compared the nature and magnitude of the relationship between aggression and CSF 5-hydroxyindoleacetic acid (5-HIAA) concentration with that between aggression and the prolactin response to d-fenfluramine challenge in human subjects."7.69Central serotonin activity and aggression: inverse relationship with prolactin response to d-fenfluramine, but not CSF 5-HIAA concentration, in human subjects. ( Coccaro, EF; Cooper, TB; Hauger, RL; Kavoussi, RJ, 1997)
"The effects of fusaric acid (FA), a dopamine-beta-hydroxylase (D beta H) inhibitor, were determined on aggression, motor activity, and brain monoamines at doses of 3."7.66Effect of fusaric acid on aggression, motor activity, and brain monoamines in mice. ( Brown, JW; Diringer, MN; Kramarcy, NR; Thurmond, JB, 1982)
" Levels of CSF 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA), and 3-methoxy-4-hydroxyphenylglycol (MHPG), the metabolites of serotonin, dopamine, and norepinephrine, respectively, correlated significantly with behavioral measures of aggression and impulsivity/hyperactivity."5.07Cerebrospinal fluid monoamine metabolites in boys with attention-deficit hyperactivity disorder. ( Castellanos, FX; Elia, J; Gulotta, CS; Kruesi, MJ; Mefford, IN; Potter, WZ; Rapoport, JL; Ritchie, GF, 1994)
" So far, the attempts to correlate cerebrospinal fluid (CSF) 5-hydroxyindoleacetic acid (5-HIAA) levels with measures of aggression have revealed inverse, direct, or no correlations in different nonhuman primate species."4.77Brain 5-HT and inhibition of aggressive behavior in animals: 5-HIAA and receptor subtypes. ( Miczek, KA; Mos, J; Olivier, B, 1989)
" Our main results included the following: (1) The mortality and fin damage were higher and aggression was more intense of juvenile pufferfish at the 1% ration than those of the 3% ration; (2) during feeding, the velocity, body contact, and activity at the 1% ration were significantly higher than that of the 3% ration; (3) the concentrations of brain 5-hydroxyindoleacetic acid (5-HIAA) and monoamine oxidase A (MAOA) at the 1% ration were significantly lower, and dopamine (DA) concentrations were significantly higher."4.02Effects of food quantity on aggression and monoamine levels of juvenile pufferfish (Takifugu rubripes). ( Fan, J; Hu, Y; Li, H; Liu, Y; Ma, Z; Zhou, C, 2021)
"Aggression is one of the symptoms of methamphetamine (MA) use and withdrawal, which can exacerbate MA addiction and relapse."3.91Melatonin pretreatment attenuates acute methamphetamine-induced aggression in male ICR mice. ( Chen, J; Li, S; Wang, X; Wang, Y; Wang, Z; Zhai, H, 2019)
"Chronic gestational cocaine administration has been correlated with high levels of postpartum maternal aggression towards intruders and altered levels of oxytocin in the amygdala."3.72Effects of chronic cocaine on monoamine levels in discrete brain structures of lactating rat dams. ( Black, MC; Brown, LE; Cannon, JB; Johns, JM; Lubin, DA, 2003)
" Specifically, we examined relationships between handedness and cerebrospinal fluid (CSF) concentrations of the monoamine metabolites 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA), plasma concentrations of the hormones cortisol and adrenocorticotropin (ACTH), prolactin, and multiple indices of social behaviour, including proximity to other animals, grooming, submission, and aggression."3.72Biobehavioural correlates of hand preference in free-ranging female primates. ( Chavanne, TJ; Cleveland, A; Higley, JD; Houser, L; Snoy, PJ; Suomi, SJ; Westergaard, GC, 2004)
"The CSF AVP level was correlated directly with life history of general aggression and aggression against persons and inversely with PRL[d-FEN] responses (but not with CSF 5-hydroxyindoleacetic acid), which in turn was correlated inversely with these 2 measures of life history of aggression."3.70Cerebrospinal fluid vasopressin levels: correlates with aggression and serotonin function in personality-disordered subjects. ( Coccaro, EF; Cooper, TB; Ferris, CF; Hauger, RL; Kavoussi, RJ, 1998)
"CSF 5-hydroxyindoleacetic acid (5-HIAA) concentrations were inversely correlated with "escalated" aggression, i."3.69Low CSF 5-HIAA concentrations and severe aggression and impaired impulse control in nonhuman primates. ( Faucher, I; Higley, JD; Lilly, AA; Linnoila, M; Mehlman, PT; Suomi, SJ; Taub, DM; Vickers, J, 1994)
"Associations in 52 normal individuals were examined between plasma and cerebrospinal fluid (CSF) concentrations of tryptophan (Trp) and tyrosine, and concentrations of monoamine metabolites in the CSF, and scores on an aggression questionnaire, the Kinsey Institute Reaction List II, and the Eysenck Personality Questionnaire."3.69Aggression and personality: association with amino acids and monoamine metabolites. ( Alling, C; Bennicke, K; Breum, L; Bøge-Rasmussen, T; Jensen, C; Larsen, OG; Mortensen, EL; Møller, SE, 1996)
"This study compared the nature and magnitude of the relationship between aggression and CSF 5-hydroxyindoleacetic acid (5-HIAA) concentration with that between aggression and the prolactin response to d-fenfluramine challenge in human subjects."3.69Central serotonin activity and aggression: inverse relationship with prolactin response to d-fenfluramine, but not CSF 5-HIAA concentration, in human subjects. ( Coccaro, EF; Cooper, TB; Hauger, RL; Kavoussi, RJ, 1997)
" The 5-hydroxyindoleacetic acid concentration significantly predicted severity of physical aggression during follow-up."3.68A 2-year prospective follow-up study of children and adolescents with disruptive behavior disorders. Prediction by cerebrospinal fluid 5-hydroxyindoleacetic acid, homovanillic acid, and autonomic measures? ( Bartko, JJ; Hamburger, SD; Hibbs, ED; Keysor, CS; Kruesi, MJ; Rapoport, JL; Zahn, TP, 1992)
"Cerebrospinal fluid levels of 5-hydroxyindoleacetic acid, a metabolite of serotonin, were measured in relation to aggression, impulsivity, and social functioning in 29 children and adolescents with disruptive behavior disorders."3.68Cerebrospinal fluid monoamine metabolites, aggression, and impulsivity in disruptive behavior disorders of children and adolescents. ( Brown, GL; Hamburger, S; Hibbs, E; Kruesi, MJ; Lenane, M; Potter, WZ; Rapoport, JL, 1990)
" There were significant, negative correlations between interview-derived lifetime aggression scores and cerebrospinal fluid concentrations of both the serotonin metabolite 5-hydroxyindoleacetic acid and the dopamine metabolite homovanillic acid."3.68Personality and cerebrospinal fluid monoamine metabolites in alcoholics and controls. ( Adinoff, B; Goldman, D; Lamparski, D; Limson, R; Linnoila, M; Ravitz, B; Roy, A, 1991)
"Mice maintained on a basal casein diet supplemented with 4% L-tyrosine potentiated L-DOPA effects on aggression."3.67Effects of drug-induced changes in brain monoamines on aggression and motor behavior in mice. ( Brown, JW; Kramarcy, NR; Thurmond, JB, 1984)
"We review cerebrospinal fluid (CSF) studies suggesting on association between low CSF levels of the serotonin metabolite 5-hydroxyindoleacetic acid (5-HIAAA) and suicidal and impulsive behaviour and alcoholism."3.67Reduced central serotonin turnover in a subgroup of alcoholics? ( Linnoila, M; Roy, A; Virkkunen, M, 1987)
"The effects of fusaric acid (FA), a dopamine-beta-hydroxylase (D beta H) inhibitor, were determined on aggression, motor activity, and brain monoamines at doses of 3."3.66Effect of fusaric acid on aggression, motor activity, and brain monoamines in mice. ( Brown, JW; Diringer, MN; Kramarcy, NR; Thurmond, JB, 1982)
"In an earlier, separate study, the authors found that human aggression and suicide (a specific aggression-related behavior) were associated with lower levels of CSF 5-hydroxyindoleacetic acid (5-HIAA), a serotonin metabolite."3.66Aggression, suicide, and serotonin: relationships to CSF amine metabolites. ( Brown, GL; Bunney, WE; Ebert, MH; Goodwin, FK; Goyer, PF; Jimerson, DC; Klein, WJ, 1982)
"Definition, understanding, and treatment of antisocial personality disorder continue to present difficulties, but there have been several encouraging developments."2.37The antisocial personality: a review. ( Reid, WH, 1985)
"In fish, aggression has significant individual differences, and different personalities exhibit distinct behavioral performances and physiological stress responses."1.72Comparing behavioral performance and physiological responses of Sebastes schlegelii with different aggressiveness. ( Hu, Y; Li, H; Liu, Y; Ma, Z; Wang, J; Zhang, X, 2022)
"Depression and aggression in Alzheimer's disease (AD) are 2 of the most severe and prominent neuropsychiatric symptoms (NPS)."1.40Monoaminergic neurotransmitter alterations in postmortem brain regions of depressed and aggressive patients with Alzheimer's disease. ( Aerts, T; De Deyn, PP; Engelborghs, S; Van Dam, D; Vermeiren, Y, 2014)
"Older males and males with high-grade wounds were more likely to have anti-Seoul virus IgG and viral RNA in organs than either juveniles or adult males with less severe wounds."1.34Elevated testosterone and reduced 5-HIAA concentrations are associated with wounding and hantavirus infection in male Norway rats. ( Easterbrook, JD; Glass, GE; Kaplan, JB; Klein, SL; Pletnikov, MV, 2007)
"Fluoxetine-treated subjects (n = 6) had significantly lower Impulsivity Index scores than controls (n = 12)."1.31Social impulsivity inversely associated with CSF 5-HIAA and fluoxetine exposure in vervet monkeys. ( Fairbanks, LA; Jorgensen, MJ; Kaplan, JR; McGuire, MT; Melega, WP, 2001)
"Perpetrators with alcohol dependence (DV-ALC) (n=13), perpetrators without alcohol dependence (DV-NALC) (n=10) and healthy comparison subjects (HCS) (n=20) were clinically assessed using the Spielberger Trait Anxiety, Brown-Goodwin Aggression Scale, Buss Durkee Hostility Inventory and Straus Conflict Tactics."1.31Serotonin, testosterone and alcohol in the etiology of domestic violence. ( Emmela, D; George, DT; Phillips, MJ; Ragan, PW; Rawlings, RR; Shoaf, SE; Umhau, JC, 2001)
"Unlike apomorphine, Ro 15-1788 reversed catalepsy induced by haloperidol (0."1.27[Effect of an imidazobenzodiazepine (RO 15-1788) on aggressive behavior in mice]. ( Allikmets, LKh; Maĭmets, MO; Nurk, AM; Riago, LK; Vasar, EE, 1984)
"Studies have also linked alcohol abuse with aggression and criminality."1.27Serotonergic activity and disinhibitory psychopathy in alcoholism. ( Moss, HB, 1987)

Research

Studies (209)

TimeframeStudies, this research(%)All Research%
pre-1990100 (47.85)18.7374
1990's45 (21.53)18.2507
2000's36 (17.22)29.6817
2010's24 (11.48)24.3611
2020's4 (1.91)2.80

Authors

AuthorsStudies
Hu, Y2
Liu, Y2
Zhou, C1
Li, H2
Fan, J1
Ma, Z2
Wang, J1
Zhang, X1
Iba, H1
Watanabe, T1
Matsuzawa, K1
Saimiya, M1
Tanaka, M2
Nagao, M1
Moriyama, H1
Kubota, K1
Katsurabayashi, S1
Iwasaki, K1
Krupina, NA1
Khlebnikova, NN1
Narkevich, VB1
Naplekova, PL1
Kudrin, VS1
Sharma, R1
Tikka, SK1
Yadav, AK1
Bhute, AR1
Dhamija, P1
Bastia, BK1
Wang, FL1
Chassin, L1
Bates, JE1
Dick, D1
Lansford, JE1
Pettit, GS1
Dodge, KA1
Asellus, P1
Nordström, P4
Nordström, AL2
Jokinen, J3
Wang, Y1
Wang, X1
Chen, J1
Li, S1
Zhai, H1
Wang, Z1
Bubak, AN1
Swallow, JG1
Renner, KJ1
Kops, MS1
de Haas, EN1
Rodenburg, TB1
Ellen, ED1
Korte-Bouws, GA1
Olivier, B2
Güntürkün, O1
Bolhuis, JE1
Korte, SM2
Melotti, L1
Thomsen, LR1
Toscano, MJ1
Mendl, M1
Held, S1
Wolkers, CP2
Serra, M2
Szawka, RE1
Urbinati, EC2
Vermeiren, Y1
Van Dam, D1
Aerts, T1
Engelborghs, S1
De Deyn, PP1
Karpova, IV1
Mikheev, VV1
Marysheva, VV1
Bychkov, ER1
Proshin, SN1
Kulikov, AV2
Bazhenova, EY1
Kulikova, EA1
Fursenko, DV1
Trapezova, LI1
Terenina, EE1
Mormede, P2
Popova, NK3
Trapezov, OV1
Kubala, KH1
McGinnis, MY2
Anderson, GM3
Lumia, AR2
Chen, GL1
Novak, MA1
Meyer, JS1
Kelly, BJ1
Vallender, EJ1
Miller, GM1
Coccaro, EF4
Lee, R3
Wargelius, HL1
Fahlke, C1
Suomi, SJ15
Oreland, L1
Higley, JD18
Backström, T1
Pettersson, A1
Johansson, V1
Winberg, S3
Moberg, T1
Forslund, K1
Kristiansson, M1
Asberg, M4
Liu, C1
Cai, WX1
Wright, HF1
Mills, DS1
Pollux, PM1
Shen, YB1
Voilqué, G1
Kim, JD1
Odle, J1
Kim, SW1
Boparai, A1
Osipova, DV1
Naumenko, VS1
Terenina, E1
Martin, CB1
Ramond, F1
Farrington, DT1
Aguiar, AS1
Chevarin, C1
Berthiau, AS1
Caussanel, S1
Lanfumey, L1
Herrick-Davis, K1
Hamon, M1
Madjar, JJ1
Mongeau, R1
Duke, AA1
Bègue, L1
Bell, R1
Eisenlohr-Moul, T1
Franke, L1
Uebelhack, R1
Müller-Oerlinghausen, B1
Lubin, DA1
Cannon, JB1
Black, MC1
Brown, LE1
Johns, JM1
Westergaard, GC5
Chavanne, TJ3
Houser, L2
Hurley, A1
Cleveland, A5
Snoy, PJ3
Soderstrom, H1
Blennow, K1
Sjodin, AK1
Forsman, A1
Trenkle, MK2
Lussier, ID1
Prochazka, H1
Agren, H2
Birger, M1
Swartz, M1
Cohen, D1
Alesh, Y1
Grishpan, C1
Kotelr, M1
van der Vegt, BJ1
Lieuwes, N1
Cremers, TI1
de Boer, SF3
Koolhaas, JM2
Korzan, WJ1
Summers, CH2
van Hierden, YM1
Müller, JL1
Sommer, M1
Weber, T1
Hajak, G1
Maestripieri, D2
Lindell, SG3
Ayala, A1
Gold, PW1
Newman, TK1
McCormack, KM1
Sanchez, MM1
Koizumi, H1
Hashimoto, K1
Iyo, M1
Keleta, YB1
Howell, S1
Westergaard, G1
Hoos, B1
Shoaf, SE2
Dee Higley, J1
Easterbrook, JD1
Kaplan, JB1
Glass, GE1
Pletnikov, MV1
Klein, SL1
Homberg, JR1
Pattij, T1
Janssen, MC1
Ronken, E1
Schoffelmeer, AN1
Cuppen, E1
Mamiya, PC1
Hennesy, Z1
Zhou, R1
Wagner, GC2
Eleftheriou, BE1
Boehlke, KW1
Keverne, EB2
Eberhart, JA1
Yodyingyuad, U1
Abbott, DH1
Morez, VE1
Brown, GL7
Goodwin, FK8
Ballenger, JC2
Goyer, PF3
Valzelli, L10
Garattini, S6
Bernasconi, S3
Sala, A1
Kantak, KM2
Hegstrand, LR2
Eichelman, B3
Gibbons, JL3
Barr, GA4
Bridger, WH4
Leibowitz, SF3
Prasad, V1
Sheard, MH2
Diringer, MN1
Kramarcy, NR2
Brown, JW3
Thurmond, JB3
Dalessandro, M1
Ebert, MH1
Jimerson, DC1
Klein, WJ1
Bunney, WE2
Broderick, P1
Lynch, V1
Post, RM1
Ninan, PT1
van Kammen, DP1
Scheinin, M1
Linnoila, M19
Bertilsson, L2
Mårtensson, B1
Vasar, EE1
Maĭmets, MO1
Riago, LK1
Nurk, AM1
Allikmets, LKh2
Virkkunen, M9
George, T1
Higley, D1
Kallio, E1
Rawlings, R1
Tokola, R1
Poland, RE2
Guidotti, A1
Nemeroff, C1
Bissette, G1
Kalogeras, K1
Karonen, SL1
Reus, VI1
Van Praag, HM6
Ayuso Gutiérrez, JL1
Mehlman, PT7
Faucher, I2
Lilly, AA2
Taub, DM5
Vickers, J4
Castellanos, FX1
Elia, J1
Kruesi, MJ4
Gulotta, CS1
Mefford, IN1
Potter, WZ2
Ritchie, GF1
Rapoport, JL3
Bonson, KR1
Johnson, RG1
Fiorella, D1
Rabin, RA1
Winter, JC1
Rastegar, A1
Ciesielski, L2
Simler, S1
Messripour, M1
Mandel, P2
Davis, BA1
Durden, DA1
Pease, K1
Yu, PH1
Green, C1
Gordon, A1
Menzies, R1
Templeman, R1
Boulton, AA1
Fisher, H1
Pole, N1
Borve, T1
Johnson, SK1
Miachon, S1
Rochet, T1
Mathian, B1
Barbagli, B1
Claustrat, B1
Doudet, D1
Hommer, D2
Andreason, PJ1
Moneman, R1
Higley, SB2
Fernald, B1
Møller, SE1
Mortensen, EL1
Breum, L1
Alling, C1
Larsen, OG1
Bøge-Rasmussen, T1
Jensen, C1
Bennicke, K1
King, ST1
Hasert, MF1
Champoux, M1
Kraemer, GW1
Clarke, AS1
Fontenot, MB1
Kaplan, JR2
Shively, CA1
Manuck, SB1
Mann, JJ4
Reisner, IR1
Stanley, M2
Huang, YY2
Houpt, KA1
Conacher, GN1
Kavoussi, RJ2
Cooper, TB2
Hauger, RL2
Fernald, BJ1
Sallee, FR1
Summers, TR1
Hunter, AL1
Stanislav, SW1
Crismon, ML1
Childs, NL1
Heinz, A1
Gorey, JG1
Saunders, RC1
Jones, DW1
Zajicek, K1
Lesch, KP1
Weinberger, DR1
Ferris, CF1
van Goozen, SH1
Matthys, W1
Cohen-Kettenis, PT1
Westenberg, H1
van Engeland, H1
Chung, KK1
Martinez, M1
Herbert, J3
Stanley, B1
Molcho, A1
Winchel, R1
Gameroff, MJ1
Parsons, B1
Balaban, E1
Alper, JS1
Kasamon, YL1
Mitsis, EM1
Halperin, JM1
Newcorn, JH1
Woodley, SK1
Matt, KS1
Moore, MC1
Chiavegatto, S1
Dawson, VL1
Mamounas, LA1
Koliatsos, VE1
Dawson, TM1
Nelson, RJ1
Daly, RC1
Su, TP1
Schmidt, PJ1
Pickar, D2
Murphy, DL1
Rubinow, DR1
Devoino, LB1
Al'perina, EL1
Podgornaya, EK1
Polyakov, OV1
Idova, GV1
Il'yuchenok, RY1
Fairbanks, LA1
Melega, WP1
Jorgensen, MJ1
McGuire, MT2
Coccaro, E1
Avgustinovich, DF1
Lipina, TV1
Kudriavtseva, NN1
Brewerton, TD1
George, DT1
Umhau, JC1
Phillips, MJ1
Emmela, D1
Ragan, PW1
Rawlings, RR1
Placidi, GP1
Oquendo, MA1
Malone, KM1
Ellis, SP1
Øverli, Ø1
Lepage, O1
Pradhan, SN1
Marini, JL1
Kosten, T1
Major, LF1
Izquierdo, JA1
Rabiller, G1
Costas, SM1
Justel, EA1
Savini, CV1
Gradwell, PB1
Everitt, BJ1
Puca, FM2
Livrea, P2
Genco, S2
Specchio, LM2
Bandiera, L2
DiReda, L1
Takahashi, R1
Nishikawa, T1
Bioulac, B1
Benezech, M1
Renaud, B1
Roche, D1
Noël, B1
Daruna, JH1
Kent, EW1
Di Reda, L1
Zharkovskiĭ, AM1
Subrahmanyam, S1
Stern, WC1
Morgane, PJ1
Miller, M1
Resnick, O1
Bernard, BK3
Paolino, RM3
Neto, JP1
Nunes, JF1
Carvalho, FV1
Sakata, T1
Fuchimoto, H1
Kodama, J1
Fukushima, M1
Randt, CT1
Blizard, DA1
Friedman, E1
Greenberg, AS1
Coleman, M1
Nilsson, GE1
Olsén, KH1
Hibbs, ED1
Zahn, TP1
Keysor, CS1
Hamburger, SD1
Bartko, JJ1
Vickers, JH1
Linnoila, VM1
Linnoila, MI1
Hamburger, S1
Hibbs, E1
Lenane, M1
Leckman, JF1
Goodman, WK1
Riddle, MA1
Hardin, MT1
Limson, R1
Goldman, D1
Roy, A6
Lamparski, D1
Ravitz, B1
Adinoff, B1
Golden, RN1
Gilmore, JH1
Corrigan, MH1
Ekstrom, RD1
Knight, BT1
Garbutt, JC1
Nagatani, T1
Yamamoto, T1
Takao, K1
Hashimoto, S1
Kasahara, K1
Sugihara, T1
Ueki, S2
Mühlbauer, HD1
Reid, WH1
Payne, AP1
Andrews, MJ1
Wilson, CA1
López-Ibor, JJ1
Saiz-Ruiz, J1
Pérez de los Cobos, JC1
Puciłowski, O1
Kozak, W1
Vellucci, SV1
Guthrie, S1
Poland, R1
Sahakian, BJ1
Sarna, GS1
Kantamaneni, DB1
Jackson, A1
Hutson, PH1
Curzon, G1
Raleigh, MJ1
Brammer, GL1
Ritvo, ER1
Geller, E1
Yuwiler, A1
Kahn, R1
Asnis, GM1
Lemus, CZ1
Brown, SL1
Plutchik, R1
Conte, H1
Breier, A1
Doran, A1
Wolkowitz, O1
Colison, J1
Träskman-Bendz, L1
Depue, RA1
Spoont, MR1
Hong, KW1
Lee, WS1
Rhim, BY1
McMillen, BA1
Scott, SM1
Williams, HL1
Sanghera, MK1
Tani, Y1
Kataoka, Y1
Sakurai, Y1
Yamashita, K1
Ushio, M1
Molina, V1
Gobaille, S1
Isel, F1
Moss, HB1
Lee, EH1
Lin, HH1
Yin, HM1
Montgomery, SA1
Manev, H1
Pericić, D1
Mück-Seler, D1
Naumenko, EV1
Nikulina, EM1
Dygalo, NN1
Shishkina, GT1
Borodin, PM1
Markel, AL1
Ojesjö, L1
Miczek, KA1
Mos, J1
Young, SN1
Lidberg, L1
Tuck, JR1
Scalia-Tomba, GP1
Broderick, PA1
Sharpless, NS1
Goldberg, ME1
Insalaco, JR1
Hefner, MA1
Salama, AI1
Lycke, E2
Roos, BE2
Schrold, J1
Squires, RF1
Redmond, DE1
Maas, JW1
Kling, A1
Graham, CW1
Dekirmenjian, H1
Paroli, E1
Pantaleoni, GC1
Valeri, P1
Nencini, P1
Jame, R1
Vergnes, M2
Mack, G2
Kempf, E2
Giacalone, E2
Vogel, JR1
Haubrich, DR1
Modigh, K2
Kmieciak-Kolada, K1
Herman, ZS1
Slomińska-Zurek, J1
Welch, AS1
Welch, BL1
Tansella, M1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Pimavanserin on Aggression and Social Cognition.[NCT05895513]Phase 235 participants (Anticipated)Interventional2024-01-31Not yet recruiting
[NCT00004325]200 participants Observational1988-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

25 reviews available for hydroxyindoleacetic acid and Aggression

ArticleYear
Cerebrospinal fluid monoamine metabolite concentrations in suicide attempt: A meta-analysis.
    Asian journal of psychiatry, 2021, Volume: 62

    Topics: Aggression; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methoxyhydroxyphenylglycol; Suicide

2021
[Progress on relationship between omega-3 polyunsaturated fatty acids and violent-aggressive behavior].
    Fa yi xue za zhi, 2010, Volume: 26, Issue:6

    Topics: Aggression; Animals; Dietary Fats, Unsaturated; Dietary Supplements; Docosahexaenoic Acids; Eicosape

2010
Revisiting the serotonin-aggression relation in humans: a meta-analysis.
    Psychological bulletin, 2013, Volume: 139, Issue:5

    Topics: Adult; Aggression; Anger; Female; Hostility; Humans; Hydroxyindoleacetic Acid; Male; Serotonin; Sero

2013
Aggression: the testosterone-serotonin link.
    The Israel Medical Association journal : IMAJ, 2003, Volume: 5, Issue:9

    Topics: Aggression; Animals; Female; Fenfluramine; Humans; Hydroxyindoleacetic Acid; Macaca mulatta; Male; P

2003
Social influences on sex differences in the behavior and endocrine state of talapoin monkeys.
    Progress in brain research, 1984, Volume: 61

    Topics: Aggression; Animals; Behavior, Animal; Brain; Castration; Cercopithecidae; Endorphins; Estradiol; Fe

1984
The limbic system and aggression in humans.
    Neuroscience and biobehavioral reviews, 1983,Fall, Volume: 7, Issue:3

    Topics: Aggression; Amygdala; Anticonvulsants; Brain Diseases; Brain Mapping; Brain Neoplasms; Electroenceph

1983
CSF monoamine metabolites, depression, and suicide.
    Advances in biochemical psychopharmacology, 1984, Volume: 39

    Topics: Aggression; Analysis of Variance; Biogenic Amines; Depressive Disorder; Dexamethasone; Homicide; Hom

1984
Impulse control disorders.
    International clinical psychopharmacology, 1993, Volume: 8 Suppl 1

    Topics: Aggression; Alcoholism; Disruptive, Impulse Control, and Conduct Disorders; Frontal Lobe; Humans; Hy

1993
[Serotonergic function and aggressive-impulsive behavior].
    Acta psiquiatrica y psicologica de America latina, 1994, Volume: 40, Issue:1

    Topics: Adolescent; Adult; Aggression; Animals; Fluoxetine; Humans; Hydroxyindoleacetic Acid; Macaca mulatta

1994
Mean genes and the biology of aggression: a critical review of recent animal and human research.
    Journal of neurogenetics, 1996, Volume: 11, Issue:1-2

    Topics: Aggression; Animals; Disruptive, Impulse Control, and Conduct Disorders; Humans; Hydroxyindoleacetic

1996
Serotonin and aggression in children.
    Current psychiatry reports, 2000, Volume: 2, Issue:2

    Topics: Adolescent; Aggression; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorde

2000
The neuropsychopharmacology of criminality and aggression.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2001, Volume: 46, Issue:1

    Topics: Aggression; Brain; Brain Mapping; Crime; Humans; Hydroxyindoleacetic Acid; Impulsive Behavior; Neuro

2001
Aggression and central neurotransmitters.
    International review of neurobiology, 1975, Volume: 18

    Topics: Acetylcholinesterase; Aggression; Amantadine; Animals; Apomorphine; Brain; Carbachol; Choline O-Acet

1975
[Amines in mental disorders (author's transl)].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1977, Volume: 22, Issue:6

    Topics: Aggression; Biogenic Amines; Bipolar Disorder; Brain; Catecholamines; Dopamine; Emotions; Humans; Hy

1977
[Serotonin metabolism in the framework of aggression and violence].
    Duodecim; laaketieteellinen aikakauskirja, 1992, Volume: 108, Issue:3

    Topics: Aggression; Alcoholism; Brain; Female; Humans; Hydroxyindoleacetic Acid; Impulsive Behavior; Male; S

1992
Biologic correlates of suicidal risk and aggressive behavioral traits.
    Journal of clinical psychopharmacology, 1992, Volume: 12, Issue:2 Suppl

    Topics: Aggression; Alcoholism; Brain; Depressive Disorder; Humans; Hydroxyindoleacetic Acid; Impulsive Beha

1992
Aggression, suicidality, and serotonin.
    The Journal of clinical psychiatry, 1992, Volume: 53 Suppl

    Topics: Age Factors; Aggression; Alcoholism; Circadian Rhythm; Depressive Disorder; Humans; Hydroxyindoleace

1992
CSF serotonin metabolite (5-HIAA) studies in depression, impulsivity, and violence.
    The Journal of clinical psychiatry, 1990, Volume: 51 Suppl

    Topics: Aggression; Animals; Behavior, Animal; Depressive Disorder; Humans; Hydroxyindoleacetic Acid; Impuls

1990
Serotonin, suicide, and aggression: clinical studies.
    The Journal of clinical psychiatry, 1991, Volume: 52 Suppl

    Topics: Adolescent; Adult; Aggression; Brain; Female; Humans; Hydroxyindoleacetic Acid; Impulsive Behavior;

1991
The antisocial personality: a review.
    Hospital & community psychiatry, 1985, Volume: 36, Issue:8

    Topics: Adolescent; Aggression; Antisocial Personality Disorder; Behavior Therapy; Child; Child Development;

1985
Affective disorders and aggression disorders: evidence for a common biological mechanism.
    Suicide & life-threatening behavior, 1986,Summer, Volume: 16, Issue:2

    Topics: 5-Hydroxytryptophan; Aggression; Blood Platelets; Carrier Proteins; Celiac Disease; Depressive Disor

1986
Human aggression and suicide.
    Suicide & life-threatening behavior, 1986,Summer, Volume: 16, Issue:2

    Topics: Adolescent; Adult; Aggression; Animals; Depressive Disorder; Disease Models, Animal; Female; Grief;

1986
Monoamines, glucose metabolism, aggression towards self and others.
    The International journal of neuroscience, 1988, Volume: 41, Issue:3-4

    Topics: Aggression; Biogenic Monoamines; Dangerous Behavior; Humans; Hydroxyindoleacetic Acid; Hypoglycemia;

1988
Brain 5-HT and inhibition of aggressive behavior in animals: 5-HIAA and receptor subtypes.
    Psychopharmacology bulletin, 1989, Volume: 25, Issue:3

    Topics: Aggression; Animals; Brain Chemistry; Hydroxyindoleacetic Acid; Receptors, Serotonin; Serotonin

1989
The effect on aggression and mood of altering tryptophan levels.
    Nutrition reviews, 1986, Volume: 44 Suppl

    Topics: Affect; Aggression; Amino Acids; Brain; Depressive Disorder; Dietary Proteins; Humans; Hydroxyindole

1986

Trials

6 trials available for hydroxyindoleacetic acid and Aggression

ArticleYear
Effects of increasing tryptophan intake on growth and physiological changes in nursery pigs.
    Journal of animal science, 2012, Volume: 90, Issue:7

    Topics: Aggression; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Behavior, Animal; Bloo

2012
Self-rated aggression and cerebral monoaminergic turnover. Sex differences in patients with persistent depressive disorder.
    European archives of psychiatry and clinical neuroscience, 2003, Volume: 253, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aggression; Biogenic Monoamines; Brain Chemistry; Depressive Disorde

2003
Cerebrospinal fluid monoamine metabolites in boys with attention-deficit hyperactivity disorder.
    Psychiatry research, 1994, Volume: 52, Issue:3

    Topics: Aggression; Attention; Attention Deficit Disorder with Hyperactivity; Child; Dextroamphetamine; Doub

1994
Cerebrospinal fluid monoamine metabolites and glucose metabolism in posttraumatic aggression.
    Biological psychiatry, 1998, Apr-15, Volume: 43, Issue:8

    Topics: Adult; Aggression; Biogenic Monoamines; Glucose; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid

1998
Plasma monoamine metabolites and aggression: two studies of normal and oppositional defiant disorder children.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1999, Volume: 9, Issue:1-2

    Topics: Aggression; Attention Deficit and Disruptive Behavior Disorders; Biogenic Monoamines; Child; Homovan

1999
Cerebrospinal fluid and behavioral changes after methyltestosterone administration: preliminary findings.
    Archives of general psychiatry, 2001, Volume: 58, Issue:2

    Topics: Adolescent; Adult; Affect; Aggression; Anabolic Agents; Behavioral Symptoms; Brain Chemistry; Humans

2001

Other Studies

178 other studies available for hydroxyindoleacetic acid and Aggression

ArticleYear
Effects of food quantity on aggression and monoamine levels of juvenile pufferfish (Takifugu rubripes).
    Fish physiology and biochemistry, 2021, Volume: 47, Issue:6

    Topics: Aggression; Animals; Biogenic Monoamines; Brain; Diet; Dopamine; Hydroxyindoleacetic Acid; Monoamine

2021
Comparing behavioral performance and physiological responses of Sebastes schlegelii with different aggressiveness.
    Fish physiology and biochemistry, 2022, Volume: 48, Issue:5

    Topics: Aggression; Animals; Fishes; Hydrocortisone; Hydroxyindoleacetic Acid; Perciformes; Serotonin

2022
Effect of Yokukansan and Yokukansankachimpihange on Aggressive Behavior, 5-HT Receptors and Arginine Vasopressin Expression in Social Isolation-Reared Mice.
    Biological & pharmaceutical bulletin, 2019, Volume: 42, Issue:12

    Topics: Aggression; Amygdala; Animals; Arginine Vasopressin; Behavior, Animal; Drugs, Chinese Herbal; Hydrox

2019
The Levels of Monoamines and Their Metabolites in the Brain Structures of Rats Subjected to Two- and Three-Month-Long Social Isolation.
    Bulletin of experimental biology and medicine, 2020, Volume: 168, Issue:5

    Topics: Aggression; Animals; Behavior, Animal; Biogenic Monoamines; Brain; Female; Hydroxyindoleacetic Acid;

2020
Serotonin functioning and adolescents' alcohol use: A genetically informed study examining mechanisms of risk.
    Development and psychopathology, 2018, Volume: 30, Issue:1

    Topics: Adolescent; Aggression; Depression; Female; Genome-Wide Association Study; Humans; Hydroxyindoleacet

2018
CSF Apolipoprotein E in attempted suicide.
    Journal of affective disorders, 2018, 01-01, Volume: 225

    Topics: Adult; Aggression; Apolipoproteins E; Cholesterol; Female; Humans; Hydroxyindoleacetic Acid; Male; M

2018
Melatonin pretreatment attenuates acute methamphetamine-induced aggression in male ICR mice.
    Brain research, 2019, 07-15, Volume: 1715

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aggression; Animals; Brain; Dopamine; Homovanillic Acid; Hydroxyindo

2019
Whole brain monoamine detection and manipulation in a stalk-eyed fly.
    Journal of neuroscience methods, 2013, Sep-30, Volume: 219, Issue:1

    Topics: 5-Hydroxytryptophan; Aggression; Animals; Biogenic Monoamines; Brain Chemistry; Competitive Behavior

2013
Effects of feather pecking phenotype (severe feather peckers, victims and non-peckers) on serotonergic and dopaminergic activity in four brain areas of laying hens (Gallus gallus domesticus).
    Physiology & behavior, 2013, Aug-15, Volume: 120

    Topics: Aggression; Animals; Behavior, Animal; Biogenic Monoamines; Brain; Brain Chemistry; Chickens; Chroma

2013
Delay discounting task in pigs reveals response strategies related to dopamine metabolite.
    Physiology & behavior, 2013, Aug-15, Volume: 120

    Topics: Adaptation, Psychological; Aggression; Animals; Choice Behavior; Data Interpretation, Statistical; D

2013
The time course of aggressive behaviour in juvenile matrinxã Brycon amazonicus fed with dietary L-tryptophan supplementation.
    Journal of fish biology, 2014, Volume: 84, Issue:1

    Topics: Aggression; Animal Feed; Animals; Behavior, Animal; Characidae; Dietary Supplements; Hydrocortisone;

2014
Monoaminergic neurotransmitter alterations in postmortem brain regions of depressed and aggressive patients with Alzheimer's disease.
    Neurobiology of aging, 2014, Volume: 35, Issue:12

    Topics: Aged; Aged, 80 and over; Aggression; Alzheimer Disease; Brain; Chromatography, High Pressure Liquid;

2014
Social challenge increases cortisol and hypothalamic monoamine levels in matrinxã (Brycon amazonicus).
    Fish physiology and biochemistry, 2015, Volume: 41, Issue:6

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aggression; Amines; Animals; Behavior, Animal; Blood Glucose; Charac

2015
Oxytocin-Induced Changes in Monoamine Level in Symmetric Brain Structures of Isolated Aggressive C57Bl/6 Mice.
    Bulletin of experimental biology and medicine, 2016, Volume: 160, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aggression; Animals; Cerebral Cortex; Dopamine; Hippocampus; Homovan

2016
Interplay between aggression, brain monoamines and fur color mutation in the American mink.
    Genes, brain, and behavior, 2016, Volume: 15, Issue:8

    Topics: Aggression; Animals; Animals, Domestic; Behavior, Animal; Biogenic Monoamines; Brain; Brain Chemistr

2016
The effects of an anabolic androgenic steroid and low serotonin on social and non-social behaviors in male rats.
    Brain research, 2008, Sep-26, Volume: 1232

    Topics: Aggression; Anabolic Agents; Analysis of Variance; Androgens; Animals; Behavior, Animal; Chromatogra

2008
Cerebrospinal fluid monoamine metabolites and suicide.
    Nordic journal of psychiatry, 2009, Volume: 63, Issue:4

    Topics: Adult; Aggression; Depressive Disorder; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Intenti

2009
The effect of rearing experience and TPH2 genotype on HPA axis function and aggression in rhesus monkeys: a retrospective analysis.
    Hormones and behavior, 2010, Volume: 57, Issue:2

    Topics: Aggression; Animals; Environment; Genotype; Housing, Animal; Hydroxyindoleacetic Acid; Hypothalamo-H

2010
Cerebrospinal fluid 5-hydroxyindolacetic acid and homovanillic acid: reciprocal relationships with impulsive aggression in human subjects.
    Journal of neural transmission (Vienna, Austria : 1996), 2010, Volume: 117, Issue:2

    Topics: Adult; Aggression; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Impulsive Behavior;

2010
Platelet monoamine oxidase activity predicts alcohol sensitivity and voluntary alcohol intake in rhesus monkeys.
    Upsala journal of medical sciences, 2010, Volume: 115, Issue:1

    Topics: Aggression; Alcohol Drinking; Alcoholism; Animals; Behavior, Animal; Ethanol; Female; Hydroxyindolea

2010
CRF and urotensin I effects on aggression and anxiety-like behavior in rainbow trout.
    The Journal of experimental biology, 2011, Mar-15, Volume: 214, Issue:Pt 6

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aggression; Animals; Anxiety; Behavior, Animal; Corticotropin-Releas

2011
CSF 5-HIAA and exposure to and expression of interpersonal violence in suicide attempters.
    Journal of affective disorders, 2011, Volume: 132, Issue:1-2

    Topics: Adolescent; Adult; Aged; Aggression; Child; Child Abuse; Comorbidity; Female; Humans; Hydroxyindolea

2011
Behavioural and physiological correlates of impulsivity in the domestic dog (Canis familiaris).
    Physiology & behavior, 2012, Feb-01, Volume: 105, Issue:3

    Topics: Aggression; Animals; Choice Behavior; Chromatography, High Pressure Liquid; Conditioning, Operant; D

2012
Cerebrospinal fluid 5-hydroxyindolacetic acid correlates directly with negative affective intensity, but not affective lability, in human subjects.
    The international journal of neuropsychopharmacology, 2013, Volume: 16, Issue:2

    Topics: Adult; Aggression; Biogenic Monoamines; Emotions; Female; Homovanillic Acid; Humans; Hydroxyindoleac

2013
A pharmacological evidence of positive association between mouse intermale aggression and brain serotonin metabolism.
    Behavioural brain research, 2012, Jul-15, Volume: 233, Issue:1

    Topics: Aggression; Animals; Brain; Electrochemistry; Enzyme Inhibitors; Exploratory Behavior; Fenclonine; H

2012
RNA splicing and editing modulation of 5-HT(2C) receptor function: relevance to anxiety and aggression in VGV mice.
    Molecular psychiatry, 2013, Volume: 18, Issue:6

    Topics: Aggression; Animals; Anxiety; Bioluminescence Resonance Energy Transfer Techniques; Brain; Defense M

2013
Low CSF 5-HIAA level in high-lethality suicide attempters: fact or artifact?
    Biological psychiatry, 2002, Aug-15, Volume: 52, Issue:4

    Topics: Aggression; Artifacts; Data Interpretation, Statistical; Depressive Disorder; Humans; Hydroxyindolea

2002
Effects of chronic cocaine on monoamine levels in discrete brain structures of lactating rat dams.
    Pharmacology, biochemistry, and behavior, 2003, Volume: 74, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aggression; Animals; Behavior, Animal; Biogenic Monoamines; Brain Ch

2003
Physiological correlates of aggression and impulsivity in free-ranging female primates.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:6

    Topics: Aggression; Animals; Behavior, Animal; Female; Hydroxyindoleacetic Acid; Impulsive Behavior; Macaca

2003
New evidence for an association between the CSF HVA:5-HIAA ratio and psychopathic traits.
    Journal of neurology, neurosurgery, and psychiatry, 2003, Volume: 74, Issue:7

    Topics: Adolescent; Adult; Age of Onset; Aggression; Antisocial Personality Disorder; Attention Deficit Diso

2003
CSF 5-HIAA concentration as an early screening tool for predicting significant life history outcomes in female specific-pathogen-free (SPF) rhesus macaques (Macaca mulatta) maintained in captive breeding groups.
    Journal of medical primatology, 2003, Volume: 32, Issue:2

    Topics: Aggression; Animals; Animals, Zoo; Female; Housing, Animal; Hydroxyindoleacetic Acid; Macaca mulatta

2003
Cerebrospinal fluid monoamine and metabolite concentrations and aggression in rats.
    Hormones and behavior, 2003, Volume: 44, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; 5,7-Dihydroxytryptamine; Aggression; Animals; Biogenic Monoamines; C

2003
Physiological predictors of reproductive outcome and mother-infant behaviors in captive rhesus macaque females (Macaca mulatta).
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2004, Volume: 29, Issue:5

    Topics: Aggression; Animals; Animals, Newborn; Female; Homovanillic Acid; Hydrocortisone; Hydroxyindoleaceti

2004
Serotonergic response to social stress and artificial social sign stimuli during paired interactions between male Anolis carolinensis.
    Neuroscience, 2004, Volume: 123, Issue:4

    Topics: Aggression; Animals; Behavior, Animal; Brain; Brain Chemistry; Cues; Dominance-Subordination; Hydrox

2004
The control of feather pecking by serotonin.
    Behavioral neuroscience, 2004, Volume: 118, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aggression; Animals; Behavior, Animal; Brain; Brain Chemistry; Chick

2004
Biobehavioural correlates of hand preference in free-ranging female primates.
    Laterality, 2004, Volume: 9, Issue:3

    Topics: Adrenocorticotropic Hormone; Aggression; Animals; Choice Behavior; Dominance-Subordination; Female;

2004
[Neurobiology of violence: results of empirical and experimental studies of reactive violence].
    Psychiatrische Praxis, 2004, Volume: 31 Suppl 1

    Topics: Aggression; Alleles; Brain Mapping; Cerebral Cortex; Frontal Lobe; Genetic Carrier Screening; Genoty

2004
Neurobiological characteristics of rhesus macaque abusive mothers and their relation to social and maternal behavior.
    Neuroscience and biobehavioral reviews, 2005, Volume: 29, Issue:1

    Topics: Aggression; Animals; Behavior, Animal; Corticotropin-Releasing Hormone; Female; Homovanillic Acid; H

2005
Early maternal rejection affects the development of monoaminergic systems and adult abusive parenting in rhesus macaques (Macaca mulatta).
    Behavioral neuroscience, 2006, Volume: 120, Issue:5

    Topics: Age Factors; Aggression; Animals; Animals, Newborn; Brain; Female; Homovanillic Acid; Hydroxyindolea

2006
Dietary restriction changes behaviours in brain-derived neurotrophic factor heterozygous mice: role of serotonergic system.
    The European journal of neuroscience, 2006, Volume: 24, Issue:8

    Topics: Aggression; Animals; Anxiety; Behavior, Animal; Body Weight; Brain-Derived Neurotrophic Factor; Chro

2006
Behavioral effects of pubertal anabolic androgenic steroid exposure in male rats with low serotonin.
    Brain research, 2007, Feb-09, Volume: 1132, Issue:1

    Topics: Aggression; Androgens; Animals; Behavior, Animal; Brain; Down-Regulation; Female; Fenclonine; Hydrox

2007
Serotonergic influences on life-history outcomes in free-ranging male rhesus macaques.
    American journal of primatology, 2007, Volume: 69, Issue:8

    Topics: Aggression; Animals; Homovanillic Acid; Hydroxyindoleacetic Acid; Macaca mulatta; Male; Methoxyhydro

2007
Elevated testosterone and reduced 5-HIAA concentrations are associated with wounding and hantavirus infection in male Norway rats.
    Hormones and behavior, 2007, Volume: 52, Issue:4

    Topics: Adaptation, Physiological; Aggression; Animals; Animals, Wild; Brain; Chi-Square Distribution; Dopam

2007
Serotonin transporter deficiency in rats improves inhibitory control but not behavioural flexibility.
    The European journal of neuroscience, 2007, Volume: 26, Issue:7

    Topics: Aggression; Analysis of Variance; Animals; Animals, Genetically Modified; Avoidance Learning; Behavi

2007
Changes in attack behavior and activity in EphA5 knockout mice.
    Brain research, 2008, Apr-18, Volume: 1205

    Topics: Aggression; Animals; Body Weight; Brain Chemistry; Data Interpretation, Statistical; Electroshock; H

2008
Brain monoamine oxidase in mice after exposure to aggression and defeat.
    Science (New York, N.Y.), 1967, Mar-31, Volume: 155, Issue:3770

    Topics: Aggression; Amygdala; Animals; Behavior, Animal; Cerebral Cortex; Humans; Hydroxyindoleacetic Acid;

1967
[Measurement of aggressiveness by the Gottschalk and Gleser method of verbal sample analysis. Various biochemical and psychodynamic aspects].
    Acta psychiatrica Belgica, 1984, Volume: 84

    Topics: Affect; Aggression; Depressive Disorder; Hostility; Humans; Hydroxyindoleacetic Acid; Personality As

1984
Cerebrospinal fluid amine metabolites and cyclic nucleotides in human aggression [proceedings].
    Psychopharmacology bulletin, 1981, Volume: 17, Issue:1

    Topics: Adenosine Monophosphate; Adult; Aggression; Cyclic GMP; Glycols; Humans; Hydroxyindoleacetic Acid; M

1981
Neurochemical correlates of muricidal behavior in rats.
    Neuropsychobiology, 1981, Volume: 7, Issue:4

    Topics: Aggression; Agonistic Behavior; Animals; Brain Chemistry; Dopamine; Fenclonine; Humans; Hydroxyindol

1981
Dietary tryptophan reversal of septal lesion and 5,7-DHT lesion elicited shock-induced fighting.
    Pharmacology, biochemistry, and behavior, 1981, Volume: 15, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; 5,7-Dihydroxytryptamine; Aggression; Animals; Brain; Catecholamines;

1981
p-Chlorophenylalanine-induced muricidal aggression in male and female laboratory rats.
    Neuropsychobiology, 1981, Volume: 7, Issue:6

    Topics: Aggression; Animals; Brain Chemistry; Female; Fenclonine; Humans; Hydroxyindoleacetic Acid; Male; Ra

1981
L-Tryptophan's effects on mouse killing, feeding, drinking, locomotion, and brain serotonin.
    Pharmacology, biochemistry, and behavior, 1981, Volume: 15, Issue:2

    Topics: Aggression; Animals; Behavior, Animal; Brain Chemistry; Drinking Behavior; Feeding Behavior; Humans;

1981
The effect of cyproterone acetate on shock elicited aggression in rats.
    Pharmacology, biochemistry, and behavior, 1981, Volume: 15, Issue:5

    Topics: Aggression; Animals; Body Weight; Brain Chemistry; Cyproterone; Cyproterone Acetate; Electroshock; H

1981
Effect of fusaric acid on aggression, motor activity, and brain monoamines in mice.
    Pharmacology, biochemistry, and behavior, 1982, Volume: 16, Issue:1

    Topics: Aggression; Animals; Brain; Caseins; Dietary Proteins; Dopamine; Fusaric Acid; Humans; Hydroxyindole

1982
Effect of tryptophan administration on spontaneous and P-CPA-induced muricidal aggression in laboratory rats.
    Pharmacological research communications, 1981, Volume: 13, Issue:9

    Topics: Aggression; Animals; Brain Chemistry; Fenclonine; Humans; Hydroxyindoleacetic Acid; Male; Rats; Rats

1981
Aggression, suicide, and serotonin: relationships to CSF amine metabolites.
    The American journal of psychiatry, 1982, Volume: 139, Issue:6

    Topics: Adolescent; Adult; Aggression; Antisocial Personality Disorder; Borderline Personality Disorder; Bra

1982
Behavioral and biochemical changes induced by lithium and L-tryptophan in muricidal rats.
    Neuropharmacology, 1982, Volume: 21, Issue:7

    Topics: Aggression; Animals; Behavior, Animal; Biotransformation; Brain Chemistry; Humans; Hydroxyindoleacet

1982
5-hydroxytryptamine and depression: a model for the interaction of normal variance with pathology.
    British journal of clinical pharmacology, 1983, Volume: 15 Suppl 3

    Topics: Aggression; Animals; Autopsy; Biogenic Amines; Depressive Disorder; Humans; Hydroxyindoleacetic Acid

1983
CSF 5-hydroxyindoleacetic acid levels in suicidal schizophrenic patients.
    The American journal of psychiatry, 1984, Volume: 141, Issue:4

    Topics: Adult; Aggression; Female; Humans; Hydroxyindoleacetic Acid; Male; Mental Disorders; Schizophrenia;

1984
Effect of brain monoamine precursors on stress-induced behavioral and neurochemical changes in aged mice.
    Brain research, 1984, Mar-26, Volume: 296, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aggression; Animals; Biogenic Amines; Brain; Caseins; Dietary Protei

1984
Regional changes in monoamines and metabolites following defensive aggression in the rat.
    Brain research bulletin, 1984, Volume: 12, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aggression; Animals; Biogenic Amines; Brain Chemistry; Dopamine; Ele

1984
Effects of drug-induced changes in brain monoamines on aggression and motor behavior in mice.
    European journal of pharmacology, 1984, Mar-23, Volume: 99, Issue:2-3

    Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Aggression; Amphetamine; Animals; Biogenic Amin

1984
[Effect of an imidazobenzodiazepine (RO 15-1788) on aggressive behavior in mice].
    Biulleten' eksperimental'noi biologii i meditsiny, 1984, Volume: 98, Issue:10

    Topics: Aggression; Animals; Apomorphine; Benzodiazepinones; Brain; Catalepsy; Dose-Response Relationship, D

1984
Personality profiles and state aggressiveness in Finnish alcoholic, violent offenders, fire setters, and healthy volunteers.
    Archives of general psychiatry, 1994, Volume: 51, Issue:1

    Topics: Adult; Age of Onset; Aggression; Alcoholism; Aspartame; Finland; Firesetting Behavior; Forensic Psyc

1994
Are stress hormones and serotonin related to aggression in primates?
    Archives of general psychiatry, 1994, Volume: 51, Issue:1

    Topics: Adrenocorticotropic Hormone; Aggression; Animals; Humans; Hydrocortisone; Hydroxyindoleacetic Acid;

1994
5-HT-related, anxiety- and/or aggression-driven depression.
    International clinical psychopharmacology, 1994, Volume: 9 Suppl 1

    Topics: Aggression; Antidepressive Agents; Anxiety Disorders; Depressive Disorder; Humans; Hydroxyindoleacet

1994
Low CSF 5-HIAA concentrations and severe aggression and impaired impulse control in nonhuman primates.
    The American journal of psychiatry, 1994, Volume: 151, Issue:10

    Topics: Aggression; Animals; Behavior, Animal; Disruptive, Impulse Control, and Conduct Disorders; Humans; H

1994
Serotonergic control of androgen-induced dominance.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 49, Issue:2

    Topics: Aggression; Androgens; Animals; Brain Chemistry; Hydroxyindoleacetic Acid; Male; Radioligand Assay;

1994
Correlation of CSF 5-HIAA concentration with sociality and the timing of emigration in free-ranging primates.
    The American journal of psychiatry, 1995, Volume: 152, Issue:6

    Topics: Age Factors; Aggression; Animals; Behavior, Animal; Biomarkers; Grooming; Homing Behavior; Hydroxyin

1995
Brain monoamines following castration of aggressive muricidal rats.
    Neurochemical research, 1993, Volume: 18, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aggression; Animals; Biogenic Monoamines; Brain; Dopamine; Hydroxyin

1993
A longitudinal study of the relationships between psychometric test scores, offence history and the plasma concentrations of phenylacetic and 5-hydroxyindoleacetic acids in seven inmates of a prison for the psychiatrically disturbed.
    Progress in neuro-psychopharmacology & biological psychiatry, 1993, Volume: 17, Issue:4

    Topics: Adult; Aggression; Anger; Anxiety; Crime; Depression; Hostility; Humans; Hydroxyindoleacetic Acid; M

1993
Effects of monoaminergic agonists on alcohol-induced increases in mouse aggression.
    Journal of studies on alcohol. Supplement, 1993, Volume: 11

    Topics: Aggression; Animals; Behavior, Animal; Brain; Drug Synergism; Ethanol; Fenfluramine; Fluoxetine; Hyd

1993
Long-term isolation of Wistar rats alters brain monoamine turnover, blood corticosterone, and ACTH.
    Brain research bulletin, 1993, Volume: 32, Issue:6

    Topics: 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Aggression; Animals; Biogenic Monoamines; Brain; C

1993
Cerebral glucose metabolism, CSF 5-HIAA levels, and aggressive behavior in rhesus monkeys.
    The American journal of psychiatry, 1995, Volume: 152, Issue:12

    Topics: Aggression; Animals; Brain; Deoxyglucose; Drug Tolerance; Ethanol; Fluorodeoxyglucose F18; Glucose;

1995
Excessive mortality in young free-ranging male nonhuman primates with low cerebrospinal fluid 5-hydroxyindoleacetic acid concentrations.
    Archives of general psychiatry, 1996, Volume: 53, Issue:6

    Topics: Aggression; Animals; Behavior, Animal; Brain; Homovanillic Acid; Hydroxyindoleacetic Acid; Longitudi

1996
Aggression and personality: association with amino acids and monoamine metabolites.
    Psychological medicine, 1996, Volume: 26, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aggression; Amino Acids; Antisocial Personality Disorder; Blood-Brai

1996
Stability of interindividual differences in serotonin function and its relationship to severe aggression and competent social behavior in rhesus macaque females.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1996, Volume: 14, Issue:1

    Topics: Aggression; Animals; Behavior, Animal; Female; Hydroxyindoleacetic Acid; Macaca mulatta; Methoxyhydr

1996
A nonhuman primate model of type II alcoholism? Part 2. Diminished social competence and excessive aggression correlates with low cerebrospinal fluid 5-hydroxyindoleacetic acid concentrations.
    Alcoholism, clinical and experimental research, 1996, Volume: 20, Issue:4

    Topics: Adult; Age Factors; Aggression; Alcohol Drinking; Alcoholism; Animals; Antisocial Personality Disord

1996
Social attachment, brain function, and aggression.
    Annals of the New York Academy of Sciences, 1996, Sep-20, Volume: 794

    Topics: Aggression; Animals; Animals, Newborn; Brain; Female; Hydroxyindoleacetic Acid; Macaca mulatta; Male

1996
Cholesterol, serotonin, and behavior in young monkeys.
    Annals of the New York Academy of Sciences, 1996, Sep-20, Volume: 794

    Topics: Aggression; Animals; Behavior, Animal; Cholesterol; Female; Hydroxyindoleacetic Acid; Macaca; Male;

1996
Comparison of cerebrospinal fluid monoamine metabolite levels in dominant-aggressive and non-aggressive dogs.
    Brain research, 1996, Apr-01, Volume: 714, Issue:1-2

    Topics: Aggression; Animals; Biogenic Monoamines; Dogs; Homovanillic Acid; Hydroxyindoleacetic Acid

1996
CSF testosterone and 5-HIAA correlate with different types of aggressive behaviors.
    Biological psychiatry, 1996, Dec-01, Volume: 40, Issue:11

    Topics: Aggression; Aging; Animals; Body Weight; Humans; Hydroxyindoleacetic Acid; Macaca mulatta; Male; Soc

1996
Social dominance as a confounding factor in studies of primate aggression and serotonin.
    Biological psychiatry, 1997, Aug-15, Volume: 42, Issue:4

    Topics: Aggression; Animals; Hydroxyindoleacetic Acid; Male; Primates; Serotonin; Social Dominance

1997
Central serotonin activity and aggression: inverse relationship with prolactin response to d-fenfluramine, but not CSF 5-HIAA concentration, in human subjects.
    The American journal of psychiatry, 1997, Volume: 154, Issue:10

    Topics: Adult; Aggression; Brain; Female; Fenfluramine; Humans; Hydroxyindoleacetic Acid; Male; Personality

1997
CSF 5-HIAA, testosterone, and sociosexual behaviors in free-ranging male rhesus macaques in the mating season.
    Psychiatry research, 1997, Sep-19, Volume: 72, Issue:2

    Topics: Aggression; Animals; Brain; Grooming; Hydroxyindoleacetic Acid; Macaca mulatta; Male; Seasons; Serot

1997
Female social reproductive roles affect central monoamines.
    Brain research, 1997, Sep-05, Volume: 767, Issue:2

    Topics: Aggression; Animals; Biogenic Monoamines; Brain Stem; Diencephalon; Female; Hierarchy, Social; Hydro

1997
In vivo association between alcohol intoxication, aggression, and serotonin transporter availability in nonhuman primates.
    The American journal of psychiatry, 1998, Volume: 155, Issue:8

    Topics: Adult; Aggression; Alcoholic Intoxication; Alcoholism; Animals; Behavior, Animal; Brain; Brain Stem;

1998
Cerebrospinal fluid vasopressin levels: correlates with aggression and serotonin function in personality-disordered subjects.
    Archives of general psychiatry, 1998, Volume: 55, Issue:8

    Topics: Adult; Aggression; Arginine Vasopressin; Female; Fenfluramine; Humans; Hydroxyindoleacetic Acid; Imp

1998
Central serotonin depletion modulates the behavioural, endocrine and physiological responses to repeated social stress and subsequent c-fos expression in the brains of male rats.
    Neuroscience, 1999, Volume: 92, Issue:2

    Topics: 5,7-Dihydroxytryptamine; Adaptation, Psychological; Aggression; Amygdala; Animals; Body Temperature

1999
CSF 5-HIAA and aggression in female macaque monkeys: species and interindividual differences.
    Psychopharmacology, 1999, Volume: 146, Issue:4

    Topics: Aggression; Animals; Biomarkers; Female; Hydroxyindoleacetic Acid; Individuality; Macaca; Social Dom

1999
Association of aggressive behavior with altered serotonergic function in patients who are not suicidal.
    The American journal of psychiatry, 2000, Volume: 157, Issue:4

    Topics: Adult; Aggression; Brief Psychiatric Rating Scale; Female; Humans; Hydroxyindoleacetic Acid; Impulsi

2000
Estradiol modulation of central monoamine activity in female mountain spiny lizards.
    Brain, behavior and evolution, 2000, Volume: 56, Issue:4

    Topics: Aggression; Animals; Brain; Chromatography, High Pressure Liquid; Corticosterone; Dopamine; Dose-Res

2000
Brain serotonin dysfunction accounts for aggression in male mice lacking neuronal nitric oxide synthase.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Jan-30, Volume: 98, Issue:3

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Animals; Brain; Fenclonine;

2001
Brain content of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid and immune response in aggressive C57bl/6J mice.
    Bulletin of experimental biology and medicine, 2000, Volume: 130, Issue:10

    Topics: Aggression; Animals; Brain; Hydroxyindoleacetic Acid; Immunization; Mice; Mice, Inbred C57BL; Seroto

2000
Social impulsivity inversely associated with CSF 5-HIAA and fluoxetine exposure in vervet monkeys.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 24, Issue:4

    Topics: Age Factors; Aggression; Animals; Behavior, Animal; Chlorocebus aethiops; Fluoxetine; Homovanillic A

2001
[Response of the serotoninergic brain system to social stress of various duration in male mice C57BL/6J and CBA/Lac].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2001, Volume: 87, Issue:4

    Topics: Aggression; Animals; Brain; Conflict, Psychological; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inb

2001
Aggression, serotonin, and seasonality.
    The American journal of psychiatry, 2001, Volume: 158, Issue:8

    Topics: Aggression; Analysis of Variance; Humans; Hydroxyindoleacetic Acid; Research Design; Seasons; Seroto

2001
Serotonin, testosterone and alcohol in the etiology of domestic violence.
    Psychiatry research, 2001, Oct-10, Volume: 104, Issue:1

    Topics: Adult; Aggression; Alcoholism; Conditioning, Classical; Fear; Humans; Hydroxyindoleacetic Acid; Male

2001
Aggressivity, suicide attempts, and depression: relationship to cerebrospinal fluid monoamine metabolite levels.
    Biological psychiatry, 2001, Nov-15, Volume: 50, Issue:10

    Topics: Adult; Aggression; Depressive Disorder, Major; Female; Homovanillic Acid; Humans; Hydroxyindoleaceti

2001
Suppression of aggression in rainbow trout (Oncorhynchus mykiss) by dietary L-tryptophan.
    The Journal of experimental biology, 2001, Volume: 204, Issue:Pt 22

    Topics: Aggression; Animals; Behavior, Animal; Brain Chemistry; Diet; Eating; Hydrocortisone; Hydroxyindolea

2001
Study of the role of serotonin in lithium action using shock-elicited fighting.
    Communications in psychopharmacology, 1979, Volume: 3, Issue:4

    Topics: Aggression; Animals; Diet; Electroshock; Humans; Hydroxyindoleacetic Acid; Lithium; Lysergic Acid Di

1979
Aggression in humans correlates with cerebrospinal fluid amine metabolites.
    Psychiatry research, 1979, Volume: 1, Issue:2

    Topics: Adult; Aggression; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydrox

1979
Effect on rats and mice of a diet with low tryptophan content (maize flour).
    Acta physiologica latino americana, 1979, Volume: 29, Issue:4-5

    Topics: Aggression; Animals; Body Weight; Brain Stem; Diet; Female; Flour; Humans; Hydroxyindoleacetic Acid;

1979
5-hydroxytryptamine in the central nervous system and sexual receptivity of female rhesus monkeys.
    Brain research, 1975, May-02, Volume: 88, Issue:2

    Topics: Adrenalectomy; Aggression; Animals; Brain; Castration; Estradiol; Female; Fenclonine; Humans; Hydrox

1975
Effects of para-chlorophenylalanine and 5-hydroxytryptophan on mouse killing behavior in killer rats.
    Pharmacology, biochemistry, and behavior, 1978, Volume: 9, Issue:1

    Topics: 5-Hydroxytryptophan; Aggression; Animals; Behavior, Animal; Body Weight; Brain; Dose-Response Relati

1978
[REM sleep deprivation in normal humans. Changes in anxiety, depression and aggressiveness, and HVA and 5-HIAA levels in the lumbar cerebrospinal fluid].
    Bollettino della Societa italiana di biologia sperimentale, 1976, Jun-15, Volume: 52, Issue:11

    Topics: Adult; Aggression; Anxiety; Depression; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; P

1976
Altered behavioral responses to intense foot shock in socially-isolated rats.
    Pharmacology, biochemistry, and behavior, 1978, Volume: 8, Issue:1

    Topics: Aggression; Animals; Behavior, Animal; Brain; Chlorpromazine; Dopamine; Dose-Response Relationship,

1978
Manipulations of dietary tryptophan: effects on mouse killing and brain serotonin in the rat.
    Brain research, 1979, Jun-15, Volume: 169, Issue:1

    Topics: Aggression; Animals; Appetitive Behavior; Brain; Diet; Energy Intake; Humans; Hydroxyindoleacetic Ac

1979
Biogenic amines in 47, XYY syndrome.
    Neuropsychobiology, 1978, Volume: 4, Issue:6

    Topics: Adult; Aggression; Central Nervous System; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male

1978
Comparison of regional serotonin levels and turnover in the brain of naturally high and low aggressive rats.
    Brain research, 1976, Jan-23, Volume: 101, Issue:3

    Topics: Aggression; Animals; Brain; Humans; Hydroxyindoleacetic Acid; Male; Probenecid; Rats; Serotonin; Sta

1976
[Repeated arousal during non-REM sleep in normal humans. Changes in anxiety, depression and aggressiveness and HVA and 5-HIAA levels in the lumbar cerebrospinal fluid].
    Bollettino della Societa italiana di biologia sperimentale, 1976, Jun-15, Volume: 52, Issue:11

    Topics: Adult; Aggression; Anxiety; Depression; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; P

1976
[The influence of 1-DOPA on emotional responses and serotonin metabolism in the rat brain].
    Biulleten' eksperimental'noi biologii i meditsiny, 1976, Volume: 81, Issue:2

    Topics: 5-Hydroxytryptophan; Aggression; Animals; Brain; Dopamine; Emotions; Exploratory Behavior; Humans; H

1976
Role of biogenic amines in certain pathological conditions.
    Brain research, 1975, Apr-11, Volume: 87, Issue:2-3

    Topics: Acute Disease; Adult; Aggression; Biogenic Amines; Bipolar Disorder; Chlorpromazine; Chronic Disease

1975
Protein malnutrition in rats: response of brain amines and behavior to foot shock stress.
    Experimental neurology, 1975, Volume: 47, Issue:1

    Topics: Age Factors; Aggression; Animals; Animals, Newborn; Biogenic Amines; Brain Chemistry; Chronic Diseas

1975
Temporal effects of castration on emotionality and shock-induced aggression in adult male rats.
    Physiology & behavior, 1975, Volume: 14, Issue:2

    Topics: Age Factors; Aggression; Animals; Behavior, Animal; Brain; Castration; Catecholamines; Electroshock;

1975
The effects of chronic cannabis treatment upon brain 5-hydroxytryptamine, plasma corticosterone and aggressive behavior in female rats with different hormonal status.
    Psychopharmacologia, 1975, May-28, Volume: 42, Issue:2

    Topics: Aggression; Animals; Brain Chemistry; Cannabis; Castration; Corticosterone; Estradiol; Female; Gonad

1975
Changes of brain serotonin and muricide behavior following chronic administration of theophylline in rats.
    Physiology & behavior, 1975, Volume: 15, Issue:5

    Topics: Aggression; Amygdala; Animals; Brain Chemistry; Cerebral Cortex; Diencephalon; Humans; Hydroxyindole

1975
Early life undernutrition and aggression in two mouse strains.
    Developmental psychobiology, 1975, Volume: 8, Issue:3

    Topics: Aggression; Animals; Animals, Newborn; Brain; Brain Chemistry; Humans; Hydroxyindoleacetic Acid; Mal

1975
Depressed 5-hydroxyindole levels associated with hyperactive and aggressive behavior. Relationship to drug response.
    Archives of general psychiatry, 1976, Volume: 33, Issue:3

    Topics: Adolescent; Adult; Aggression; Child; Humans; Hydroxyindoleacetic Acid; Hyperkinesis; Intellectual D

1976
Changes in brain serotonergic activity during hierarchic behavior in Arctic charr (Salvelinus alpinus L.) are socially induced.
    Journal of comparative physiology. A, Sensory, neural, and behavioral physiology, 1992, Volume: 170, Issue:1

    Topics: Aggression; Animals; Biogenic Monoamines; Brain Chemistry; Fishes; Hierarchy, Social; Hydroxyindolea

1992
A 2-year prospective follow-up study of children and adolescents with disruptive behavior disorders. Prediction by cerebrospinal fluid 5-hydroxyindoleacetic acid, homovanillic acid, and autonomic measures?
    Archives of general psychiatry, 1992, Volume: 49, Issue:6

    Topics: Adolescent; Aggression; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorde

1992
Cerebrospinal fluid monoamine and adrenal correlates of aggression in free-ranging rhesus monkeys.
    Archives of general psychiatry, 1992, Volume: 49, Issue:6

    Topics: Adrenocorticotropic Hormone; Aggression; Animals; Animals, Wild; Circadian Rhythm; Hydrocortisone; H

1992
Cerebrospinal fluid monoamine metabolites, aggression, and impulsivity in disruptive behavior disorders of children and adolescents.
    Archives of general psychiatry, 1990, Volume: 47, Issue:5

    Topics: Adolescent; Age Factors; Aggression; Attention Deficit Disorder with Hyperactivity; Child; Child Beh

1990
Low CSF 5HIAA and obsessions of violence: report of two cases.
    Psychiatry research, 1990, Volume: 33, Issue:1

    Topics: Aggression; Female; Humans; Hydroxyindoleacetic Acid; Male; Obsessive-Compulsive Disorder; Thinking;

1990
Personality and cerebrospinal fluid monoamine metabolites in alcoholics and controls.
    Archives of general psychiatry, 1991, Volume: 48, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aggression; Alcoholism; Homovanillic Acid; Humans; Hydroxyind

1991
Pharmacological profile of a potential anxiolytic: AP159, a new benzothieno-pyridine derivative.
    Psychopharmacology, 1991, Volume: 104, Issue:4

    Topics: Aggression; Animals; Anti-Anxiety Agents; Avoidance Learning; Conflict, Psychological; Drinking Beha

1991
Human aggression and the role of central serotonin.
    Pharmacopsychiatry, 1985, Volume: 18, Issue:2

    Topics: Aggression; Brain; Depressive Disorder; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Interpe

1985
The effects of isolation, grouping and aggressive interactions on indole- and catecholamine levels and apparent turnover in the hypothalamus and midbrain of the male golden hamster.
    Physiology & behavior, 1985, Volume: 34, Issue:6

    Topics: Aggression; Animals; Brain; Cricetinae; Hydroxyindoleacetic Acid; Hypothalamus; Indoles; Male; Mesen

1985
Biological correlations of suicide and aggressivity in major depressions (with melancholia): 5-hydroxyindoleacetic acid and cortisol in cerebral spinal fluid, dexamethasone suppression test and therapeutic response to 5-hydroxytryptophan.
    Neuropsychobiology, 1985, Volume: 14, Issue:2

    Topics: 5-Hydroxytryptophan; Adult; Aggression; Bipolar Disorder; Carbidopa; Depressive Disorder; Dexamethas

1985
Effect of 6-OHDA injected into the locus coeruleus on apomorphine-induced aggression.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:3

    Topics: Aggression; Animals; Apomorphine; Biogenic Amines; Hydroxydopamines; Hydroxyindoleacetic Acid; Injec

1986
Biological suicide research: outcome and limitations.
    Biological psychiatry, 1986, Volume: 21, Issue:13

    Topics: Aggression; Catecholamines; Depressive Disorder; Humans; Hydrocortisone; Hydroxyindoleacetic Acid; M

1986
The effect of midazolam and beta-carboline carboxylic acid ethyl ester on behaviour, steroid hormones and central monoamine metabolites in social groups of talapoin monkeys.
    Psychopharmacology, 1986, Volume: 90, Issue:3

    Topics: Aggression; Animals; Carbolines; Cercopithecidae; Homovanillic Acid; Hormones; Hydrocortisone; Hydro

1986
Monoamines, glucose metabolism, suicidal and aggressive behaviors.
    Psychopharmacology bulletin, 1986, Volume: 22, Issue:3

    Topics: Adult; Aggression; Blood Glucose; Humans; Hydroxyindoleacetic Acid; Risk; Suicide; Suicide, Attempte

1986
(Auto)aggression and CSF 5-HIAA in depression and schizophrenia.
    Psychopharmacology bulletin, 1986, Volume: 22, Issue:3

    Topics: Aggression; Depressive Disorder; Humans; Hydroxyindoleacetic Acid; Risk; Schizophrenia; Schizophreni

1986
CSF tryptophan and transmitter amine turnover may predict social behaviour in the normal rat.
    Brain research, 1986, Dec-03, Volume: 399, Issue:1

    Topics: Aggression; Animals; Central Nervous System; Dopamine; Hydroxyindoleacetic Acid; Male; Neurotransmit

1986
Effects of chronic fenfluramine on blood serotonin, cerebrospinal fluid metabolites, and behavior in monkeys.
    Psychopharmacology, 1986, Volume: 90, Issue:4

    Topics: Aggression; Animals; Behavior, Animal; Chlorocebus aethiops; Fenfluramine; Homovanillic Acid; Hydrox

1986
Therapeutic indications for serotonin-potentiating compounds: a hypothesis.
    Biological psychiatry, 1987, Volume: 22, Issue:2

    Topics: 5-Hydroxytryptophan; Aggression; Antidepressive Agents; Anxiety; Brain; Depressive Disorder; Desipra

1987
The serotonin hypothesis of (auto)aggression. Critical appraisal of the evidence.
    Annals of the New York Academy of Sciences, 1986, Volume: 487

    Topics: Aggression; Brain; Depressive Disorder; Hostility; Humans; Hydroxyindoleacetic Acid; Lesch-Nyhan Syn

1986
Cerebrospinal fluid correlates of suicide attempts and aggression.
    Annals of the New York Academy of Sciences, 1986, Volume: 487

    Topics: Aggression; Animals; Bipolar Disorder; Depressive Disorder; Homovanillic Acid; Humans; Hydroxyindole

1986
Suicide and aggression in schizophrenia. Neurobiologic correlates.
    Annals of the New York Academy of Sciences, 1986, Volume: 487

    Topics: Aggression; Brain; Cerebral Ventricles; Dexamethasone; Homovanillic Acid; Humans; Hydrocortisone; Hy

1986
Cerebrospinal fluid studies in suicide. An overview.
    Annals of the New York Academy of Sciences, 1986, Volume: 487

    Topics: Aggression; Brain; Depressive Disorder; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methoxy

1986
Suicide, aggression, and depression. A theoretical framework for future research.
    Annals of the New York Academy of Sciences, 1986, Volume: 487

    Topics: Adoption; Aggression; Brain; Depressive Disorder; Humans; Hydroxyindoleacetic Acid; Risk; Seasons; S

1986
Conceptualizing a serotonin trait. A behavioral dimension of constraint.
    Annals of the New York Academy of Sciences, 1986, Volume: 487

    Topics: Aggression; Animals; Arousal; Brain; Dopamine; gamma-Aminobutyric Acid; Humans; Hydroxyindoleacetic

1986
Biochemical aspects of aggression in man.
    Clinical neuropharmacology, 1986, Volume: 9 Suppl 4

    Topics: Aggression; Alcoholism; Biochemical Phenomena; Biochemistry; Humans; Hydroxyindoleacetic Acid; Impul

1986
Role of central alpha 2-adrenoceptors on the development of muricidal behavior in olfactory bulbectomized rats: effect of alpha 2-adrenoceptor antagonists.
    Physiology & behavior, 1987, Volume: 39, Issue:4

    Topics: Adrenergic alpha-Antagonists; Aggression; Animals; Diencephalon; Hydroxyindoleacetic Acid; Male; Met

1987
Effects of gepirone, an aryl-piperazine anxiolytic drug, on aggressive behavior and brain monoaminergic neurotransmission.
    Naunyn-Schmiedeberg's archives of pharmacology, 1987, Volume: 335, Issue:4

    Topics: Aggression; Animals; Anti-Anxiety Agents; Biogenic Amines; Brain; Electrophysiology; Homovanillic Ac

1987
Changes of brain monoamine contents in three models of experimentally induced muricide in rats.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 26, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aggression; Animals; Biogenic Amines; Brain; Homovanillic Acid; Hydr

1987
Inhibition of mouse killing behavior by serotonin-mimetic drugs: effects of partial alterations of serotonin neurotransmission.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 27, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Animals; Citalopram; Fenclonine; Fluoxetine; Hyd

1987
Reduced central serotonin turnover in a subgroup of alcoholics?
    Progress in neuro-psychopharmacology & biological psychiatry, 1987, Volume: 11, Issue:2-3

    Topics: Aggression; Alcoholism; Blood Glucose; Brain; Firesetting Behavior; Humans; Hydroxyindoleacetic Acid

1987
Serotonergic activity and disinhibitory psychopathy in alcoholism.
    Medical hypotheses, 1987, Volume: 23, Issue:4

    Topics: Aggression; Alcoholism; Attention Deficit Disorder with Hyperactivity; Brain; Humans; Hydroxyindolea

1987
Differential influences of different stressors upon midbrain raphe neurons in rats.
    Neuroscience letters, 1987, Sep-11, Volume: 80, Issue:1

    Topics: Aggression; Animals; Electroshock; Hydroxyindoleacetic Acid; Immobilization; Male; Neurons; Physical

1987
The benefits and risks of 5-HT uptake inhibitors in depression.
    The British journal of psychiatry. Supplement, 1988, Issue:3

    Topics: Aggression; Depressive Disorder; Female; Fluoxetine; Humans; Hydroxyindoleacetic Acid; Male; Seroton

1988
Inhibitory influence of dihydroergosine on the aggressiveness of rats and mice.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 32, Issue:1

    Topics: Aggression; Animals; Ergotamines; gamma-Aminobutyric Acid; Hydroxyindoleacetic Acid; Hypothalamus; M

1989
Cruelty to animals and CSF 5HIAA.
    Psychiatry research, 1989, Volume: 28, Issue:1

    Topics: Aggression; Animal Welfare; Child; Child Behavior Disorders; Female; Follow-Up Studies; Humans; Hydr

1989
Behavior, adrenocortical activity, and brain monoamines in Norway rats selected for reduced aggressiveness towards man.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:1

    Topics: Adrenal Cortex; Aggression; Animals; Behavior, Animal; Biogenic Monoamines; Brain Chemistry; Cortico

1989
[Aggressive behavior can be the cause by low levels of serotonin and 5-HIAA].
    Lakartidningen, 1989, Sep-27, Volume: 86, Issue:39

    Topics: Aggression; Humans; Hydroxyindoleacetic Acid; Risk Factors; Serotonin

1989
Homicide, suicide and CSF 5-HIAA.
    Acta psychiatrica Scandinavica, 1985, Volume: 71, Issue:3

    Topics: Adult; Aggression; Alcoholism; Homicide; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male;

1985
Biogenic amine alterations in limbic brain regions of muricidal rats.
    Research communications in chemical pathology and pharmacology, 1985, Volume: 48, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aggression; Animals; Behavior, Animal; Biogenic Amines; Brain Chemis

1985
Effect of prolonged isolation on learning, biogenic amine turnover and aggressive behaviour in three strains of mice.
    Neuropharmacology, 1973, Volume: 12, Issue:11

    Topics: Aggression; Animals; Avoidance Learning; Behavior, Animal; Biogenic Amines; Body Weight; Humans; Hyd

1973
Influence of changes in brain monoamine metabolism on behaviour of herpes simplex-infected mice.
    Journal of the neurological sciences, 1974, Volume: 22, Issue:3

    Topics: Aggression; Animals; Apomorphine; Behavior, Animal; Brain; Clonidine; Dihydroxyphenylalanine; Diseas

1974
Behavioural effects of d-amphetamine in young chicks treated with p-Cl-phenylalanine.
    Psychopharmacologia, 1971, Volume: 20, Issue:1

    Topics: Aggression; Amphetamine; Animals; Behavior, Animal; Brain Chemistry; Chickens; Esters; Fenclonine; H

1971
Social behavior of monkeys selectively depleted of monoamines.
    Science (New York, N.Y.), 1971, Oct-22, Volume: 174, Issue:4007

    Topics: Aggression; Amines; Analysis of Variance; Animals; Behavior, Animal; Catecholamines; Catechols; Depr

1971
Inhibitory effect of dehydroepiandrosterone on aggressive behaviour.
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 196

    Topics: 17-Ketosteroids; Aggression; Animals; Behavior, Animal; Brain Chemistry; Castration; Corticosterone;

1972
[Inhibitory control of mouse-killing behaviour in the rat: serotonergic system of the raphé and olfactory input (author's transl)].
    Brain research, 1974, Apr-26, Volume: 70, Issue:3

    Topics: Aggression; Amygdala; Animals; Fenclonine; Humans; Hydroxyindoleacetic Acid; Medulla Oblongata; Neur

1974
Isolation, aggressiveness and brain 5-hydroxytryptamine turnover.
    The Journal of pharmacy and pharmacology, 1967, Volume: 19, Issue:5

    Topics: Aggression; Animals; Brain; Brain Chemistry; Environment; Environmental Exposure; Humans; Hydroxyind

1967
Proceedings: Biogenic amines and androgens in the study of aggressive behavior.
    Psychopharmacology bulletin, 1974, Volume: 10, Issue:4

    Topics: Aggression; Androgens; Animals; Biogenic Amines; Brain Chemistry; Dopamine; Humans; Hydroxyindoleace

1974
[Behavioral and biochemical effects of lesions of the raphe on rat-mouse interspecific aggressive behavior].
    Brain research, 1973, Jul-16, Volume: 57, Issue:1

    Topics: Aggression; Animals; Behavior, Animal; Humans; Hydroxyindoleacetic Acid; Medulla Oblongata; Mice; Mo

1973
Chronic administration of electroconvulsive shock effects on mouse-killing activity and brain monoamines in rats.
    Physiology & behavior, 1973, Volume: 11, Issue:5

    Topics: Aggression; Animals; Body Weight; Brain Chemistry; Disease Models, Animal; Dopamine; Electroshock; F

1973
Effects of isolation and fighting in mice on the rate of synthesis of noradrenaline, dopamine and 5-hydroxytryptamine in the brain.
    Psychopharmacologia, 1973, Oct-23, Volume: 33, Issue:1

    Topics: Aggression; Animals; Behavior, Animal; Benzyl Compounds; Brain; Brain Chemistry; Dopamine; Humans; H

1973
Behavioural and biochemical effects of 6-hydroxydopa in rats.
    Psychopharmacologia, 1974, Mar-09, Volume: 35, Issue:4

    Topics: Aggression; Animals; Behavior, Animal; Body Temperature; Brain Chemistry; Cerebellum; Cerebral Corte

1974
Time-dependent changes in brain biogenic amine dynamics following castration in male rats.
    Journal of neurochemistry, 1974, Volume: 22, Issue:6

    Topics: Aggression; Analysis of Variance; Animals; Behavior, Animal; Brain; Castration; Circadian Rhythm; Do

1974
Biochemical and behavioural changes induced by isolation in rats.
    Neuropharmacology, 1972, Volume: 11, Issue:1

    Topics: Aggression; Amines; Animals; Behavior, Animal; Biogenic Amines; Brain; Brain Chemistry; Dopamine; Hu

1972
[Aggression in rats and mice. Behavioral and biochemical aspects].
    Actualites pharmacologiques, 1971, Volume: 24

    Topics: Aggression; Amines; Animals; Aspartic Acid; Behavior, Animal; Brain; Brain Chemistry; Female; Humans

1971
Aggression in mice associated with changes in the monoamine metabolism of the brain.
    Experientia, 1969, Sep-15, Volume: 25, Issue:9

    Topics: Aggression; Animals; Behavior, Animal; Brain; Dihydroxyphenylalanine; Dopamine; Encephalitis; Fluoro

1969
Some aspects of neurochemical correlates of behavior.
    Research and clinical studies in headache, 1970, Volume: 3

    Topics: Aggression; Animals; Behavior, Animal; Brain; Brain Chemistry; Catecholamines; Dopamine; Humans; Hyd

1970
Effect of stress and para-chlorophenylalanine upon brain serotonin, 5-hydroxyindoleacetic acid and catecholamines in grouped and isolated mice.
    Biochemical pharmacology, 1968, Volume: 17, Issue:5

    Topics: Aggression; Animals; Behavior, Animal; Brain; Crowding; Depression, Chemical; Diencephalon; Dopamine

1968
Behavioral changes and 5-hydroxytryptamine turnover in animals.
    Advances in pharmacology, 1968, Volume: 6, Issue:Pt B

    Topics: Aggression; Animals; Brain; Diencephalon; Female; Humans; Hydroxyindoleacetic Acid; Male; Mesencepha

1968
Brain serotonin metabolism in isolated aggressive mice.
    Biochemical pharmacology, 1968, Volume: 17, Issue:7

    Topics: Adrenal Glands; Aggression; Animals; Body Weight; Brain; Diencephalon; Diet; Fatty Acids, Nonesterif

1968