hydroxychloroquine has been researched along with Urinary Bladder Neoplasms in 2 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Urinary Bladder Neoplasms: Tumors or cancer of the URINARY BLADDER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "As human bladder cancer tumor exhibits high basal level of autophagic activities, we detected the autophagic flux in cells treated with CQ and HCQ, showing an alternation in LC3 flux in CQ- or HCQ-treated cells." | 5.46 | Chloroquine and hydroxychloroquine inhibit bladder cancer cell growth by targeting basal autophagy and enhancing apoptosis. ( Chen, HE; Chou, KY; Hwang, TI; Lin, JF; Lin, YC; Tsai, TF; Wen, SI; Yang, SC, 2017) |
| "As human bladder cancer tumor exhibits high basal level of autophagic activities, we detected the autophagic flux in cells treated with CQ and HCQ, showing an alternation in LC3 flux in CQ- or HCQ-treated cells." | 1.46 | Chloroquine and hydroxychloroquine inhibit bladder cancer cell growth by targeting basal autophagy and enhancing apoptosis. ( Chen, HE; Chou, KY; Hwang, TI; Lin, JF; Lin, YC; Tsai, TF; Wen, SI; Yang, SC, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chou, KY | 2 |
| Chen, PC | 1 |
| Chang, AC | 1 |
| Tsai, TF | 2 |
| Chen, HE | 2 |
| Ho, CY | 1 |
| Hwang, TI | 2 |
| Lin, YC | 1 |
| Lin, JF | 1 |
| Wen, SI | 1 |
| Yang, SC | 1 |
2 other studies available for hydroxychloroquine and Urinary Bladder Neoplasms
| Article | Year |
|---|---|
Attenuation of chloroquine and hydroxychloroquine on the invasive potential of bladder cancer through targeting matrix metalloproteinase 2 expression.
Topics: Autophagy; Chloroquine; Humans; Hydroxychloroquine; Male; Matrix Metalloproteinase 2; Urinary Bladde | 2021 |
Chloroquine and hydroxychloroquine inhibit bladder cancer cell growth by targeting basal autophagy and enhancing apoptosis.
Topics: Apoptosis; Autophagy; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chloroquine; DNA Fragment | 2017 |