hydroxyindoleacetic acid has been researched along with ADDH in 27 studies
(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Levels of CSF 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA), and 3-methoxy-4-hydroxyphenylglycol (MHPG), the metabolites of serotonin, dopamine, and norepinephrine, respectively, correlated significantly with behavioral measures of aggression and impulsivity/hyperactivity." | 5.07 | Cerebrospinal fluid monoamine metabolites in boys with attention-deficit hyperactivity disorder. ( Castellanos, FX; Elia, J; Gulotta, CS; Kruesi, MJ; Mefford, IN; Potter, WZ; Rapoport, JL; Ritchie, GF, 1994) |
| "2 years) with Attention Deficit Disorder With Hyperactivity during an initial placebo period, after four weeks of treatment with either dextroamphetamine sulfate (N=5) or a monoamine oxidase inhibitor (N=9) and at the end of a subsequent two-week placebo "washout" period." | 5.05 | Treatment of hyperactive children with monoamine oxidase inhibitors. II. Plasma and urinary monoamine findings after treatment. ( Ismond, D; Karoum, F; Linnoila, M; Murphy, DL; Potter, WZ; Rapoport, JL; Zametkin, A, 1985) |
| " The 5-hydroxyindoleacetic acid concentration significantly predicted severity of physical aggression during follow-up." | 3.68 | A 2-year prospective follow-up study of children and adolescents with disruptive behavior disorders. Prediction by cerebrospinal fluid 5-hydroxyindoleacetic acid, homovanillic acid, and autonomic measures? ( Bartko, JJ; Hamburger, SD; Hibbs, ED; Keysor, CS; Kruesi, MJ; Rapoport, JL; Zahn, TP, 1992) |
| "Cerebrospinal fluid levels of 5-hydroxyindoleacetic acid, a metabolite of serotonin, were measured in relation to aggression, impulsivity, and social functioning in 29 children and adolescents with disruptive behavior disorders." | 3.68 | Cerebrospinal fluid monoamine metabolites, aggression, and impulsivity in disruptive behavior disorders of children and adolescents. ( Brown, GL; Hamburger, S; Hibbs, E; Kruesi, MJ; Lenane, M; Potter, WZ; Rapoport, JL, 1990) |
| "To test the hypothesis that any change in urinary noradrenergic excretion accompanies drug-induced improvement in attention deficit disorder with hyperactivity, the authors gave pemoline (mean dose, 2." | 3.67 | Pemoline and urinary excretion of catecholamines and indoleamines in children with attention deficit disorder. ( Karoum, F; Linnoila, M; Sallee, R; Zametkin, AJ, 1986) |
| "Children with attention deficit disorder with hyperactivity were given either methylphenidate hydrochloride or dextroamphetamine sulfate to compare the effects on urinary excretion of catecholamines, indoleamines, and phenylethylamine (PEA)." | 3.67 | Stimulants, urinary catecholamines, and indoleamines in hyperactivity. A comparison of methylphenidate and dextroamphetamine. ( Brown, GL; Chuang, LW; Karoum, F; Linnoila, M; Rapoport, JL; Wyatt, RJ; Zametkin, AJ, 1985) |
| "Following the hypothesis that attention deficit disorder in adults (attention deficit disorder, residual type; ADD, RT), as well as in children, is associated with decreased central dopaminergic activity, the authors measured lumbar cerebrospinal fluid monoamine metabolites in a group of adults with ADD, RT and matched control subjects." | 2.65 | Cerebrospinal fluid homovanillic acid and 5-hydroxy-indoleacetic acid in adults with attention deficit disorder, residual type. ( Ebert, MH; Reimherr, FW; Wender, PH; Wood, DR, 1984) |
| "Studies have also linked alcohol abuse with aggression and criminality." | 1.27 | Serotonergic activity and disinhibitory psychopathy in alcoholism. ( Moss, HB, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (48.15) | 18.7374 |
| 1990's | 6 (22.22) | 18.2507 |
| 2000's | 6 (22.22) | 29.6817 |
| 2010's | 1 (3.70) | 24.3611 |
| 2020's | 1 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| Chatterjee, M | 1 |
| Saha, S | 1 |
| Sinha, S | 1 |
| Mukhopadhyay, K | 1 |
| Rydén, E | 1 |
| Johansson, C | 1 |
| Blennow, K | 2 |
| Landén, M | 1 |
| Moriarty, M | 1 |
| Lee, A | 1 |
| O'Connell, B | 1 |
| Kelleher, A | 1 |
| Keeley, H | 1 |
| Furey, A | 1 |
| Soderstrom, H | 1 |
| Sjodin, AK | 1 |
| Forsman, A | 1 |
| Overtoom, CC | 1 |
| Verbaten, MN | 1 |
| Kemner, C | 1 |
| Kenemans, JL | 1 |
| van Engeland, H | 1 |
| Buitelaar, JK | 1 |
| van der Molen, MW | 1 |
| van der Gugten, J | 1 |
| Westenberg, H | 1 |
| Maes, RA | 1 |
| Koelega, HS | 1 |
| Nowak, P | 1 |
| Bortel, A | 1 |
| Dabrowska, J | 1 |
| Oswiecimska, J | 1 |
| Drosik, M | 1 |
| Kwiecinski, A | 1 |
| Opara, J | 1 |
| Kostrzewa, RM | 1 |
| Brus, R | 1 |
| Hunt, RD | 1 |
| Cohen, DJ | 3 |
| Shaywitz, SE | 2 |
| Shaywitz, BA | 4 |
| Reimherr, FW | 1 |
| Wender, PH | 2 |
| Ebert, MH | 1 |
| Wood, DR | 1 |
| Sullivan, CM | 1 |
| Anderson, GM | 1 |
| Gillespie, SM | 1 |
| Sullivan, B | 1 |
| Castellanos, FX | 1 |
| Elia, J | 1 |
| Kruesi, MJ | 6 |
| Gulotta, CS | 1 |
| Mefford, IN | 1 |
| Potter, WZ | 5 |
| Ritchie, GF | 1 |
| Rapoport, JL | 7 |
| Fahlke, C | 1 |
| Hansen, S | 1 |
| Oades, RD | 1 |
| Mitsis, EM | 1 |
| Halperin, JM | 1 |
| Newcorn, JH | 1 |
| Lupandin, VM | 1 |
| Lando, LI | 1 |
| Gromova, EA | 1 |
| Kamenskaia, VM | 1 |
| Zykov, MB | 1 |
| Bowers, MB | 2 |
| Caparulo, BK | 1 |
| Hibbs, ED | 1 |
| Zahn, TP | 1 |
| Keysor, CS | 1 |
| Hamburger, SD | 3 |
| Bartko, JJ | 1 |
| Hamburger, S | 1 |
| Hibbs, E | 1 |
| Lenane, M | 1 |
| Brown, GL | 2 |
| Swedo, S | 1 |
| Leonard, H | 1 |
| Rubinow, DR | 1 |
| Zametkin, A | 1 |
| Murphy, DL | 1 |
| Linnoila, M | 3 |
| Karoum, F | 3 |
| Ismond, D | 1 |
| Zametkin, AJ | 2 |
| Sallee, R | 1 |
| Moss, HB | 1 |
| Swedo, SE | 2 |
| Rogeness, GA | 1 |
| Maas, JW | 1 |
| Javors, MA | 1 |
| Macedo, CA | 1 |
| Fischer, C | 1 |
| Harris, WR | 1 |
| Leonard, HL | 1 |
| Cheslow, DL | 1 |
| Stipetic, M | 1 |
| Chuang, LW | 1 |
| Wyatt, RJ | 1 |
| Epstein, RS | 1 |
| Kopin, IJ | 1 |
| Gordon, EK | 1 |
1 review available for hydroxyindoleacetic acid and ADDH
| Article | Year |
|---|---|
Serotonin and aggression in children.
Topics: Adolescent; Aggression; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorde | 2000 |
5 trials available for hydroxyindoleacetic acid and ADDH
| Article | Year |
|---|---|
Effects of methylphenidate, desipramine, and L-dopa on attention and inhibition in children with Attention Deficit Hyperactivity Disorder.
Topics: Attention; Attention Deficit Disorder with Hyperactivity; Child; Choice Behavior; Desipramine; Dopam | 2003 |
Cerebrospinal fluid homovanillic acid and 5-hydroxy-indoleacetic acid in adults with attention deficit disorder, residual type.
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Clinical Trials as Topic; Double-Blind Method; | 1984 |
Aspartame, behavior, and cognitive function in children with attention deficit disorder.
Topics: Adolescent; Aspartame; Attention Deficit Disorder with Hyperactivity; Catecholamines; Child; Child B | 1994 |
Cerebrospinal fluid monoamine metabolites in boys with attention-deficit hyperactivity disorder.
Topics: Aggression; Attention; Attention Deficit Disorder with Hyperactivity; Child; Dextroamphetamine; Doub | 1994 |
Treatment of hyperactive children with monoamine oxidase inhibitors. II. Plasma and urinary monoamine findings after treatment.
Topics: Amines; Attention Deficit Disorder with Hyperactivity; Child; Clinical Trials as Topic; Clorgyline; | 1985 |
21 other studies available for hydroxyindoleacetic acid and ADDH
| Article | Year |
|---|---|
A three-pronged analysis confirms the association of the serotoninergic system with attention deficit hyperactivity disorder.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Genotype; Humans; Hydroxyindoleacetic Aci | 2022 |
Lower CSF HVA and 5-HIAA in bipolar disorder type 1 with a history of childhood ADHD.
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Female; Follow-Up Studies; H | 2009 |
Development of an LC-MS/MS method for the analysis of serotonin and related compounds in urine and the identification of a potential biomarker for attention deficit hyperactivity/hyperkinetic disorder.
Topics: Attention Deficit Disorder with Hyperactivity; Calibration; Child; Chromatography, Liquid; Dopamine; | 2011 |
New evidence for an association between the CSF HVA:5-HIAA ratio and psychopathic traits.
Topics: Adolescent; Adult; Age of Onset; Aggression; Antisocial Personality Disorder; Attention Deficit Diso | 2003 |
Amphetamine and mCPP effects on dopamine and serotonin striatal in vivo microdialysates in an animal model of hyperactivity.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5,6-Dihydroxytryptamine; Age Factors; Amphetamine; Animals; Attentio | 2007 |
Strategies for study of the neurochemistry of attention deficit disorder in children.
Topics: Attention Deficit Disorder with Hyperactivity; Child; Clonidine; Dopamine beta-Hydroxylase; Growth H | 1982 |
Alcohol responsiveness, hyperreactivity, and motor restlessness in an animal model for attention-deficit hyperactivity disorder.
Topics: Alcohol Drinking; Animals; Attention Deficit Disorder with Hyperactivity; Brain Chemistry; Diazepam; | 1999 |
Differential measures of 'sustained attention' in children with attention-deficit/hyperactivity or tic disorders: relations to monoamine metabolism.
Topics: Adolescent; Attention; Attention Deficit Disorder with Hyperactivity; Biogenic Monoamines; Case-Cont | 2000 |
[Role of biogenic amines in the pathogenesis of intellectual disorders in children with minimal psychoorganic syndromes].
Topics: Attention Deficit Disorder with Hyperactivity; Catecholamines; Child; Dihydroxyphenylalanine; Electr | 1978 |
CSF monoamine metabolites in children with minimal brain dysfunction: evidence for alteration of brain dopamine. A preliminary report.
Topics: Attention Deficit Disorder with Hyperactivity; Biogenic Amines; Brain; Child; Child, Preschool; Dopa | 1977 |
Dopamine and serotonin metabolism in neuropsychiatrically disturbed children. CSF homovanillic acid and 5-hydroxyindoleacetic acid.
Topics: Adolescent; Age Factors; Aphasia; Attention Deficit Disorder with Hyperactivity; Autistic Disorder; | 1977 |
A 2-year prospective follow-up study of children and adolescents with disruptive behavior disorders. Prediction by cerebrospinal fluid 5-hydroxyindoleacetic acid, homovanillic acid, and autonomic measures?
Topics: Adolescent; Aggression; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorde | 1992 |
Cerebrospinal fluid monoamine metabolites, aggression, and impulsivity in disruptive behavior disorders of children and adolescents.
Topics: Adolescent; Age Factors; Aggression; Attention Deficit Disorder with Hyperactivity; Child; Child Beh | 1990 |
CSF somatostatin in childhood psychiatric disorders: a preliminary investigation.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorders; Depressi | 1990 |
Pemoline and urinary excretion of catecholamines and indoleamines in children with attention deficit disorder.
Topics: Attention Deficit Disorder with Hyperactivity; Child; Dextroamphetamine; Humans; Hydroxyindoleacetic | 1986 |
Serotonergic activity and disinhibitory psychopathy in alcoholism.
Topics: Aggression; Alcoholism; Attention Deficit Disorder with Hyperactivity; Brain; Humans; Hydroxyindolea | 1987 |
Concentration gradient of CSF monoamine metabolites in children and adolescents.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorders; Child De | 1988 |
Attention deficit disorder symptoms and urine catecholamines.
Topics: Attention Deficit Disorder with Hyperactivity; Catecholamines; Child; Dopamine; Dopamine beta-Hydrox | 1989 |
Lack of seasonal variation in pediatric lumbar cerebrospinal fluid neurotransmitter metabolite concentrations.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorders; Female; | 1989 |
Stimulants, urinary catecholamines, and indoleamines in hyperactivity. A comparison of methylphenidate and dextroamphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Attention Deficit Disorder with Hyperactivity; Catecholamines; Child | 1985 |
Urinary monoamine metabolites in children with minimal brain dysfunction.
Topics: Adolescent; Antidepressive Agents; Attention Deficit Disorder with Hyperactivity; Brain Damage, Chro | 1971 |