hydroxygenkwanin has been researched along with Lung-Neoplasms* in 1 studies
1 other study(ies) available for hydroxygenkwanin and Lung-Neoplasms
Article | Year |
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Hydroxygenkwanin Suppresses Non-Small Cell Lung Cancer Progression by Enhancing EGFR Degradation.
Epidermal growth factor receptor (EGFR) is frequently overexpressed and mutated in non-small cell lung cancer (NSCLC), which is the major type of lung cancer. The EGFR tyrosine kinase inhibitors (TKIs) are the approved treatment for patients harboring activating mutations in the EGFR kinase. However, most of the patients treated with EGFR-TKIs developed resistance. Therefore, the development of compounds exhibiting unique antitumor activities might help to improve the management of NSCLC patients. The total flavonoids from Topics: A549 Cells; Carcinoma, Non-Small-Cell Lung; Cell Survival; Daphne; ErbB Receptors; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Neoplasm Proteins; Proteolysis; Signal Transduction; Transcriptome | 2020 |