hydroxychloroquine has been researched along with Pulmonary Embolism in 14 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Pulmonary Embolism: Blocking of the PULMONARY ARTERY or one of its branches by an EMBOLUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a double-blind, randomized trial of orally administered hydroxychloroquine sulphate in the prevention of venous thromboembolism after elective surgery on the hip, the drug or a placebo was given to fifty consecutive patients." | 9.04 | Failure of orally administered hydroxychloroquine sulphate to prevent venous thromboembolism following elective hip operations. ( Ainsworth, ME; Bowcock, SA; Cooke, ED; Dawson, MH; Ibbotson, RM; Pilcher, MF, 1977) |
| "Evidence for the usefulness of hydroxychloroquine as prophylaxis against thromboembolism after total hip replacement is examined." | 8.77 | Hydroxychloroquine and postoperative thromboembolism after total hip replacement. ( Loudon, JR, 1988) |
| "Hydroxychloroquine (HCQ) has a primary role in the prophylaxis and treatment of systemic lupus erythematosus (SLE) and may be protective against thrombosis in SLE." | 8.02 | Association of Higher Hydroxychloroquine Blood Levels With Reduced Thrombosis Risk in Systemic Lupus Erythematosus. ( Goldman, DW; Konig, MF; Li, J; Petri, M, 2021) |
| "In a double-blind, randomized trial of orally administered hydroxychloroquine sulphate in the prevention of venous thromboembolism after elective surgery on the hip, the drug or a placebo was given to fifty consecutive patients." | 5.04 | Failure of orally administered hydroxychloroquine sulphate to prevent venous thromboembolism following elective hip operations. ( Ainsworth, ME; Bowcock, SA; Cooke, ED; Dawson, MH; Ibbotson, RM; Pilcher, MF, 1977) |
| "Evidence for the usefulness of hydroxychloroquine as prophylaxis against thromboembolism after total hip replacement is examined." | 4.77 | Hydroxychloroquine and postoperative thromboembolism after total hip replacement. ( Loudon, JR, 1988) |
| "Hydroxychloroquine (HCQ) has a primary role in the prophylaxis and treatment of systemic lupus erythematosus (SLE) and may be protective against thrombosis in SLE." | 4.02 | Association of Higher Hydroxychloroquine Blood Levels With Reduced Thrombosis Risk in Systemic Lupus Erythematosus. ( Goldman, DW; Konig, MF; Li, J; Petri, M, 2021) |
| "Diffuse alveolar hemorrhage is an uncommon and often fatal condition in children that is characterized by distinct histopathological etiologies." | 1.51 | Acute pulmonary embolism in a child with ANCA-negative Idiopathic Pulmonary Capillaritis. ( Asseri, AA; Daines, CL; Zeng, Y, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (64.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 4 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| He, M | 1 |
| Pawar, A | 1 |
| Desai, RJ | 1 |
| Glynn, RJ | 1 |
| Lee, H | 1 |
| Weinblatt, ME | 1 |
| Solomon, DH | 1 |
| Kim, SC | 1 |
| Zhao, Y | 2 |
| Huang, C | 1 |
| You, H | 1 |
| Zhao, J | 1 |
| Wang, Q | 1 |
| Tian, X | 1 |
| Li, M | 1 |
| Zeng, X | 1 |
| Petri, M | 1 |
| Konig, MF | 1 |
| Li, J | 1 |
| Goldman, DW | 1 |
| Ortiz Molina, E | 1 |
| Hernandez Pailos, R | 1 |
| Pola Guillen, M | 1 |
| Pascual Pedreno, A | 1 |
| Rodriguez Rodriguez, E | 1 |
| Hernandez Martinez, A | 1 |
| Asseri, AA | 1 |
| Zeng, Y | 1 |
| Daines, CL | 1 |
| Verstraete, M | 1 |
| Cooke, ED | 1 |
| Dawson, MH | 1 |
| Ibbotson, RM | 1 |
| Bowcock, SA | 1 |
| Ainsworth, ME | 1 |
| Pilcher, MF | 1 |
| Sasahara, AA | 1 |
| Sharma, GV | 1 |
| Parisi, AF | 1 |
| Uhl, JF | 1 |
| Huguier, M | 1 |
| Johnson, R | 3 |
| Charnley, J | 2 |
| Green, JR | 1 |
| Genton, E | 1 |
| Gent, M | 1 |
| Hirsh, J | 1 |
| Harker, LA | 1 |
| Loudon, JR | 2 |
4 reviews available for hydroxychloroquine and Pulmonary Embolism
| Article | Year |
|---|---|
[Critical evaluation of the usefulness of drugs inhibiting platelet function in the prevention of postoperative deep venous thrombosis and in ischemic cardiopathy].
Topics: Anticoagulants; Aspirin; Clofibrate; Coronary Disease; Dipyridamole; Fibrinolytic Agents; Flurbiprof | 1980 |
New developments in the detection and prevention of venous thromboembolism.
Topics: Aspirin; Clothing; Dextrans; Electric Stimulation Therapy; Fibrinolytic Agents; Heparin; Hip Joint; | 1979 |
[Prevention of thrombosis and embolism in digestive surgery].
Topics: Anticoagulants; Aspirin; Coumarins; Dextrans; Digestive System Surgical Procedures; Dipyridamole; He | 1979 |
Hydroxychloroquine and postoperative thromboembolism after total hip replacement.
Topics: Biomechanical Phenomena; Hip Prosthesis; Humans; Hydroxychloroquine; Pulmonary Embolism; Thromboembo | 1988 |
2 trials available for hydroxychloroquine and Pulmonary Embolism
| Article | Year |
|---|---|
Failure of orally administered hydroxychloroquine sulphate to prevent venous thromboembolism following elective hip operations.
Topics: Administration, Oral; Aged; Arthroplasty; Body Weight; Clinical Trials as Topic; Double-Blind Method | 1977 |
Platelet-inhibiting drugs in the prevention of clinical thrombotic disease (third of three parts).
Topics: Anticoagulants; Aspirin; Clinical Trials as Topic; Clofibrate; Dipyridamole; Drug Evaluation; Fibrin | 1975 |
8 other studies available for hydroxychloroquine and Pulmonary Embolism
| Article | Year |
|---|---|
Risk of venous thromboembolism associated with methotrexate versus hydroxychloroquine for rheumatoid arthritis: A propensity score-matched cohort study.
Topics: Aged; Arthritis, Rheumatoid; Cohort Studies; Female; Humans; Hydroxychloroquine; Incidence; Male; Me | 2021 |
Prognostic factors of systemic lupus erythematosus patients with pulmonary embolism: An 11-year cohort study.
Topics: Adult; Anticoagulants; Cohort Studies; Humans; Hydroxychloroquine; Lupus Erythematosus, Systemic; Ly | 2022 |
Association of Higher Hydroxychloroquine Blood Levels With Reduced Thrombosis Risk in Systemic Lupus Erythematosus.
Topics: Adult; Antirheumatic Agents; Chromatography, Liquid; Female; Fingers; Gangrene; Humans; Hydroxychlor | 2021 |
COVID-19 infection in symptomatic pregnant women at the midpoint of the pandemic in Spain: a retrospective analysis.
Topics: Adult; Anosmia; Anti-Bacterial Agents; Anticoagulants; Antiviral Agents; C-Reactive Protein; Cesarea | 2020 |
Acute pulmonary embolism in a child with ANCA-negative Idiopathic Pulmonary Capillaritis.
Topics: Acute Disease; Antibodies, Antineutrophil Cytoplasmic; Capillaries; Chest Pain; Child; Female; Hemor | 2019 |
Hydroxychloroquine in prophylaxis of pulmonary embolism following hip arthroplasty.
Topics: Dextrans; Drug Therapy, Combination; Hip Joint; Hip Prosthesis; Humans; Hydroxychloroquine; Postoper | 1979 |
Pulmonary embolism and its prophylaxis following the Charnley total hip replacement.
Topics: Blood Transfusion; Early Ambulation; Heparin; Hip; Humans; Hydroxychloroquine; Infusions, Parenteral | 1977 |
Hydroxychloroquine sulfate prophylaxis for pulmonary embolism for patients with low-friction arthroplasty.
Topics: Dextrans; Hip Prosthesis; Humans; Hydroxychloroquine; Postoperative Complications; Pulmonary Embolis | 1986 |