Page last updated: 2024-10-28

hydroxychloroquine and Vasculitis

hydroxychloroquine has been researched along with Vasculitis in 27 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Vasculitis: Inflammation of any one of the blood vessels, including the ARTERIES; VEINS; and rest of the vasculature system in the body.

Research Excerpts

ExcerptRelevanceReference
"Methotrexate is successfully used in the treatment of arthritis but little is known about its effects on extra-articular manifestations of rheumatoid arthritis."7.68Accelerated nodulosis and systemic manifestations during methotrexate therapy for rheumatoid arthritis. ( Anaya, JM; Combe, B; Didry, C; Gutierrez, M; Sany, J, 1993)
" Studies included were trials in which: (1) the participants were classified as having GCA by the 1990 ACR criteria or biopsy proven disease; (2) parallel-group randomised control of at least 16 weeks duration had been conducted with at least 20 participants; (3) the design included either alternative adjunct immunosuppressant regimens, alternative GCs dosing or routes of administration; and (4) outcome data was included on either relapse rates or rates of infection."6.50Prednisolone combined with adjunctive immunosuppression is not superior to prednisolone alone in terms of efficacy and safety in giant cell arteritis: meta-analysis. ( Loke, YK; MacGregor, AJ; Watts, RA; Yates, M, 2014)
" Treatment of the patient with prednisone, colchicine and hydroxychloroquine led to the improvement of the cutaneous vasculitis and a drop in ESR, serum gamma globulins and IgM and IgG rheumatoid factors."4.79Hypergammaglobulinemic purpura of Waldenstrom associated with systemic lupus erythematosus: report of a case and review of the literature. ( Habib, GS; Quismorio, FP; Stimmer, MM, 1995)
" The patient received induction therapy with steroids, cyclophosphamide and hydroxychloroquine followed by rapid clinical improvement and remission of proteinuria."3.96A case report of hypocomplementemic urticarial vasculitis presenting with membranoproliferative glomerulonephritis. ( Boletis, JN; Liapis, G; Marinaki, S; Skalioti, C; Vallianou, K, 2020)
"Methotrexate is successfully used in the treatment of arthritis but little is known about its effects on extra-articular manifestations of rheumatoid arthritis."3.68Accelerated nodulosis and systemic manifestations during methotrexate therapy for rheumatoid arthritis. ( Anaya, JM; Combe, B; Didry, C; Gutierrez, M; Sany, J, 1993)
"The pandemic outbreak of coronavirus disease 2019 (COVID-19) is rapidly spreading all over the world."2.66The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China. ( Li, T; Liu, Z; Qin, Y; Wang, J; Wang, Q; Yan, X; Zeng, X; Zhang, F; Zhang, S; Zhang, W; Zhang, X; Zhao, Y, 2020)
" Studies included were trials in which: (1) the participants were classified as having GCA by the 1990 ACR criteria or biopsy proven disease; (2) parallel-group randomised control of at least 16 weeks duration had been conducted with at least 20 participants; (3) the design included either alternative adjunct immunosuppressant regimens, alternative GCs dosing or routes of administration; and (4) outcome data was included on either relapse rates or rates of infection."2.50Prednisolone combined with adjunctive immunosuppression is not superior to prednisolone alone in terms of efficacy and safety in giant cell arteritis: meta-analysis. ( Loke, YK; MacGregor, AJ; Watts, RA; Yates, M, 2014)
"Diffuse alveolar hemorrhage is an uncommon and often fatal condition in children that is characterized by distinct histopathological etiologies."1.51Acute pulmonary embolism in a child with ANCA-negative Idiopathic Pulmonary Capillaritis. ( Asseri, AA; Daines, CL; Zeng, Y, 2019)
"Hydroxychloroquine was the most frequently filled DMARD (13."1.46End-stage renal disease in patients with rheumatoid arthritis. ( Bethel, M; Brown, S; Carbone, L; Chen, CC; Nahman, NS; Paudyal, S; Rice, C; Skelton, M; Yang, FM, 2017)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19903 (11.11)18.7374
1990's4 (14.81)18.2507
2000's3 (11.11)29.6817
2010's12 (44.44)24.3611
2020's5 (18.52)2.80

Authors

AuthorsStudies
Su, L1
Qi, Z1
Guan, S1
Wei, L1
Zhao, Y2
Zhang, W1
Zhang, F1
Wang, Q1
Li, T1
Liu, Z1
Wang, J1
Qin, Y1
Zhang, X1
Yan, X1
Zeng, X1
Zhang, S1
Vallianou, K1
Skalioti, C1
Liapis, G1
Boletis, JN1
Marinaki, S1
Murray, K1
Quinn, S1
Turk, M1
O'Rourke, A1
Molloy, E1
O'Neill, L1
Mongey, AB1
Fearon, U1
Veale, DJ1
Bostan, E1
Akdogan, N1
Gokoz, O1
Dogan, S1
Jachiet, M2
Flageul, B2
Bouaziz, JD2
Bagot, M2
Terrier, B2
Asseri, AA1
Zeng, Y1
Daines, CL1
Shadhu, K1
Ramlagun, D1
Ping, X1
Yates, M1
Loke, YK1
Watts, RA1
MacGregor, AJ1
Deroux, A1
Le Quellec, A1
Maurier, F1
Cordoliani, F1
Godmer, P1
Abasq, C1
Astudillo, L1
Belenotti, P1
Bessis, D1
Bigot, A1
Doutre, MS1
Ebbo, M1
Guichard, I1
Hachulla, E1
Héron, E1
Jeudy, G1
Jourde-Chiche, N1
Jullien, D1
Lavigne, C1
Machet, L1
Macher, MA1
Martel, C1
Melboucy-Belkhir, S1
Morice, C1
Petit, A1
Simorre, B1
Zenone, T1
Bouillet, L1
Frémeaux-Bacchi, V1
Guillevin, L1
Mouthon, L1
Dupin, N1
Aractingi, S1
Freitas, A1
Senra, V1
Marinho, A1
Guedes, M1
Kibune, N1
Shimomura, Y1
Hasegawa, A1
Saeki, T1
Umemori, Y1
Abe, R1
Paudyal, S1
Yang, FM1
Rice, C1
Chen, CC1
Skelton, M1
Bethel, M1
Brown, S1
Nahman, NS1
Carbone, L1
Okan, G1
Karaaslan, M1
Büyükbabani, N1
Rozin, AP1
Egozi, D1
Ramon, Y1
Toledano, K1
Braun-Moscovici, Y1
Markovits, D1
Schapira, D1
Bergman, R1
Melamed, Y1
Ullman, Y1
Balbir-Gurman, A1
Hasiloglu, ZI1
Albayram, S1
Tasmali, K1
Erer, B1
Selcuk, H1
Islak, C1
Hong, JY1
Lai, CC1
Chang, YS1
Hsiao, KH1
Chou, CT1
Chen, WS1
Francès, C2
Barete, S2
Ayoub, N1
Piette, JC2
RUBENSTEIN, M1
WOLFF, SM1
Lai, TY1
Chan, WM1
Li, H1
Lai, RY1
Lam, DS1
Le Pelletier, F1
Amoura, Z1
Lopez, LR1
Davis, KC1
Kohler, PF1
Schocket, AL1
Habib, GS1
Stimmer, MM1
Quismorio, FP1
Neumann, R1
Foster, CS1
Combe, B1
Didry, C1
Gutierrez, M1
Anaya, JM1
Sany, J1
Krendel, DA1
Costigan, DA1
Dugowson, CE1
Gilliland, BC1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Nutritional Habits, Does it Affect Coronavirus Disease 2019 (COVID-19) Infection Outcome? An Egyptian Experience[NCT04447144]200 participants (Anticipated)Observational2020-06-01Recruiting
Evaluation of Independent Clinical- Laboratory Predictors of Clinical Outcomes in Hospitalized Positive SARS-CoV2 Patients (Outcomes SARS-CoV2)[NCT05162534]1,800 participants (Actual)Observational2020-05-29Completed
Comparison of Cytokine Hemadsorption as an Immunomodulator Therapy in Covid 19 Patients With and Without Bacterial Sepsis[NCT04920851]23 participants (Anticipated)Observational2021-06-10Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for hydroxychloroquine and Vasculitis

ArticleYear
The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China.
    Clinical immunology (Orlando, Fla.), 2020, Volume: 214

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Betacoronavirus; Chloroquine; Coronavir

2020
The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China.
    Clinical immunology (Orlando, Fla.), 2020, Volume: 214

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Betacoronavirus; Chloroquine; Coronavir

2020
The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China.
    Clinical immunology (Orlando, Fla.), 2020, Volume: 214

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Betacoronavirus; Chloroquine; Coronavir

2020
The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China.
    Clinical immunology (Orlando, Fla.), 2020, Volume: 214

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Betacoronavirus; Chloroquine; Coronavir

2020
The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China.
    Clinical immunology (Orlando, Fla.), 2020, Volume: 214

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Betacoronavirus; Chloroquine; Coronavir

2020
The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China.
    Clinical immunology (Orlando, Fla.), 2020, Volume: 214

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Betacoronavirus; Chloroquine; Coronavir

2020
The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China.
    Clinical immunology (Orlando, Fla.), 2020, Volume: 214

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Betacoronavirus; Chloroquine; Coronavir

2020
The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China.
    Clinical immunology (Orlando, Fla.), 2020, Volume: 214

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Betacoronavirus; Chloroquine; Coronavir

2020
The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China.
    Clinical immunology (Orlando, Fla.), 2020, Volume: 214

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Betacoronavirus; Chloroquine; Coronavir

2020
Prednisolone combined with adjunctive immunosuppression is not superior to prednisolone alone in terms of efficacy and safety in giant cell arteritis: meta-analysis.
    Clinical rheumatology, 2014, Volume: 33, Issue:2

    Topics: Adalimumab; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Dap

2014
Hypergammaglobulinemic purpura of Waldenstrom associated with systemic lupus erythematosus: report of a case and review of the literature.
    Lupus, 1995, Volume: 4, Issue:1

    Topics: Adult; Colchicine; Female; gamma-Globulins; Humans; Hydroxychloroquine; Immunoglobulin G; Immunoglob

1995
Management of rheumatoid arthritis.
    Disease-a-month : DM, 1986, Volume: 32, Issue:1

    Topics: Anti-Inflammatory Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Azathioprine; Chloroquine; Cyc

1986

Other Studies

23 other studies available for hydroxychloroquine and Vasculitis

ArticleYear
Exploring the risk factors for ischemic cerebrovascular disease in systemic lupus erythematosus: A single-center case-control study.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Aged; Antibodies, Anticardiolipin; Antibodies, Antiphospholipid; Carotid Artery Diseases; Case-Contr

2022
A case report of hypocomplementemic urticarial vasculitis presenting with membranoproliferative glomerulonephritis.
    BMC nephrology, 2020, 08-18, Volume: 21, Issue:1

    Topics: Aged; Antirheumatic Agents; Arthritis; Chronic Urticaria; Complement System Proteins; Cyclophosphami

2020
COVID-19 and rheumatic musculoskeletal disease patients: infection rates, attitudes and medication adherence in an Irish population.
    Rheumatology (Oxford, England), 2021, 02-01, Volume: 60, Issue:2

    Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Attitude to Health; Biological Products; Chloroq

2021
Rapid response to combination of hydroxychloroquine and prednisolone in a patient with refractory hypocomplementemic urticarial vasculitis.
    Dermatologic therapy, 2020, Volume: 33, Issue:6

    Topics: Humans; Hydroxychloroquine; Prednisolone; Urticaria; Vasculitis

2020
[Hypocomplementemic urticarial vasculitis].
    La Revue de medecine interne, 2018, Volume: 39, Issue:2

    Topics: Colchicine; Complement C1q; Female; Glucocorticoids; Humans; Hydroxychloroquine; Immunosuppressive A

2018
Acute pulmonary embolism in a child with ANCA-negative Idiopathic Pulmonary Capillaritis.
    Saudi medical journal, 2019, Volume: 40, Issue:6

    Topics: Acute Disease; Antibodies, Antineutrophil Cytoplasmic; Capillaries; Chest Pain; Child; Female; Hemor

2019
A rare case of laparoscopy towards SLE with lupus mesenteric vasculitis induced ascites.
    BMC surgery, 2019, Jul-02, Volume: 19, Issue:1

    Topics: Abdomen, Acute; Administration, Intravenous; Administration, Oral; Antirheumatic Agents; Ascites; Fe

2019
The clinical spectrum and therapeutic management of hypocomplementemic urticarial vasculitis: data from a French nationwide study of fifty-seven patients.
    Arthritis & rheumatology (Hoboken, N.J.), 2015, Volume: 67, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Colchicine; Comorbidity; Complement C1q; Female; France;

2015
Chronic alveolar haemorrhage in a paediatric patient: a diagnostic and treatment challenge.
    BMJ case reports, 2015, Apr-21, Volume: 2015

    Topics: Adolescent; Adrenal Cortex Hormones; Antibodies, Antineutrophil Cytoplasmic; Azathioprine; Biopsy; C

2015
Beneficial effect of hydroxychloroquine on cutaneous vasculitis in a Japanese patient with systemic lupus erythematosus.
    The Journal of dermatology, 2017, Volume: 44, Issue:4

    Topics: Adult; Antirheumatic Agents; Female; Humans; Hydroxychloroquine; Lupus Erythematosus, Cutaneous; Lup

2017
End-stage renal disease in patients with rheumatoid arthritis.
    Seminars in arthritis and rheumatism, 2017, Volume: 46, Issue:4

    Topics: Adalimumab; Adolescent; Adult; Amyloidosis; Antirheumatic Agents; Arthritis, Rheumatoid; Biological

2017
Systemic vasculitis developing after hydroxychloroquine interruption in a patient with Sjögren's syndrome.
    Clinical and experimental dermatology, 2010, Volume: 35, Issue:4

    Topics: Drug Administration Schedule; Female; Humans; Hydroxychloroquine; Lymphoma, B-Cell, Marginal Zone; M

2010
Large leg ulcers due to autoimmune diseases.
    Medical science monitor : international medical journal of experimental and clinical research, 2011, Volume: 17, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Autoimmune Diseases; Azathioprine; Ciprofloxacin; Cyclophosphamide;

2011
A case of primary Sjögren's syndrome presenting primarily with central nervous system vasculitic involvement.
    Rheumatology international, 2012, Volume: 32, Issue:3

    Topics: Adult; Angiography, Digital Subtraction; Azathioprine; Brain; Central Nervous System Diseases; Diagn

2012
Intestinal vasculitis and renal infarction in a lupus patient with antiphospholipid syndrome.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2012, Volume: 18, Issue:7

    Topics: Adolescent; Antiphospholipid Syndrome; Comorbidity; Drug Therapy, Combination; Female; Humans; Hydro

2012
[Classification of dermatologic manifestations in lupus erythematosus].
    Annales de medecine interne, 2003, Volume: 154, Issue:1

    Topics: Acitretin; Adrenal Cortex Hormones; Adult; Antimalarials; Clinical Trials as Topic; Dapsone; Dermato

2003
PENILE NODULES AS A MAJOR MANIFESTATION OF SUBACUTE ANGIITIS.
    Archives of internal medicine, 1964, Volume: 114

    Topics: Humans; Hydroxychloroquine; Infectious Mononucleosis; Male; Neuritis; Pathology; Penis; Prednisone;

1964
Multifocal electroretinographic changes in patients receiving hydroxychloroquine therapy.
    American journal of ophthalmology, 2005, Volume: 140, Issue:5

    Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Electroretinography; Female; Humans; Hydroxychlo

2005
Cutaneous lesions of the digits in systemic lupus erythematosus: 50 cases.
    Lupus, 2007, Volume: 16, Issue:3

    Topics: Administration, Oral; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Chilblains; Child; Cohort St

2007
The hypocomplementemic urticarial-vasculitis syndrome: therapeutic response to hydroxychloroquine.
    The Journal of allergy and clinical immunology, 1984, Volume: 73, Issue:5 Pt 1

    Topics: Adult; Biopsy; Complement Activating Enzymes; Complement C1q; Hemolytic Plaque Technique; Humans; Hy

1984
Corticosteroid-sparing strategies in the treatment of retinal vasculitis in systemic lupus erythematosus.
    Retina (Philadelphia, Pa.), 1995, Volume: 15, Issue:3

    Topics: Adolescent; Adult; Anti-Inflammatory Agents; Cohort Studies; Drug Therapy, Combination; Female; Foll

1995
Accelerated nodulosis and systemic manifestations during methotrexate therapy for rheumatoid arthritis.
    The European journal of medicine, 1993, Volume: 2, Issue:3

    Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Drug Therapy, Combination; Female; Humans; Hydroxych

1993
Nonvasculitic neuritis.
    Neurology, 1994, Volume: 44, Issue:1

    Topics: Aged; Female; Humans; Hydroxychloroquine; Neuritis; Prednisone; Vasculitis

1994