hydroxychloroquine has been researched along with Thrombotic Microangiopathies in 2 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Thrombotic Microangiopathies: Diseases that result in THROMBOSIS in MICROVASCULATURE. The two most prominent diseases are PURPURA, THROMBOTIC THROMBOCYTOPENIC; and HEMOLYTIC-UREMIC SYNDROME. Multiple etiological factors include VASCULAR ENDOTHELIAL CELL damage due to SHIGA TOXIN; FACTOR H deficiency; and aberrant VON WILLEBRAND FACTOR formation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Systemic lupus erythematosus is one of the diseases, which can be associated with thrombotic microangiopathy." | 1.39 | Auricular chondritis and thrombotic microangiopathy: an unusual combination revealing systemic lupus erythematosus. ( Anguel, N; Bellon, N; Goujard, C; Lambotte, O; Vandendries, C, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hasbal, NB | 1 |
| Bellon, N | 1 |
| Anguel, N | 1 |
| Vandendries, C | 1 |
| Goujard, C | 1 |
| Lambotte, O | 1 |
2 other studies available for hydroxychloroquine and Thrombotic Microangiopathies
| Article | Year |
|---|---|
Thrombotic microangiopathy: COVID-19 or hydroxychloroquine?
Topics: COVID-19; Humans; Hydroxychloroquine; Pandemics; SARS-CoV-2; Thrombotic Microangiopathies | 2020 |
Auricular chondritis and thrombotic microangiopathy: an unusual combination revealing systemic lupus erythematosus.
Topics: Adrenal Cortex Hormones; Adult; Cartilage Diseases; Comorbidity; Drug Therapy, Combination; Ear Cart | 2013 |