Page last updated: 2024-10-28

hydroxychloroquine and Skin Neoplasms

hydroxychloroquine has been researched along with Skin Neoplasms in 13 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Skin Neoplasms: Tumors or cancer of the SKIN.

Research Excerpts

ExcerptRelevanceReference
"To characterise the incidence rate of skin cancer associated with methotrexate and hydroxychloroquine in older adults with rheumatoid arthritis (RA)."8.31Risk of malignant melanoma and non-melanoma skin cancer in rheumatoid arthritis patients initiating methotrexate versus hydroxychloroquine: a cohort study. ( Chen, SK; Desai, RJ; Gautam, N; Glynn, RJ; He, M; Kim, SC; Lee, H; Vine, SM; Weinblatt, ME, 2023)
"A 45-year-old woman with generalized cutaneous pseudolymphoma of Spiegler-Fendt was successfully treated with hydroxychloroquine."7.66Treatment of cutaneous pseudolymphoma with hydroxychloroquine. ( Stoll, DM, 1983)
"Hydroxychloroquine was suspected of causing an anxiety/psychotic disorder in one patient."7.11A lead-in safety study followed by a phase 2 clinical trial of dabrafenib, trametinib and hydroxychloroquine in advanced BRAFV600 mutant melanoma patients previously treated with BRAF-/MEK-inhibitors and immune checkpoint inhibitors. ( Awada, G; Fasolino, G; Kruse, V; Neyns, B; Schwarze, JK; Tijtgat, J, 2022)
" Ulipristal for uterine fibroids : market withdrawal due to risk of severe liver injury."5.12[Pharmacovigilance update]. ( Ekobena, P; Ivanyuk, A; Livio, F, 2021)
"To characterise the incidence rate of skin cancer associated with methotrexate and hydroxychloroquine in older adults with rheumatoid arthritis (RA)."4.31Risk of malignant melanoma and non-melanoma skin cancer in rheumatoid arthritis patients initiating methotrexate versus hydroxychloroquine: a cohort study. ( Chen, SK; Desai, RJ; Gautam, N; Glynn, RJ; He, M; Kim, SC; Lee, H; Vine, SM; Weinblatt, ME, 2023)
" Consequently, hydroxychloroquine and topical glucocorticoids therapy were initiated with reported improvement in pruritus, erythema, and scale."3.74Chronic cutaneous lupus erythematosus in vitiligo. ( Bossenbroek, NM; Johnson, H; Meehan, SA; Pomeranz, MK; Robles, M; Rosenman, K, 2008)
"A 45-year-old woman with generalized cutaneous pseudolymphoma of Spiegler-Fendt was successfully treated with hydroxychloroquine."3.66Treatment of cutaneous pseudolymphoma with hydroxychloroquine. ( Stoll, DM, 1983)
"Hydroxychloroquine was suspected of causing an anxiety/psychotic disorder in one patient."3.11A lead-in safety study followed by a phase 2 clinical trial of dabrafenib, trametinib and hydroxychloroquine in advanced BRAFV600 mutant melanoma patients previously treated with BRAF-/MEK-inhibitors and immune checkpoint inhibitors. ( Awada, G; Fasolino, G; Kruse, V; Neyns, B; Schwarze, JK; Tijtgat, J, 2022)
"Thalidomide treatment finally led to complete remission."1.36Disseminated cutaneous lymphoid hyperplasia of 12 years' duration triggered by vaccination. ( Beylot-Barry, M; Doutre, MS; Pham-Ledard, A; Vergier, B, 2010)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19902 (15.38)18.7374
1990's0 (0.00)18.2507
2000's2 (15.38)29.6817
2010's3 (23.08)24.3611
2020's6 (46.15)2.80

Authors

AuthorsStudies
Yumine, A1
Tsuji, G1
Awada, G1
Schwarze, JK1
Tijtgat, J1
Fasolino, G1
Kruse, V1
Neyns, B1
Lee, H1
Chen, SK1
Gautam, N1
Vine, SM1
He, M1
Desai, RJ1
Weinblatt, ME1
Glynn, RJ1
Kim, SC1
Han, B1
Liu, H1
Wang, H1
Mizuno, H1
Takahagi, S1
Morita, S1
Kamegashira, A1
Tanaka, A1
Ekobena, P1
Ivanyuk, A1
Livio, F1
Gardair Bouchy, C1
Kerdraon, R1
Kluger, N1
Armingaud, P1
Wakosa, A1
Estève, E1
Amann, VC1
Dreier, J1
Ignatova, D1
Kamarashev, J1
Kerl, K1
Kempf, W1
Pascolo, S1
Dummer, R1
Cozzio, A1
Guenova, E1
Johnson, H1
Bossenbroek, NM1
Rosenman, K1
Meehan, SA1
Robles, M1
Pomeranz, MK1
Pham-Ledard, A1
Vergier, B1
Doutre, MS1
Beylot-Barry, M1
Gupta, U1
Barman, KD1
Saify, K1
Stoll, DM1
Roenigk, HH1
Lesowitz, SA1

Reviews

2 reviews available for hydroxychloroquine and Skin Neoplasms

ArticleYear
Idiopathic Cutaneous Pseudolymphoma Treated Successfully with Hydroxychloroquine: A Case Report and Literature Review.
    Acta dermato-venereologica, 2022, 10-20, Volume: 102

    Topics: Humans; Hydroxychloroquine; Pseudolymphoma; Skin Diseases; Skin Neoplasms

2022
[Pharmacovigilance update].
    Revue medicale suisse, 2021, Jan-13, Volume: 17, Issue:720-1

    Topics: Adenosine Monophosphate; Alanine; Cleft Lip; Contraindications, Drug; COVID-19 Drug Treatment; Cytok

2021

Trials

1 trial available for hydroxychloroquine and Skin Neoplasms

ArticleYear
A lead-in safety study followed by a phase 2 clinical trial of dabrafenib, trametinib and hydroxychloroquine in advanced BRAFV600 mutant melanoma patients previously treated with BRAF-/MEK-inhibitors and immune checkpoint inhibitors.
    Melanoma research, 2022, 06-01, Volume: 32, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Humans; Hydroxychloroquine; Imidazoles; Immune Check

2022

Other Studies

10 other studies available for hydroxychloroquine and Skin Neoplasms

ArticleYear
Hydroxychloroquine induces matrix metalloproteinase 1 expression and apoptosis in neurofibromatosis type 1 Schwann cells.
    Journal of dermatological science, 2021, Volume: 104, Issue:2

    Topics: Antimalarials; Apoptosis; Benzamides; Cell Line, Tumor; Cell Proliferation; Collagen Type I, alpha 1

2021
Risk of malignant melanoma and non-melanoma skin cancer in rheumatoid arthritis patients initiating methotrexate versus hydroxychloroquine: a cohort study.
    Clinical and experimental rheumatology, 2023, Volume: 41, Issue:1

    Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Carcinoma, Basal Cell; Carcinoma, Squamous Cell;

2023
A case of multiple nodular cutaneous B-cell pseudolymphoma successfully treated with glucocorticoid, methotrexate, and hydroxychloroquine.
    Dermatologic therapy, 2022, Volume: 35, Issue:11

    Topics: Diagnosis, Differential; Glucocorticoids; Humans; Hydroxychloroquine; Methotrexate; Pseudolymphoma;

2022
[Cutaneous lymphoid hyperplasia (pseudolymphoma) on the red dye of a tattoo].
    Annales de pathologie, 2013, Volume: 33, Issue:4

    Topics: Adrenal Cortex Hormones; Adult; Biopsy; Coloring Agents; Diagnosis, Differential; Drug Eruptions; Ge

2013
Disseminated Primary Cutaneous CD8+ Small/Medium-sized Pleomorphic T-cell Lymphoma Responding to Hydroxychloroquine.
    Acta dermato-venereologica, 2015, Volume: 95, Issue:5

    Topics: Antimalarials; Biopsy, Needle; CD8 Antigens; Dose-Response Relationship, Drug; Drug Administration S

2015
Chronic cutaneous lupus erythematosus in vitiligo.
    Dermatology online journal, 2008, Oct-15, Volume: 14, Issue:10

    Topics: Autoimmunity; Carcinoma, Squamous Cell; Clobetasol; Diabetes Complications; Diagnostic Errors; Drug

2008
Disseminated cutaneous lymphoid hyperplasia of 12 years' duration triggered by vaccination.
    Dermatology (Basel, Switzerland), 2010, Volume: 220, Issue:2

    Topics: Adolescent; B-Lymphocytes; CD3 Complex; Cyclins; DNA-Binding Proteins; Female; Hepatitis B Vaccines;

2010
Squamous cell carcinoma complicating an untreated chronic discoid lupus erythematosus (CDLE) lesion in a black female.
    The Journal of dermatology, 2005, Volume: 32, Issue:12

    Topics: Adult; Biopsy, Needle; Black People; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Comb

2005
Treatment of cutaneous pseudolymphoma with hydroxychloroquine.
    Journal of the American Academy of Dermatology, 1983, Volume: 8, Issue:5

    Topics: Diagnosis, Differential; Female; Humans; Hydroxychloroquine; Lymphoma; Middle Aged; Skin Neoplasms

1983
Lymphocytoma cutis.
    Archives of dermatology, 1970, Volume: 101, Issue:2

    Topics: Humans; Hydroxychloroquine; Lymphoma, Non-Hodgkin; Male; Methylprednisolone; Middle Aged; Skin Neopl

1970