hydroxychloroquine has been researched along with Stillbirth in 5 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Stillbirth: The event that a FETUS is born dead or stillborn.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydroxychloroquine (HCQ) is often needed to manage disease activity in systemic lupus erythematosus (SLE) during pregnancy." | 9.12 | Hydroxychloroquine in lupus pregnancy. ( Clowse, ME; Magder, L; Petri, M; Witter, F, 2006) |
| "Hydroxychloroquine (HCQ) is often needed to manage disease activity in systemic lupus erythematosus (SLE) during pregnancy." | 5.12 | Hydroxychloroquine in lupus pregnancy. ( Clowse, ME; Magder, L; Petri, M; Witter, F, 2006) |
| "COVID-19 and preeclampsia (preE) share the ANG-II mediated endothelial dysfunction, resulting from a significant dysregulation of RAS and an imbalanced proportion of anti-angiogenic and pro-angiogenic soluble plasmatic factors." | 1.72 | Imbalanced Angiogenesis in Pregnancies Complicated by SARS-CoV-2 Infection. ( Acampora, E; Arienti, F; Carrer, A; Casati, M; Gambacorti-Passerini, C; Giardini, V; Ornaghi, S; Vasarri, MV; Vergani, P, 2022) |
| "Pregnancy seems to increase the risk of thrombotic thrombocytopenic purpura (TTP) relapses and make the TTP more severe in any of the pregnancy trimesters, or even during the postpartum period." | 1.62 | A COVID-19 pregnant patient with thrombotic thrombocytopenic purpura: a case report. ( Afrooz, N; Aminimoghaddam, S; Mahmoudzadeh, F; Motaghi Nejad, O; Nasiri, S, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 3 (60.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giardini, V | 1 |
| Ornaghi, S | 1 |
| Gambacorti-Passerini, C | 1 |
| Casati, M | 1 |
| Carrer, A | 1 |
| Acampora, E | 1 |
| Vasarri, MV | 1 |
| Arienti, F | 1 |
| Vergani, P | 1 |
| Di Mascio, D | 1 |
| D'Antonio, F | 1 |
| Aminimoghaddam, S | 1 |
| Afrooz, N | 1 |
| Nasiri, S | 1 |
| Motaghi Nejad, O | 1 |
| Mahmoudzadeh, F | 1 |
| Tedeschi, SK | 1 |
| Guan, H | 1 |
| Fine, A | 1 |
| Costenbader, KH | 1 |
| Bermas, B | 1 |
| Clowse, ME | 1 |
| Magder, L | 1 |
| Witter, F | 1 |
| Petri, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Three-arm, Multicenter, Open-label Randomized Controlled Trial of Hydroxychloroquine and Low-dose Prednisone on Recurrent Spontaneous Abortion With Undifferentiated Connective Tissue Diseases: Protocol for the Immunosuppressant Regimens for Living FEtus[NCT03671174] | 420 participants (Anticipated) | Interventional | 2019-08-02 | Recruiting | |||
| Hydroxychloroquine Exposure in Systemic Lupus Erythematosus (SLE)[NCT03802188] | 3,700 participants (Anticipated) | Observational | 2018-05-09 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for hydroxychloroquine and Stillbirth
| Article | Year |
|---|---|
Hydroxychloroquine in lupus pregnancy.
Topics: Abortion, Spontaneous; Adult; Antirheumatic Agents; Female; Glucocorticoids; Humans; Hydroxychloroqu | 2006 |
Hydroxychloroquine in lupus pregnancy.
Topics: Abortion, Spontaneous; Adult; Antirheumatic Agents; Female; Glucocorticoids; Humans; Hydroxychloroqu | 2006 |
Hydroxychloroquine in lupus pregnancy.
Topics: Abortion, Spontaneous; Adult; Antirheumatic Agents; Female; Glucocorticoids; Humans; Hydroxychloroqu | 2006 |
Hydroxychloroquine in lupus pregnancy.
Topics: Abortion, Spontaneous; Adult; Antirheumatic Agents; Female; Glucocorticoids; Humans; Hydroxychloroqu | 2006 |
4 other studies available for hydroxychloroquine and Stillbirth
| Article | Year |
|---|---|
Imbalanced Angiogenesis in Pregnancies Complicated by SARS-CoV-2 Infection.
Topics: Angiogenesis Inducing Agents; Biomarkers; COVID-19; Female; Fibrinolytic Agents; Humans; Hydroxychlo | 2022 |
Perinatal mortality and morbidity of SARS-COV-2 infection during pregnancy in European countries: Findings from an international study.
Topics: Adult; Anti-Bacterial Agents; Anticoagulants; Antiviral Agents; Asia; Asymptomatic Infections; Austr | 2021 |
A COVID-19 pregnant patient with thrombotic thrombocytopenic purpura: a case report.
Topics: Acute Kidney Injury; Amphetamine-Related Disorders; Antiviral Agents; COVID-19; Drug Combinations; E | 2021 |
Organ-specific systemic lupus erythematosus activity during pregnancy is associated with adverse pregnancy outcomes.
Topics: Abortion, Spontaneous; Adrenal Cortex Hormones; Adult; Antirheumatic Agents; Female; Humans; Hydroxy | 2016 |