Page last updated: 2024-10-28

hydroxychloroquine and Reperfusion Injury

hydroxychloroquine has been researched along with Reperfusion Injury in 3 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
" The aim of the present study was to determine the neuroprotective effects of hydroxychloroquine (HCQ) and the timing of its administration in cerebral ischemia/reperfusion (I/R) in rats."8.31Pre-treatment or post-treatment with hydroxychloroquine demonstrates neuroprotective effects in cerebral ischemia/reperfusion. ( Babataheri, S; Malekinejad, H; Mosarrezaii, A; Soraya, H, 2023)
" The aim of the present study was to determine the neuroprotective effects of hydroxychloroquine (HCQ) and the timing of its administration in cerebral ischemia/reperfusion (I/R) in rats."4.31Pre-treatment or post-treatment with hydroxychloroquine demonstrates neuroprotective effects in cerebral ischemia/reperfusion. ( Babataheri, S; Malekinejad, H; Mosarrezaii, A; Soraya, H, 2023)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's2 (66.67)2.80

Authors

AuthorsStudies
Babataheri, S3
Malekinejad, H3
Mosarrezaii, A3
Soraya, H3
Zhang, S1
Zhang, Q1
Wang, F1
Guo, X1
Liu, T1
Zhao, Y1
Gu, B1
Chen, H1
Li, Y1
Tang, TT1
Lv, LL1
Pan, MM1
Wen, Y1
Wang, B1
Li, ZL1
Wu, M1
Wang, FM1
Crowley, SD1
Liu, BC1

Other Studies

3 other studies available for hydroxychloroquine and Reperfusion Injury

ArticleYear
Pre-treatment or post-treatment with hydroxychloroquine demonstrates neuroprotective effects in cerebral ischemia/reperfusion.
    Fundamental & clinical pharmacology, 2023, Volume: 37, Issue:3

    Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Brain Ischemia; Hydroxychloroquine; Infarction; N

2023
Pre-treatment or post-treatment with hydroxychloroquine demonstrates neuroprotective effects in cerebral ischemia/reperfusion.
    Fundamental & clinical pharmacology, 2023, Volume: 37, Issue:3

    Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Brain Ischemia; Hydroxychloroquine; Infarction; N

2023
Pre-treatment or post-treatment with hydroxychloroquine demonstrates neuroprotective effects in cerebral ischemia/reperfusion.
    Fundamental & clinical pharmacology, 2023, Volume: 37, Issue:3

    Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Brain Ischemia; Hydroxychloroquine; Infarction; N

2023
Pre-treatment or post-treatment with hydroxychloroquine demonstrates neuroprotective effects in cerebral ischemia/reperfusion.
    Fundamental & clinical pharmacology, 2023, Volume: 37, Issue:3

    Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Brain Ischemia; Hydroxychloroquine; Infarction; N

2023
Pre-treatment or post-treatment with hydroxychloroquine demonstrates neuroprotective effects in cerebral ischemia/reperfusion.
    Fundamental & clinical pharmacology, 2023, Volume: 37, Issue:3

    Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Brain Ischemia; Hydroxychloroquine; Infarction; N

2023
Pre-treatment or post-treatment with hydroxychloroquine demonstrates neuroprotective effects in cerebral ischemia/reperfusion.
    Fundamental & clinical pharmacology, 2023, Volume: 37, Issue:3

    Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Brain Ischemia; Hydroxychloroquine; Infarction; N

2023
Pre-treatment or post-treatment with hydroxychloroquine demonstrates neuroprotective effects in cerebral ischemia/reperfusion.
    Fundamental & clinical pharmacology, 2023, Volume: 37, Issue:3

    Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Brain Ischemia; Hydroxychloroquine; Infarction; N

2023
Pre-treatment or post-treatment with hydroxychloroquine demonstrates neuroprotective effects in cerebral ischemia/reperfusion.
    Fundamental & clinical pharmacology, 2023, Volume: 37, Issue:3

    Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Brain Ischemia; Hydroxychloroquine; Infarction; N

2023
Pre-treatment or post-treatment with hydroxychloroquine demonstrates neuroprotective effects in cerebral ischemia/reperfusion.
    Fundamental & clinical pharmacology, 2023, Volume: 37, Issue:3

    Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Brain Ischemia; Hydroxychloroquine; Infarction; N

2023
Hydroxychloroquine inhibiting neutrophil extracellular trap formation alleviates hepatic ischemia/reperfusion injury by blocking TLR9 in mice.
    Clinical immunology (Orlando, Fla.), 2020, Volume: 216

    Topics: Animals; Disease Models, Animal; Extracellular Traps; Hydroxychloroquine; Liver; Male; Mice; Mice, I

2020
Hydroxychloroquine attenuates renal ischemia/reperfusion injury by inhibiting cathepsin mediated NLRP3 inflammasome activation.
    Cell death & disease, 2018, 03-02, Volume: 9, Issue:3

    Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Cathepsin B; Cathepsin L; Cell Line; Cell Su

2018