Page last updated: 2024-10-28

hydroxychloroquine and Thrombosis

hydroxychloroquine has been researched along with Thrombosis in 66 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Thrombosis: Formation and development of a thrombus or blood clot in the blood vessel.

Research Excerpts

ExcerptRelevanceReference
"Sporadic studies suggest hydroxychloroquine (HCQ) may be effective for thrombosis prevention in patients with primary antiphospholipid syndrome (PAPS) and may lead to antiphospholipid antibody (aPL) titer reduction but data from randomized studies are lacking."9.34The effect of hydroxychloroquine on thrombosis prevention and antiphospholipid antibody levels in primary antiphospholipid syndrome: A pilot open label randomized prospective study. ( Koutsogianni, A; Kravvariti, E; Samoli, E; Sfikakis, PP; Tektonidou, MG, 2020)
"Objective The objective of this study was to determine the efficacy of hydroxychloroquine (HCQ) in the primary thrombosis prevention of antiphospholipid antibody (aPL)-positive patients with no other systemic autoimmune diseases."9.27Hydroxychloroquine in the primary thrombosis prophylaxis of antiphospholipid antibody positive patients without systemic autoimmune disease. ( Belmont, HM; Branch, DW; Cuadrado, MJ; Erkan, D; Gonzalez, E; Knight, JS; Sciascia, S; Tektonidou, MG; Unlu, O; Uthman, I; Wahl, D; Willis, R; Zhang, Z; Zuily, S, 2018)
"The use of low-dose aspirin and heparinoids has improved the pregnancy outcome in obstetric antiphospholipid syndrome (APS)."8.93The efficacy of hydroxychloroquine in altering pregnancy outcome in women with antiphospholipid antibodies. Evidence and clinical judgment. ( Branch, DW; Hunt, BJ; Khamashta, M; Levy, RA; Middeldorp, S; Pavord, S; Roccatello, D; Ruiz-Irastorza, G; Schreiber, K; Sciascia, S; Tincani, A, 2016)
"Hydroxychloroquine (HCQ) has a primary role in the prophylaxis and treatment of systemic lupus erythematosus (SLE) and may be protective against thrombosis in SLE."8.02Association of Higher Hydroxychloroquine Blood Levels With Reduced Thrombosis Risk in Systemic Lupus Erythematosus. ( Goldman, DW; Konig, MF; Li, J; Petri, M, 2021)
"Studies have shown a protective effect of hydroxychloroquine on thrombosis in systemic lupus erythematosus patients."7.76[Hydroxychloroquine: a new therapeutic approach to the thrombotic manifestations of antiphospholipid syndrome]. ( Ankri, A; Darnige, L; Fischer, AM; Szymezak, J, 2010)
"Preeclampsia, gestational hypertension, and prematurity were significantly lower in the HCQ+ group than in the HCQ- group (OR 0."6.72Hydroxychloroquine prophylaxis for preeclampsia, hypertension and prematurity in pregnant patients with systemic lupus erythematosus: A meta-analysis. ( Duan, J; Gao, J; Guo, Q; Ma, D; Wen, X; Xu, K; Zhang, G; Zhang, L, 2021)
"Hydroxychloroquine also has known benefits in reducing some traditional cardiovascular risk factors, such as hyperlipidemia and diabetes mellitus."6.47Use of hydroxychloroquine to prevent thrombosis in systemic lupus erythematosus and in antiphospholipid antibody-positive patients. ( Petri, M, 2011)
"Thrombosis was assessed both in vitro by measuring thrombin generation time (TGT) and tissue factor (TF) expression and in vivo by the measurement of the time to occlusion in carotid and the total thrombosis area in mesenteric arteries."5.51Hydroxychloroquine reverses the prothrombotic state in a mouse model of antiphospholipid syndrome: Role of reduced inflammation and endothelial dysfunction. ( Benhamou, Y; Billoir, P; Damian, L; Galas, L; Joannides, R; Jouen, F; Le Besnerais, M; Le Cam-Duchez, V; Levesque, H; Miranda, S; Richard, V; Schapman, D; Thiebaut, PA, 2019)
"Antiphospholipid syndrome is associated with endothelial dysfunction, which leads to thrombosis and early atheroma."5.48Hydroxychloroquine partially prevents endothelial dysfunction induced by anti-beta-2-GPI antibodies in an in vivo mouse model of antiphospholipid syndrome. ( Begorre, MA; Belizna, C; Caillon, A; Henrion, D; Kauffenstein, G; Loufrani, L; Poli, C; Urbanski, G, 2018)
"Sporadic studies suggest hydroxychloroquine (HCQ) may be effective for thrombosis prevention in patients with primary antiphospholipid syndrome (PAPS) and may lead to antiphospholipid antibody (aPL) titer reduction but data from randomized studies are lacking."5.34The effect of hydroxychloroquine on thrombosis prevention and antiphospholipid antibody levels in primary antiphospholipid syndrome: A pilot open label randomized prospective study. ( Koutsogianni, A; Kravvariti, E; Samoli, E; Sfikakis, PP; Tektonidou, MG, 2020)
"Objective The objective of this study was to determine the efficacy of hydroxychloroquine (HCQ) in the primary thrombosis prevention of antiphospholipid antibody (aPL)-positive patients with no other systemic autoimmune diseases."5.27Hydroxychloroquine in the primary thrombosis prophylaxis of antiphospholipid antibody positive patients without systemic autoimmune disease. ( Belmont, HM; Branch, DW; Cuadrado, MJ; Erkan, D; Gonzalez, E; Knight, JS; Sciascia, S; Tektonidou, MG; Unlu, O; Uthman, I; Wahl, D; Willis, R; Zhang, Z; Zuily, S, 2018)
" Seventy-four patients about to undergo primary unilateral total hip arthroplasty for osteoarthrosis, all receiving a standard thrombosis prophylaxis regime of thigh-length anti-embolic stockings, 5,000 IU heparin delivered subcutaneously twice daily, and 400 mg hydroxychloroquine sulfate delivered twice daily, were entered in a prospective trial."5.07The effectiveness of intermittent plantar venous compression in prevention of deep venous thrombosis after total hip arthroplasty. ( Bradley, JG; Jager, HJ; Krugener, GH, 1993)
"The use of low-dose aspirin and heparinoids has improved the pregnancy outcome in obstetric antiphospholipid syndrome (APS)."4.93The efficacy of hydroxychloroquine in altering pregnancy outcome in women with antiphospholipid antibodies. Evidence and clinical judgment. ( Branch, DW; Hunt, BJ; Khamashta, M; Levy, RA; Middeldorp, S; Pavord, S; Roccatello, D; Ruiz-Irastorza, G; Schreiber, K; Sciascia, S; Tincani, A, 2016)
" Through the dedication and hard work of 50 APS ACTION members, collaborative international projects are currently underway including a multicenter web-based registry and repository of aPL-positive patients, a randomized controlled clinical trial assessing the efficacy of hydroxychloroquine for primary thrombosis prevention in persistently aPL-positive but thrombosis-free patients, standardization of aPL testing through the use of core laboratories worldwide, identification of the limitations in the existing aPL/APS literature, and conducting observational research studies to further our understanding of the disease."4.93AntiPhospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking (APS ACTION): 5-Year Update. ( Andrade, D; Barbhaiya, M; Erkan, D, 2016)
"Hydroxychloroquine (HCQ) has a primary role in the prophylaxis and treatment of systemic lupus erythematosus (SLE) and may be protective against thrombosis in SLE."4.02Association of Higher Hydroxychloroquine Blood Levels With Reduced Thrombosis Risk in Systemic Lupus Erythematosus. ( Goldman, DW; Konig, MF; Li, J; Petri, M, 2021)
"Studies have shown a protective effect of hydroxychloroquine on thrombosis in systemic lupus erythematosus patients."3.76[Hydroxychloroquine: a new therapeutic approach to the thrombotic manifestations of antiphospholipid syndrome]. ( Ankri, A; Darnige, L; Fischer, AM; Szymezak, J, 2010)
"Aspirin has been shown to reduce the number of transient ischemic attacks (TIA), stroke and death in patients with multiple TIA."3.75Antithrombotic effects of drugs which suppress platelet function: their potential in prevention growth of tumour cells. ( Turpie, AG, 1982)
"Three groups of nine mice were injected with purified immunoglobulin G (IgG) from a patient with the antiphospholipid syndrome (IgG-APS) and then fed with hydroxychloroquine at various doses (100, 6, and 3 mg/kg body wt)."3.69Hydroxychloroquine reverses thrombogenic properties of antiphospholipid antibodies in mice. ( Anderson, G; Barker, JH; Edwards, MH; Harris, EN; Liu, X; Pierangeli, S, 1997)
" However, should some hospitalized patients have dosage escalation to intermediate dose? Should some be considered for full-dose anticoagulation without a measurable thromboembolic event and how should that anticoagulation be monitored? Should patients receive postdischarge anticoagulation and with what medication and for how long? What thrombotic issues are related to the various medications being used to treat this coagulopathy? Is antiphospholipid antibody part of this syndrome? What is the significance of isolated ischemic stroke and limb ischemia in this disorder and how does this interface with the rest of the clinical and laboratory features of this disorder? The aims of this article are to explore these questions and interpret the available data based on the current evidence."2.72COVID-19 and Its Implications for Thrombosis and Anticoagulation. ( Berkman, SA; Tapson, VF, 2021)
"Preeclampsia, gestational hypertension, and prematurity were significantly lower in the HCQ+ group than in the HCQ- group (OR 0."2.72Hydroxychloroquine prophylaxis for preeclampsia, hypertension and prematurity in pregnant patients with systemic lupus erythematosus: A meta-analysis. ( Duan, J; Gao, J; Guo, Q; Ma, D; Wen, X; Xu, K; Zhang, G; Zhang, L, 2021)
"The pandemic outbreak of coronavirus disease 2019 (COVID-19) is rapidly spreading all over the world."2.66The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China. ( Li, T; Liu, Z; Qin, Y; Wang, J; Wang, Q; Yan, X; Zeng, X; Zhang, F; Zhang, S; Zhang, W; Zhang, X; Zhao, Y, 2020)
"Management of thrombosis is based on long-term oral anticoagulation and patients with arterial events should be treated aggressively."2.53Current status and future prospects for the treatment of antiphospholipid syndrome. ( Al Marzooqi, A; Al Saleh, J; Khamashta, M; Leone, A, 2016)
"Atherothrombosis is no longer considered solely a disorder of lipoprotein accumulation in the arterial wall."2.50Anti-inflammatory therapies for cardiovascular disease. ( Lüscher, TF; Ridker, PM, 2014)
"Hydroxychloroquine also has known benefits in reducing some traditional cardiovascular risk factors, such as hyperlipidemia and diabetes mellitus."2.47Use of hydroxychloroquine to prevent thrombosis in systemic lupus erythematosus and in antiphospholipid antibody-positive patients. ( Petri, M, 2011)
"Hydroxychloroquine has also been shown to reduce in vivo aPL-induced thrombus formation."2.42Intracellular signaling triggered by antiphospholipid antibodies in platelets and endothelial cells: a pathway to targeted therapies. ( Harris, EN; Pierangeli, SS; Vega-Ostertag, M, 2004)
"Catastrophic antiphospholipid antibody syndrome (CAPS) is an accelerated form of disease with rapid involvement of multiple organ systems often posing a diagnostic challenge."1.72Catastrophic Anti-Phospholipid Syndrome in Systemic Lupus Erythematosus: A Tsunami in the Ocean. ( Asturkar, V; Bhanu, K; Dorji, T; Hegde, A; Yangzom, S, 2022)
"After two months, a systemic lupus erythematosus was diagnosed."1.62Pediatric catastrophic antiphospholipid syndrome patient evolving to systemic lupus erythematosus. ( Carvalho, JF; Shoenfeld, Y; Silva, FF, 2021)
"Thrombosis was assessed both in vitro by measuring thrombin generation time (TGT) and tissue factor (TF) expression and in vivo by the measurement of the time to occlusion in carotid and the total thrombosis area in mesenteric arteries."1.51Hydroxychloroquine reverses the prothrombotic state in a mouse model of antiphospholipid syndrome: Role of reduced inflammation and endothelial dysfunction. ( Benhamou, Y; Billoir, P; Damian, L; Galas, L; Joannides, R; Jouen, F; Le Besnerais, M; Le Cam-Duchez, V; Levesque, H; Miranda, S; Richard, V; Schapman, D; Thiebaut, PA, 2019)
"Hydroxychloroquine was found to be linked to a significantly higher live birth rate with respect to the other oral treatments in the Group II patients."1.48Effect of Additional Treatments Combined with Conventional Therapies in Pregnant Patients with High-Risk Antiphospholipid Syndrome: A Multicentre Study. ( Alijotas-Reig, J; Andreoli, L; Bertero, MT; Costedoat-Chalumeau, N; Cuadrado, MJ; De Carolis, S; Gerosa, M; Grandone, E; Haladyj, E; Hoxha, A; Khamashta, MA; Latino, JO; Maina, A; Marozio, L; Mayer-Pickel, K; Mekinian, A; Meroni, PL; Morel, N; Pengo, V; Ramoni, V; Reshetnyak, T; Ruffatti, A; Sciascia, S; Serrano, F; Simchen, MJ; Tenti, S; Tincani, A; Tonello, M; Udry, S, 2018)
"Antiphospholipid syndrome is associated with endothelial dysfunction, which leads to thrombosis and early atheroma."1.48Hydroxychloroquine partially prevents endothelial dysfunction induced by anti-beta-2-GPI antibodies in an in vivo mouse model of antiphospholipid syndrome. ( Begorre, MA; Belizna, C; Caillon, A; Henrion, D; Kauffenstein, G; Loufrani, L; Poli, C; Urbanski, G, 2018)
"Few studies have examined thrombosis in systemic lupus erythematosus (SLE), none have included Asian-Americans, and most have had small sample sizes."1.35Risk and protective factors for thrombosis in systemic lupus erythematosus: results from a large, multi-ethnic cohort. ( Cleveland, CM; Criswell, LA; Kaiser, R, 2009)
"and sulfinpyrazone have been tested in several large scale clinical trials."1.26[Antiplatelet drugs (author's transl)]. ( Dechavanne, M; Follea, G; Trzeciak, MC, 1979)

Research

Studies (66)

TimeframeStudies, this research(%)All Research%
pre-199012 (18.18)18.7374
1990's3 (4.55)18.2507
2000's5 (7.58)29.6817
2010's25 (37.88)24.3611
2020's21 (31.82)2.80

Authors

AuthorsStudies
Mendoza-Pinto, C1
García-Carrasco, M1
Munguía Realpozo, P1
Méndez-Martínez, S1
Hussain, H1
Tarantino, MD1
Chaturvedi, S3
McCrae, KR4
Roberts, JC1
Dorji, T1
Hegde, A1
Asturkar, V1
Yangzom, S1
Bhanu, K1
Hubben, A1
Arachchillage, DJ1
Laffan, M2
Pericleous, C1
Kravvariti, E1
Koutsogianni, A1
Samoli, E1
Sfikakis, PP1
Tektonidou, MG5
Zhang, W1
Zhao, Y1
Zhang, F1
Wang, Q1
Li, T1
Liu, Z1
Wang, J1
Qin, Y1
Zhang, X1
Yan, X1
Zeng, X1
Zhang, S1
Doms, J1
Horisberger, A1
Ribi, C1
Besutti, G1
Bonacini, R1
Iotti, V1
Marini, G1
Riva, N1
Dolci, G1
Maiorana, M1
Spaggiari, L1
Monelli, F1
Ligabue, G1
Guaraldi, G1
Rossi, PG1
Pattacini, P1
Massari, M1
Sciascia, S5
Schreiber, K2
Radin, M2
Roccatello, D3
Krämer, BK1
Stach, K1
Hossri, S1
Shadi, M1
Hamarsha, Z1
Schneider, R1
El-Sayegh, D1
González-García, A1
López-Rodríguez, M1
Redondo, S1
Patier, JL1
Masso, P1
Tenorio, M1
Fajardo, GS1
Sarhane, Y1
Lacalzada, MM1
Manzano, L1
Di Perri, G1
Meng, J1
Chen, L1
Hou, J1
Chi, H1
Wang, Z1
Yang, C1
Su, Y1
Carvalho, JF1
Silva, FF1
Shoenfeld, Y1
Cohen, H2
Cuadrado, MJ4
Erkan, D4
Duarte-Garcia, A1
Isenberg, DA1
Knight, JS2
Ortel, TL2
Rahman, A2
Salmon, JE2
Williams, DJ1
Willis, R3
Woller, SC1
Andrade, D4
Petri, M3
Konig, MF1
Li, J1
Goldman, DW1
Devaux, CA1
Camoin-Jau, L1
Mege, JL1
Raoult, D1
Berkman, SA1
Tapson, VF1
Duan, J1
Ma, D1
Wen, X1
Guo, Q1
Gao, J1
Zhang, G1
Xu, K1
Zhang, L1
Anedda, L1
Bianchini, L1
Cuzzolin, L1
Finco, G1
Fanos, V1
Marcialis, MA1
Arachchillage, DRJ1
Unlu, O1
Belmont, HM1
Branch, DW2
Gonzalez, E1
Uthman, I2
Zhang, Z1
Wahl, D1
Zuily, S1
Ruffatti, A2
Tonello, M1
Hoxha, A1
Latino, JO2
Udry, S2
Reshetnyak, T1
Costedoat-Chalumeau, N1
Morel, N1
Marozio, L1
Tincani, A3
Andreoli, L2
Haladyj, E1
Meroni, PL2
Gerosa, M1
Alijotas-Reig, J2
Tenti, S1
Mayer-Pickel, K1
Simchen, MJ1
Bertero, MT1
De Carolis, S1
Ramoni, V1
Mekinian, A1
Grandone, E1
Maina, A1
Serrano, F1
Pengo, V1
Khamashta, MA2
Belizna, C4
Pregnolato, F1
Abad, S1
Amital, H1
Amoura, Z1
Andres, E1
Aouba, A1
Apras Bilgen, S1
Arnaud, L1
Bienvenu, B1
Bitsadze, V1
Blanco, P1
Blank, M1
Borghi, MO1
Caligaro, A1
Candrea, E1
Canti, V1
Chiche, L1
Chretien, JM1
Cohen Tervaert, JW1
Damian, L2
Delross, T1
Dernis, E1
Devreese, K1
Djokovic, A1
Esteve-Valverde, E1
Favaro, M1
Fassot, C1
Ferrer-Oliveras, R1
Godon, A1
Hamidou, M1
Hasan, M1
Henrion, D3
Imbert, B1
Jeandel, PY1
Jeannin, P1
Jego, P1
Jourde-Chiche, N1
Khizroeva, J1
Lambotte, O1
Landron, C1
Lazaro, E1
de Leeuw, K1
Le Gallou, T1
Kiliç, L1
Limper, M1
Loufrani, L3
Lubin, R1
Magy-Bertrand, N1
Mahe, G1
Makatsariya, A1
Martin, T1
Muchardt, C1
Nagy, G1
Omarjee, L1
Van Paasen, P1
Pernod, G1
Perrinet, F1
Pïres Rosa, G1
Pistorius, MA1
Said, F1
Saulnier, P1
Sene, D1
Sentilhes, L1
Shovman, O1
Sibilia, J1
Sinescu, C1
Stanisavljevic, N1
Stojanovich, L1
Tam, LS1
Tollis, F1
Ungeheuer, MN1
Versini, M1
Cervera, R1
Urbanski, G1
Caillon, A1
Poli, C1
Kauffenstein, G1
Begorre, MA1
Miranda, S1
Billoir, P1
Thiebaut, PA1
Schapman, D1
Le Besnerais, M1
Jouen, F1
Galas, L1
Levesque, H1
Le Cam-Duchez, V1
Joannides, R1
Richard, V1
Benhamou, Y1
Schmidt-Tanguy, A1
Voswinkel, J1
Subra, JF1
Rohmer, V1
Ifrah, N1
Ibáñez, S1
Iruretagoyena, M1
Gutiérrez, MA1
Aguiar, CL1
Danowski, A1
Levy, RA2
Lockshin, MD1
Mar, N1
Kosowicz, R1
Hook, K1
Ridker, PM1
Lüscher, TF1
Merashli, M1
Noureldine, MH1
Khamashta, M3
Middeldorp, S1
Pavord, S1
Ruiz-Irastorza, G1
Hunt, BJ1
Tektonidou, M1
Al Marzooqi, A1
Leone, A1
Al Saleh, J1
Barbhaiya, M1
Bazzan, M1
Kaiser, R1
Cleveland, CM1
Criswell, LA1
Laskari, K1
Panagiotakos, DB1
Moutsopoulos, HM1
Jung, H1
Bobba, R1
Su, J1
Shariati-Sarabi, Z1
Gladman, DD1
Urowitz, M1
Lou, W1
Fortin, PR1
Wallace, DJ1
Szymezak, J1
Ankri, A1
Fischer, AM1
Darnige, L1
Scoble, T1
Wijetilleka, S1
Francès, C1
Barete, S1
Ayoub, N1
Piette, JC1
BETETTO, D1
CRISTINA, P1
SPANIO, G1
Pierangeli, SS1
Vega-Ostertag, M1
Harris, EN2
Ho, KT1
Ahn, CW1
Alarcón, GS1
Baethge, BA1
Tan, FK1
Roseman, J1
Bastian, HM1
Fessler, BJ1
McGwin, G1
Vilá, LM1
Calvo-Alén, J1
Reveille, JD1
Hansen, MS1
Birgens, HS1
Turpie, AG2
Bradley, JG1
Krugener, GH1
Jager, HJ1
Edwards, MH1
Pierangeli, S1
Liu, X1
Barker, JH1
Anderson, G1
Hirsh, J4
Latour, JG1
Dechavanne, M1
Follea, G1
Trzeciak, MC1
Harker, LA2
Gent, M2
Genton, E2
Didisheim, P1
Kazmier, FJ1
Fuster, V1
Bounameaux, Y1
Jobin, F1
Gagnon, FT1

Clinical Trials (10)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Nutritional Habits, Does it Affect Coronavirus Disease 2019 (COVID-19) Infection Outcome? An Egyptian Experience[NCT04447144]200 participants (Anticipated)Observational2020-06-01Recruiting
Evaluation of Independent Clinical- Laboratory Predictors of Clinical Outcomes in Hospitalized Positive SARS-CoV2 Patients (Outcomes SARS-CoV2)[NCT05162534]1,800 participants (Actual)Observational2020-05-29Completed
Comparison of Cytokine Hemadsorption as an Immunomodulator Therapy in Covid 19 Patients With and Without Bacterial Sepsis[NCT04920851]23 participants (Anticipated)Observational2021-06-10Recruiting
Comparison of Clopidogrel-based Antiplatelet Therapy Versus Warfarin as Secondary Prevention Strategy for AntiPhospholipid Syndrome-related STROKE (APS-STROKE)[NCT05995600]Phase 4400 participants (Anticipated)Interventional2023-12-31Not yet recruiting
"Constitution d'Une Cohorte Prospective de Sujets Sains et Malades et d'Une Collection de Ressources Biologiques associées Pour l'étude du système Immunitaire et de Ses déterminants Génétiques et Environnementaux"[NCT03925272]2,200 participants (Anticipated)Interventional2011-02-02Recruiting
Collection d'échantillons Biologiques Humains de Sujets Sains et Malades Pour la Mise au Point et la Validation de Nouvelles méthodes de Diagnostic et Pour la réalisation d'Expertises Dans le Domaine Des Maladies Infectieuses et Tropicales[NCT03912246]800 participants (Actual)Interventional2009-04-27Completed
Perioperative Inflammatory Response Assessment in High-risk Patients Undergoing Noncardiac Surgery - a Prospective Non-interventional Observational Study[NCT04753307]1,400 participants (Anticipated)Observational2021-01-19Recruiting
The Comparison of Effect Between Salsalate and Placebo in Osteoarthritis With Nonalcoholic Fatty Liver Disease: Investigator Initiated Randomized Placebo-controlled Double-blind, Pilot Study[NCT03222206]Phase 434 participants (Actual)Interventional2017-11-08Completed
A Multicenter, Double-blind, Randomized and Parallel Controlled Study of Hydroxychloroquine Sulfate in the Treatment of Recurrent Miscarriage With Antiphospholipid Syndrome[NCT04624269]Phase 4384 participants (Anticipated)Interventional2020-12-01Not yet recruiting
[NCT00005436]0 participants Observational1991-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

36 reviews available for hydroxychloroquine and Thrombosis

ArticleYear
Therapeutic options for the management of severe COVID-19: A rheumatology perspective.
    Reumatologia clinica, 2021, Volume: 17, Issue:8

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Antiviral Agents; Chloroquine; Combined

2021
Emerging Therapies in Antiphospholipid Syndrome.
    Transfusion medicine reviews, 2022, Volume: 36, Issue:4

    Topics: Antibodies, Antiphospholipid; Anticoagulants; Antiphospholipid Syndrome; Female; Humans; Hydroxychlo

2022
Hydroxychloroquine as an Immunomodulatory and Antithrombotic Treatment in Antiphospholipid Syndrome.
    International journal of molecular sciences, 2023, Jan-10, Volume: 24, Issue:2

    Topics: Anticoagulants; Antimalarials; Antiphospholipid Syndrome; Female; Fibrinolytic Agents; Humans; Hydro

2023
The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China.
    Clinical immunology (Orlando, Fla.), 2020, Volume: 214

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Betacoronavirus; Chloroquine; Coronavir

2020
The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China.
    Clinical immunology (Orlando, Fla.), 2020, Volume: 214

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Betacoronavirus; Chloroquine; Coronavir

2020
The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China.
    Clinical immunology (Orlando, Fla.), 2020, Volume: 214

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Betacoronavirus; Chloroquine; Coronavir

2020
The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China.
    Clinical immunology (Orlando, Fla.), 2020, Volume: 214

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Betacoronavirus; Chloroquine; Coronavir

2020
The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China.
    Clinical immunology (Orlando, Fla.), 2020, Volume: 214

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Betacoronavirus; Chloroquine; Coronavir

2020
The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China.
    Clinical immunology (Orlando, Fla.), 2020, Volume: 214

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Betacoronavirus; Chloroquine; Coronavir

2020
The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China.
    Clinical immunology (Orlando, Fla.), 2020, Volume: 214

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Betacoronavirus; Chloroquine; Coronavir

2020
The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China.
    Clinical immunology (Orlando, Fla.), 2020, Volume: 214

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Betacoronavirus; Chloroquine; Coronavir

2020
The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China.
    Clinical immunology (Orlando, Fla.), 2020, Volume: 214

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Betacoronavirus; Chloroquine; Coronavir

2020
[Management of the antiphospholipid syndrome in adults].
    Revue medicale suisse, 2020, Apr-08, Volume: 16, Issue:689

    Topics: Adult; Antibodies, Antiphospholipid; Anticoagulants; Antiphospholipid Syndrome; Female; Humans; Hydr

2020
Aortitis in the setting of catastrophic antiphospholipid syndrome in a patient with systemic lupus erythematosus.
    Lupus, 2020, Volume: 29, Issue:9

    Topics: Adrenal Cortex Hormones; Antibodies, Antiphospholipid; Anticoagulants; Antiphospholipid Syndrome; Ao

2020
Probable catastrophic antiphospholipid syndrome secondary to chronic myelomonocytic leukaemia in an adult patient and a mini review.
    Lupus, 2020, Volume: 29, Issue:10

    Topics: Antiphospholipid Syndrome; Bone Marrow; Computed Tomography Angiography; Humans; Hydroxychloroquine;

2020
16th International Congress on Antiphospholipid Antibodies Task Force Report on Antiphospholipid Syndrome Treatment Trends.
    Lupus, 2020, Volume: 29, Issue:12

    Topics: Antibodies, Antiphospholipid; Anticoagulants; Antiphospholipid Syndrome; Congresses as Topic; Factor

2020
Can hydroxychloroquine be protective against COVID-19-associated thrombotic events ?
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2021, Volume: 54, Issue:1

    Topics: Antibodies, Antiphospholipid; Antiphospholipid Syndrome; COVID-19; COVID-19 Drug Treatment; Humans;

2021
COVID-19 and Its Implications for Thrombosis and Anticoagulation.
    Seminars in respiratory and critical care medicine, 2021, Volume: 42, Issue:2

    Topics: Adenosine Monophosphate; Alanine; Ambulatory Care; Antibodies, Antiphospholipid; Antibodies, Monoclo

2021
Hydroxychloroquine prophylaxis for preeclampsia, hypertension and prematurity in pregnant patients with systemic lupus erythematosus: A meta-analysis.
    Lupus, 2021, Volume: 30, Issue:7

    Topics: Abortion, Spontaneous; Antirheumatic Agents; Case-Control Studies; Diabetes, Gestational; Female; HE

2021
What if COVID-19 affects the child: which weapons and how to use them.
    European review for medical and pharmacological sciences, 2021, Volume: 25, Issue:8

    Topics: Adenosine Monophosphate; Adolescent; Age Factors; Alanine; Antibodies, Monoclonal, Humanized; Antico

2021
Pathogenesis and management of antiphospholipid syndrome.
    British journal of haematology, 2017, Volume: 178, Issue:2

    Topics: Anticoagulants; Antiphospholipid Syndrome; Autoantibodies; beta 2-Glycoprotein I; Complement Inactiv

2017
Diagnosis and management of the antiphospholipid syndrome.
    Blood reviews, 2017, Volume: 31, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Anticoagulants; Antiphospholipid Syndrome; Disease Management; En

2017
HIBISCUS: Hydroxychloroquine for the secondary prevention of thrombotic and obstetrical events in primary antiphospholipid syndrome.
    Autoimmunity reviews, 2018, Volume: 17, Issue:12

    Topics: Antiphospholipid Syndrome; Delivery, Obstetric; Female; Humans; Hydroxychloroquine; Pregnancy; Pregn

2018
HIBISCUS: Hydroxychloroquine for the secondary prevention of thrombotic and obstetrical events in primary antiphospholipid syndrome.
    Autoimmunity reviews, 2018, Volume: 17, Issue:12

    Topics: Antiphospholipid Syndrome; Delivery, Obstetric; Female; Humans; Hydroxychloroquine; Pregnancy; Pregn

2018
HIBISCUS: Hydroxychloroquine for the secondary prevention of thrombotic and obstetrical events in primary antiphospholipid syndrome.
    Autoimmunity reviews, 2018, Volume: 17, Issue:12

    Topics: Antiphospholipid Syndrome; Delivery, Obstetric; Female; Humans; Hydroxychloroquine; Pregnancy; Pregn

2018
HIBISCUS: Hydroxychloroquine for the secondary prevention of thrombotic and obstetrical events in primary antiphospholipid syndrome.
    Autoimmunity reviews, 2018, Volume: 17, Issue:12

    Topics: Antiphospholipid Syndrome; Delivery, Obstetric; Female; Humans; Hydroxychloroquine; Pregnancy; Pregn

2018
[New alternatives for the treatment of antiphospholipid syndrome. A literature review].
    Revista medica de Chile, 2013, Volume: 141, Issue:8

    Topics: Agmatine; Antibodies, Monoclonal, Murine-Derived; Antiphospholipid Syndrome; Dipeptides; Glucocortic

2013
14th International Congress on Antiphospholipid Antibodies: task force report on antiphospholipid syndrome treatment trends.
    Autoimmunity reviews, 2014, Volume: 13, Issue:6

    Topics: Antibodies, Antiphospholipid; Anticoagulants; Antiphospholipid Syndrome; Factor Xa; Humans; Hydroxyc

2014
Anti-inflammatory therapies for cardiovascular disease.
    European heart journal, 2014, Jul-14, Volume: 35, Issue:27

    Topics: Adaptive Immunity; Anti-Inflammatory Agents; Antioxidants; Atherosclerosis; C-Reactive Protein; Carr

2014
Anti-inflammatory therapies for cardiovascular disease.
    European heart journal, 2014, Jul-14, Volume: 35, Issue:27

    Topics: Adaptive Immunity; Anti-Inflammatory Agents; Antioxidants; Atherosclerosis; C-Reactive Protein; Carr

2014
Anti-inflammatory therapies for cardiovascular disease.
    European heart journal, 2014, Jul-14, Volume: 35, Issue:27

    Topics: Adaptive Immunity; Anti-Inflammatory Agents; Antioxidants; Atherosclerosis; C-Reactive Protein; Carr

2014
Anti-inflammatory therapies for cardiovascular disease.
    European heart journal, 2014, Jul-14, Volume: 35, Issue:27

    Topics: Adaptive Immunity; Anti-Inflammatory Agents; Antioxidants; Atherosclerosis; C-Reactive Protein; Carr

2014
Hydroxychloroquine as an anti-thrombotic in antiphospholipid syndrome.
    Autoimmunity reviews, 2015, Volume: 14, Issue:4

    Topics: Animals; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Blood Platelets; Erythrocytes; Hum

2015
Antiphospholipid syndrome: an update.
    European journal of clinical investigation, 2015, Volume: 45, Issue:6

    Topics: Adrenal Cortex Hormones; Animals; Annexin A2; Anticoagulants; Antiphospholipid Syndrome; Drugs, Inve

2015
The efficacy of hydroxychloroquine in altering pregnancy outcome in women with antiphospholipid antibodies. Evidence and clinical judgment.
    Thrombosis and haemostasis, 2016, Volume: 115, Issue:2

    Topics: Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Aspirin; Cohort Studies; Female; Heparin; H

2016
The antiphospholipid syndrome: still an enigma.
    Hematology. American Society of Hematology. Education Program, 2015, Volume: 2015

    Topics: Administration, Oral; Antibodies, Antiphospholipid; Anticoagulants; Antiphospholipid Syndrome; beta

2015
Emerging Therapies in Antiphospholipid Syndrome.
    Current rheumatology reports, 2016, Volume: 18, Issue:4

    Topics: Animals; Anticoagulants; Antiphospholipid Syndrome; Complement Inactivating Agents; Disease Models,

2016
Current status and future prospects for the treatment of antiphospholipid syndrome.
    Expert review of clinical immunology, 2016, Volume: 12, Issue:9

    Topics: Animals; Anticoagulants; Antiphospholipid Syndrome; Autoantibodies; Female; Humans; Hydroxychloroqui

2016
AntiPhospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking (APS ACTION): 5-Year Update.
    Current rheumatology reports, 2016, Volume: 18, Issue:10

    Topics: Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Antirheumatic Agents; Clinical Trials as To

2016
Novel diagnostic and therapeutic frontiers in thrombotic anti-phospholipid syndrome.
    Internal and emergency medicine, 2017, Volume: 12, Issue:1

    Topics: Adult; Antibodies, Anticardiolipin; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antic

2017
Use of hydroxychloroquine to prevent thrombosis in systemic lupus erythematosus and in antiphospholipid antibody-positive patients.
    Current rheumatology reports, 2011, Volume: 13, Issue:1

    Topics: Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Enzyme Inhibitors; Humans; Hydroxychloroqui

2011
Management of refractory anti-phospholipid syndrome.
    Autoimmunity reviews, 2011, Volume: 10, Issue:11

    Topics: Antibodies, Monoclonal, Murine-Derived; Antiphospholipid Syndrome; Clinical Trials as Topic; Evidenc

2011
Intracellular signaling triggered by antiphospholipid antibodies in platelets and endothelial cells: a pathway to targeted therapies.
    Thrombosis research, 2004, Volume: 114, Issue:5-6

    Topics: Animals; Antibodies, Antiphospholipid; Antibodies, Monoclonal; Antiphospholipid Syndrome; Endotheliu

2004
Antithrombotic effects of drugs which suppress platelet function: their potential in prevention growth of tumour cells.
    Progress in clinical and biological research, 1982, Volume: 89

    Topics: Aspirin; Blood Platelets; Cardiovascular Diseases; Cell Division; Clinical Trials as Topic; Coronary

1982
Hydroxychloroquine use in the Baltimore Lupus Cohort: effects on lipids, glucose and thrombosis.
    Lupus, 1996, Volume: 5 Suppl 1

    Topics: Antirheumatic Agents; Baltimore; Blood Glucose; Cohort Studies; Diabetes Complications; Diabetes Mel

1996
Platelet suppressive therapy.
    British medical bulletin, 1978, Volume: 34, Issue:2

    Topics: Arteriovenous Shunt, Surgical; Aspirin; Blood Platelets; Cerebrovascular Disorders; Clofibrate; Coro

1978
Platelet inhibitors in the treatment of thrombosis.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1978, Volume: 1, Issue:3-4

    Topics: Adult; Aged; Arteriovenous Shunt, Surgical; Aspirin; Blood Platelets; Clinical Trials as Topic; Clof

1978
[Clinical prevention of thrombosis by antiplatelet agents].
    L'union medicale du Canada, 1979, Volume: 108, Issue:10

    Topics: Aspirin; Blood Platelets; Clofibrate; Dipyridamole; Humans; Hydroxychloroquine; Sulfinpyrazone; Thro

1979
Critical evaluation of platelet-inhibiting drugs in thrombotic disease.
    Progress in hematology, 1975, Volume: 9

    Topics: Arteriosclerosis; Aspirin; Blood Platelets; Cerebrovascular Disorders; Clinical Trials as Topic; Clo

1975
Platelet inhibition in the management of thrombosis.
    Thrombosis et diathesis haemorrhagica, 1974, Sep-30, Volume: 32, Issue:1

    Topics: Aspirin; Blindness; Blood Platelets; Cell Survival; Cerebrovascular Disorders; Dextrans; Dipyridamol

1974

Trials

7 trials available for hydroxychloroquine and Thrombosis

ArticleYear
The effect of hydroxychloroquine on thrombosis prevention and antiphospholipid antibody levels in primary antiphospholipid syndrome: A pilot open label randomized prospective study.
    Autoimmunity reviews, 2020, Volume: 19, Issue:4

    Topics: Adult; Antibodies, Antiphospholipid; Anticoagulants; Antiphospholipid Syndrome; Female; Humans; Hydr

2020
Hydroxychloroquine in the primary thrombosis prophylaxis of antiphospholipid antibody positive patients without systemic autoimmune disease.
    Lupus, 2018, Volume: 27, Issue:3

    Topics: Adult; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Blood Platelets; Erythrocytes; Femal

2018
Antithrombotic effects of drugs which suppress platelet function: their potential in prevention growth of tumour cells.
    Progress in clinical and biological research, 1982, Volume: 89

    Topics: Aspirin; Blood Platelets; Cardiovascular Diseases; Cell Division; Clinical Trials as Topic; Coronary

1982
The effectiveness of intermittent plantar venous compression in prevention of deep venous thrombosis after total hip arthroplasty.
    The Journal of arthroplasty, 1993, Volume: 8, Issue:1

    Topics: Aged; Bandages; Female; Femoral Vein; Foot; Gravity Suits; Heparin; Hip Prosthesis; Humans; Hydroxyc

1993
Platelet inhibitors in the treatment of thrombosis.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1978, Volume: 1, Issue:3-4

    Topics: Adult; Aged; Arteriovenous Shunt, Surgical; Aspirin; Blood Platelets; Clinical Trials as Topic; Clof

1978
Critical evaluation of platelet-inhibiting drugs in thrombotic disease.
    Progress in hematology, 1975, Volume: 9

    Topics: Arteriosclerosis; Aspirin; Blood Platelets; Cerebrovascular Disorders; Clinical Trials as Topic; Clo

1975
Platelet-inhibiting drugs in the prevention of clinical thrombotic disease (third of three parts).
    The New England journal of medicine, 1975, Dec-18, Volume: 293, Issue:25

    Topics: Anticoagulants; Aspirin; Clinical Trials as Topic; Clofibrate; Dipyridamole; Drug Evaluation; Fibrin

1975

Other Studies

26 other studies available for hydroxychloroquine and Thrombosis

ArticleYear
Eculizumab for refractory thrombosis in antiphospholipid syndrome.
    Blood advances, 2022, 02-22, Volume: 6, Issue:4

    Topics: Adolescent; Antibodies, Monoclonal, Humanized; Antiphospholipid Syndrome; Aspirin; Clopidogrel; Fema

2022
Catastrophic Anti-Phospholipid Syndrome in Systemic Lupus Erythematosus: A Tsunami in the Ocean.
    The Journal of the Association of Physicians of India, 2022, Volume: 70, Issue:4

    Topics: Adult; Antiphospholipid Syndrome; Cyclophosphamide; Female; Humans; Hydroxychloroquine; Immunoglobul

2022
Abdominal Visceral Infarction in 3 Patients with COVID-19.
    Emerging infectious diseases, 2020, Volume: 26, Issue:8

    Topics: Abdomen; Aged; Anticoagulants; Antiviral Agents; Betacoronavirus; Coronavirus Infections; COVID-19;

2020
Hydroxychloroquine reduces IL-6 and pro-thrombotic status.
    Autoimmunity reviews, 2020, Volume: 19, Issue:7

    Topics: Human Umbilical Vein Endothelial Cells; Humans; Hydroxychloroquine; Inflammation; Interleukin-6; Lup

2020
Clinically significant anticardiolipin antibodies associated with COVID-19.
    Journal of critical care, 2020, Volume: 59

    Topics: Adult; Antibodies, Anticardiolipin; Antibodies, Monoclonal, Humanized; Anticoagulants; Antiphospholi

2020
The rationale for Low-Molecular Weight Heparin (LMWH) use in SARS-CoV-2 infection
    Le infezioni in medicina, 2020, 06-01, Volume: 28, Issue:suppl 1

    Topics: Adenosine Monophosphate; Alanine; Anticoagulants; Antiviral Agents; Biomarkers; Coronavirus Infectio

2020
Pediatric catastrophic antiphospholipid syndrome patient evolving to systemic lupus erythematosus.
    Lupus, 2021, Volume: 30, Issue:1

    Topics: Adolescent; Antibodies, Antinuclear; Antiphospholipid Syndrome; Catastrophic Illness; Female; Hepari

2021
Association of Higher Hydroxychloroquine Blood Levels With Reduced Thrombosis Risk in Systemic Lupus Erythematosus.
    Arthritis & rheumatology (Hoboken, N.J.), 2021, Volume: 73, Issue:6

    Topics: Adult; Antirheumatic Agents; Chromatography, Liquid; Female; Fingers; Gangrene; Humans; Hydroxychlor

2021
Effect of Additional Treatments Combined with Conventional Therapies in Pregnant Patients with High-Risk Antiphospholipid Syndrome: A Multicentre Study.
    Thrombosis and haemostasis, 2018, Volume: 118, Issue:4

    Topics: Administration, Oral; Adult; Antibodies, Anticardiolipin; Antibodies, Antiphospholipid; Antiphosphol

2018
Hydroxychloroquine partially prevents endothelial dysfunction induced by anti-beta-2-GPI antibodies in an in vivo mouse model of antiphospholipid syndrome.
    PloS one, 2018, Volume: 13, Issue:11

    Topics: Animals; Antibodies, Anti-Idiotypic; Antiphospholipid Syndrome; beta 2-Glycoprotein I; Disease Model

2018
Hydroxychloroquine reverses the prothrombotic state in a mouse model of antiphospholipid syndrome: Role of reduced inflammation and endothelial dysfunction.
    PloS one, 2019, Volume: 14, Issue:3

    Topics: Animals; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Disease Models, Animal; Endothelia

2019
Antithrombotic effects of hydroxychloroquine in primary antiphospholipid syndrome patients.
    Journal of thrombosis and haemostasis : JTH, 2013, Volume: 11, Issue:10

    Topics: Adult; Antiphospholipid Syndrome; Humans; Hydroxychloroquine; Thrombosis

2013
Recurrent thrombosis prevention with intravenous immunoglobulin and hydroxychloroquine during pregnancy in a patient with history of catastrophic antiphospholipid syndrome and pregnancy loss.
    Journal of thrombosis and thrombolysis, 2014, Volume: 38, Issue:2

    Topics: Abortion, Spontaneous; Adult; Antiphospholipid Syndrome; Enzyme Inhibitors; Female; Humans; Hydroxyc

2014
Risk and protective factors for thrombosis in systemic lupus erythematosus: results from a large, multi-ethnic cohort.
    Annals of the rheumatic diseases, 2009, Volume: 68, Issue:2

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; California; Child; Female; Humans; Hydroxyc

2009
Risk factors for thrombosis and primary thrombosis prevention in patients with systemic lupus erythematosus with or without antiphospholipid antibodies.
    Arthritis and rheumatism, 2009, Jan-15, Volume: 61, Issue:1

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Antiphospholipid; Antirheuma

2009
The protective effect of antimalarial drugs on thrombovascular events in systemic lupus erythematosus.
    Arthritis and rheumatism, 2010, Volume: 62, Issue:3

    Topics: Adult; Antimalarials; Female; Humans; Hydroxychloroquine; Lupus Erythematosus, Systemic; Male; Middl

2010
Thrombovascular events in systemic lupus erythematosus: comment on the article by Jung et al.
    Arthritis and rheumatism, 2010, Volume: 62, Issue:9

    Topics: Antimalarials; Humans; Hydroxychloroquine; Lupus Erythematosus, Systemic; Thrombosis

2010
[Hydroxychloroquine: a new therapeutic approach to the thrombotic manifestations of antiphospholipid syndrome].
    La Revue de medecine interne, 2010, Volume: 31, Issue:12

    Topics: Annexin A5; Antiphospholipid Syndrome; Antirheumatic Agents; Biomarkers; Enzyme Inhibitors; Evidence

2010
[Classification of dermatologic manifestations in lupus erythematosus].
    Annales de medecine interne, 2003, Volume: 154, Issue:1

    Topics: Acitretin; Adrenal Cortex Hormones; Adult; Antimalarials; Clinical Trials as Topic; Dapsone; Dermato

2003
[THE USE OF HYDROXYCHLOROQUINE IN THE TREATMENT OF VASCULAR DISEASES].
    Minerva medica, 1963, Jul-21, Volume: 54

    Topics: Arteriosclerosis; Arteritis; Blood Proteins; Cholesterol; Coronary Disease; Fibrinogen; Humans; Hydr

1963
Systemic lupus erythematosus in a multiethnic cohort (LUMINA): XXVIII. Factors predictive of thrombotic events.
    Rheumatology (Oxford, England), 2005, Volume: 44, Issue:10

    Topics: Antibodies, Antiphospholipid; Antirheumatic Agents; Epidemiologic Methods; Female; Humans; Hydroxych

2005
[Prevention of thrombosis by thrombocyte inhibitors. 1. Cell regulation mechanisms and pharmacological modification].
    Ugeskrift for laeger, 1980, Jan-28, Volume: 142, Issue:5

    Topics: Adenosine Diphosphate; Aspirin; Blood Platelets; Cyclic AMP; Dextrans; Dipyridamole; Humans; Hydroxy

1980
Hydroxychloroquine reverses thrombogenic properties of antiphospholipid antibodies in mice.
    Circulation, 1997, Dec-16, Volume: 96, Issue:12

    Topics: Animals; Antibodies, Antiphospholipid; Antiphospholipid Syndrome; Dose-Response Relationship, Drug;

1997
[Antiplatelet drugs (author's transl)].
    Anesthesie, analgesie, reanimation, 1979, Volume: 36, Issue:7-8

    Topics: Aspirin; Blood Platelets; Clofibrate; Dipyridamole; Female; Humans; Hydroxychloroquine; Ischemic Att

1979
[Clinical use of anti-aggregative agents].
    Bulletin der Schweizerischen Akademie der Medizinischen Wissenschaften, 1973, Volume: 29, Issue:4

    Topics: Aspirin; Dipyridamole; Humans; Hydroxychloroquine; Platelet Adhesiveness; Thromboembolism; Thromboph

1973
Platelet reactions and immune processes. IV. The inhibition of complement by pyrazole compounds and other inhibitors of platelet reactions.
    Canadian journal of microbiology, 1970, Volume: 16, Issue:2

    Topics: Animals; Blood Coagulation; Blood Platelets; Chloroquine; Complement Inactivator Proteins; Erythrocy

1970