Page last updated: 2024-10-28

hydroxychloroquine and Recrudescence

hydroxychloroquine has been researched along with Recrudescence in 69 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Research Excerpts

ExcerptRelevanceReference
"Previous studies have shown the effect of hydroxychloroquine in the treatment and prevention of recurrence of brucellosis."9.51Combination of doxycycline, streptomycin and hydroxychloroquine for short-course treatment of brucellosis: a single-blind randomized clinical trial. ( Emami, K; Hashmi, SH; Majzoobi, MM; Soltanian, AR, 2022)
"Glucocorticoid (GC)-dependent, colchicine-resistant idiopathic recurrent pericarditis (IRP) remains a clinical challenge."7.96Hydroxychloroquine for colchicine-resistant glucocorticoid-dependent idiopathic recurrent pericarditis: A pilot observational prospective study. ( Antonatou, K; Antonopoulos, AS; Hadziyannis, E; Lazaros, G; Lazarou, E; Leontsinis, I; Ritis, K; Simantiris, S; Skendros, P; Tousoulis, D; Vassilopoulos, D; Vlachopoulos, C, 2020)
" A case of psoriatic onychoperiostitis precipitated by hydroxychloroquine therapy is reported."7.69Recurrent psoriatic onychoperiostitis induced by hydroxychloroquine. ( Cribier, B; Javier, RM; Kuntz, JL; Pflumio, F; Sibilia, J, 1995)
"High-dose hydroxychloroquine is rarely used in the treatment of porphyria cutanea tarda (PCT)."7.68High-dose hydroxychloroquine treatment of porphyria cutanea tarda. ( Petersen, CS; Thomsen, K, 1992)
"Hydroxychloroquine (HCQ) is an anti-rheumatic drug commonly used in the treatment of rheumatoid arthritis and systemic lupus erythematosus."6.84Hydroxychloroquine for the prevention of recurrent cardiovascular events in myocardial infarction patients: rationale and design of the OXI trial. ( Eklund, KK; Hartman, O; Kovanen, PT; Lehtonen, J; Sinisalo, J, 2017)
" Studies included were trials in which: (1) the participants were classified as having GCA by the 1990 ACR criteria or biopsy proven disease; (2) parallel-group randomised control of at least 16 weeks duration had been conducted with at least 20 participants; (3) the design included either alternative adjunct immunosuppressant regimens, alternative GCs dosing or routes of administration; and (4) outcome data was included on either relapse rates or rates of infection."6.50Prednisolone combined with adjunctive immunosuppression is not superior to prednisolone alone in terms of efficacy and safety in giant cell arteritis: meta-analysis. ( Loke, YK; MacGregor, AJ; Watts, RA; Yates, M, 2014)
"Previous studies have shown the effect of hydroxychloroquine in the treatment and prevention of recurrence of brucellosis."5.51Combination of doxycycline, streptomycin and hydroxychloroquine for short-course treatment of brucellosis: a single-blind randomized clinical trial. ( Emami, K; Hashmi, SH; Majzoobi, MM; Soltanian, AR, 2022)
"Though autoimmune disorders and prolactinoma were reported in GM, a coexisting condition of SLE, prolactinoma, and granulomatous mastitis has rarely been observed in one patient."5.40An SLE patient with prolactinoma and recurrent granulomatous mastitis successfully treated with hydroxychloroquine and bromocriptine. ( Shi, TY; Yang, YJ; Zhang, FC; Zhang, LN, 2014)
"In 1990 the Utrecht rheumatoid arthritis cohort study group started a clinical trial in which patients with recent onset of rheumatoid arthritis (<1 year) were randomised into four treatment groups: hydroxychloroquine (n = 169); intramuscular gold (n = 163); methotrexate (n = 166); and pyramid (n = 64)."5.11A good response to early DMARD treatment of patients with rheumatoid arthritis in the first year predicts remission during follow up. ( Bijlsma, JW; Blaauw, AA; Haanen, HC; Jacobs, JW; Schenk, Y; van Albada-Kuipers, GA; Verstappen, SM, 2005)
"Recurrences of COVID-19 were observed in a patient with long-term usage of hydroxychloroquine, leflunomide, and glucocorticoids due to her 30-year history of rheumatoid arthritis (RA)."5.05A complex COVID-19 case with rheumatoid arthritis treated with tocilizumab. ( Cai, S; Dong, L; Li, M; Sun, W, 2020)
" Hydroxychloroquine and other ordinary antirheumatic drugs slow down or may even prevent the progression of palindromic rheumatism into chronic rheumatoid arthritis."4.90[Palindromic rheumatism or incipient rheumatoid arthritis--chances of drug therapy]. ( Julkunen, H, 2014)
"A morning standard dose of 250 mcg tetracosactide (Synacthen test) was given in 25 consecutive patients (13 rheumatoid arthritis, 2 psoriatic arthritis, 5 systemic lupus erythematosus, 2 dermatomyositis, 1 systemic sclerosis, 2 temporal arteritis) at the time of relapse upon small reductions (1-2 mg daily) of low prednisolone dose (<7."4.12Impaired adrenal cortex reserve in patients with rheumatic and musculoskeletal diseases who relapse upon tapering of low glucocorticoid dose. ( Filippa, MG; Panopoulos, S; Sfikakis, PP; Spanos, E; Spanos, G; Tektonidou, MG; Yavropoulou, MP, 2022)
"Glucocorticoid (GC)-dependent, colchicine-resistant idiopathic recurrent pericarditis (IRP) remains a clinical challenge."3.96Hydroxychloroquine for colchicine-resistant glucocorticoid-dependent idiopathic recurrent pericarditis: A pilot observational prospective study. ( Antonatou, K; Antonopoulos, AS; Hadziyannis, E; Lazaros, G; Lazarou, E; Leontsinis, I; Ritis, K; Simantiris, S; Skendros, P; Tousoulis, D; Vassilopoulos, D; Vlachopoulos, C, 2020)
" Renewed remission was obtained with additional infliximab, and was maintained with azathioprine for 12 months before the patient again presented with symmetrical polyarthritis."3.73[Symmetric polyarthritis in a patient with Churg-Strauss syndrome]. ( Aries, PM; Reinhold-Keller, E, 2005)
" It was diagnosed to be a case of palindromic rheumatism clinically and treated with hydroxychloroquine."3.71Palindromic rheumatism. ( Singhal, S; Zahid, M, 2002)
" A case of psoriatic onychoperiostitis precipitated by hydroxychloroquine therapy is reported."3.69Recurrent psoriatic onychoperiostitis induced by hydroxychloroquine. ( Cribier, B; Javier, RM; Kuntz, JL; Pflumio, F; Sibilia, J, 1995)
"High-dose hydroxychloroquine is rarely used in the treatment of porphyria cutanea tarda (PCT)."3.68High-dose hydroxychloroquine treatment of porphyria cutanea tarda. ( Petersen, CS; Thomsen, K, 1992)
"Hydroxychloroquine (HCQ) is an anti-rheumatic drug commonly used in the treatment of rheumatoid arthritis and systemic lupus erythematosus."2.84Hydroxychloroquine for the prevention of recurrent cardiovascular events in myocardial infarction patients: rationale and design of the OXI trial. ( Eklund, KK; Hartman, O; Kovanen, PT; Lehtonen, J; Sinisalo, J, 2017)
"Oral prednisone alone was used in 50 of the 59 patients (mean initial dose 1 mg/kg body weight/day)."2.70Treatment of severe immune thrombocytopenia associated with systemic lupus erythematosus: 59 cases. ( Arnal, C; Bierling, P; Godeau, B; Hachulla, E; Léone, J; Papo, T; Piette, JC; Roudot-Thoraval, F; Schaeffer, A; Taillan, B, 2002)
"After the first discharge, she got a recurrence of COVID-19 during her home isolation, and then returned to hospital and continued the previous therapy."2.66Successful recovery of recurrence of positive SARS-CoV-2 RNA in COVID-19 patient with systemic lupus erythematosus: a case report and review. ( Cao, J; Fan, L; He, F; Hu, K; Lei, M; Luo, Q; Qin, S; Shao, X; Yang, L; Yu, N, 2020)
" Studies included were trials in which: (1) the participants were classified as having GCA by the 1990 ACR criteria or biopsy proven disease; (2) parallel-group randomised control of at least 16 weeks duration had been conducted with at least 20 participants; (3) the design included either alternative adjunct immunosuppressant regimens, alternative GCs dosing or routes of administration; and (4) outcome data was included on either relapse rates or rates of infection."2.50Prednisolone combined with adjunctive immunosuppression is not superior to prednisolone alone in terms of efficacy and safety in giant cell arteritis: meta-analysis. ( Loke, YK; MacGregor, AJ; Watts, RA; Yates, M, 2014)
"A minority of patients who acquire acute Q fever will subsequently develop chronic Q fever endocarditis, which often manifests in valvular insufficiency."2.49Cardiac manifestations of Q fever infection: case series and a review of the literature. ( Farivar, RS; Gunn, TM; Raz, GM; Turek, JW, 2013)
"Linear lupus panniculitis of the scalp presenting as alopecia along Blaschko's lines had so far been reported exclusively in five East Asians."2.48Linear lupus panniculitis of the scalp presenting as alopecia along Blaschko's lines: a distinct variant of lupus panniculitis in East Asians? ( Chen, YA; Hsu, CK; Lee, JY; Yang, CC, 2012)
"Six cases of cheilitis granulomatosa, a rare inflammatory disorder of unknown origin, are reported."2.38Cheilitis granulomatosa: report of six cases and review of the literature. ( Allen, CM; Camisa, C; Hamzeh, S; Stephens, L, 1990)
"There were neither recurrences nor relevant major adverse effects in all the five KFD cases treated with hydroxychloroquine."1.51Pediatric Kikuchi-Fujimoto disease: A clinicopathologic study and the therapeutic effects of hydroxychloroquine. ( Chen, YY; Chiou, YH; Huang, HH; Huang, YF; Lee, HS; Lin, YC; Liu, PY; Nong, BR, 2019)
"SDC measurement decreases the risk for disease-related events, potentially through more optimal dosing or improved compliance."1.48The effect of measuring serum doxycycline concentrations on clinical outcomes during treatment of chronic Q fever. ( Bleeker-Rovers, CP; de Regt, MJA; Hoepelman, AIM; Kampschreur, LM; Oosterheert, JJ; van Roeden, SE; Vermeulen Windsant, A; Wever, PC, 2018)
"Cancer recurrence after initial diagnosis and treatment is a major cause of breast cancer (BC) mortality, which results from the metastatic outbreak of dormant tumour cells."1.48Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence. ( Green, JE; Hunter, KW; Nini, R; Vera-Ramirez, L; Vodnala, SK, 2018)
"Hydroxychloroquine treatment significantly decreased (p < 0."1.48Immunomodulatory effects of hydroxychloroquine on Th1/Th2 balance in women with repeated implantation failure. ( Ghaffari Novin, M; Ghasemnejad, T; Ghasemnejad-Berenji, H; Ghasemnejad-Berenji, M; Hajshafiha, M; Hashemi, SM; Ilkhanizadeh, B; Nazarian, H; Sadeghpour, S, 2018)
"malariae infection with clinical recrudescence after directly observed administration of artemether/lumefantrine."1.46Genomic Characterization of Recrudescent Plasmodium malariae after Treatment with Artemether/Lumefantrine. ( Anstey, NM; Auburn, S; Berriman, M; Huang, GKL; Marfurt, J; Marr, I; Newbold, CI; Otto, TD; Price, RN; Rutledge, GG; Sanders, M; White, NJ, 2017)
"Last, we show that the recurrence rate of an adverse pregnancy outcome persisted at 30% despite treatment intervention."1.42Chronic histiocytic intervillositis: outcome, associated diseases and treatment in a multicenter prospective study. ( Botta, A; Bucourt, M; Carbillon, L; Chollet-Martin, S; Chudzinski, A; Cornelis, F; Costedoat-Chalumeau, N; De Carolis, S; Emmanuelli, V; Fain, O; Hachulla, E; Masseau, A; Mekinian, A; Montestruc, F; Nicaise, P; Revaux, A; Subtil, D; Theulin, A, 2015)
"Juvenile systemic lupus erythematosus (JSLE) is a rare multisystem autoimmune disease with broad heterogeneity of clinical manifestations."1.42[Juvenile systemic lupus erythematosus with unusual manifestation of lupus-associated panniculitis]. ( Hashemie, H; Hoff, NP; Homey, B; Klossowski, N; Meller, S; Neubert, J; Oommen, PT; Reifenberger, J, 2015)
"Though autoimmune disorders and prolactinoma were reported in GM, a coexisting condition of SLE, prolactinoma, and granulomatous mastitis has rarely been observed in one patient."1.40An SLE patient with prolactinoma and recurrent granulomatous mastitis successfully treated with hydroxychloroquine and bromocriptine. ( Shi, TY; Yang, YJ; Zhang, FC; Zhang, LN, 2014)
"Most patients had at least one recurrence (18/23, 78%)."1.39Long-term outcome in idiopathic granulomatous mastitis: a western multicentre study. ( Cabane, J; Chiche, L; Costedoat-Chalumeau, N; Cottereau, A; De Faucal, P; Graveleau, J; Hachulla, E; Hamidou, M; Hello, M; Lavigne, C; Néel, A; Rondeau-Lutz, M; Seiberras, S; Tournemaine, N, 2013)
"Six years later, she developed right flank pain."1.39Simultaneous intrahepatic and subgaleal hemorrhage in antiphospholipid syndrome following anticoagulation therapy. ( Baek, YH; Cho, DS; Chung, WT; Han, SY; Kang, SH; Lee, SW; Park, IC, 2013)
"The onset of facial palsy has been linked with Gougerot-Sjögren's syndrome."1.33[Recurrent facial palsy, primary Gougerot-Sjögren's syndrome and vitamin B12 deficiency]. ( Andrès, E; Blicklé, JF; Brogard, JM; Noel, E; Rousso, E, 2005)
"Prednisone was used at a starting dose from about 0."1.33Muscle involvement in sarcoidosis: a retrospective and followup studies. ( Bardin, T; Berenbaum, F; Fayad, F; Lioté, F; Orcel, P, 2006)
"Hydroxychloroquine was prescribed with clinical improvement."1.31[Primary Gougerot-Sjögren syndrome in a 13-year-old girl]. ( Boutté, P; Michiels, J; Monteilh, C; Sirvent, N; Thouret, MC; Triolo, V, 2002)

Research

Studies (69)

TimeframeStudies, this research(%)All Research%
pre-19904 (5.80)18.7374
1990's9 (13.04)18.2507
2000's12 (17.39)29.6817
2010's31 (44.93)24.3611
2020's13 (18.84)2.80

Authors

AuthorsStudies
Majzoobi, MM1
Hashmi, SH1
Emami, K1
Soltanian, AR1
Yavropoulou, MP1
Filippa, MG1
Panopoulos, S1
Spanos, E1
Spanos, G1
Tektonidou, MG1
Sfikakis, PP1
Basheer, A1
Khan, EA1
Hashmi, T1
Khan, RA1
Ahmad, A1
Zen, M1
Saccon, F1
Gatto, M1
Montesso, G1
Larosa, M1
Benvenuti, F1
Iaccarino, L1
Doria, A2
Zeh, HJ1
Bahary, N1
Boone, BA1
Singhi, AD1
Miller-Ocuin, JL1
Normolle, DP1
Zureikat, AH1
Hogg, ME1
Bartlett, DL1
Lee, KK1
Tsung, A1
Marsh, JW1
Murthy, P1
Tang, D1
Seiser, N1
Amaravadi, RK2
Espina, V1
Liotta, L1
Lotze, MT1
Lazaros, G1
Antonopoulos, AS1
Antonatou, K1
Skendros, P1
Ritis, K1
Hadziyannis, E1
Lazarou, E1
Leontsinis, I1
Simantiris, S1
Vlachopoulos, C1
Tousoulis, D1
Vassilopoulos, D1
Cai, S1
Sun, W1
Li, M1
Dong, L1
Györfi, AH1
Kopp, M1
May, M1
Vetter, M1
Uder, M1
Kremer, AE1
Schett, G1
Harrer, T1
Distler, JHW1
He, F1
Luo, Q1
Lei, M1
Fan, L1
Shao, X1
Hu, K1
Qin, S1
Yu, N1
Cao, J1
Yang, L1
Riva, E1
Sainaghi, PP1
Turriziani, O1
Antonelli, G1
Patti, G1
Nasiri, S1
Dadkhahfar, S1
Abasifar, H1
Mortazavi, N1
Gheisari, M1
Mamishi, S1
Navaeian, A1
Shabanian, R1
Fanouriakis, A1
Tziolos, N1
Bertsias, G1
Boumpas, DT1
Mathian, A1
Pha, M1
Amoura, Z1
Scott, EC2
Maziarz, RT1
Spurgeon, SE1
Medvedova, E1
Gajewski, J1
Reasor-Heard, S1
Park, B1
Kratz, A1
Thomas, GV1
Loriaux, M1
Cascio, M1
Podolak, J1
Gordon, M1
Botelho, J1
Stadtmauer, E1
Amaravadi, R1
Vogl, DT2
Rutledge, GG1
Marr, I1
Huang, GKL1
Auburn, S1
Marfurt, J1
Sanders, M1
White, NJ1
Berriman, M1
Newbold, CI1
Anstey, NM1
Otto, TD1
Price, RN1
Gan, SP1
Ong, SG1
Honda, F1
Tsuboi, H1
Toko, H1
Ohyama, A1
Takahashi, H1
Abe, S1
Yokosawa, M1
Asashima, H1
Hagiwara, S1
Hirota, T1
Kondo, Y1
Matsumoto, I1
Sumida, T1
Lin, YC1
Huang, HH1
Nong, BR1
Liu, PY1
Chen, YY1
Huang, YF1
Chiou, YH1
Lee, HS1
van Roeden, SE1
Bleeker-Rovers, CP1
Kampschreur, LM1
de Regt, MJA1
Vermeulen Windsant, A1
Hoepelman, AIM1
Wever, PC1
Oosterheert, JJ1
Sun, Y1
Ma, L1
Chen, H1
Kong, X1
Lv, P1
Dai, X1
Ji, Z1
Yang, C1
Dai, S1
Wu, L1
Zou, Y1
Lin, J1
Shi, H1
Yu, Q1
Jiang, L1
Vera-Ramirez, L1
Vodnala, SK1
Nini, R1
Hunter, KW1
Green, JE1
Ghasemnejad-Berenji, H1
Ghaffari Novin, M1
Hajshafiha, M1
Nazarian, H1
Hashemi, SM1
Ilkhanizadeh, B1
Ghasemnejad, T1
Sadeghpour, S1
Ghasemnejad-Berenji, M1
Néel, A1
Hello, M1
Cottereau, A1
Graveleau, J1
De Faucal, P1
Costedoat-Chalumeau, N2
Rondeau-Lutz, M1
Lavigne, C1
Chiche, L1
Hachulla, E3
Seiberras, S1
Cabane, J1
Tournemaine, N1
Hamidou, M1
Gunn, TM1
Raz, GM1
Turek, JW1
Farivar, RS1
Yates, M1
Loke, YK1
Watts, RA1
MacGregor, AJ1
Khayat, R1
Dupuy, A1
Pansé, I1
Bagot, M1
Cordoliani, F1
Park, IC1
Baek, YH1
Han, SY1
Lee, SW2
Chung, WT1
Kang, SH1
Cho, DS1
Zhang, LN1
Shi, TY1
Yang, YJ1
Zhang, FC1
Stadtmauer, EA1
Tan, KS1
Heitjan, DF1
Davis, LE1
Pontiggia, L1
Rangwala, R1
Piao, S1
Chang, YC1
Paul, TM1
Nichols, CW1
Porter, DL1
Kaplan, J1
Mallon, G1
Bradner, JE1
Lochouarn, M1
Lagier, JC2
Raoult, D2
Pulcini, C1
Mekinian, A1
Masseau, A1
Botta, A1
Chudzinski, A1
Theulin, A1
Emmanuelli, V1
De Carolis, S1
Revaux, A1
Nicaise, P1
Cornelis, F1
Subtil, D1
Montestruc, F1
Bucourt, M1
Chollet-Martin, S1
Carbillon, L1
Fain, O1
Vincent, D1
Ponard, D1
Fiorella, S1
Drouet, C1
Emonet, S1
Wuillemin, T1
Harbarth, S1
Wassilew, N1
Cikirikcioglu, M1
Schrenzel, J1
van Delden, C1
Julkunen, H2
Prior-Español, Á1
Martínez-Morillo, M1
Riveros-Frutos, A1
Olivé, A1
Hashemie, H1
Klossowski, N1
Oommen, PT1
Neubert, J1
Homey, B1
Hoff, NP1
Reifenberger, J1
Meller, S1
Hartman, O1
Kovanen, PT1
Lehtonen, J1
Eklund, KK1
Sinisalo, J1
ALVING, AS1
Pisoni, CN1
Brucato, A1
Ruffatti, A1
Espinosa, G1
Cervera, R1
Belmonte-Serrano, M1
Sánchez-Román, J1
García-Hernández, FG1
Tincani, A1
Bertero, MT1
Hughes, GR1
Khamashta, MA1
Chen, YA1
Hsu, CK1
Lee, JY1
Yang, CC1
Maschi, C1
Tieulié, N1
Gastaud, P1
Baillif, S1
Hong, YJ1
Yang, SY1
Lee, K1
Kim, TS1
Kim, HB1
Park, KU1
Song, J1
Kim, EC1
Galeone, M1
Arunachalam, M1
Scarfì, F1
Palleschi, GM1
Massi, D1
Difonzo, EM1
Singhal, S1
Zahid, M1
Verstappen, SM1
van Albada-Kuipers, GA1
Bijlsma, JW1
Blaauw, AA1
Schenk, Y1
Haanen, HC1
Jacobs, JW1
Lowry, TR1
Rousso, E1
Noel, E1
Brogard, JM1
Blicklé, JF1
Andrès, E1
Aries, PM1
Reinhold-Keller, E1
Fayad, F1
Lioté, F1
Berenbaum, F1
Orcel, P1
Bardin, T1
Batioğlu, F1
Taner, P1
Aydintuğ, OT1
Heper, AO1
Ozmert, E1
Callejas-Rubio, JL1
Rios-Fernández, R1
Tomás-Jiménez, C1
Ortego-Centeno, N1
Modi, S1
Rosen, T1
Runge, LA1
Krajnc, I1
Louis, E1
Belaïche, J1
Lewis, JE1
Beutner, EH2
Rostami, R1
Chorzelski, TP2
Sibilia, J1
Cribier, B1
Javier, RM1
Pflumio, F1
Kuntz, JL1
Yi, KJ1
Chung, MH1
Kim, HS1
Kim, CS1
Pai, SH1
Shteyngarts, AR1
Warner, MR1
Camisa, C2
Al-Mayouf, SM1
Ghonaium, A1
Bahabri, S1
Arnal, C1
Piette, JC1
Léone, J1
Taillan, B1
Roudot-Thoraval, F1
Papo, T1
Schaeffer, A1
Bierling, P1
Godeau, B1
Thouret, MC1
Sirvent, N1
Triolo, V1
Monteilh, C1
Michiels, J1
Boutté, P1
Petersen, CS1
Thomsen, K1
Parodi, A1
Schosser, R1
Guin, J1
Cardo, PP1
Maciejowska, E1
Valeski, JE1
Kumar, V1
Allen, CM1
Hamzeh, S1
Stephens, L1
Spann, CR1
Callen, JP1
Klein, JB1
Kulick, KB1
Snyder, GG1
McCarthy, RE1
Toomey, JM1
Rothfield, NF1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
An Impaired Functional Reserve of Adrenal Cortex May Associate With difficult-to Treat RA: Can a Disturbed Cortisol Circadian Rhythm Serve as a Predictor of Difficult-to-treat RA?[NCT05671627]50 participants (Anticipated)Observational2022-02-02Recruiting
Optimization of Glucocorticoid Taper Strategies for Maintenance Therapy of Systemic Lupus Erythematosus Associated Immune Thrombocytopenia (SLE-ITP)[NCT05506033]120 participants (Anticipated)Interventional2022-08-15Enrolling by invitation
Safety and Efficacy of Post-exposure Prophylaxis With Hydroxychloroquine (HCQ) for the Prevention of COVID-19 in High-risk Older Individuals in Long-term and Specialized Care: A Double-blind Randomized Control Trial[NCT04397328]Phase 3336 participants (Anticipated)Interventional2020-05-19Not yet recruiting
A Phase I/II Trial of Hydroxychloroquine Added to Bortezomib for Relapsed/Refractory Myeloma[NCT00568880]Phase 125 participants (Actual)Interventional2010-09-08Completed
PATCH 2 & 3: (Prevention and Treatment of COVID-19 With Hydroxychloroquine) A Double-blind Placebo Controlled Randomized Trial of Hydroxychloroquine in the Prevention and Treatment of COVID-19[NCT04353037]Phase 239 participants (Actual)Interventional2020-04-07Terminated (stopped due to As enrollment began external studies called into question the safety and efficacy of hydroxychloroquine as a treatment which resulted in controversy. The timing of the controversy significantly impacted our ability to enroll and retain participants.)
Hydroxychloroquine for the Prevention of Recurrent Cardiovascular Events in Myocardial Infarction Patients - a Safety Pilot Trial[NCT02648464]Phase 4125 participants (Actual)Interventional2016-02-01Completed
Cyclophosphamide and Hydroxychloroquine for the Treatment of Severe Thrombocytopenia in Systemic Lupus Erythematosus[NCT02444728]Phase 350 participants (Actual)Interventional2015-07-31Terminated (stopped due to Because of insufficient enrollement)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Sub Study 1 - Rate of Negative Tests at End of Treatment for COVID-19 Positive PCR Patients in Self-quarantine

Rate of negative tests at end of treatment for COVID-19 positive PCR patients in self-quarantine (NCT04353037)
Timeframe: 1-3 days after completion of 14 day treatment

InterventionParticipants (Count of Participants)
Sub Study 1 Group 1 (HCQ)4
Sub Study 1 Group 2 (Placebo)0

Sub Study 1 - Rate of Negative Tests at End of Treatment for COVID-19 Positive PCR Patients in Self-quarantine

Rate of negative tests at end of treatment for COVID-19 positive PCR patients in self-quarantine (NCT04353037)
Timeframe: 15-17 days after completion of 14 day treatment

InterventionParticipants (Count of Participants)
Sub Study 1 Group 1 (HCQ)6
Sub Study 1 Group 2 (Placebo)0

Sub Study 1 - Secondary Infection of Co-inhabitants of COVID-19 Positive PCR Patients in Self-quarantine

Co-inhabitants of COVID-19 positive PCR patients in self-quarantine that test positive up to 31 days after patient begins treatment with HCQ or Placebo (NCT04353037)
Timeframe: Until completion of study, 29 to 31 days after beginning treatment.

InterventionParticipants (Count of Participants)
Sub Study 1 Group 1 (HCQ)0
Sub Study 1 Group 2 (Placebo)0

Sub Study 2:Health Care Workers:Rate of Hospitalization

if the participant gets COVID and has severe symptoms and hospitalized, end point reached if before the end of the 2 month period (NCT04353037)
Timeframe: Until completion of study, 2 months after start of treatment.

InterventionParticipants (Count of Participants)
Sub Study 2 Group 1 (HCQ)0
Sub Study 2 Group 2 (Placebo)0

Sub Study 2:Number of Health Care Workers Testing Positive at 2 Months

Rate of COVID-19 infection (confirmed by accepted testing methods) at 2 months (NCT04353037)
Timeframe: Until completion of study, 2 months after start of treatment.

InterventionParticipants (Count of Participants)
Sub Study 2 Group 1 (HCQ)0
Sub Study 2 Group 2 (Placebo)0

Substudy 1 - Number of COVID-19+ PCR Patients in Self-quarantine Who Are Hospitalized

Number of COVID-19+ PCR patients in self-quarantine who are hospitalized up to 31 days after beginning HCQ or Placebo (NCT04353037)
Timeframe: Until completion of study, 29 to 31 days after beginning treatment.

InterventionParticipants (Count of Participants)
Sub Study 1 Group 1 (HCQ)0
Sub Study 1 Group 2 (Placebo)0

Sub Study 2:Health Care Workers: Assessment of Any Medical Events That Occur During the ~60 Day Active Period

Assessment of any medical events that occur during the ~60 day active period that is felt to be related to receipt of HCQ (NCT04353037)
Timeframe: Until completion of study, 2 months (~60 days) after start of treatment.

,
InterventionParticipants (Count of Participants)
moderate adverse eventsminor adverse events
Sub Study 2 Group 1 (HCQ)21
Sub Study 2 Group 2 (Placebo)00

Reviews

10 reviews available for hydroxychloroquine and Recrudescence

ArticleYear
A complex COVID-19 case with rheumatoid arthritis treated with tocilizumab.
    Clinical rheumatology, 2020, Volume: 39, Issue:9

    Topics: Aged; Anti-Bacterial Agents; Antifungal Agents; Antirheumatic Agents; Antiviral Agents; Arthritis, R

2020
Successful recovery of recurrence of positive SARS-CoV-2 RNA in COVID-19 patient with systemic lupus erythematosus: a case report and review.
    Clinical rheumatology, 2020, Volume: 39, Issue:9

    Topics: Adult; Anti-Bacterial Agents; Antirheumatic Agents; Antiviral Agents; Betacoronavirus; Clinical Labo

2020
Update οn the diagnosis and management of systemic lupus erythematosus.
    Annals of the rheumatic diseases, 2021, Volume: 80, Issue:1

    Topics: Anemia, Hemolytic, Autoimmune; Antibodies, Monoclonal, Humanized; Autoantibodies; Azathioprine; Calc

2021
Cardiac manifestations of Q fever infection: case series and a review of the literature.
    Journal of cardiac surgery, 2013, Volume: 28, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Antirheumatic Agents; Aortic Coarctation; Aortic Valve Insufficiency;

2013
Prednisolone combined with adjunctive immunosuppression is not superior to prednisolone alone in terms of efficacy and safety in giant cell arteritis: meta-analysis.
    Clinical rheumatology, 2014, Volume: 33, Issue:2

    Topics: Adalimumab; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Dap

2014
[Palindromic rheumatism or incipient rheumatoid arthritis--chances of drug therapy].
    Duodecim; laaketieteellinen aikakauskirja, 2014, Volume: 130, Issue:19

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Disease Progression; Humans; Hydroxychloroquine; Medica

2014
Linear lupus panniculitis of the scalp presenting as alopecia along Blaschko's lines: a distinct variant of lupus panniculitis in East Asians?
    The Journal of dermatology, 2012, Volume: 39, Issue:4

    Topics: Adult; Alopecia; Asian People; Humans; Hydroxychloroquine; Male; Panniculitis, Lupus Erythematosus;

2012
Chronic ulcerative stomatitis with stratified epithelium-specific antinuclear antibodies.
    International journal of dermatology, 1996, Volume: 35, Issue:4

    Topics: Aged; Antibodies, Antinuclear; Antirheumatic Agents; Binding Sites, Antibody; Biomarkers; Biopsy; Ce

1996
Lupus erythematosus associated with erythema multiforme: does Rowell's syndrome exist?
    Journal of the American Academy of Dermatology, 1999, Volume: 40, Issue:5 Pt 1

    Topics: Adult; Azathioprine; Cathartics; Dermatologic Agents; Diagnosis, Differential; Erythema Multiforme;

1999
Cheilitis granulomatosa: report of six cases and review of the literature.
    Journal of the American Academy of Dermatology, 1990, Volume: 23, Issue:3 Pt 1

    Topics: Adult; Female; Humans; Hydroxychloroquine; Male; Melkersson-Rosenthal Syndrome; Middle Aged; Recurre

1990

Trials

6 trials available for hydroxychloroquine and Recrudescence

ArticleYear
Combination of doxycycline, streptomycin and hydroxychloroquine for short-course treatment of brucellosis: a single-blind randomized clinical trial.
    Infection, 2022, Volume: 50, Issue:5

    Topics: Anti-Bacterial Agents; Brucellosis; Doxycycline; Drug Therapy, Combination; Humans; Hydroxychloroqui

2022
A Randomized Phase II Preoperative Study of Autophagy Inhibition with High-Dose Hydroxychloroquine and Gemcitabine/Nab-Paclitaxel in Pancreatic Cancer Patients.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2020, 07-01, Volume: 26, Issue:13

    Topics: Adult; Aged; Aged, 80 and over; Albumins; Antineoplastic Combined Chemotherapy Protocols; Autophagy;

2020
Combined autophagy and proteasome inhibition: a phase 1 trial of hydroxychloroquine and bortezomib in patients with relapsed/refractory myeloma.
    Autophagy, 2014, Volume: 10, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Boronic Acids; Bortezomib; D

2014
Combined autophagy and proteasome inhibition: a phase 1 trial of hydroxychloroquine and bortezomib in patients with relapsed/refractory myeloma.
    Autophagy, 2014, Volume: 10, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Boronic Acids; Bortezomib; D

2014
Combined autophagy and proteasome inhibition: a phase 1 trial of hydroxychloroquine and bortezomib in patients with relapsed/refractory myeloma.
    Autophagy, 2014, Volume: 10, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Boronic Acids; Bortezomib; D

2014
Combined autophagy and proteasome inhibition: a phase 1 trial of hydroxychloroquine and bortezomib in patients with relapsed/refractory myeloma.
    Autophagy, 2014, Volume: 10, Issue:8

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Boronic Acids; Bortezomib; D

2014
Hydroxychloroquine for the prevention of recurrent cardiovascular events in myocardial infarction patients: rationale and design of the OXI trial.
    European heart journal. Cardiovascular pharmacotherapy, 2017, 04-01, Volume: 3, Issue:2

    Topics: Antirheumatic Agents; Atherosclerosis; Double-Blind Method; Humans; Hydroxychloroquine; Myocardial I

2017
A good response to early DMARD treatment of patients with rheumatoid arthritis in the first year predicts remission during follow up.
    Annals of the rheumatic diseases, 2005, Volume: 64, Issue:1

    Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Follow-Up Studies; Humans; Hydroxy

2005
Treatment of severe immune thrombocytopenia associated with systemic lupus erythematosus: 59 cases.
    The Journal of rheumatology, 2002, Volume: 29, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cohort Studies; Danazol; Drug Administration Routes; Dru

2002

Other Studies

53 other studies available for hydroxychloroquine and Recrudescence

ArticleYear
Impaired adrenal cortex reserve in patients with rheumatic and musculoskeletal diseases who relapse upon tapering of low glucocorticoid dose.
    Clinical and experimental rheumatology, 2022, Volume: 40, Issue:9

    Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Insufficiency; Antirheumatic Agents; Arthritis, Rhe

2022
Recurrent aseptic meningitis: A rare clinical presentation of Sjogren's syndrome.
    JPMA. The Journal of the Pakistan Medical Association, 2019, Volume: 69, Issue:10

    Topics: Antibodies, Antinuclear; Antirheumatic Agents; Fatigue; Female; Glucocorticoids; Humans; Hydroxychlo

2019
Prevalence and predictors of flare after immunosuppressant discontinuation in patients with systemic lupus erythematosus in remission.
    Rheumatology (Oxford, England), 2020, 07-01, Volume: 59, Issue:7

    Topics: Adult; Antimalarials; Antirheumatic Agents; Azathioprine; Cyclosporine; Deprescriptions; Female; Hum

2020
Hydroxychloroquine for colchicine-resistant glucocorticoid-dependent idiopathic recurrent pericarditis: A pilot observational prospective study.
    International journal of cardiology, 2020, 07-15, Volume: 311

    Topics: Colchicine; Glucocorticoids; Humans; Hydroxychloroquine; Pericarditis; Prospective Studies; Recurren

2020
Glucocorticoid-induced relapse of COVID-19 in a patient with sarcoidosis.
    Annals of the rheumatic diseases, 2021, Volume: 80, Issue:6

    Topics: Chronic Disease; COVID-19; Glucocorticoids; Humans; Hydroxychloroquine; Recurrence; Sarcoidosis

2021
SARS-CoV-2 infection: diagnostic testing results occasionally require special attention.
    Emerging microbes & infections, 2020, Volume: 9, Issue:1

    Topics: Antibodies, Viral; Betacoronavirus; Coronavirus Infections; COVID-19; Enzyme-Linked Immunosorbent As

2020
Urticarial vasculitis in a COVID-19 recovered patient.
    International journal of dermatology, 2020, Volume: 59, Issue:10

    Topics: Azithromycin; COVID-19; COVID-19 Drug Treatment; Drug Therapy, Combination; Female; Histamine Antago

2020
Acute aortic dissection in a patient with Williams syndrome infected by COVID-19.
    Cardiology in the young, 2021, Volume: 31, Issue:1

    Topics: Adolescent; Anti-Bacterial Agents; Antiviral Agents; Aortic Aneurysm; Aortic Dissection; Aortic Sten

2021
[Therapeutic de-escalation in systemic lupus erythematosus in remission].
    La Revue de medecine interne, 2020, Volume: 41, Issue:12

    Topics: Dose-Response Relationship, Drug; Humans; Hydroxychloroquine; Lupus Erythematosus, Systemic; Mainten

2020
Double autophagy stimulation using chemotherapy and mTOR inhibition combined with hydroxychloroquine for autophagy modulation in patients with relapsed or refractory multiple myeloma.
    Haematologica, 2017, Volume: 102, Issue:7

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Autophagy; Bone Marrow; Cel

2017
Genomic Characterization of Recrudescent Plasmodium malariae after Treatment with Artemether/Lumefantrine.
    Emerging infectious diseases, 2017, Volume: 23, Issue:8

    Topics: Adult; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Combinations; Dr

2017
Antithrombotic effects of hydroxychloroquine in a pregnant patient with Antiphospholipid syndrome and recurrent venous thromboembolism.
    The Medical journal of Malaysia, 2017, Volume: 72, Issue:2

    Topics: Antiphospholipid Syndrome; Antithrombins; Female; Humans; Hydroxychloroquine; Pregnancy; Pregnancy C

2017
Recurrent Kikuchi-Fujimoto Disease Successfully Treated by the Concomitant Use of Hydroxychloroquine and Corticosteroids.
    Internal medicine (Tokyo, Japan), 2017, Dec-15, Volume: 56, Issue:24

    Topics: Adult; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Histiocytic Necrotizing

2017
Pediatric Kikuchi-Fujimoto disease: A clinicopathologic study and the therapeutic effects of hydroxychloroquine.
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2019, Volume: 52, Issue:3

    Topics: Adolescent; Adrenal Cortex Hormones; Biopsy; Child; Diagnosis, Differential; Female; Histiocytic Nec

2019
The effect of measuring serum doxycycline concentrations on clinical outcomes during treatment of chronic Q fever.
    The Journal of antimicrobial chemotherapy, 2018, 04-01, Volume: 73, Issue:4

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Doxycycline; Drug Monitoring; Female; Humans; Hydrox

2018
Analysis of predictive factors for treatment resistance and disease relapse in Takayasu's arteritis.
    Clinical rheumatology, 2018, Volume: 37, Issue:10

    Topics: Adult; Age Factors; Benzimidazoles; Blood Sedimentation; C-Reactive Protein; China; Cyclophosphamide

2018
Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence.
    Nature communications, 2018, 05-22, Volume: 9, Issue:1

    Topics: Adenine; Animals; Autophagy; Autophagy-Related Protein 7; Beclin-1; Breast Neoplasms; Caspases; Cell

2018
Immunomodulatory effects of hydroxychloroquine on Th1/Th2 balance in women with repeated implantation failure.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 107

    Topics: Adult; Embryo Implantation; Female; Fertilization in Vitro; Humans; Hydroxychloroquine; Immunomodula

2018
Long-term outcome in idiopathic granulomatous mastitis: a western multicentre study.
    QJM : monthly journal of the Association of Physicians, 2013, Volume: 106, Issue:5

    Topics: Adult; Colchicine; Drug Utilization; Female; Glucocorticoids; Granulomatous Mastitis; Humans; Hydrox

2013
[Sclerodermatous changes in porphyria cutanea tarda: six cases].
    Annales de dermatologie et de venereologie, 2013, Volume: 140, Issue:10

    Topics: Adrenal Cortex Hormones; Aged; Alcoholism; Alopecia; Diagnosis, Differential; Female; Humans; Hydrox

2013
Simultaneous intrahepatic and subgaleal hemorrhage in antiphospholipid syndrome following anticoagulation therapy.
    World journal of gastroenterology, 2013, Oct-14, Volume: 19, Issue:38

    Topics: Adolescent; Anticoagulants; Antiphospholipid Syndrome; Chemical and Drug Induced Liver Injury; Clopi

2013
An SLE patient with prolactinoma and recurrent granulomatous mastitis successfully treated with hydroxychloroquine and bromocriptine.
    Lupus, 2014, Volume: 23, Issue:4

    Topics: Bromocriptine; Female; Granulomatous Mastitis; Hormone Antagonists; Humans; Hydroxychloroquine; Lupu

2014
A case of Whipple's disease evolving over 30 years.
    Medecine et maladies infectieuses, 2014, Volume: 44, Issue:7

    Topics: Anti-Bacterial Agents; Antibodies, Bacterial; Aortic Valve Insufficiency; Biopsy; Disease Progressio

2014
Chronic histiocytic intervillositis: outcome, associated diseases and treatment in a multicenter prospective study.
    Autoimmunity, 2015, Volume: 48, Issue:1

    Topics: Abortion, Habitual; Adult; Aspirin; Autoantibodies; Autoimmune Diseases; Cell Movement; Chorionic Vi

2015
Benefits of hydroxychloroquine in the treatment of a patient with angioedema due to acquired C1 inhibitor deficiency.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2015, Volume: 114, Issue:1

    Topics: Aged; Angioedema; Angioedemas, Hereditary; Antibodies, Blocking; Autoantibodies; Autoimmunity; Compl

2015
Relapse of Tropheryma whipplei endocarditis treated by trimethoprim/sulfamethoxazole, cured by hydroxychloroquine plus doxycycline.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2015, Volume: 30

    Topics: Anti-Bacterial Agents; Aortic Valve; Ceftriaxone; Doxycycline; Drug Therapy, Combination; Endocardit

2015
[Recurrent diffuse alveolar hemorrhage in systemic lupus erytematosus treated with rituximab and immunoglobulins].
    Medicina clinica, 2015, Dec-07, Volume: 145, Issue:11

    Topics: Cyclophosphamide; Drug Therapy, Combination; Hemorrhage; Humans; Hydroxychloroquine; Immunoglobulins

2015
[Juvenile systemic lupus erythematosus with unusual manifestation of lupus-associated panniculitis].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2015, Volume: 66, Issue:10

    Topics: Adolescent; Anti-Inflammatory Agents; Diagnosis, Differential; Drug Therapy, Combination; Humans; Hy

2015
Successful Treatment of Intermittent Hydrarthrosis With Hydroxychloroquine.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2015, Volume: 21, Issue:8

    Topics: Antirheumatic Agents; Diagnosis, Differential; Female; Humans; Hydrarthrosis; Hydroxychloroquine; Kn

2015
Study of pentaquine and isopentaquine, therapeutic agents effective in reducing relapse rate in vivax malaria.
    Abstracts. International Congress on Tropical Medicine and Malaria (4th : 1948 : Washington, D. C.), 1948, Volume: 56, Issue:4th Congr

    Topics: Aminoquinolines; Hydroxychloroquine; Hydroxyquinolines; Malaria; Malaria, Vivax; Recurrence

1948
Failure of intravenous immunoglobulin to prevent congenital heart block: Findings of a multicenter, prospective, observational study.
    Arthritis and rheumatism, 2010, Volume: 62, Issue:4

    Topics: Autoantigens; Dexamethasone; Drug Therapy, Combination; Female; Heart Block; Heart Defects, Congenit

2010
Use of hydroxychloroquine in corticodependent and recurrent scleritis.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2013, Volume: 251, Issue:3

    Topics: Adult; Antirheumatic Agents; Drug Therapy, Combination; Glucocorticoids; Humans; Hydroxychloroquine;

2013
A case of imported Plasmodium malariae malaria.
    Annals of laboratory medicine, 2012, Volume: 32, Issue:3

    Topics: Antimalarials; Drug Resistance; Female; Humans; Hydroxychloroquine; Malaria; Mefloquine; Plasmodium

2012
Unilateral eyelid involvement in discoid lupus erythematosus.
    International journal of dermatology, 2014, Volume: 53, Issue:7

    Topics: Adult; Antirheumatic Agents; Blepharitis; Chalazion; Female; Humans; Hydroxychloroquine; Lupus Eryth

2014
Palindromic rheumatism.
    Journal of the Indian Medical Association, 2002, Volume: 100, Issue:3

    Topics: Adult; Drug Administration Schedule; Finger Joint; Humans; Hydroxychloroquine; India; Male; Pain Mea

2002
Sarcoidosis of nasal ala and lower lip.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2004, Volume: 131, Issue:1

    Topics: Adult; Biopsy; Dermatologic Agents; Humans; Hydroxychloroquine; Male; Mouth Diseases; Nose Diseases;

2004
[Recurrent facial palsy, primary Gougerot-Sjögren's syndrome and vitamin B12 deficiency].
    Presse medicale (Paris, France : 1983), 2005, Jan-29, Volume: 34, Issue:2 Pt 1

    Topics: Adult; Anti-Inflammatory Agents; Antirheumatic Agents; Electromyography; Facial Paralysis; Female; H

2005
[Symmetric polyarthritis in a patient with Churg-Strauss syndrome].
    Deutsche medizinische Wochenschrift (1946), 2005, Aug-19, Volume: 130, Issue:33

    Topics: Antibodies, Monoclonal; Antirheumatic Agents; Arthritis; Azathioprine; Churg-Strauss Syndrome; Cyclo

2005
Muscle involvement in sarcoidosis: a retrospective and followup studies.
    The Journal of rheumatology, 2006, Volume: 33, Issue:1

    Topics: Adult; Cardiomyopathies; Chronic Disease; Dose-Response Relationship, Drug; Female; Follow-Up Studie

2006
Recurrent optic disc and retinal vasculitis in a patient with drug-induced urticarial vasculitis.
    Cutaneous and ocular toxicology, 2006, Volume: 25, Issue:4

    Topics: Anti-Infective Agents; Dermatologic Agents; Drug Industry; Drug Therapy, Combination; Female; Glucoc

2006
Corticosteroids in preventing severe lupus flares: do all patients have the same risk? Comment on the article by Tseng et al.
    Arthritis and rheumatism, 2007, Volume: 56, Issue:6

    Topics: Adrenal Cortex Hormones; Antibodies, Anti-Idiotypic; Antirheumatic Agents; DNA; Dose-Response Relati

2007
Micropapular cutaneous sarcoidosis: case series successfully managed with hydroxychloroquine sulfate.
    Cutis, 2008, Volume: 81, Issue:4

    Topics: Adult; Antirheumatic Agents; Diagnosis, Differential; Female; Humans; Hydroxychloroquine; Male; Recu

2008
Risk/benefit analysis of hydroxychloroquine sulfate treatment in rheumatoid arthritis.
    The American journal of medicine, 1983, Jul-18, Volume: 75, Issue:1A

    Topics: Actuarial Analysis; Arthritis, Rheumatoid; Gastrointestinal Diseases; Gold; Humans; Hydroxychloroqui

1983
[Palindromic rheumatism--progression to erosive rheumatoid arthritis--presentation of 3 years treatment of a patient].
    Acta medica Austriaca, 1995, Volume: 22, Issue:1-2

    Topics: Adult; Arthritis, Rheumatoid; Arthrography; Diagnosis, Differential; Follow-Up Studies; Humans; Hydr

1995
Hydroxychloroquine (Plaquenil) for recurrence prevention of Crohn's disease after curative surgery.
    Gastroenterologie clinique et biologique, 1995, Volume: 19, Issue:2

    Topics: Crohn Disease; Humans; Hydroxychloroquine; Postoperative Care; Recurrence

1995
Recurrent psoriatic onychoperiostitis induced by hydroxychloroquine.
    Revue du rhumatisme (English ed.), 1995, Volume: 62, Issue:11

    Topics: Female; Humans; Hydroxychloroquine; Middle Aged; Nail Diseases; Periostitis; Psoriasis; Recurrence;

1995
A relapsed case of imported tertian malaria after a standard course of hydroxychloroquine and primaquine therapy.
    The Korean journal of parasitology, 1998, Volume: 36, Issue:2

    Topics: Adult; Animals; Antimalarials; Humans; Hydroxychloroquine; Malaria, Vivax; Male; Primaquine; Recurre

1998
Hypergammaglobulinaemic purpura associated with IgG subclass imbalance and recurrent infection.
    Clinical rheumatology, 2000, Volume: 19, Issue:6

    Topics: Child, Preschool; Disease Progression; Humans; Hydroxychloroquine; Immunoglobulin G; Infections; Mal

2000
[Primary Gougerot-Sjögren syndrome in a 13-year-old girl].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2002, Volume: 9, Issue:2

    Topics: Adolescent; Antirheumatic Agents; Biopsy; Female; Humans; Hydroxychloroquine; Parotitis; Recurrence;

2002
High-dose hydroxychloroquine treatment of porphyria cutanea tarda.
    Journal of the American Academy of Dermatology, 1992, Volume: 26, Issue:4

    Topics: Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Female; Follow-Up Studies; Humans; Hyd

1992
Ten cases of chronic ulcerative stomatitis with stratified epithelium-specific antinuclear antibody.
    Journal of the American Academy of Dermatology, 1991, Volume: 24, Issue:5 Pt 1

    Topics: Adult; Aged; Antibodies, Antinuclear; Chronic Disease; Female; Fluorescent Antibody Technique; Gingi

1991
Clinical, serologic and immunogenetic studies in patients with chronic cutaneous (discoid) lupus erythematosus who have verrucous and/or hypertrophic skin lesions.
    The Journal of rheumatology, 1988, Volume: 15, Issue:2

    Topics: Adrenal Cortex Hormones; Adult; Antibodies, Antinuclear; Chronic Disease; DNA, Single-Stranded; Fema

1988
Nasal septal perforation in systemic lupus erythematosus.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1974, Volume: 99, Issue:6

    Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Epistaxis; Female; Fluorescent Ant

1974