Page last updated: 2024-10-28

hydroxychloroquine and Symptom Cluster

hydroxychloroquine has been researched along with Symptom Cluster in 23 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Research Excerpts

ExcerptRelevanceReference
"The authors describe the first case of drug rash with eosinophilia and systemic symptoms syndrome caused by hydroxychloroquine treatment in a male patient affected by seronegative arthritis."7.74Hydroxychloroquine-induced DRESS syndrome. ( Arcaro, G; Bambara, LM; Biasi, D; Caramaschi, P; Marchetta, A; Volpe, A, 2008)
"A fasciitis-sclerodermia-eosinophilia syndrome developed in four female patients, aged between 55 and 75 years, after the ingestion of tryptophan, 1."7.68[Tryptophan-induced fasciitis-scleroderma-eosinophilia syndrome]. ( Gross, WL; Reinhold-Keller, E; Schnabel, A; Wolff, HH, 1991)
"Hydroxychloroquine in lower doses is an effective treatment for porphyria cutanea tarda; at doses used to treat systemic lupus erythematosus and subacute cutaneous lupus, there is a potentially life-threatening complication of hepatotoxicity."5.48The devil's in the dosing: severe drug-induced liver injury in a hydroxychloroquine-naive patient with subacute cutaneous lupus erythematosus and porphyria cutanea tarda. ( Ettel, M; McCune, WJ; Pearson, TL; Roofeh, D; Silver, S; Sunkara, B, 2018)
"The authors describe the first case of drug rash with eosinophilia and systemic symptoms syndrome caused by hydroxychloroquine treatment in a male patient affected by seronegative arthritis."3.74Hydroxychloroquine-induced DRESS syndrome. ( Arcaro, G; Bambara, LM; Biasi, D; Caramaschi, P; Marchetta, A; Volpe, A, 2008)
"A fasciitis-sclerodermia-eosinophilia syndrome developed in four female patients, aged between 55 and 75 years, after the ingestion of tryptophan, 1."3.68[Tryptophan-induced fasciitis-scleroderma-eosinophilia syndrome]. ( Gross, WL; Reinhold-Keller, E; Schnabel, A; Wolff, HH, 1991)
"Rowell's syndrome is a rare disorder characterised by an association of lupus erythematosus with erythema multiforme (EM)-like skin lesions."1.56Rowell's syndrome: a rare but distinct entity in rheumatology. ( Chandra, A; Karmakar, P; Ray, AK; Saha, SK, 2020)
"Hydroxychloroquine in lower doses is an effective treatment for porphyria cutanea tarda; at doses used to treat systemic lupus erythematosus and subacute cutaneous lupus, there is a potentially life-threatening complication of hepatotoxicity."1.48The devil's in the dosing: severe drug-induced liver injury in a hydroxychloroquine-naive patient with subacute cutaneous lupus erythematosus and porphyria cutanea tarda. ( Ettel, M; McCune, WJ; Pearson, TL; Roofeh, D; Silver, S; Sunkara, B, 2018)
"Overlap syndromes are known to occur with connective-tissue diseases (CTDs)."1.43Lupus erythematosus and localized scleroderma coexistent at the same sites: a rare presentation of overlap syndrome of connective-tissue diseases. ( Fazel, N; Lynch, PJ; Pascucci, A, 2016)
"While pleuropulmonary involvement in systemic lupus erythematosus (SLE) is a common occurrence, shrinking lung syndrome (SLS) is a rare complication of SLE, particularly in children."1.39Symptoms of shrinking lung syndrome reveal systemic lupus erythematosus in a 12-year-old girl. ( Berner, R; Geiger, J; Heinzmann, A; Hufnagel, M; Meinicke, H, 2013)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19904 (17.39)18.7374
1990's2 (8.70)18.2507
2000's4 (17.39)29.6817
2010's10 (43.48)24.3611
2020's3 (13.04)2.80

Authors

AuthorsStudies
Castillo Dayer, PV1
Lozano Rivas, N1
Martínez Ferrín, JJ1
Victoria Martínez, AM1
Sánchez-Pedreño Guillen, P1
Marras Fernández-Cid, C1
Gutta, S1
Das, S1
Kodiatte, TA1
Vimala, LR1
Ward, JM1
Hess, JN1
Davis, LS1
Chandra, A1
Saha, SK1
Ray, AK1
Karmakar, P1
Psarianos, P1
Kwan, JYY1
Dell, S1
Wee, WB1
Rey-McIntyre, K1
Chen, H1
Dissanayake, D1
Laxer, RM1
Shum, A1
Liu, FF1
Yip, KW1
Schissler, C1
Banea, S1
Tortel, MC1
Mahé, A1
Sunkara, B1
Roofeh, D1
Silver, S1
Pearson, TL1
Ettel, M1
McCune, WJ1
Scuderi, L1
Caltabiano, R1
Torrisi, GG1
Longo, V1
Pavone, A1
De Pasquale, R1
Pascucci, A1
Lynch, PJ1
Fazel, N1
Schmutz, JL1
Barbaud, A1
Tréchot, P1
Efe, C1
Purnak, T1
Ozaslan, E1
Ozbalkan, Z1
Karaaslan, Y1
Altiparmak, E1
Muratori, P1
Wahlin, S1
Vashi, N1
Newlove, T1
Chu, J1
Patel, R1
Stein, J1
Lent, M1
Jagwani, S1
Ward, D1
Meinicke, H1
Heinzmann, A1
Geiger, J1
Berner, R1
Hufnagel, M1
Dereure, O1
Guilhou, JJ1
BUTTERWORTH, RF1
Al-Raqum, HA1
Uppal, SS1
Al-Mutairy, M1
Kumari, R1
Volpe, A1
Marchetta, A1
Caramaschi, P1
Biasi, D1
Bambara, LM1
Arcaro, G1
Balogh, E1
Nagy-Vezekényi, K1
Fórizs, E1
Lopez, LR1
Davis, KC1
Kohler, PF1
Schocket, AL1
Shteyngarts, AR1
Warner, MR1
Camisa, C1
Keczkes, K1
Jadhav, P1
Schnabel, A1
Reinhold-Keller, E1
Wolff, HH1
Gross, WL1

Reviews

1 review available for hydroxychloroquine and Symptom Cluster

ArticleYear
Lupus erythematosus associated with erythema multiforme: does Rowell's syndrome exist?
    Journal of the American Academy of Dermatology, 1999, Volume: 40, Issue:5 Pt 1

    Topics: Adult; Azathioprine; Cathartics; Dermatologic Agents; Diagnosis, Differential; Erythema Multiforme;

1999

Other Studies

22 other studies available for hydroxychloroquine and Symptom Cluster

ArticleYear
Belimumab treatment in rhupus: A case report with severe skin involvement.
    Dermatologic therapy, 2019, Volume: 32, Issue:5

    Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arthritis, Rheumatoid; Drug Therap

2019
Organising pneumonia in Rhupus syndrome.
    BMJ case reports, 2019, Dec-19, Volume: 12, Issue:12

    Topics: Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis; Cough; Diagnosis, Differential; Drug Ther

2019
Targetoid-like Lesions in the Setting of Systemic Lupus Erythematosus: A Case of Rowell Syndrome.
    The Journal of rheumatology, 2020, Volume: 47, Issue:2

    Topics: Adrenal Cortex Hormones; Adult; Antirheumatic Agents; Diagnosis, Differential; Erythema Multiforme;

2020
Rowell's syndrome: a rare but distinct entity in rheumatology.
    BMJ case reports, 2020, Sep-23, Volume: 13, Issue:9

    Topics: Adolescent; Antibodies, Antinuclear; Antipyretics; Arthralgia; Drug Therapy, Combination; Erythema M

2020
COPA Syndrome (Ala239Pro) Presenting with Isolated Follicular Bronchiolitis in Early Childhood: Case Report.
    Journal of clinical immunology, 2021, Volume: 41, Issue:7

    Topics: Bronchiolitis; Child; Coatomer Protein; Glucocorticoids; Humans; Hydroxychloroquine; Immunosuppressi

2021
[A new case of Rowell's syndrome].
    Annales de dermatologie et de venereologie, 2017, Volume: 144, Issue:4

    Topics: Adrenal Cortex Hormones; Adult; Anti-Ulcer Agents; Cheilitis; Diagnosis, Differential; Erythema Mult

2017
The devil's in the dosing: severe drug-induced liver injury in a hydroxychloroquine-naive patient with subacute cutaneous lupus erythematosus and porphyria cutanea tarda.
    Lupus, 2018, Volume: 27, Issue:8

    Topics: Adult; Blister; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Dose-Response Relat

2018
Rowell syndrome.
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2015, Volume: 150, Issue:3

    Topics: Adult; Drug Therapy, Combination; Erythema Multiforme; Female; Humans; Hydroxychloroquine; Lupus Ery

2015
Lupus erythematosus and localized scleroderma coexistent at the same sites: a rare presentation of overlap syndrome of connective-tissue diseases.
    Cutis, 2016, Volume: 97, Issue:5

    Topics: Antibodies, Antinuclear; Antimalarials; Female; Glucocorticoids; Humans; Hydroxychloroquine; Lupus E

2016
[Hydroxychloroquine and DRESS].
    Annales de dermatologie et de venereologie, 2008, Volume: 135, Issue:12

    Topics: Antirheumatic Agents; Drug Eruptions; Eosinophilia; Humans; Hydroxychloroquine; Male; Middle Aged; P

2008
Autoimmune liver disease in patients with systemic lupus erythematosus: a retrospective analysis of 147 cases.
    Scandinavian journal of gastroenterology, 2011, Volume: 46, Issue:6

    Topics: Adult; Antibodies, Antinuclear; Azathioprine; Biopsy; Enzyme-Linked Immunosorbent Assay; Female; Hep

2011
Graham-Little-Piccardi-Lassueur syndrome.
    Dermatology online journal, 2011, Oct-15, Volume: 17, Issue:10

    Topics: Adult; Alopecia; Axilla; Doxycycline; Female; Groin; Humans; Hydroxychloroquine; Hyperpigmentation;

2011
Rowell's syndrome: a distinct clinical entity or a coincidence of diagnoses?
    International journal of dermatology, 2012, Volume: 51, Issue:6

    Topics: Administration, Topical; Antibodies, Antinuclear; Antirheumatic Agents; Erythema Multiforme; Female;

2012
Symptoms of shrinking lung syndrome reveal systemic lupus erythematosus in a 12-year-old girl.
    Pediatric pulmonology, 2013, Volume: 48, Issue:12

    Topics: Chest Pain; Child; Cyclophosphamide; Diaphragm; Dyspnea; Female; Humans; Hydroxychloroquine; Immunos

2013
[Eosinophilic-like erythema: a clinical subset of Wells' eosinophilic cellulitis responding to antimalarial drugs?].
    Annales de dermatologie et de venereologie, 2002, Volume: 129, Issue:5 Pt 1

    Topics: Adult; Antimalarials; Cellulitis; Eosinophilia; Erythema; Female; Humans; Hydroxychloroquine; Syndro

2002
The burning skin syndrome: treatment with hydroxychloroquine.
    The Medical journal of Australia, 1960, Sep-17, Volume: 47(2)

    Topics: Chloroquine; Dermatology; Humans; Hydroxychloroquine; Musculoskeletal Diseases; Pain; Paresthesia; S

1960
Shrinking lung syndrome as a presenting manifestation of systemic lupus erythematosus in a female Kuwaiti.
    Clinical rheumatology, 2006, Volume: 25, Issue:3

    Topics: Adult; Diagnosis, Differential; Drug Therapy, Combination; Dyspnea; Female; Glucocorticoids; Humans;

2006
Hydroxychloroquine-induced DRESS syndrome.
    Clinical rheumatology, 2008, Volume: 27, Issue:4

    Topics: Antirheumatic Agents; Arthritis; Eosinophilia; Exanthema; Fever; Humans; Hydroxychloroquine; Male; M

2008
REM syndrome: an immediate therapeutic response to hydroxychloroquine sulphate.
    Acta dermato-venereologica, 1980, Volume: 60, Issue:2

    Topics: Adult; Erythema; Female; Glycosaminoglycans; Humans; Hydroxychloroquine; Mucins; Skin; Skin Diseases

1980
The hypocomplementemic urticarial-vasculitis syndrome: therapeutic response to hydroxychloroquine.
    The Journal of allergy and clinical immunology, 1984, Volume: 73, Issue:5 Pt 1

    Topics: Adult; Biopsy; Complement Activating Enzymes; Complement C1q; Hemolytic Plaque Technique; Humans; Hy

1984
REM syndrome (reticular erythematous mucinosis): report of a further case or variant of it.
    Archives of dermatology, 1977, Volume: 113, Issue:3

    Topics: Adult; Back; Erythema; Female; Gingival Diseases; Glycosaminoglycans; Histocytochemistry; Humans; Hy

1977
[Tryptophan-induced fasciitis-scleroderma-eosinophilia syndrome].
    Deutsche medizinische Wochenschrift (1946), 1991, Aug-02, Volume: 116, Issue:31-32

    Topics: Aged; Creatine Kinase; Diagnosis, Differential; Eosinophilia; Fasciitis; Female; Fructose-Bisphospha

1991