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hydroxychloroquine and Venous Thrombosis

hydroxychloroquine has been researched along with Venous Thrombosis in 9 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Venous Thrombosis: The formation or presence of a blood clot (THROMBUS) within a vein.

Research Excerpts

ExcerptRelevanceReference
"Hydroxychloroquine (HCQ) has a primary role in the prophylaxis and treatment of systemic lupus erythematosus (SLE) and may be protective against thrombosis in SLE."8.02Association of Higher Hydroxychloroquine Blood Levels With Reduced Thrombosis Risk in Systemic Lupus Erythematosus. ( Goldman, DW; Konig, MF; Li, J; Petri, M, 2021)
"Hydroxychloroquine (HCQ) has a primary role in the prophylaxis and treatment of systemic lupus erythematosus (SLE) and may be protective against thrombosis in SLE."4.02Association of Higher Hydroxychloroquine Blood Levels With Reduced Thrombosis Risk in Systemic Lupus Erythematosus. ( Goldman, DW; Konig, MF; Li, J; Petri, M, 2021)
"Severe and potentially fatal deep cerebral thrombosis may complicate the initial clinical presentation of COVID-19."1.56Cerebral Venous Thrombosis Associated with COVID-19. ( Cavalcanti, DD; Dehkharghani, S; Jain, R; Lillemoe, K; Nelson, PK; Nossek, E; Radmanesh, A; Raz, E; Riina, HA; Shapiro, M; Torres, J; Yaghi, S, 2020)
"Hydroxychloroquine (HCQ) has been used for decades to treat patients with rheumatic diseases, for example, systemic lupus erythematosus (SLE), rheumatoid arthritis or the antiphospholipid syndrome (APS)."1.46Hydroxychloroquine inhibits proinflammatory signalling pathways by targeting endosomal NADPH oxidase. ( Canisius, A; Lackner, KJ; Manukyan, D; Müller-Calleja, N; Strand, D, 2017)
"Thus, the pregnancy was considered a high-risk pregnancy."1.42[Systemic lupus erythematosus and a medical history of deep vein thrombosis in a 27-year-old pregnant woman]. ( Puppe, V, 2015)
"Intrahepatic hemorrhage is a very rare complication of warfarin, and our patient experienced intrahepatic and subgaleal hemorrhage although she did not have any risk factors for bleeding or instability of the international normalized ratio control."1.39Simultaneous intrahepatic and subgaleal hemorrhage in antiphospholipid syndrome following anticoagulation therapy. ( Baek, YH; Cho, DS; Chung, WT; Han, SY; Kang, SH; Lee, SW; Park, IC, 2013)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's6 (66.67)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Cavalcanti, DD1
Raz, E1
Shapiro, M1
Dehkharghani, S1
Yaghi, S1
Lillemoe, K1
Nossek, E1
Torres, J1
Jain, R1
Riina, HA1
Radmanesh, A1
Nelson, PK1
Petri, M1
Konig, MF1
Li, J1
Goldman, DW1
Dyer, MR1
Alexander, W1
Hassoune, A1
Chen, Q1
Brzoska, T1
Alvikas, J1
Liu, Y1
Haldeman, S1
Plautz, W1
Loughran, P1
Li, H1
Boone, B1
Sadovsky, Y1
Sundd, P1
Zuckerbraun, BS1
Neal, MD1
Park, IC1
Baek, YH1
Han, SY1
Lee, SW2
Chung, WT1
Kang, SH1
Cho, DS1
Puppe, V1
Müller-Calleja, N1
Manukyan, D1
Canisius, A1
Strand, D1
Lackner, KJ1
Wang, TF1
Lim, W1
Richmond, BW1
Cole, MB1
Dash, A1
Eyler, A1
Boomershine, CS1
Chen, HC1
Lai, JH1
Huang, GS1
Gao, HW1
Chen, CH1
Kuo, SY1
Chang, DM1

Reviews

2 reviews available for hydroxychloroquine and Venous Thrombosis

ArticleYear
What is the role of hydroxychloroquine in reducing thrombotic risk in patients with antiphospholipid antibodies?
    Hematology. American Society of Hematology. Education Program, 2016, Dec-02, Volume: 2016, Issue:1

    Topics: Adult; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Humans; Hydroxychloroquine; Male; Ve

2016
Systemic lupus erythematosus with simultaneous onset of Kikuchi-Fujimoto's disease complicated with antiphospholipid antibody syndrome: a case report and review of the literature.
    Rheumatology international, 2005, Volume: 25, Issue:4

    Topics: Administration, Oral; Adult; Anti-Inflammatory Agents; Anticoagulants; Antiphospholipid Syndrome; An

2005

Other Studies

7 other studies available for hydroxychloroquine and Venous Thrombosis

ArticleYear
Cerebral Venous Thrombosis Associated with COVID-19.
    AJNR. American journal of neuroradiology, 2020, Volume: 41, Issue:8

    Topics: Adult; Azithromycin; Betacoronavirus; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Fem

2020
Association of Higher Hydroxychloroquine Blood Levels With Reduced Thrombosis Risk in Systemic Lupus Erythematosus.
    Arthritis & rheumatology (Hoboken, N.J.), 2021, Volume: 73, Issue:6

    Topics: Adult; Antirheumatic Agents; Chromatography, Liquid; Female; Fingers; Gangrene; Humans; Hydroxychlor

2021
Platelet-derived extracellular vesicles released after trauma promote hemostasis and contribute to DVT in mice.
    Journal of thrombosis and haemostasis : JTH, 2019, Volume: 17, Issue:10

    Topics: Adult; Aged; Animals; Blood Platelets; Disease Models, Animal; Extracellular Vesicles; Female; Fibri

2019
Simultaneous intrahepatic and subgaleal hemorrhage in antiphospholipid syndrome following anticoagulation therapy.
    World journal of gastroenterology, 2013, Oct-14, Volume: 19, Issue:38

    Topics: Adolescent; Anticoagulants; Antiphospholipid Syndrome; Chemical and Drug Induced Liver Injury; Clopi

2013
[Systemic lupus erythematosus and a medical history of deep vein thrombosis in a 27-year-old pregnant woman].
    Der Internist, 2015, Volume: 56, Issue:3

    Topics: Adult; Antirheumatic Agents; Female; Fibrinolytic Agents; Heparin, Low-Molecular-Weight; Humans; Hyd

2015
Hydroxychloroquine inhibits proinflammatory signalling pathways by targeting endosomal NADPH oxidase.
    Annals of the rheumatic diseases, 2017, Volume: 76, Issue:5

    Topics: Adult; Aged; Animals; Antibodies, Antiphospholipid; Antirheumatic Agents; Cells, Cultured; Disease M

2017
A tale of two rashes.
    The American journal of medicine, 2011, Volume: 124, Issue:5

    Topics: Aged; Antihypertensive Agents; Azathioprine; Complement C4; Cryoglobulinemia; Diagnosis, Differentia

2011