hydroxychloroquine has been researched along with Sicca Syndrome in 126 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the safety and efficacy of oral hydroxychloroquine in treating dry eye disease associated with pSS." | 9.69 | Safety and Efficacy of Oral Hydroxychloroquine in the Treatment of Ophthalmic Disease Associated with Sjögren's Syndrome. ( Bing, Z; Fang, W; Jie, X; Qihui, L; Qingqing, Z; Xinyue, H, 2023) |
| "The effect of hydroxychloroquine (HCQ) on dry eye has not been fully determined." | 9.22 | Effect of Hydroxychloroquine Treatment on Dry Eyes in Subjects with Primary Sjögren's Syndrome: a Double-Blind Randomized Control Study. ( Kim, MK; Lee, EB; Lee, EY; Lee, HJ; Lee, WW; Wee, WR; Yoon, CH, 2016) |
| "YFU combined hydroxychloroquine sulfate tablet showed better effects in treating Sjogren's syndrome patients than using Chinese medicine or Western medicine alone." | 9.16 | [Analysis of the clinical efficacy of yiqi fumai injection combined hydroxychloroquine sulfate tablet for treating Sjogren's syndrome]. ( Chen, FY; Wang, H; Xue, B, 2012) |
| "To systematically review and assess the efficacy and safety of hydroxychloroquine (HCQ) for treating primary Sjogren's syndrome (pSS)." | 8.95 | Is hydroxychloroquine effective in treating primary Sjogren's syndrome: a systematic review and meta-analysis. ( Hua, H; Wang, SQ; Wei, P; Zhang, LW, 2017) |
| "Hydroxychloroquine (HCQ) therapy decreased immunoglobulin (Ig) levels in patients with Sjögren syndrome (SS) and rheumatoid arthritis (RA) in previous studies." | 8.12 | Hydroxychloroquine Therapy and Serum Immunoglobulin Levels in Women with IgG Subclass Deficiency and Systemic Lupus Erythematosus, Sjögren Syndrome, and Rheumatoid Arthritis: A Retrospective Study. ( Barton, JC; Bertoli, LF, 2022) |
| "To determine whether taking hydroxychloroquine (HCQ) could prevent the development of new-onset diabetes mellitus (DM) among patients with Sjögren syndrome (SS)." | 7.91 | Hydroxychloroquine was associated with reduced risk of new-onset diabetes mellitus in patients with Sjögren syndrome. ( Chen, TH; Chiou, JY; Hung, YM; Lai, TY; Wang, YH; Wei, JC, 2019) |
| " The aim of this report was to draw attention to the localized mucocutaneous bluish-grey hyperpigmentation induced by hydroxychloroquine with a case presentation and a review of the literature." | 7.74 | Hydroxychloroquine-induced hyperpigmentation: a case report. ( Budak, BS; Gurbuz, U; Kacar, C; Melikoglu, M; Melikoglu, MA, 2008) |
| "To determine whether (i) cholinesterase activity is increased in the saliva of patients with primary Sjogren's syndrome (pSS), (ii) increased levels of cholinesterase of lymphocyte origin could interfere with the secretory activity of submandibular acinar cells, and (iii) hydroxychloroquine at therapeutic doses could interfere with cholinesterase activity." | 7.73 | Hydroxychloroquine therapy in patients with primary Sjögren's syndrome may improve salivary gland hypofunction by inhibition of glandular cholinesterase. ( Caulfield, VL; Christmas, SE; Dawson, LJ; Field, AE; Smith, PM; Stanbury, JB, 2005) |
| " A case of psoriatic onychoperiostitis precipitated by hydroxychloroquine therapy is reported." | 7.69 | Recurrent psoriatic onychoperiostitis induced by hydroxychloroquine. ( Cribier, B; Javier, RM; Kuntz, JL; Pflumio, F; Sibilia, J, 1995) |
| " We have found that baricitinib might be effective and safe in pSS in a pilot study." | 7.30 | A multi-center, open-label, randomized study to explore efficacy and safety of baricitinib in active primary Sjogren's syndrome patients. ( Bai, W; Leng, X; Li, H; Shi, X; Wei, W; Xu, H; Yang, F; Zeng, X; Zhang, L; Zhang, Y; Zhao, Y, 2023) |
| "To evaluate the safety and efficacy of oral hydroxychloroquine in treating dry eye disease associated with pSS." | 5.69 | Safety and Efficacy of Oral Hydroxychloroquine in the Treatment of Ophthalmic Disease Associated with Sjögren's Syndrome. ( Bing, Z; Fang, W; Jie, X; Qihui, L; Qingqing, Z; Xinyue, H, 2023) |
| "There is a lack of information on the role of chronic use of hydroxychloroquine during the SARS-CoV-2 outbreak." | 5.62 | Chronic use of hydroxychloroquine did not protect against COVID-19 in a large cohort of patients with rheumatic diseases in Brazil. ( Abreu, MM; Albuquerque, CP; Araújo, NC; Bacchiega, AB; Bianchi, DV; Bica, B; Bonfa, ED; Borba, EF; Brito, DCSE; de Souza, VA; Duarte, ÂLBP; Fernandes, PR; Ferreira, GA; Gomes, KWP; Guimarães, MP; Junior, LFR; Kakehasi, AM; Klumb, EM; Lacerda, MVG; Lanna, CCD; Marques, CDL; Monticielo, OA; Mota, LMH; Munhoz, GA; Paiva, ES; Pereira, HLA; Pileggi, GS; Pinheiro, MM; Provenza, JR; Reis, APMG; Reis-Neto, ET; Ribeiro, SLE; Sampaio, CSJC; Sampaio, VS; Santo, RCE; Sato, EI; Skare, T; Valim, V; Xavier, RM, 2021) |
| "Annular erythema is one of the cutaneous manifestations of Sjögren's syndrome (SS)." | 5.62 | Efficacy of hydroxychloroquine for treating annular erythema associated with Sjögren's syndrome. ( Amagai, M; Arakawa, H; Miyamoto, J; Murakami, K; Sujino, K; Tanaka, R; Tanese, K; Tanikawa, A, 2021) |
| " Univariate and multivariate analysis showed that long-term use of HCQ, menopause, and income were related to sleep quality." | 5.56 | Long-term hydroxychloroquine therapy improves the quality of sleep in patients with primary Sjögren's syndrome: a real-world study. ( Chen, J; Chen, Z; Guan, P; Ran, R; Sun, C, 2020) |
| "Lupus alopecia is usually difficult to treat." | 5.48 | Dramatic effect of hydroxychloroquine on lupus alopecia. ( Igari, S; Yamamoto, T, 2018) |
| "The effect of hydroxychloroquine (HCQ) on dry eye has not been fully determined." | 5.22 | Effect of Hydroxychloroquine Treatment on Dry Eyes in Subjects with Primary Sjögren's Syndrome: a Double-Blind Randomized Control Study. ( Kim, MK; Lee, EB; Lee, EY; Lee, HJ; Lee, WW; Wee, WR; Yoon, CH, 2016) |
| "To evaluate the efficacy of hydroxychloroquine for the main symptoms of primary Sjögren syndrome: dryness, pain, and fatigue." | 5.19 | Effects of hydroxychloroquine on symptomatic improvement in primary Sjögren syndrome: the JOQUER randomized clinical trial. ( Batouche, D; Benessiano, J; Devauchelle-Pensec, V; Dubost, JJ; Furlan, V; Goeb, V; Gottenberg, JE; Hatron, P; Hayem, G; Larroche, C; Le Guern, V; Mariette, X; Morel, J; Perdriger, A; Perrodeau, E; Puéchal, X; Ravaud, P; Rist, S; Saraux, A; Sene, D; Seror, R; Sibilia, J; Zarnitsky, C, 2014) |
| "YFU combined hydroxychloroquine sulfate tablet showed better effects in treating Sjogren's syndrome patients than using Chinese medicine or Western medicine alone." | 5.16 | [Analysis of the clinical efficacy of yiqi fumai injection combined hydroxychloroquine sulfate tablet for treating Sjogren's syndrome]. ( Chen, FY; Wang, H; Xue, B, 2012) |
| "To systematically review and assess the efficacy and safety of hydroxychloroquine (HCQ) for treating primary Sjogren's syndrome (pSS)." | 4.95 | Is hydroxychloroquine effective in treating primary Sjogren's syndrome: a systematic review and meta-analysis. ( Hua, H; Wang, SQ; Wei, P; Zhang, LW, 2017) |
| " In severe cases of keratoconjunctivitis sicca, topical cyclosporine A may be used." | 4.89 | Primary Sjögren syndrome: an update on current pharmacotherapy options and future directions. ( Bové, A; Brito-Zerón, P; Kostov, BA; Ramos-Casals, M; Sisó-Almirall, A, 2013) |
| "Hydroxychloroquine (HCQ) therapy decreased immunoglobulin (Ig) levels in patients with Sjögren syndrome (SS) and rheumatoid arthritis (RA) in previous studies." | 4.12 | Hydroxychloroquine Therapy and Serum Immunoglobulin Levels in Women with IgG Subclass Deficiency and Systemic Lupus Erythematosus, Sjögren Syndrome, and Rheumatoid Arthritis: A Retrospective Study. ( Barton, JC; Bertoli, LF, 2022) |
| "Two patients aged 31 and 42 years were treated with hydroxychloroquine for systemic lupus and Sjogren's syndrome, respectively." | 3.96 | [Drug-induced Sweet's syndrome related to hydroxychloroquine: About 2 cases]. ( Bodard, Q; Carre, D; Chenal, P; Litrowski, N; Midhat, M; Zarnitsky, C, 2020) |
| "To determine whether taking hydroxychloroquine (HCQ) could prevent the development of new-onset diabetes mellitus (DM) among patients with Sjögren syndrome (SS)." | 3.91 | Hydroxychloroquine was associated with reduced risk of new-onset diabetes mellitus in patients with Sjögren syndrome. ( Chen, TH; Chiou, JY; Hung, YM; Lai, TY; Wang, YH; Wei, JC, 2019) |
| "The purpura on both lower extremities had faded at the sixth day after onset and at the third day after hydroxychloroquine treatment." | 3.85 | Primary Sjögren syndrome that initially presented with repeated hypergammaglobulinemic purpura after prolonged sitting: A case report. ( Huang, M; Jiang, W; Liang, D; Liu, Y; Wang, M; Zhang, W; Zhou, Z, 2017) |
| "A 57-year-old woman with systemic lupus erythematosus and Sjögren syndrome presented with blue-grey hyperpigmentation of the face, upper back, and dorsal aspects of the feet after seven years of therapy with hydroxychloroquine." | 3.79 | Hydroxycholoroquine-induced hyperpigmentation. ( Boyd, KP; McLellan, B; Meehan, SA; Mir, A, 2013) |
| " The aim of this report was to draw attention to the localized mucocutaneous bluish-grey hyperpigmentation induced by hydroxychloroquine with a case presentation and a review of the literature." | 3.74 | Hydroxychloroquine-induced hyperpigmentation: a case report. ( Budak, BS; Gurbuz, U; Kacar, C; Melikoglu, M; Melikoglu, MA, 2008) |
| "To determine whether (i) cholinesterase activity is increased in the saliva of patients with primary Sjogren's syndrome (pSS), (ii) increased levels of cholinesterase of lymphocyte origin could interfere with the secretory activity of submandibular acinar cells, and (iii) hydroxychloroquine at therapeutic doses could interfere with cholinesterase activity." | 3.73 | Hydroxychloroquine therapy in patients with primary Sjögren's syndrome may improve salivary gland hypofunction by inhibition of glandular cholinesterase. ( Caulfield, VL; Christmas, SE; Dawson, LJ; Field, AE; Smith, PM; Stanbury, JB, 2005) |
| " A case of psoriatic onychoperiostitis precipitated by hydroxychloroquine therapy is reported." | 3.69 | Recurrent psoriatic onychoperiostitis induced by hydroxychloroquine. ( Cribier, B; Javier, RM; Kuntz, JL; Pflumio, F; Sibilia, J, 1995) |
| "A female patient from the French Antilles developed renal failure due to pure chronic interstitial nephritis six months after the onset of systemic lupus erythematosus (SLE) for which she was taking hydroxychloroquine." | 3.68 | [Lupus, sicca syndrome and chronic interstitial nephritis. Apropos of a case]. ( Blanche, P; Sicard, D, 1992) |
| " We have found that baricitinib might be effective and safe in pSS in a pilot study." | 3.30 | A multi-center, open-label, randomized study to explore efficacy and safety of baricitinib in active primary Sjogren's syndrome patients. ( Bai, W; Leng, X; Li, H; Shi, X; Wei, W; Xu, H; Yang, F; Zeng, X; Zhang, L; Zhang, Y; Zhao, Y, 2023) |
| "Sjögren's Syndrome-related dry eye is a disorder, whose diagnosis may be difficult and mistaken for non-Sjögren's Syndrome-related dry eye." | 2.82 | Dry eye in Sjögren's syndrome - characteristics and therapy. ( Caban, M; Latecka-Krajewska, B; Omulecki, W, 2022) |
| "The rapid spread of the new Coronavirus Disease 2019 (COVID-19) has actually become the newest challenge for the healthcare system since, to date, there is not an effective treatment." | 2.66 | Recent Clinical and Preclinical Studies of Hydroxychloroquine on RNA Viruses and Chronic Diseases: A Systematic Review. ( De Tommasi, N; Faraone, I; Labanca, F; Milella, L; Ponticelli, M, 2020) |
| "Despite restarting olanzapine, her visual hallucinations persisted." | 2.50 | Psychiatric manifestations of primary Sjögren's syndrome: a case report and literature review. ( Andrews, T; D'Cruz, D; Nortley, R; Wong, JK, 2014) |
| "Dry eye affects many individuals worldwide." | 2.47 | Treatment of Sjögren's syndrome-associated dry eye an evidence-based review. ( Adyanthaya, RS; Akpek, EK; Baer, AN; Lindsley, KB; McDonnell, PJ; Swamy, R, 2011) |
| "Sjogren syndrome (SS) and systemic lupus erythematosus (SLE) are both collagen vascular diseases that can be accompanied by Ro antibodies." | 2.43 | Sjögren syndrome and systemic lupus erythematosus are distinct conditions. ( Scheinfeld, N, 2006) |
| "Sjogren's syndrome is an autoimmune exocrinopathy that predominantly affects salivary and lachrymal glands, leading to dry eyes and mouth." | 2.43 | Management of patients presenting with Sjogren's syndrome. ( Venables, PJ, 2006) |
| "Hydroxychloroquine has been successfully applied for the treatment of arthralgias, myalgias and general constitutive symptoms of SS patients." | 2.39 | Antimalarials in Sjögren's syndrome--the Greek experience. ( Manoussakis, MN; Moutsopoulos, HM, 1996) |
| "Hydroxychloroquine (HCQ) is a lysosomotropic agent that is commonly used for treating Sjögren's disease (SjD)." | 1.91 | Salivary gland LAMP3 mRNA expression is a possible predictive marker in the response to hydroxychloroquine in Sjögren's disease. ( Afione, SA; Atsumi, T; Chiorini, JA; Ji, Y; Motta, ACF; Nakamura, H; Noguchi, M; Oliveira, FR; Rocha, EM; Tanaka, T; Warner, BM; Zheng, C, 2023) |
| "Treatment with hydroxychloroquine might not be enough to lower the cardiovascular risk significantly in diabetes patients with Sjögren syndrome." | 1.72 | Sjögren syndrome is a hidden contributor of macrovascular and microvascular complications in patients with type 2 diabetes. ( Leong, PY; Su, YJ; Wang, YH; Wei, JC, 2022) |
| "Annular erythema is one of the cutaneous manifestations of Sjögren's syndrome (SS)." | 1.62 | Efficacy of hydroxychloroquine for treating annular erythema associated with Sjögren's syndrome. ( Amagai, M; Arakawa, H; Miyamoto, J; Murakami, K; Sujino, K; Tanaka, R; Tanese, K; Tanikawa, A, 2021) |
| "Hydroxychloroquine was most frequently used (88." | 1.62 | Clinical features and outcomes from the Singapore Sjögren's syndrome study. ( Charan, N; Kam, JK; Leong, RW; Loh, ZW; Thong, BY, 2021) |
| "There is a lack of information on the role of chronic use of hydroxychloroquine during the SARS-CoV-2 outbreak." | 1.62 | Chronic use of hydroxychloroquine did not protect against COVID-19 in a large cohort of patients with rheumatic diseases in Brazil. ( Abreu, MM; Albuquerque, CP; Araújo, NC; Bacchiega, AB; Bianchi, DV; Bica, B; Bonfa, ED; Borba, EF; Brito, DCSE; de Souza, VA; Duarte, ÂLBP; Fernandes, PR; Ferreira, GA; Gomes, KWP; Guimarães, MP; Junior, LFR; Kakehasi, AM; Klumb, EM; Lacerda, MVG; Lanna, CCD; Marques, CDL; Monticielo, OA; Mota, LMH; Munhoz, GA; Paiva, ES; Pereira, HLA; Pileggi, GS; Pinheiro, MM; Provenza, JR; Reis, APMG; Reis-Neto, ET; Ribeiro, SLE; Sampaio, CSJC; Sampaio, VS; Santo, RCE; Sato, EI; Skare, T; Valim, V; Xavier, RM, 2021) |
| "Rheumatic diseases were IA (60%) and CTD (40%)." | 1.56 | Clinical outcomes of hospitalised patients with COVID-19 and chronic inflammatory and autoimmune rheumatic diseases: a multicentric matched cohort study. ( Alvaro-Gracia, JM; Blanco, R; Carmona, L; Castrejón, I; Fernández Fernández, D; Fernandez-Nebro, A; Galindo, M; Gonzalez-Gay, MA; Lledó, A; Manrique-Arija, S; Martinez-Lopez, D; Mena Vázquez, N; Mera-Varela, A; Pablos, JL; Retuerto, M, 2020) |
| " Univariate and multivariate analysis showed that long-term use of HCQ, menopause, and income were related to sleep quality." | 1.56 | Long-term hydroxychloroquine therapy improves the quality of sleep in patients with primary Sjögren's syndrome: a real-world study. ( Chen, J; Chen, Z; Guan, P; Ran, R; Sun, C, 2020) |
| "Investigations revealed distal renal tubular acidosis with severe metabolic bone disease as an extra-glandular manifestation of primary SS." | 1.56 | Primary Sjogren's syndrome manifesting with distal renal tubular acidosis and severe metabolic bone disease. ( Bhandari, S; Jain, G; Kalra, S; Vasnik, G, 2020) |
| "Autoimmune myelofibrosis is a distinct clinicopathological entity that occurs with autoimmune disorders." | 1.51 | Autoimmune myelofibrosis: a rare haematological involvement in systemic lupus erythematosus. ( Belfeki, N; Declerck, D; Diamantis, S; Shankarasivam, G, 2019) |
| "Hydroxychloroquine (HCQ) is an antimalarial drug that is also used in some dermatologic and rheumatic diseases due to its immunosuppressive actions." | 1.51 | The First Pediatric Case of Acute Generalized Exanthematous Pustulosis Caused by Hydroxychloroquine. ( Barni, S; Giani, T; Liccioli, G; Marrani, E; Mori, F; Simonini, G, 2019) |
| "Retinal involvement in systemic lupus erythematosus (SLE) and Sjögren syndrome (SS) may be subclinical and thus underdiagnosed." | 1.48 | Evidence for the Detection of Subclinical Retinal Involvement in Systemic Lupus Erythematosus and Sjögren Syndrome: A Potential Association with Therapies. ( Aloe, G; Canofari, C; Cesareo, M; Chimenti, MS; Conigliaro, P; Draghessi, G; Nucci, C; Perricone, R; Triggianese, P; Valeri, C, 2018) |
| "Osteomalacia is a rare association with Sjögren's syndrome, which may result from renal disease." | 1.48 | Sjögren's Syndrome Associated with Fanconi's Syndrome and Osteomalacia. ( Gutierrez, JO; Zurita, LA; Zurita, MF, 2018) |
| "Lupus alopecia is usually difficult to treat." | 1.48 | Dramatic effect of hydroxychloroquine on lupus alopecia. ( Igari, S; Yamamoto, T, 2018) |
| "A patient developed toxic epidermal necrolysis (TEN), which was triggered by sun exposure while the patient was on long-term hydroxychloroquine." | 1.35 | Hydroxychloroquine-associated, photo-induced toxic epidermal necrolysis. ( Callaly, EL; FitzGerald, O; Rogers, S, 2008) |
| "The contribution of vitamin B12 deficiency is discussed." | 1.33 | [Recurrent facial palsy, primary Gougerot-Sjögren's syndrome and vitamin B12 deficiency]. ( Andrès, E; Blicklé, JF; Brogard, JM; Noel, E; Rousso, E, 2005) |
| "Although renal tubular acidosis (RTA), secondary to autoimmune interstitial nephritis, develops in a large proportion of patients with Sjögren's syndrome (SS), most of the subjects are asymptomatic." | 1.33 | A primary Sjögren's syndrome patient with distal renal tubular acidosis, who presented with symptoms of hypokalemic periodic paralysis: Report of a case study and review of the literature. ( Celik, Y; Gerenli, M; Pamuk, ON; Soy, M, 2005) |
| "Hydroxychloroquine was prescribed with clinical improvement." | 1.31 | [Primary Gougerot-Sjögren syndrome in a 13-year-old girl]. ( Boutté, P; Michiels, J; Monteilh, C; Sirvent, N; Thouret, MC; Triolo, V, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (5.56) | 18.7374 |
| 1990's | 9 (7.14) | 18.2507 |
| 2000's | 18 (14.29) | 29.6817 |
| 2010's | 57 (45.24) | 24.3611 |
| 2020's | 35 (27.78) | 2.80 |
| Authors | Studies |
|---|---|
| Appelt, LM | 1 |
| Lander, F | 1 |
| Beissert, S | 1 |
| Günther, C | 1 |
| Pileggi, GS | 1 |
| Ferreira, GA | 2 |
| Reis, APMG | 2 |
| Reis-Neto, ET | 1 |
| Abreu, MM | 1 |
| Albuquerque, CP | 1 |
| Araújo, NC | 1 |
| Bacchiega, AB | 1 |
| Bianchi, DV | 1 |
| Bica, B | 1 |
| Bonfa, ED | 1 |
| Borba, EF | 1 |
| Brito, DCSE | 1 |
| Duarte, ÂLBP | 1 |
| Santo, RCE | 1 |
| Fernandes, PR | 1 |
| Guimarães, MP | 1 |
| Gomes, KWP | 1 |
| Kakehasi, AM | 2 |
| Klumb, EM | 1 |
| Lanna, CCD | 1 |
| Marques, CDL | 2 |
| Monticielo, OA | 1 |
| Mota, LMH | 1 |
| Munhoz, GA | 1 |
| Paiva, ES | 1 |
| Pereira, HLA | 1 |
| Provenza, JR | 2 |
| Ribeiro, SLE | 1 |
| Junior, LFR | 1 |
| Sampaio, CSJC | 1 |
| Sampaio, VS | 1 |
| Sato, EI | 2 |
| Skare, T | 1 |
| de Souza, VA | 1 |
| Valim, V | 1 |
| Lacerda, MVG | 1 |
| Xavier, RM | 2 |
| Pinheiro, MM | 1 |
| Consani Fernández, SA | 1 |
| Díaz Cuña, CL | 1 |
| Fernández Rey, L | 1 |
| Rostán Sellanes, S | 1 |
| Maciel Oleggini, G | 1 |
| Facal Castro, JA | 1 |
| Caban, M | 1 |
| Omulecki, W | 1 |
| Latecka-Krajewska, B | 1 |
| Barton, JC | 2 |
| Bertoli, LF | 1 |
| Su, YJ | 1 |
| Leong, PY | 1 |
| Wang, YH | 2 |
| Wei, JC | 2 |
| Hsu, BC | 1 |
| Chen, YH | 1 |
| Lin, CH | 2 |
| Tang, KT | 1 |
| Wang, X | 1 |
| Pang, K | 1 |
| Wang, J | 1 |
| Zhang, B | 1 |
| Liu, Z | 1 |
| Lu, S | 1 |
| Xu, X | 1 |
| Zhu, L | 1 |
| Zhou, Z | 2 |
| Niu, M | 1 |
| Gao, J | 1 |
| Li, J | 1 |
| Zhao, F | 1 |
| Wu, J | 1 |
| Zeng, P | 1 |
| Jiang, Z | 1 |
| Huang, Z | 1 |
| Huang, Y | 1 |
| Xu, H | 2 |
| Chen, C | 1 |
| Ma, W | 1 |
| Henry, K | 1 |
| Deligny, C | 1 |
| Witkowski Durand Viel, P | 1 |
| Morel, J | 2 |
| Guilpain, P | 1 |
| Goulabchand, R | 1 |
| Bai, W | 1 |
| Yang, F | 1 |
| Wei, W | 1 |
| Li, H | 1 |
| Zhang, L | 1 |
| Zhao, Y | 1 |
| Shi, X | 1 |
| Zhang, Y | 1 |
| Zeng, X | 1 |
| Leng, X | 1 |
| Nakamura, H | 1 |
| Tanaka, T | 1 |
| Ji, Y | 1 |
| Zheng, C | 1 |
| Afione, SA | 1 |
| Warner, BM | 1 |
| Oliveira, FR | 1 |
| Motta, ACF | 1 |
| Rocha, EM | 1 |
| Noguchi, M | 1 |
| Atsumi, T | 1 |
| Chiorini, JA | 1 |
| Matsumura, N | 1 |
| Yamamoto, T | 2 |
| Sun, F | 1 |
| Tang, Q | 1 |
| Cheng, W | 1 |
| Xie, X | 1 |
| Li, F | 1 |
| Chen, J | 2 |
| Hamkour, S | 1 |
| van der Heijden, EH | 1 |
| Lopes, AP | 1 |
| Blokland, SLM | 1 |
| Bekker, CPJ | 1 |
| Van Helden-Meeuwsen, CG | 2 |
| Versnel, MA | 3 |
| Kruize, AA | 3 |
| Radstake, TR | 1 |
| Leavis, HL | 1 |
| Hillen, MR | 1 |
| van Roon, JA | 1 |
| Fang, W | 1 |
| Qingqing, Z | 1 |
| Qihui, L | 1 |
| Bing, Z | 1 |
| Xinyue, H | 1 |
| Jie, X | 1 |
| Zhang, A | 1 |
| Chen, S | 1 |
| Lin, R | 1 |
| Chiche, L | 1 |
| Cornec, D | 1 |
| Bodard, Q | 1 |
| Carre, D | 1 |
| Chenal, P | 1 |
| Zarnitsky, C | 2 |
| Midhat, M | 1 |
| Litrowski, N | 1 |
| Basheer, A | 1 |
| Khan, EA | 1 |
| Hashmi, T | 1 |
| Khan, RA | 1 |
| Ahmad, A | 1 |
| Björk, A | 1 |
| Thorlacius, GE | 1 |
| Mofors, J | 2 |
| Richardsdotter Andersson, E | 1 |
| Ivanchenko, M | 1 |
| Tingström, J | 1 |
| James, T | 1 |
| Brokstad, KA | 2 |
| Cox, RJ | 1 |
| Jonsson, R | 2 |
| Kvarnström, M | 2 |
| Wahren-Herlenius, M | 2 |
| Ramos-Casals, M | 3 |
| Brito-Zerón, P | 3 |
| Bombardieri, S | 1 |
| Bootsma, H | 1 |
| De Vita, S | 2 |
| Dörner, T | 2 |
| Fisher, BA | 1 |
| Gottenberg, JE | 4 |
| Hernandez-Molina, G | 1 |
| Kocher, A | 1 |
| Kostov, B | 2 |
| Mandl, T | 1 |
| Ng, WF | 2 |
| Retamozo, S | 2 |
| Seror, R | 3 |
| Shoenfeld, Y | 1 |
| Sisó-Almirall, A | 2 |
| Tzioufas, AG | 1 |
| Vitali, C | 1 |
| Bowman, S | 1 |
| Mariette, X | 4 |
| Zhang, J | 1 |
| Wang, HD | 1 |
| Yang, HJ | 1 |
| Ward, JM | 1 |
| Hess, JN | 1 |
| Davis, LS | 1 |
| Limaye, VS | 1 |
| Cash, K | 1 |
| Smith, C | 1 |
| Koszyca, B | 1 |
| Patel, S | 1 |
| Greenberg, SA | 1 |
| Hissaria, P | 1 |
| Jain, G | 1 |
| Kalra, S | 1 |
| Vasnik, G | 1 |
| Bhandari, S | 1 |
| Dos Reis Neto, ET | 1 |
| de Medeiros Pinheiro, M | 1 |
| da Mota, LMH | 1 |
| Dos Santos Paiva, E | 1 |
| Pileggi, GCS | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Chewing Gum and Exercises of the Tongue, Lip, and Jaw on Salivation, Xerostomia, and Dysphagia in Patients With Sjögren's Syndrome[NCT05680064] | 86 participants (Actual) | Interventional | 2023-01-10 | Completed | |||
| Hydroxychloroquine Assessment of Management Study in Coronary Artery Disease After Angiography.[NCT02874287] | Phase 4 | 35 participants (Actual) | Interventional | 2017-10-08 | Completed | ||
| Randomized, Double-blind, Placebo-controlled Trial of Hydroxychloroquine in Primary Sjögren's Syndrome[NCT00632866] | Phase 3 | 120 participants (Actual) | Interventional | 2008-03-31 | Completed | ||
| Phase 3 Study of Hydroxychloroquine Treatment of Dry Eyes in Patients With Primary Sjögren's Syndrome[NCT01601028] | Phase 3 | 39 participants (Actual) | Interventional | 2011-07-31 | Completed | ||
| Analysis of Hydroxychloroquine Blood Levels in Patients With Primary Sjögren Syndrome and Possible Correlation With the Disease Activity[NCT04546542] | 75 participants (Anticipated) | Observational | 2020-10-01 | Active, not recruiting | |||
| Effect of Pilocarpine in Patients With Xerostomia[NCT02982577] | Phase 4 | 80 participants (Anticipated) | Interventional | 2016-04-30 | Recruiting | ||
| Effects of Hydroxychloroquine on Oral Complaints of Sjögren Patients: a Prospective Sample Study.[NCT00873496] | 30 participants (Actual) | Observational | 2005-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
21 reviews available for hydroxychloroquine and Sicca Syndrome
| Article | Year |
|---|---|
Dry eye in Sjögren's syndrome - characteristics and therapy.
Topics: Dry Eye Syndromes; Humans; Hydroxychloroquine; Lubricant Eye Drops; Sjogren's Syndrome; Tears | 2022 |
Combined use of total glucosides of paeony and hydroxychloroquine in primary Sjögren's syndrome: A systematic review.
Topics: Dry Eye Syndromes; Glucosides; Humans; Hydroxychloroquine; Immunoglobulin A; Immunoglobulin G; Immun | 2023 |
Revisiting hydroxychloroquine and chloroquine for patients with chronic immunity-mediated inflammatory rheumatic diseases.
Topics: Antimalarials; Antiphospholipid Syndrome; Antirheumatic Agents; Arthritis, Rheumatoid; Chloroquine; | 2020 |
Recent Clinical and Preclinical Studies of Hydroxychloroquine on RNA Viruses and Chronic Diseases: A Systematic Review.
Topics: Arthritis, Rheumatoid; Betacoronavirus; Chikungunya Fever; Chikungunya virus; Coronavirus Infections | 2020 |
Treatment strategies for Sjögren's syndrome with childhood onset: a systematic review of the literature.
Topics: Antirheumatic Agents; Azathioprine; Cyclophosphamide; Cyclosporine; Glucocorticoids; Humans; Hydroxy | 2022 |
Is hydroxychloroquine effective in treating primary Sjogren's syndrome: a systematic review and meta-analysis.
Topics: Antirheumatic Agents; Humans; Hydroxychloroquine; Prospective Studies; Randomized Controlled Trials | 2017 |
Primary Sjögren's syndrome.
Topics: Antibodies, Antinuclear; Arthritis, Rheumatoid; Humans; Hydroxychloroquine; Hypergammaglobulinemia; | 2018 |
Emerging drugs for primary Sjögren's syndrome.
Topics: Abatacept; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Clinical Trials as Topic; Drug D | 2019 |
Psychiatric manifestations of primary Sjögren's syndrome: a case report and literature review.
Topics: Antipsychotic Agents; Antirheumatic Agents; Benzodiazepines; Female; Glucocorticoids; Hallucinations | 2014 |
Severe Sensory Neuronopathy in Primary Sjögren Syndrome Resulting in Charcot Arthropathy.
Topics: Aged; Ankle Fractures; Arthropathy, Neurogenic; Electromyography; Female; Follow-Up Studies; Fractur | 2016 |
New Treatment Guidelines for Sjögren's Disease.
Topics: Antirheumatic Agents; Biological Products; Cariostatic Agents; Cost of Illness; Delphi Technique; De | 2016 |
Emerging treatment strategies and potential therapeutic targets in primary Sjögren's syndrome.
Topics: Apoptosis; B-Lymphocytes; Chemokines; Glucocorticoids; Humans; Hydroxychloroquine; Immunosuppressive | 2010 |
Pulmonary amyloidosis in Sjogren's syndrome: a case report and systematic review of the literature.
Topics: Adrenal Cortex Hormones; Adult; Amyloidosis; Anti-Bacterial Agents; Antitubercular Agents; Biopsy; E | 2010 |
Treatment of Sjögren's syndrome-associated dry eye an evidence-based review.
Topics: Administration, Oral; Administration, Topical; Anti-Inflammatory Agents; Dry Eye Syndromes; Evidence | 2011 |
Primary Sjögren syndrome: an update on current pharmacotherapy options and future directions.
Topics: Cyclosporine; Glucocorticoids; Humans; Hydroxychloroquine; Immunosuppressive Agents; Keratoconjuncti | 2013 |
Sjögren syndrome and systemic lupus erythematosus are distinct conditions.
Topics: Humans; Hydroxychloroquine; Lupus Erythematosus, Systemic; Sjogren's Syndrome | 2006 |
Management of patients presenting with Sjogren's syndrome.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Diagnosis, Differential; Glucocortico | 2006 |
Antimalarials in Sjögren's syndrome--the Greek experience.
Topics: Antimalarials; Autoimmunity; Exocrine Glands; Greece; Humans; Hydroxychloroquine; Lymphoma; Sjogren' | 1996 |
Recognition and management of Sjögren's syndrome: strategies for the advanced practice nurse.
Topics: Antirheumatic Agents; Female; Humans; Hydroxychloroquine; Male; Middle Aged; Nursing, Practical; Pre | 2000 |
Management of rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Azathioprine; Chloroquine; Cyc | 1986 |
Ocular manifestations of rheumatic disorders. Natural and iatrogenic.
Topics: Adrenal Cortex Hormones; Arteritis; Arthritis, Juvenile; Arthritis, Rheumatoid; Chloroquine; Conjunc | 1973 |
11 trials available for hydroxychloroquine and Sicca Syndrome
| Article | Year |
|---|---|
A multi-center, open-label, randomized study to explore efficacy and safety of baricitinib in active primary Sjogren's syndrome patients.
Topics: Humans; Hydroxychloroquine; Janus Kinase Inhibitors; Multicenter Studies as Topic; Pilot Projects; P | 2023 |
Safety and Efficacy of Oral Hydroxychloroquine in the Treatment of Ophthalmic Disease Associated with Sjögren's Syndrome.
Topics: Dry Eye Syndromes; Humans; Hydroxychloroquine; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; | 2023 |
[Observation on therapeutic effect of needle-knife for dry mouth and eyes symptoms of primary Sjögren's syndrome].
Topics: Acupuncture Therapy; Humans; Hydroxychloroquine; Sjogren's Syndrome; Tears; Treatment Outcome | 2019 |
Revisiting the JOQUER trial: stratification of primary Sjögren's syndrome and the clinical and interferon response to hydroxychloroquine.
Topics: Antirheumatic Agents; Female; Follow-Up Studies; Humans; Hydroxychloroquine; Interferons; Male; Sjog | 2021 |
Hydroxychloroquine treatment downregulates systemic interferon activation in primary Sjögren's syndrome in the JOQUER randomized trial.
Topics: Adult; Down-Regulation; Enzyme Inhibitors; Female; Gene Expression; Humans; Hydroxychloroquine; Inte | 2020 |
[Analysis of the clinical efficacy of yiqi fumai injection combined hydroxychloroquine sulfate tablet for treating Sjogren's syndrome].
Topics: Adult; Aged; Drugs, Chinese Herbal; Female; Humans; Hydroxychloroquine; Injections; Male; Middle Age | 2012 |
Effects of hydroxychloroquine on symptomatic improvement in primary Sjögren syndrome: the JOQUER randomized clinical trial.
Topics: Adult; Aged; Double-Blind Method; Enzyme Inhibitors; Fatigue; Female; Humans; Hydroxychloroquine; Ma | 2014 |
Effects of hydroxychloroquine on symptomatic improvement in primary Sjögren syndrome: the JOQUER randomized clinical trial.
Topics: Adult; Aged; Double-Blind Method; Enzyme Inhibitors; Fatigue; Female; Humans; Hydroxychloroquine; Ma | 2014 |
Effects of hydroxychloroquine on symptomatic improvement in primary Sjögren syndrome: the JOQUER randomized clinical trial.
Topics: Adult; Aged; Double-Blind Method; Enzyme Inhibitors; Fatigue; Female; Humans; Hydroxychloroquine; Ma | 2014 |
Effects of hydroxychloroquine on symptomatic improvement in primary Sjögren syndrome: the JOQUER randomized clinical trial.
Topics: Adult; Aged; Double-Blind Method; Enzyme Inhibitors; Fatigue; Female; Humans; Hydroxychloroquine; Ma | 2014 |
Effect of Hydroxychloroquine Treatment on Dry Eyes in Subjects with Primary Sjögren's Syndrome: a Double-Blind Randomized Control Study.
Topics: Aged; B-Cell Activating Factor; Blood Sedimentation; Double-Blind Method; Drug Administration Schedu | 2016 |
Effects of hydroxychloroquine on salivary flow rates and oral complaints of Sjögren patients: a prospective sample study.
Topics: Adult; Aged; Burning Mouth Syndrome; Cheilitis; Cholinesterase Inhibitors; Deglutition; Enzyme Inhib | 2010 |
Hydroxychloroquine treatment for primary Sjögren's syndrome: a two year double blind crossover trial.
Topics: Adult; Aged; Blood Sedimentation; Double-Blind Method; Female; Humans; Hydroxychloroquine; Immunoglo | 1993 |
Treatment of primary Sjögren's syndrome with hydroxychloroquine: a retrospective, open-label study.
Topics: Adolescent; Adult; Aged; Antimalarials; Antirheumatic Agents; Child; Female; Humans; Hydroxychloroqu | 1996 |
94 other studies available for hydroxychloroquine and Sicca Syndrome
| Article | Year |
|---|---|
Annular erythematous plaques as manifestation of vasculitis in pediatric Sjögren's syndrome.
Topics: Antirheumatic Agents; Azathioprine; Child; Erythema; Face; Female; Fingers; Humans; Hydroxychloroqui | 2022 |
Chronic use of hydroxychloroquine did not protect against COVID-19 in a large cohort of patients with rheumatic diseases in Brazil.
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Brazil; Chi-Square Dist | 2021 |
Infections in systemic autoimmune diseases.
Topics: Female; Humans; Hydroxychloroquine; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Retro | 2021 |
Hydroxychloroquine Therapy and Serum Immunoglobulin Levels in Women with IgG Subclass Deficiency and Systemic Lupus Erythematosus, Sjögren Syndrome, and Rheumatoid Arthritis: A Retrospective Study.
Topics: Adult; Arthritis, Rheumatoid; Female; Humans; Hydroxychloroquine; IgG Deficiency; Immunoglobulin A; | 2022 |
Sjögren syndrome is a hidden contributor of macrovascular and microvascular complications in patients with type 2 diabetes.
Topics: Aspirin; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Humans; Hydroxychlo | 2022 |
The association between hydroxychloroquine use and future development of systemic lupus erythematosus in patients with primary Sjögren's syndrome.
Topics: Case-Control Studies; Cohort Studies; Humans; Hydroxychloroquine; Lupus Erythematosus, Systemic; Sjo | 2022 |
Microbiota dysbiosis in primary Sjögren's syndrome and the ameliorative effect of hydroxychloroquine.
Topics: Dysbiosis; Female; Gastrointestinal Microbiome; Humans; Hydroxychloroquine; Microbiota; RNA, Ribosom | 2022 |
PI3K/AKT/mTOR Signaling Pathway Is Downregulated by Runzaoling (RZL) in Sjögren's Syndrome.
Topics: Animals; Disease Models, Animal; Down-Regulation; Hydroxychloroquine; Interleukin-17; Mice; Mice, In | 2022 |
[Infections in primary Sjögren's syndrome patients: "Real-life" study of 109 patients from Montpellier university hospital].
Topics: Adult; Aged; Female; Hospitals; Humans; Hydroxychloroquine; Lung; Male; Middle Aged; Retrospective S | 2022 |
Salivary gland LAMP3 mRNA expression is a possible predictive marker in the response to hydroxychloroquine in Sjögren's disease.
Topics: Animals; Chloroquine; Hydroxychloroquine; Lysosomal Membrane Proteins; Mice; Retrospective Studies; | 2023 |
CD123 and MxA expression in a case of annular erythema associated with primary Sjögren's syndrome successfully treated with hydroxychloroquine.
Topics: Erythema; Humans; Hydroxychloroquine; Interleukin-3 Receptor alpha Subunit; Sjogren's Syndrome | 2023 |
Characteristics and treatment responses of immune thrombocytopenia in patients with primary Sjögren syndrome.
Topics: Hemorrhage; Humans; Hydroxychloroquine; Purpura, Thrombocytopenic, Idiopathic; Retrospective Studies | 2023 |
Leflunomide/hydroxychloroquine combination therapy targets type I IFN-associated proteins in patients with Sjögren's syndrome that show potential to predict and monitor clinical response.
Topics: Biomarkers; Humans; Hydroxychloroquine; Interferon Type I; Leflunomide; Leukocytes, Mononuclear; Pro | 2023 |
Mysterious uncoupled clinical symptoms and interferon signature in Sjögren's syndrome: limitations of current approaches for unravelling complexity?
Topics: Antiviral Agents; Humans; Hydroxychloroquine; Interferons; Sjogren's Syndrome | 2020 |
[Drug-induced Sweet's syndrome related to hydroxychloroquine: About 2 cases].
Topics: Adrenal Cortex Hormones; Adult; Diagnosis, Differential; Drug Substitution; Female; Humans; Hydroxyc | 2020 |
Recurrent aseptic meningitis: A rare clinical presentation of Sjogren's syndrome.
Topics: Antibodies, Antinuclear; Antirheumatic Agents; Fatigue; Female; Glucocorticoids; Humans; Hydroxychlo | 2019 |
Viral antigens elicit augmented immune responses in primary Sjögren's syndrome.
Topics: Adult; Aged; Antigens, Viral; Autoantibodies; Female; Humans; Hydroxychloroquine; Immunoglobulin G; | 2020 |
EULAR recommendations for the management of Sjögren's syndrome with topical and systemic therapies.
Topics: Administration, Ophthalmic; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antirh | 2020 |
Targetoid-like Lesions in the Setting of Systemic Lupus Erythematosus: A Case of Rowell Syndrome.
Topics: Adrenal Cortex Hormones; Adult; Antirheumatic Agents; Diagnosis, Differential; Erythema Multiforme; | 2020 |
Inclusion-body myositis and primary Sjögren syndrome: mechanisms for shared etiologies.
Topics: 5'-Nucleotidase; Adult; Autoantibodies; Azathioprine; CD8-Positive T-Lymphocytes; Female; Haplotypes | 2020 |
Primary Sjogren's syndrome manifesting with distal renal tubular acidosis and severe metabolic bone disease.
Topics: Absorptiometry, Photon; Acidosis, Renal Tubular; Adolescent; Antirheumatic Agents; Arthralgia; Bone | 2020 |
Long-term hydroxychloroquine therapy improves the quality of sleep in patients with primary Sjögren's syndrome: a real-world study.
Topics: Female; Humans; Hydroxychloroquine; Quality of Life; Sjogren's Syndrome; Sleep; Sleep Wake Disorders | 2020 |
Clinical outcomes of hospitalised patients with COVID-19 and chronic inflammatory and autoimmune rheumatic diseases: a multicentric matched cohort study.
Topics: Adenosine Monophosphate; Age Factors; Aged; Alanine; Antiviral Agents; Arthritis, Psoriatic; Arthrit | 2020 |
Clinical features and outcomes from the Singapore Sjögren's syndrome study.
Topics: Adult; Arthralgia; Azathioprine; Female; Humans; Hydroxychloroquine; Keratoconjunctivitis Sicca; Mal | 2021 |
[Drug-induced toxidermia in a patient receiving hydroxychloroquine as systemic therapy for primary Gougerot-Sjögren syndrome: a case report].
Topics: Adult; Antirheumatic Agents; Drug Eruptions; Female; Humans; Hydrocortisone; Hydroxychloroquine; Lor | 2021 |
Efficacy of hydroxychloroquine for treating annular erythema associated with Sjögren's syndrome.
Topics: Erythema; Humans; Hydroxychloroquine; Retrospective Studies; Sjogren's Syndrome; Skin Diseases, Gene | 2021 |
High maternal expression of SIGLEC1 on monocytes as a surrogate marker of a type I interferon signature is a risk factor for the development of autoimmune congenital heart block.
Topics: Adult; Antibodies, Antinuclear; Antirheumatic Agents; Autoimmune Diseases; Case-Control Studies; Che | 2017 |
H1N1 vaccination in Sjögren's syndrome triggers polyclonal B cell activation and promotes autoantibody production.
Topics: Antibodies, Viral; Antigens, CD19; Antirheumatic Agents; Autoantibodies; Autoantigens; B-Lymphocytes | 2017 |
Primary Sjögren's syndrome: Extraglandular manifestations and hydroxychloroquine therapy.
Topics: Adult; Antirheumatic Agents; Fatigue; Female; Humans; Hydroxychloroquine; Hypergammaglobulinemia; In | 2017 |
Dramatic effect of hydroxychloroquine on lupus alopecia.
Topics: Administration, Oral; Adult; Alopecia; Antirheumatic Agents; Biopsy; Dermatitis, Atopic; Female; Hum | 2018 |
Hydroxychloroquine-Mediated Cardiotoxicity With a False-Positive
Topics: Aged; Amyloidosis; Antirheumatic Agents; Cardiotoxicity; Echocardiography; Female; Humans; Hydroxych | 2018 |
Primary Sjögren syndrome that initially presented with repeated hypergammaglobulinemic purpura after prolonged sitting: A case report.
Topics: Antirheumatic Agents; Female; Humans; Hydroxychloroquine; Hypergammaglobulinemia; Lower Extremity; M | 2017 |
Sjögren's Syndrome Associated with Fanconi's Syndrome and Osteomalacia.
Topics: Adult; Antibiotics, Antineoplastic; Antirheumatic Agents; Biopsy; Drug Therapy, Combination; Fanconi | 2018 |
Primary Sjogren syndrome diagnosed simultaneously with localized amyloidosis of the lacrimal gland: A case report.
Topics: Amyloidosis; Antirheumatic Agents; Biopsy; Female; Humans; Hydroxychloroquine; Lacrimal Apparatus; M | 2018 |
Evidence for the Detection of Subclinical Retinal Involvement in Systemic Lupus Erythematosus and Sjögren Syndrome: A Potential Association with Therapies.
Topics: Antirheumatic Agents; Case-Control Studies; Female; Humans; Hydroxychloroquine; Immunosuppressive Ag | 2018 |
Athetoid Movements as Initial Manifestation of Primary Sjögren Syndrome.
Topics: Aged; Amines; Anticonvulsants; Athetosis; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Ami | 2018 |
Obstetrical morbidity related to anti-SSA antibodies: Data from a French monocentric retrospective study.
Topics: Adult; Antibodies, Antinuclear; Antiphospholipid Syndrome; Aspirin; Databases, Factual; Female; Fran | 2019 |
Woman in grey: hydroxychloroquine-induced hyperpigmentation.
Topics: Aged, 80 and over; Antirheumatic Agents; Female; Humans; Hydroxychloroquine; Hyperpigmentation; Lupu | 2018 |
Autoimmune myelofibrosis: a rare haematological involvement in systemic lupus erythematosus.
Topics: Adult; Anti-Inflammatory Agents; Antiphospholipid Syndrome; Antirheumatic Agents; Autoimmune Disease | 2019 |
Risk of Parkinson disease in Sjögren syndrome administered ineffective immunosuppressant therapies: A nationwide population-based study.
Topics: Adult; Aged; Anti-Inflammatory Agents; Antirheumatic Agents; Comorbidity; Female; Humans; Hydroxychl | 2019 |
Hydroxychloroquine Retinal Toxicity.
Topics: Antirheumatic Agents; Color Vision Defects; Female; Humans; Hydroxychloroquine; Lupus Erythematosus, | 2019 |
The First Pediatric Case of Acute Generalized Exanthematous Pustulosis Caused by Hydroxychloroquine.
Topics: Acute Generalized Exanthematous Pustulosis; Antirheumatic Agents; Child; Female; Histamine Antagonis | 2019 |
Treatment of spontaneous corneal perforation secondary to undiagnosed Sjögren's syndrome using regenerating agent and autologous serum eye drops.
Topics: Administration, Ophthalmic; Aged; Bandages; Contact Lenses; Corneal Perforation; Corneal Transplanta | 2021 |
Hydroxychloroquine was associated with reduced risk of new-onset diabetes mellitus in patients with Sjögren syndrome.
Topics: Adult; Aged; Antirheumatic Agents; Databases, Factual; Diabetes Mellitus; Female; Glucose; Humans; H | 2019 |
[Connective tissue diseases: news in therapy, role of biologics agents].
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; B-Lymphocytes; Connective Tissue Diseases | 2013 |
[Effect of prescriptions replenishing vital essence, tonifying Qi and activating blood on TNF-alpha, IL-1beta expressions in serum and submaxillary gland of NOD mice with Sjogren's syndrome].
Topics: Animals; Antirheumatic Agents; Drug Administration Schedule; Drug Therapy, Combination; Enzyme-Linke | 2013 |
Salivary and serum B-cell activating factor (BAFF) levels after hydroxychloroquine treatment in primary Sjögren's syndrome.
Topics: Adult; B-Cell Activating Factor; Enzyme Inhibitors; Female; Humans; Hydroxychloroquine; Male; Middle | 2013 |
Hydroxycholoroquine-induced hyperpigmentation.
Topics: Antirheumatic Agents; Female; Foot; Humans; Hydroxychloroquine; Hyperpigmentation; Lupus Erythematos | 2013 |
Effect of hydroxychloroquine on the lipid profile of patients with Sjögren syndrome.
Topics: Aged; Antirheumatic Agents; Atherosclerosis; Dyslipidemias; Female; Humans; Hydroxychloroquine; Lipi | 2014 |
[Astragalus polysaccharides improved the cardiac function in Sjögren's syndrome model rats based on keap 1-Nrf2/ARE signaling pathway: a mechanism exploration].
Topics: Animals; Astragalus Plant; Blotting, Western; Carboxylic Ester Hydrolases; Heme Oxygenase-1; Hydroxy | 2014 |
Validation of the colour difference plot scoring system analysis of the 103 hexagon multifocal electroretinogram in the evaluation of hydroxychloroquine retinal toxicity.
Topics: Adolescent; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Electroretinography; False Pos | 2014 |
Autoimmune haemolytic anaemia as an initial presentation of primary Sjögren syndrome.
Topics: Adult; Anemia, Hemolytic, Autoimmune; Anti-Inflammatory Agents; Antirheumatic Agents; Blood Volume; | 2014 |
Images in clinical medicine. Acute generalized exanthematous pustulosis.
Topics: Acute Generalized Exanthematous Pustulosis; Female; Humans; Hydroxychloroquine; Middle Aged; Sjogren | 2015 |
How are we treating our systemic patients with primary Sjögren syndrome? Analysis of 1120 patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Glucocorticoids; Humans; Hydroxychloroquine; Imm | 2015 |
Effects of Multi-glycosides of Tripterygium wilfordiion in the Treatment of Sjögren's Syndrome in the Non-obese Diabetic Mouse Model.
Topics: Animals; Antibodies, Antinuclear; Body Weight; CD4 Lymphocyte Count; Disease Models, Animal; Female; | 2015 |
Sjögren's syndrome associated with protein losing gastroenteropathy manifested by intestinal lymphangiectasia successfully treated with prednisolone and hydroxychloroquine.
Topics: Adult; Anti-Inflammatory Agents; Antirheumatic Agents; Female; Humans; Hydroxychloroquine; Lymphangi | 2015 |
Effect of Chinese herbal medicines for nourishing yin, supplementing qi, and activating blood on reproductive endocrine activity and immune functions in patients with primary Sjogren's syndrome.
Topics: Adult; Blood Sedimentation; Drugs, Chinese Herbal; Enzyme-Linked Immunosorbent Assay; Estradiol; Fem | 2015 |
Sjögren Sensory Neuronopathy (Sjögren Ganglionopathy): Long-Term Outcome and Treatment Response in a Series of 13 Cases.
Topics: Adrenal Cortex Hormones; Adult; Aged; Cyclophosphamide; Disability Evaluation; Enzyme Inhibitors; Fe | 2016 |
Thrombotic thrombocytopenic purpura in a new onset lupus patient?
Topics: Adult; Anemia, Hemolytic; Autoantibodies; Blood Platelets; Codeine; Cyclophosphamide; Female; Humans | 2017 |
Hydroxychloroquine-induced hyperpigmentation: a case report.
Topics: Antimalarials; Female; Humans; Hydroxychloroquine; Hyperpigmentation; Middle Aged; Sjogren's Syndrom | 2008 |
Treatment of sicca symptoms with hydroxychloroquine in patients with Sjogren's syndrome.
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Autoantibodies; Carrier Proteins; Female; Huma | 2009 |
Systemic vasculitis developing after hydroxychloroquine interruption in a patient with Sjögren's syndrome.
Topics: Drug Administration Schedule; Female; Humans; Hydroxychloroquine; Lymphoma, B-Cell, Marginal Zone; M | 2010 |
Spectral-domain optical coherence tomography and adaptive optics may detect hydroxychloroquine retinal toxicity before symptomatic vision loss.
Topics: Antirheumatic Agents; Female; Fluorescein Angiography; Humans; Hydroxychloroquine; Lupus Erythematos | 2009 |
Articular manifestations in primary Sjögren's syndrome: clinical significance and prognosis of 188 patients.
Topics: Adult; Aged; Antirheumatic Agents; Cohort Studies; Female; France; Humans; Hydroxychloroquine; Joint | 2010 |
Hydroxychloroquine improves dry eye symptoms of patients with primary Sjogren's syndrome.
Topics: Adult; Aged; B-Cell Activating Factor; Biomarkers; Female; Humans; Hydroxychloroquine; Keratoconjunc | 2011 |
Pulmonary amyloidosis in Sjögren's syndrome: a rare diagnosis for nodular lung lesions.
Topics: Amyloid; Amyloidosis; Antirheumatic Agents; Azathioprine; Coloring Agents; Congo Red; Drug Therapy, | 2009 |
Retinopathy due to antimalarial drugs in patients with connective tissue diseases: are they so innocent? A single center retrospective study.
Topics: Adolescent; Adult; Aged; Antimalarials; Arthritis, Rheumatoid; Chi-Square Distribution; Chloroquine; | 2010 |
Rituximab and lupus interstitial lung disease: friend or foe?
Topics: Adult; Antibodies, Monoclonal, Murine-Derived; Antirheumatic Agents; Drug Therapy, Combination; Dysp | 2011 |
A case of primary Sjögren's syndrome presenting primarily with central nervous system vasculitic involvement.
Topics: Adult; Angiography, Digital Subtraction; Azathioprine; Brain; Central Nervous System Diseases; Diagn | 2012 |
Primary sjögren syndrome manifested as localized cutaneous nodular amyloidosis.
Topics: Aged; Amyloidosis; Antirheumatic Agents; Azathioprine; Female; Humans; Hydroxychloroquine; Immunohis | 2011 |
Hypokalemic paralysis in a girl with dental and renal calculi. Distal renal tubular acidosis (RTA).
Topics: Acidosis, Renal Tubular; Adolescent; Child; Child, Preschool; Dental Calculus; Dental Restoration, P | 2013 |
Effects of total glucosides of paeony for delaying onset of Sjogren's syndrome: an animal study.
Topics: Animals; Autoantigens; Disease Models, Animal; Enzyme Inhibitors; Female; Gene Expression Profiling; | 2013 |
Critical hypokalemic renal tubular acidosis due to Sjögren's syndrome: association with the purported immune stimulant echinacea.
Topics: Acidosis, Renal Tubular; Adjuvants, Immunologic; Adult; Antirheumatic Agents; Citrates; Echinacea; E | 2003 |
Assessing hydroxychloroquine toxicity by the multifocal ERG.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Electrooculography; Electroretinography; Humans; | 2004 |
Hydroxychloroquine therapy in patients with primary Sjögren's syndrome may improve salivary gland hypofunction by inhibition of glandular cholinesterase.
Topics: Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Cholinesterases; Dose-Response Relationsh | 2005 |
[Recurrent facial palsy, primary Gougerot-Sjögren's syndrome and vitamin B12 deficiency].
Topics: Adult; Anti-Inflammatory Agents; Antirheumatic Agents; Electromyography; Facial Paralysis; Female; H | 2005 |
A primary Sjögren's syndrome patient with distal renal tubular acidosis, who presented with symptoms of hypokalemic periodic paralysis: Report of a case study and review of the literature.
Topics: Acidosis, Renal Tubular; Adult; Antirheumatic Agents; Diagnosis, Differential; Drug Therapy, Combina | 2005 |
Annular erythema of Sjögren's syndrome.
Topics: Adult; Dermatologic Agents; Erythema; Female; Humans; Hydroxychloroquine; Lupus Erythematosus, Syste | 2006 |
Detection of early hydroxychloroquine retinal toxicity enhanced by ring ratio analysis of multifocal electroretinography.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Child; Cros | 2007 |
Preventive effect of Ophiopogon japonicus polysaccharides on an autoallergic mouse model for Sjogren's syndrome by regulating the Th1/Th2 cytokine imbalance.
Topics: Animals; Autoantigens; Autoimmune Diseases; Body Weight; Cytokines; Disease Models, Animal; Drinking | 2007 |
Hydroxychloroquine-associated, photo-induced toxic epidermal necrolysis.
Topics: Adult; Antirheumatic Agents; Diagnosis, Differential; Female; Humans; Hydroxychloroquine; Sjogren's | 2008 |
[Thrombopenia secondary to hydroxychloroquine].
Topics: Adult; Female; Humans; Hydroxychloroquine; Sjogren's Syndrome; Thrombocytopenia | 1994 |
Astasia-abasia revealing a primary Sjögren's syndrome.
Topics: Brain; Conversion Disorder; Female; Humans; Hydroxychloroquine; Immunoglobulin G; Immunoglobulins; M | 1993 |
[Changes in taste and smell caused by hydroxychloroquine].
Topics: Adult; Antirheumatic Agents; Depression, Chemical; Dysgeusia; Humans; Hydroxychloroquine; Male; Sjog | 1996 |
Recurrent psoriatic onychoperiostitis induced by hydroxychloroquine.
Topics: Female; Humans; Hydroxychloroquine; Middle Aged; Nail Diseases; Periostitis; Psoriasis; Recurrence; | 1995 |
Hydroxychloroquine treatment for primary Sjögren's syndrome: its effect on salivary and serum inflammatory markers.
Topics: Antirheumatic Agents; Biomarkers; Female; Follow-Up Studies; Humans; Hyaluronic Acid; Hydroxychloroq | 1999 |
Multicentric reticulohistiocytosis associated with Sjögren's syndrome.
Topics: Anti-Inflammatory Agents; Antirheumatic Agents; Female; Histiocytosis, Non-Langerhans-Cell; Humans; | 2000 |
[Primary Gougerot-Sjögren syndrome in a 13-year-old girl].
Topics: Adolescent; Antirheumatic Agents; Biopsy; Female; Humans; Hydroxychloroquine; Parotitis; Recurrence; | 2002 |
[Lupus, sicca syndrome and chronic interstitial nephritis. Apropos of a case].
Topics: Adult; Female; Humans; Hydroxychloroquine; Kidney Failure, Chronic; Lupus Erythematosus, Systemic; N | 1992 |
Treatment of primary Sjögren's syndrome with hydroxychloroquine.
Topics: Autoantibodies; Blood Sedimentation; Hemoglobins; Humans; Hydroxychloroquine; Immunoglobulins; Parap | 1988 |
[Primary Gougerot-Sjögren syndrome. Favourable effect of a fundamental treatment with hydroxychloroquine on biological anomalies].
Topics: Female; Humans; Hydroxychloroquine; Sjogren's Syndrome; Time Factors | 1988 |
[Primary Gougerot-Sjögren syndrome with necrotizing polymyositis: favorable effect of hydroxychloroquine].
Topics: Female; Humans; Hydroxychloroquine; Middle Aged; Myositis; Sjogren's Syndrome | 1987 |
Sjögren's syndrome: treatment with D-penicillamine and hydroxychloroquine.
Topics: Adult; Aged; Female; Humans; Hydroxychloroquine; Middle Aged; Penicillamine; Sjogren's Syndrome | 1985 |
[Treatment of Goujerot-Sjogren syndrome].
Topics: Antimalarials; Female; Glucocorticoids; Humans; Hydroxychloroquine; Injections; Keratoconjunctivitis | 1970 |