hydroxychloroquine has been researched along with Stargardt Disease in 1 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Stargardt Disease: A juvenile-onset macular dystrophy characterized by progressive loss of VISUAL ACUITY with normal acuity in peripheral VISUAL FIELDS. Other associated clinical features may include LIPOFUSCIN fundus autofluorescence, atrophy of the RETINAL PIGMENT EPITHELIUM, loss of color vision, PHOTOPHOBIA and PARACENTRAL SCOTOMA. Germline mutations in the ABCA4 gene have been identified in recessive and dominant diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To describe a series of patients with Stargardt disease (STGD1) exhibiting a phenotype usually associated with hydroxychloroquine (HCQ) retinopathy on spectral domain-optical coherence tomography (SD-OCT)." | 7.83 | Recessive Stargardt disease phenocopying hydroxychloroquine retinopathy. ( Allikmets, R; Greenstein, VC; Lee, W; Nõupuu, K; Tsang, S; Zernant, J, 2016) |
| "To describe a series of patients with Stargardt disease (STGD1) exhibiting a phenotype usually associated with hydroxychloroquine (HCQ) retinopathy on spectral domain-optical coherence tomography (SD-OCT)." | 3.83 | Recessive Stargardt disease phenocopying hydroxychloroquine retinopathy. ( Allikmets, R; Greenstein, VC; Lee, W; Nõupuu, K; Tsang, S; Zernant, J, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nõupuu, K | 1 |
| Lee, W | 1 |
| Zernant, J | 1 |
| Greenstein, VC | 1 |
| Tsang, S | 1 |
| Allikmets, R | 1 |
1 other study available for hydroxychloroquine and Stargardt Disease
| Article | Year |
|---|---|
Recessive Stargardt disease phenocopying hydroxychloroquine retinopathy.
Topics: Adult; Antimalarials; ATP-Binding Cassette Transporters; Child; Electroretinography; Female; Genes, | 2016 |