hydroxychloroquine has been researched along with Ureteral Obstruction in 1 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Ureteral Obstruction: Blockage in any part of the URETER causing obstruction of urine flow from the kidney to the URINARY BLADDER. The obstruction may be congenital, acquired, unilateral, bilateral, complete, partial, acute, or chronic. Depending on the degree and duration of the obstruction, clinical features vary greatly such as HYDRONEPHROSIS and obstructive nephropathy.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydroxychloroquine (HCQ) has been adapted for the treatment of autoimmune diseases; however, the potential mechanism underlying the role of HCQ in renal fibrosis remains unclear." | 5.72 | Hydroxychloroquine alleviates renal interstitial fibrosis by inhibiting the PI3K/Akt signaling pathway. ( Bai, F; Fan, J; Feng, F; Li, D; Liu, L; Sun, N; Yang, H; Yang, X; Yu, K; Zhang, Y, 2022) |
| "Hydroxychloroquine (HCQ) has been adapted for the treatment of autoimmune diseases; however, the potential mechanism underlying the role of HCQ in renal fibrosis remains unclear." | 1.72 | Hydroxychloroquine alleviates renal interstitial fibrosis by inhibiting the PI3K/Akt signaling pathway. ( Bai, F; Fan, J; Feng, F; Li, D; Liu, L; Sun, N; Yang, H; Yang, X; Yu, K; Zhang, Y, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, D | 1 |
| Yu, K | 1 |
| Feng, F | 1 |
| Zhang, Y | 2 |
| Bai, F | 1 |
| Sun, N | 1 |
| Fan, J | 1 |
| Liu, L | 1 |
| Yang, H | 1 |
| Yang, X | 1 |
1 other study available for hydroxychloroquine and Ureteral Obstruction
| Article | Year |
|---|---|
Hydroxychloroquine alleviates renal interstitial fibrosis by inhibiting the PI3K/Akt signaling pathway.
Topics: Animals; Epithelial-Mesenchymal Transition; Female; Fibrosis; Humans; Hydroxychloroquine; Kidney; Ma | 2022 |