hydroxychloroquine has been researched along with Xerostomia in 6 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Xerostomia: Decreased salivary flow.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydroxychloroquine was most frequently used (88." | 1.62 | Clinical features and outcomes from the Singapore Sjögren's syndrome study. ( Charan, N; Kam, JK; Leong, RW; Loh, ZW; Thong, BY, 2021) |
| "Although renal tubular acidosis (RTA), secondary to autoimmune interstitial nephritis, develops in a large proportion of patients with Sjögren's syndrome (SS), most of the subjects are asymptomatic." | 1.33 | A primary Sjögren's syndrome patient with distal renal tubular acidosis, who presented with symptoms of hypokalemic periodic paralysis: Report of a case study and review of the literature. ( Celik, Y; Gerenli, M; Pamuk, ON; Soy, M, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Kam, JK | 1 |
| Charan, N | 1 |
| Leong, RW | 1 |
| Loh, ZW | 1 |
| Thong, BY | 1 |
| Rihl, M | 1 |
| Ulbricht, K | 1 |
| Schmidt, RE | 1 |
| Witte, T | 1 |
| Yavuz, S | 1 |
| Asfuroğlu, E | 1 |
| Bicakcigil, M | 1 |
| Toker, E | 1 |
| Cankaya, H | 1 |
| Alpöz, E | 1 |
| Karabulut, G | 1 |
| Güneri, P | 1 |
| Boyacioglu, H | 1 |
| Kabasakal, Y | 1 |
| Soy, M | 1 |
| Pamuk, ON | 1 |
| Gerenli, M | 1 |
| Celik, Y | 1 |
| Fox, RI | 1 |
| Dixon, R | 1 |
| Guarrasi, V | 1 |
| Krubel, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Analysis of Hydroxychloroquine Blood Levels in Patients With Primary Sjögren Syndrome and Possible Correlation With the Disease Activity[NCT04546542] | 75 participants (Anticipated) | Observational | 2020-10-01 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for hydroxychloroquine and Xerostomia
| Article | Year |
|---|---|
Effects of hydroxychloroquine on salivary flow rates and oral complaints of Sjögren patients: a prospective sample study.
Topics: Adult; Aged; Burning Mouth Syndrome; Cheilitis; Cholinesterase Inhibitors; Deglutition; Enzyme Inhib | 2010 |
Treatment of primary Sjögren's syndrome with hydroxychloroquine: a retrospective, open-label study.
Topics: Adolescent; Adult; Aged; Antimalarials; Antirheumatic Agents; Child; Female; Humans; Hydroxychloroqu | 1996 |
4 other studies available for hydroxychloroquine and Xerostomia
| Article | Year |
|---|---|
Clinical features and outcomes from the Singapore Sjögren's syndrome study.
Topics: Adult; Arthralgia; Azathioprine; Female; Humans; Hydroxychloroquine; Keratoconjunctivitis Sicca; Mal | 2021 |
Treatment of sicca symptoms with hydroxychloroquine in patients with Sjogren's syndrome.
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Autoantibodies; Carrier Proteins; Female; Huma | 2009 |
Hydroxychloroquine improves dry eye symptoms of patients with primary Sjogren's syndrome.
Topics: Adult; Aged; B-Cell Activating Factor; Biomarkers; Female; Humans; Hydroxychloroquine; Keratoconjunc | 2011 |
A primary Sjögren's syndrome patient with distal renal tubular acidosis, who presented with symptoms of hypokalemic periodic paralysis: Report of a case study and review of the literature.
Topics: Acidosis, Renal Tubular; Adult; Antirheumatic Agents; Diagnosis, Differential; Drug Therapy, Combina | 2005 |