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hydroxyindoleacetic acid and Abdominal Migraine

hydroxyindoleacetic acid has been researched along with Abdominal Migraine in 49 studies

(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.

Research Excerpts

ExcerptRelevanceReference
"We investigated the platelet and plasma levels of serotonin and its metabolite, 5-hydroxyindoleacetic acid, in patients suffering from episodic tension-type headache and migraine with and without aura, during a headache-free period."3.69Metabolism and menstrual cycle rhythmicity of serotonin in primary headaches. ( Alecci, M; Cananzi, AR; D'Andrea, G; Hasselmark, L; Perini, F; Welch, KM; Zamberlan, F, 1995)
" Main abnormalities in 5-HIAA excretion have been observed in carcinoid tumors (elevation) or hyperphenylalaninemia (diminution) as well as in migraine."3.67[5-HIAA: perspectives in nephrology]. ( Elghozi, JL; Laude, D, 1989)
"Attempts to study the biochemistry of migraine began as early as the 1960s and were primarily directed at serotonin metabolism after an increase of 5-hydroxyindoleacetic acid (5-HIAA), the main metabolite of serotonin was observed in urine of migraineurs."2.55Genetic and biochemical changes of the serotonergic system in migraine pathobiology. ( Gasparini, CF; Griffiths, LR; Smith, RA, 2017)
"The biochemistry of migraine is complex."2.38Biochemistry of migraine. ( Ferrari, MD, 1992)
"It is proposed that the migraine attack is explicable by an interaction between the brain and the cranial circulation in subjects with unstable vascular and pain-control mechanisms."2.38The pathophysiology of migraine: a tentative synthesis. ( Lance, JW, 1992)
"A nitroglycerin-induced migraine model in rats and a reserpine-induced migraine model in mice were established to investigate the effects of RCXTAs on monoamine neurotransmitters in brain tissue, including 5-hydroxytryptamine (5-HT) and its metabolite (5-HIAA)."1.51Alkaloids from the rhizomes of Ligusticum striatum exert antimigraine effects through regulating 5-HT ( Feng, R; Luo, M; Peng, C; Pu, ZH; Xie, XF; Xiong, L; Zhu, H, 2019)
"Hemiplegic migraine is a rare subtype of migraine that is associated with reversible motor weakness in the aura phase."1.46[Childhood sporadic type of hemiplegic migraine with arteria cerebri media hypoperfusion]. ( Bajzik, G; Balogh, G; Csorba, E; Lajtai, A; Nagy, C; Nagy, F; Skobrák, A; Vajda, Z, 2017)
"These findings suggest that in migraine KYN is unidirectionally metabolized into ANA at expenses of KYNA and 3-HK."1.42Altered kynurenine pathway metabolites in serum of chronic migraine patients. ( Capi, M; Curto, M; Fazio, F; Giamberardino, MA; Lionetto, L; Martelletti, P; Negro, A; Nicoletti, F; Simmaco, M, 2015)
"To evaluate the analgesic and anti-migraine activities of senkyunolide I from Ligusticum chuanxiong."1.37Effect and mechanism of senkyunolide I as an anti-migraine compound from Ligusticum chuanxiong. ( Feng, Y; He, CY; Hong, YL; Liang, S; Lin, X; Wang, YH; Xu, DS, 2011)
"Fifty children suffering from migraine as per Prensky's criteria were recruited over a period of 1 year."1.29Migraine in children. ( Banu, K; Chellaraj, M; Thilothammal, N, 1994)
"Platelets may be linked to migraine."1.29Platelet models and their possible usefulness in the study of migraine pathogenesis. ( Cananzi, AR; D'Andrea, G; Hasselmark, L; Perini, F, 1995)
"These data support the concept that migraine is at least in part a disorder of central neurotransmission."1.29Cerebrospinal fluid analyses in migraine patients and controls. ( Golbeck, A; Mar, KR; Moore, AC; Rothrock, JF; Yaksh, TL, 1995)
"In menstrual migraine 5HIAA levels and MAO activity showed similar changes with higher values in the luteal than in the follicular phase."1.29Platelet serotonin pathway in menstrual migraine. ( Alecci, M; Andrea, GD; Cananzi, A; Facchinetti, F; Fioroni, L, 1996)
"Between attacks, migraineurs had lower plasma 5-HT and higher 5-HIAA levels than did healthy controls and patients with tension headache."1.28Serotonin metabolism in migraine. ( Bruyn, GW; Ferrari, MD; Odink, J; Pennings, EJ; Tapparelli, C; Van Kempen, GM, 1989)
"In one patient with complicated migraine no change was found, and in two patients, one with common migraine and one with migraine and associated symptoms, there was a rise in total blood 5-HI during migraine attacks."1.26Total 5-hydroxyindoles in blood related to migraine attacks. ( Berstad, JR, 1976)
"After migraine attack a very pronounced lowering in excretion rate of both 5-hydroxy-indoles occured."1.25Fluctuation of 5-hydroxy-indole compounds in the urine of migrainous patients. ( Deanović, Z; Dupelj, M; Iskrić, S, 1975)

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-199032 (65.31)18.7374
1990's10 (20.41)18.2507
2000's2 (4.08)29.6817
2010's5 (10.20)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nagy, C1
Bajzik, G1
Skobrák, A1
Csorba, E1
Lajtai, A1
Balogh, G1
Nagy, F1
Vajda, Z1
Pu, ZH1
Peng, C1
Xie, XF1
Luo, M1
Zhu, H1
Feng, R1
Xiong, L1
Curto, M1
Lionetto, L1
Negro, A1
Capi, M1
Fazio, F1
Giamberardino, MA1
Simmaco, M1
Nicoletti, F1
Martelletti, P1
Gasparini, CF1
Smith, RA1
Griffiths, LR1
Wang, YH1
Liang, S1
Xu, DS1
Lin, X1
He, CY1
Feng, Y1
Hong, YL1
Blandini, F1
Rinaldi, L1
Tassorelli, C1
Sances, G1
Motta, M1
Samuele, A1
Fancellu, R1
Nappi, G5
Leon, A1
Nagata, E1
Shibata, M1
Hamada, J1
Shimizu, T1
Katoh, Y1
Gotoh, K1
Suzuki, N1
Mück-Seler, D1
Deanović, Z2
Dupelj, M2
Thilothammal, N1
Chellaraj, M1
Banu, K1
D'Andrea, G4
Hasselmark, L2
Cananzi, AR2
Alecci, M2
Perini, F2
Zamberlan, F1
Welch, KM3
Rothrock, JF1
Mar, KR1
Yaksh, TL1
Golbeck, A1
Moore, AC1
Fioroni, L1
Andrea, GD1
Cananzi, A1
Facchinetti, F1
Lambert, GA1
Shimomura, T1
Boers, PM1
Gordon, V1
Donaldson, C1
Zagami, AS1
Milovanović, DD1
Majkić-Sing, N1
Mirković, D1
Pavlović, J1
Hyypp, MT1
Kangasniemi, P2
Berstad, JR1
Kangasniemi, PJ1
Iskrić, S1
Hopf, HC1
Johnson, EA1
Gutmann, L1
Ferrari, MD2
Lance, JW5
Bousser, MG1
Elghozi, JL2
Laude, D2
Soisson, T1
Grunfeld, S2
Levine, SR1
Nagel-Leiby, S1
Joseph, R2
Hayashi, T1
Kovács, K1
Bors, L1
Tóthfalusi, L1
Jelencsik, I1
Bozsik, G1
Kerényi, L1
Komoly, S1
Odink, J1
Tapparelli, C1
Van Kempen, GM1
Pennings, EJ1
Bruyn, GW1
Riddle, JM1
Sicuteri, F3
Anselmi, B3
Fanciullacci, M3
Poloni, M4
Tartara, A1
Arrigo, A2
Bono, G2
Savoldi, F3
Kauchtschischvili, G1
Nath, K2
Sur, BK2
Tandon, RN2
Sonninen, V1
Rinne, UK1
Curran, DA2
Anthony, M2
Hinterberger, H2
Curzon, G3
Barrie, M1
Wilkinson, MI1
Stein, W1
Kawiak, W1
Stelmasiak, Z1
Gieracz, A1
Sjaastad, O1
Sjaastad, OV1
Peltola, P1
Periti, P1
Theaker, P1
Phillips, B1

Reviews

3 reviews available for hydroxyindoleacetic acid and Abdominal Migraine

ArticleYear
Genetic and biochemical changes of the serotonergic system in migraine pathobiology.
    The journal of headache and pain, 2017, Volume: 18, Issue:1

    Topics: Adult; Brain; Female; Genetic Predisposition to Disease; Humans; Hydroxyindoleacetic Acid; Male; Mig

2017
Biochemistry of migraine.
    Pathologie-biologie, 1992, Volume: 40, Issue:4

    Topics: Aspartic Acid; beta-Endorphin; Catecholamines; Enkephalin, Methionine; Estrogens; Female; Glutamates

1992
The pathophysiology of migraine: a tentative synthesis.
    Pathologie-biologie, 1992, Volume: 40, Issue:4

    Topics: Brain Stem; Calcitonin Gene-Related Peptide; Cerebrovascular Circulation; Cerebrovascular Disorders;

1992

Trials

4 trials available for hydroxyindoleacetic acid and Abdominal Migraine

ArticleYear
Peripheral levels of BDNF and NGF in primary headaches.
    Cephalalgia : an international journal of headache, 2006, Volume: 26, Issue:2

    Topics: Adult; Biomarkers; Brain-Derived Neurotrophic Factor; Cluster Headache; Female; Headache Disorders,

2006
A therapeutic trial in migraine with parachlorophenylalanine, a specific serotonin depletor.
    Headache, 1970, Volume: 10, Issue:3

    Topics: Chlorine; Clinical Trials as Topic; Female; Humans; Hydroxyindoleacetic Acid; Migraine Disorders; Ph

1970
Investigations into the mechanism and treatment of chronic headache.
    The Medical journal of Australia, 1965, Nov-27, Volume: 2, Issue:22

    Topics: Amitriptyline; Clinical Trials as Topic; Headache; Humans; Hydroxyindoleacetic Acid; Hypertension; M

1965
Total plasma serotonin, 5-hydroxyindoleacetic acid and p-hydroxy-m-methoxymandelic acid excretion in normal and migrainous subjects.
    Brain : a journal of neurology, 1965, Volume: 88, Issue:5

    Topics: Adult; Blood; Clinical Trials as Topic; Female; Humans; Hydroxyindoleacetic Acid; In Vitro Technique

1965

Other Studies

42 other studies available for hydroxyindoleacetic acid and Abdominal Migraine

ArticleYear
[Childhood sporadic type of hemiplegic migraine with arteria cerebri media hypoperfusion].
    Ideggyogyaszati szemle, 2017, Sep-30, Volume: 70, Issue:9-10

    Topics: Brain; Diagnosis, Differential; Hemiplegia; Humans; Hydroxyindoleacetic Acid; Migraine Disorders; Mu

2017
Alkaloids from the rhizomes of Ligusticum striatum exert antimigraine effects through regulating 5-HT
    Journal of ethnopharmacology, 2019, Jun-12, Volume: 237

    Topics: Alkaloids; Animals; Brain; Female; Hydroxyindoleacetic Acid; Ligusticum; Male; Mice; Migraine Disord

2019
Altered kynurenine pathway metabolites in serum of chronic migraine patients.
    The journal of headache and pain, 2015, Volume: 17

    Topics: Adult; Female; Humans; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Male; Middle Aged; Migr

2015
Effect and mechanism of senkyunolide I as an anti-migraine compound from Ligusticum chuanxiong.
    The Journal of pharmacy and pharmacology, 2011, Volume: 63, Issue:2

    Topics: 5-Hydroxytryptophan; Acetates; Analgesics; Animals; Benzofurans; Brain; Dopamine; Drugs, Chinese Her

2011
Plasma 5-hydroxytryptamine (5-HT) in migraine during an attack-free period.
    Headache, 2006, Volume: 46, Issue:4

    Topics: 5-Hydroxytryptophan; Adult; Chromatography, High Pressure Liquid; Female; Humans; Hydroxyindoleaceti

2006
Serotonin-releasing factors in migrainous patients.
    Advances in neurology, 1982, Volume: 33

    Topics: Adolescent; Adult; Biological Products; Blood Platelets; Female; Humans; Hydroxyindoleacetic Acid; M

1982
Migraine in children.
    Indian pediatrics, 1994, Volume: 31, Issue:12

    Topics: Child; Child, Preschool; Cross-Sectional Studies; Electroencephalography; Family Health; Female; Hum

1994
Metabolism and menstrual cycle rhythmicity of serotonin in primary headaches.
    Headache, 1995, Volume: 35, Issue:4

    Topics: Adolescent; Adult; Blood Platelets; Child; Female; Humans; Hydroxyindoleacetic Acid; Male; Menstrual

1995
Platelet models and their possible usefulness in the study of migraine pathogenesis.
    Cephalalgia : an international journal of headache, 1995, Volume: 15, Issue:4

    Topics: Blood Platelets; Female; Humans; Hydroxyindoleacetic Acid; Male; Migraine Disorders; Platelet Aggreg

1995
Cerebrospinal fluid analyses in migraine patients and controls.
    Cephalalgia : an international journal of headache, 1995, Volume: 15, Issue:6

    Topics: Adult; Analysis of Variance; Case-Control Studies; Female; Glutamine; Glycine; Homovanillic Acid; Hu

1995
Platelet serotonin pathway in menstrual migraine.
    Cephalalgia : an international journal of headache, 1996, Volume: 16, Issue:6

    Topics: Adult; Blood Platelets; Female; Humans; Hydroxyindoleacetic Acid; Menstrual Cycle; Menstruation Dist

1996
Serotonin infusions inhibit sensory input from the dural vasculature.
    Cephalalgia : an international journal of headache, 1999, Volume: 19, Issue:7

    Topics: Action Potentials; Animals; Cats; Chromatography, High Pressure Liquid; Cranial Sinuses; Dura Mater;

1999
Plasma and urinary serotonin and 5-hydroxyindol-3-acetic acid in adults with migraine and tension-type headache.
    Advances in experimental medicine and biology, 1999, Volume: 467

    Topics: Adult; Age of Onset; Electroencephalography; Female; Humans; Hydroxyindoleacetic Acid; Male; Middle

1999
Variation of plasma free tryptophan and CSF 5-HIAA during migraine.
    Headache, 1977, Volume: 17, Issue:1

    Topics: Adult; Female; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Migraine Disorders; Tryptophan

1977
Total 5-hydroxyindoles in blood related to migraine attacks.
    Acta neurologica Scandinavica, 1976, Volume: 54, Issue:4

    Topics: Adult; Female; Humans; Hydroxyindoleacetic Acid; Hydroxytryptophol; Indoles; Male; Middle Aged; Migr

1976
Changes in serotonin metabolism during migraine attacks.
    Monographs in neural sciences, 1976, Volume: 3

    Topics: Adult; Female; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Migraine Disorders; Serotonin; T

1976
Fluctuation of 5-hydroxy-indole compounds in the urine of migrainous patients.
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1975, Nov-10, Volume: 23, Issue:9

    Topics: Adolescent; Adult; Creatinine; Female; Humans; Hydroxyindoleacetic Acid; Middle Aged; Migraine Disor

1975
Protective effect of serotonin on migraine attacks.
    Neurology, 1992, Volume: 42, Issue:7

    Topics: Carcinoid Tumor; Humans; Hydroxyindoleacetic Acid; Ileal Neoplasms; Male; Middle Aged; Migraine Diso

1992
Urinary 5-HIAA in migraine: evidence of lowered excretion in young adult females.
    Cephalalgia : an international journal of headache, 1986, Volume: 6, Issue:4

    Topics: Adult; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Mig

1986
Reduced platelet turnover of serotonin in diet restricted migraine patients.
    Cephalalgia : an international journal of headache, 1987, Volume: 7 Suppl 6

    Topics: Adult; Blood Platelets; Female; Humans; Hydroxyindoleacetic Acid; Migraine Disorders; Serotonin

1987
Asthma and migraine--is asthma a part of acephalgic migraine? A hypothesis.
    Annals of allergy, 1988, Volume: 60, Issue:4

    Topics: Asthma; Child, Preschool; Female; Humans; Hydroxyindoleacetic Acid; Male; Medicine, Chinese Traditio

1988
Cerebrospinal fluid (CSF) investigations in migraine.
    Cephalalgia : an international journal of headache, 1989, Volume: 9, Issue:1

    Topics: Adult; Cerebrospinal Fluid Pressure; Cerebrospinal Fluid Proteins; Female; Homovanillic Acid; Humans

1989
Serotonin metabolism in migraine.
    Neurology, 1989, Volume: 39, Issue:9

    Topics: 5-Hydroxytryptophan; Headache; Humans; Hydroxyindoleacetic Acid; Migraine Disorders; Monoamine Oxida

1989
[5-HIAA: perspectives in nephrology].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1989, Volume: 183, Issue:1

    Topics: Animals; Carcinoid Tumor; Humans; Hydroxyindoleacetic Acid; Intestinal Mucosa; Kidney; Metabolic Cle

1989
Platelet serotonin metabolism and ultrastructure in migraine.
    Archives of neurology, 1989, Volume: 46, Issue:11

    Topics: Adolescent; Adult; Blood Platelets; Female; Humans; Hydroxyindoleacetic Acid; Male; Migraine Disorde

1989
Parachlorophenylalanine, an inhibitor of enteramine (serotonin) synthesis in migraine.
    Research and clinical studies in headache, 1970, Volume: 3

    Topics: Evaluation Studies as Topic; Female; Fenclonine; Humans; Hydroxyindoleacetic Acid; Migraine Disorder

1970
[Cerebrospinal fluid levels of 5-hydroxyindoleacetic acid in patients with migraine during attacks and in the intercritical period].
    Bollettino della Societa italiana di biologia sperimentale, 1974, Jul-30, Volume: 50, Issue:14

    Topics: Adult; Brain; Female; Humans; Hydroxyindoleacetic Acid; Migraine Disorders; Serotonin

1974
[Cerebrospinal fluid levels of 5-hydroxyindoleacetic acid in patients with migraine before and after treatment with L-tryptophan].
    Bollettino della Societa italiana di biologia sperimentale, 1974, Jul-30, Volume: 50, Issue:14

    Topics: Adolescent; Adult; Brain; Female; Humans; Hydroxyindoleacetic Acid; Migraine Disorders; Serotonin; T

1974
[CSF levels of 5-HIAA in migraine during tryptophan therapy (author's transl)].
    Rivista di patologia nervosa e mentale, 1974, Volume: 95, Issue:5

    Topics: Adult; Brain; Humans; Hydroxyindoleacetic Acid; Middle Aged; Migraine Disorders; Serotonin; Tryptoph

1974
Cerebrospinal fluid 5-hydroxyindoleacetic acid level in migrainous patients during spontaneous attacks, during headache-free periods and following treatment with L-tryptophan.
    Experientia, 1974, Jun-15, Volume: 30, Issue:6

    Topics: Adult; Female; Humans; Hydroxyindoleacetic Acid; Migraine Disorders; Remission, Spontaneous; Tryptop

1974
Migraine: a biochemical study.
    The Journal of the Association of Physicians of India, 1972, Volume: 20, Issue:2

    Topics: Adult; Humans; Hydroxyindoleacetic Acid; Migraine Disorders

1972
Excretion of free and conjugated 5-HIAA and VMA in urine and concentration of 5-HIAA and HVA in CSF during migraine attacks and free intervals.
    Headache, 1972, Volume: 12, Issue:2

    Topics: Adult; Female; Humans; Hydroxyindoleacetic Acid; Male; Migraine Disorders; Vanilmandelic Acid

1972
Relationships between headache and amine changes after administration of reserpine to migrainous patients.
    Journal of neurology, neurosurgery, and psychiatry, 1969, Volume: 32, Issue:6

    Topics: Adolescent; Adult; Age Factors; Creatinine; Female; Headache; Humans; Hydroxyindoleacetic Acid; Inje

1969
Effect of reserpine injections in migrainous and normal control subjects, with estimations of urinary 5-hydroxyindoleacetic acid.
    Neurology, 1969, Volume: 19, Issue:11

    Topics: Adult; Headache; Humans; Hydroxyindoleacetic Acid; Injections, Subcutaneous; Male; Migraine Disorder

1969
[Effect of Deseril-Retard and Migristen on the excretion of 5-hydroxy-indoloacetic acid and P-hydroxy-M-methoxymandelic acid in the urine of patients suffering from migraine].
    Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina, 1969, Volume: 24

    Topics: Adolescent; Adult; Amines; Child; Female; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Migra

1969
The histaminuria in vascular headache.
    Acta neurologica Scandinavica, 1970, Volume: 46, Issue:3

    Topics: Adult; Child; Female; Gastric Juice; Headache; Histamine; Humans; Hydroxyindoleacetic Acid; Male; Mi

1970
Bradykinin induced release of serotonin in man.
    Research and clinical studies in headache, 1970, Volume: 3

    Topics: Bradykinin; Dumping Syndrome; Humans; Hydroxyindoleacetic Acid; Migraine Disorders; Serotonin

1970
Serotonin and migraine.
    Transactions of the American Neurological Association, 1967, Volume: 92

    Topics: Humans; Hydroxyindoleacetic Acid; Methysergide; Migraine Disorders; Norepinephrine; Reserpine; Serot

1967
5-hydroxyindoles and migraine.
    Advances in pharmacology, 1968, Volume: 6, Issue:Pt B

    Topics: Circadian Rhythm; Humans; Hydroxyindoleacetic Acid; Indoles; Mandelic Acids; Migraine Disorders; Ser

1968
[Tryptaminuria and serotonin and catecholamine catabolism in the course of migraine].
    Bollettino della Societa italiana di biologia sperimentale, 1965, May-15, Volume: 41, Issue:9

    Topics: Catecholamines; Humans; Hydroxyindoleacetic Acid; Mandelic Acids; Migraine Disorders; Serotonin; Try

1965
Excretion of 5-hydroxyindolyl acetic acid (5HIAA) in migraine.
    Journal of neurology, neurosurgery, and psychiatry, 1966, Volume: 29, Issue:1

    Topics: Creatine; Humans; Hydroxyindoleacetic Acid; Mandelic Acids; Migraine Disorders; Tryptophan; Urine

1966
Studies in migraine.
    Proceedings of the Australian Association of Neurologists, 1966, Volume: 4

    Topics: Cyproheptadine; Ergotamine; Humans; Hydroxyindoleacetic Acid; Methysergide; Migraine Disorders; Phen

1966