hydroxyethylcellulose has been researched along with Vaginal-Diseases* in 1 studies
1 other study(ies) available for hydroxyethylcellulose and Vaginal-Diseases
| Article | Year |
|---|---|
Susceptibility of Chlamydia trachomatis to the excipient hydroxyethyl cellulose: pH and concentration dependence of antimicrobial activity.
Hydroxyethyl cellulose (HEC) is used as a neutral excipient in microbicides used against sexually transmitted pathogens. However, HEC inhibits the infection of cervical epithelial cells by Chlamydia trachomatis at pH 5 in a concentration-dependent manner. At pH 7, infection is inversely dependent on the concentration of HEC, possibly due to pH-dependent calcium sequestration. Topics: Administration, Intravaginal; Anti-Bacterial Agents; Bacterial Adhesion; Cellulose; Chlamydia Infections; Chlamydia trachomatis; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Resistance, Bacterial; Excipients; Female; HeLa Cells; Humans; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Vaginal Diseases | 2008 |