hydroxychloroquine has been researched along with Viral Diseases in 3 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Effective treatment of retinal diseases with adeno-associated virus (AAV)-mediated gene therapy is highly dependent on the proportion of successfully transduced cells." | 2.66 | Immunomodulatory Effects of Hydroxychloroquine and Chloroquine in Viral Infections and Their Potential Application in Retinal Gene Therapy. ( Barnard, AR; Chandler, LC; MacLaren, RE; McClements, ME; Xue, K; Yusuf, IH, 2020) |
| " A physiologically based pharmacokinetic model with detailed respiratory physiology was used to predict regional airway exposure and optimize dosing regimens." | 1.72 | Translational Modeling of Chloroquine and Hydroxychloroquine Dosimetry in Human Airways for Treating Viral Respiratory Infections. ( Calvino-Martin, F; Hoeng, J; Kolli, AR, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Kolli, AR | 1 |
| Calvino-Martin, F | 1 |
| Hoeng, J | 1 |
| Chandler, LC | 1 |
| Yusuf, IH | 1 |
| McClements, ME | 1 |
| Barnard, AR | 1 |
| MacLaren, RE | 1 |
| Xue, K | 1 |
| Rolain, JM | 1 |
| Colson, P | 1 |
| Raoult, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Rapid Development and Implementation of a Remote ECG-monitored Prospective Randomized Clinical Trial During a Pandemic: Hydroxychloroquine Prophylaxis in COVID-19 Household Contacts[NCT04652648] | Phase 4 | 54 participants (Actual) | Interventional | 2020-05-27 | Completed | ||
| A Randomized Trial of Efficacy and Safety of an Early OUTpatient Treatment of COVID-19 in Patients With Risk Factor for Poor Outcome: a Strategy to Prevent Hospitalization[NCT04365582] | Phase 3 | 0 participants (Actual) | Interventional | 2020-05-07 | Withdrawn (stopped due to The PI decided.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for hydroxychloroquine and Viral Diseases
| Article | Year |
|---|---|
Immunomodulatory Effects of Hydroxychloroquine and Chloroquine in Viral Infections and Their Potential Application in Retinal Gene Therapy.
Topics: Animals; Betacoronavirus; Chloroquine; Dependovirus; Genetic Therapy; Humans; Hydroxychloroquine; Im | 2020 |
Recycling of chloroquine and its hydroxyl analogue to face bacterial, fungal and viral infections in the 21st century.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Antiviral Agents; Bacterial Infecti | 2007 |
Recycling of chloroquine and its hydroxyl analogue to face bacterial, fungal and viral infections in the 21st century.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Antiviral Agents; Bacterial Infecti | 2007 |
Recycling of chloroquine and its hydroxyl analogue to face bacterial, fungal and viral infections in the 21st century.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Antiviral Agents; Bacterial Infecti | 2007 |
Recycling of chloroquine and its hydroxyl analogue to face bacterial, fungal and viral infections in the 21st century.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Antiviral Agents; Bacterial Infecti | 2007 |
1 other study available for hydroxychloroquine and Viral Diseases
| Article | Year |
|---|---|
Translational Modeling of Chloroquine and Hydroxychloroquine Dosimetry in Human Airways for Treating Viral Respiratory Infections.
Topics: Administration, Inhalation; Aerosols; Algorithms; Cell Line; Chloroquine; COVID-19; Cytosol; Humans; | 2022 |