hydroxychloroquine has been researched along with Pulmonary Alveolar Proteinosis in 3 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Pulmonary Alveolar Proteinosis: A PULMONARY ALVEOLI-filling disease, characterized by dense phospholipoproteinaceous deposits in the alveoli, cough, and DYSPNEA. This disease is often related to, congenital or acquired, impaired processing of PULMONARY SURFACTANTS by alveolar macrophages, a process dependent on GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arıkan-Ayyıldız, Z | 1 |
| Caglayan-Sozmen, S | 1 |
| Isık, S | 1 |
| Deterding, R | 1 |
| Dishop, MK | 1 |
| Couderc, R | 1 |
| Epaud, R | 1 |
| Louha, M | 1 |
| Uzuner, N | 1 |
| Hayes, D | 1 |
| Lloyd, EA | 1 |
| Fitch, JA | 1 |
| Bush, A | 1 |
| Rabach, I | 1 |
| Poli, F | 1 |
| Zennaro, F | 1 |
| Germani, C | 1 |
| Ventura, A | 1 |
| Barbi, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Hydroxychloroquine in Pediatric ILD With Genetic Surfactant Dysfunction Disorders: Cross-control, Prospective Study[NCT03822780] | 25 participants (Anticipated) | Interventional | 2017-07-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for hydroxychloroquine and Pulmonary Alveolar Proteinosis
| Article | Year |
|---|---|
Survival of an infant with homozygous surfactant protein C (SFTPC) mutation.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Azithromycin; Consanguinity; Genes, Recessive; Homo | 2014 |
ABCA3 transporter deficiency.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; ATP-Binding Cassette Transporters; Azithromycin; Dr | 2012 |
Is treatment with hydroxychloroquine effective in surfactant protein C deficiency?
Topics: Disease Progression; Diseases in Twins; Dyspnea; Failure to Thrive; Humans; Hydroxychloroquine; Infa | 2013 |