hydroxychloroquine has been researched along with Postoperative Complications in 27 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a double-blind, randomized trial of orally administered hydroxychloroquine sulphate in the prevention of venous thromboembolism after elective surgery on the hip, the drug or a placebo was given to fifty consecutive patients." | 9.04 | Failure of orally administered hydroxychloroquine sulphate to prevent venous thromboembolism following elective hip operations. ( Ainsworth, ME; Bowcock, SA; Cooke, ED; Dawson, MH; Ibbotson, RM; Pilcher, MF, 1977) |
| " Seventy-four patients about to undergo primary unilateral total hip arthroplasty for osteoarthrosis, all receiving a standard thrombosis prophylaxis regime of thigh-length anti-embolic stockings, 5,000 IU heparin delivered subcutaneously twice daily, and 400 mg hydroxychloroquine sulfate delivered twice daily, were entered in a prospective trial." | 5.07 | The effectiveness of intermittent plantar venous compression in prevention of deep venous thrombosis after total hip arthroplasty. ( Bradley, JG; Jager, HJ; Krugener, GH, 1993) |
| "In a double-blind, randomized trial of orally administered hydroxychloroquine sulphate in the prevention of venous thromboembolism after elective surgery on the hip, the drug or a placebo was given to fifty consecutive patients." | 5.04 | Failure of orally administered hydroxychloroquine sulphate to prevent venous thromboembolism following elective hip operations. ( Ainsworth, ME; Bowcock, SA; Cooke, ED; Dawson, MH; Ibbotson, RM; Pilcher, MF, 1977) |
| "A minority of patients who acquire acute Q fever will subsequently develop chronic Q fever endocarditis, which often manifests in valvular insufficiency." | 2.49 | Cardiac manifestations of Q fever infection: case series and a review of the literature. ( Farivar, RS; Gunn, TM; Raz, GM; Turek, JW, 2013) |
| "Mucormycosis is an invasive fungal infection (IFI) due to several species of saprophytic fungi, occurring in patients with underlying co-morbidities (including organ transplantation)." | 1.62 | Mucormycosis after Coronavirus disease 2019 infection in a heart transplant recipient - Case report and review of literature. ( Berlinrut, I; Chang, KM; Khatri, A; Wallach, F, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (74.07) | 18.7374 |
| 1990's | 1 (3.70) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (7.41) | 24.3611 |
| 2020's | 4 (14.81) | 2.80 |
| Authors | Studies |
|---|---|
| Aminian, A | 1 |
| Kermansaravi, M | 1 |
| Azizi, S | 1 |
| Alibeigi, P | 1 |
| Safamanesh, S | 1 |
| Mousavimaleki, A | 1 |
| Rezaei, MT | 1 |
| Faridi, M | 1 |
| Mokhber, S | 1 |
| Pazouki, A | 1 |
| Safari, S | 1 |
| Gegúndez-Fernández, JA | 1 |
| Zarranz-Ventura, J | 1 |
| Garay-Aramburu, G | 1 |
| Muñoz-Negrete, FJ | 1 |
| Mendicute Del Barrio, J | 1 |
| Pablo-Júlvez, L | 1 |
| García-Delpech, S | 1 |
| López-Alemany, A | 1 |
| Arnalich-Montiel, F | 1 |
| Cordero-Coma, M | 1 |
| Cárceles, JA | 1 |
| Inama, G | 1 |
| Dodi, C | 1 |
| Provini, M | 1 |
| Bossoni, E | 1 |
| Inama, L | 1 |
| Balzarini, L | 1 |
| Mancini, C | 1 |
| Ramponi, S | 1 |
| Marvisi, M | 1 |
| Khatri, A | 1 |
| Chang, KM | 1 |
| Berlinrut, I | 1 |
| Wallach, F | 1 |
| Thimm, MA | 1 |
| Rositch, AF | 1 |
| VandenBussche, C | 1 |
| McDonald, L | 1 |
| Garonzik Wang, JM | 1 |
| Levinson, K | 1 |
| Gunn, TM | 1 |
| Raz, GM | 1 |
| Turek, JW | 1 |
| Farivar, RS | 1 |
| YAFFEE, HS | 1 |
| Verstraete, M | 1 |
| Bradley, JG | 1 |
| Krugener, GH | 1 |
| Jager, HJ | 1 |
| Hume, M | 2 |
| Bierbaum, B | 1 |
| Kuriakose, TX | 2 |
| Surprenant, J | 2 |
| Cooke, ED | 1 |
| Dawson, MH | 1 |
| Ibbotson, RM | 1 |
| Bowcock, SA | 1 |
| Ainsworth, ME | 1 |
| Pilcher, MF | 1 |
| Kher, A | 1 |
| Toulemonde, F | 1 |
| Sasahara, AA | 1 |
| Sharma, GV | 1 |
| Parisi, AF | 1 |
| Uhl, JF | 1 |
| Huguier, M | 1 |
| Hirsh, J | 3 |
| Dettori, AG | 1 |
| Pini, M | 1 |
| Quintavalla, R | 1 |
| Johnson, R | 3 |
| Charnley, J | 2 |
| Chrisman, OD | 1 |
| Snook, GA | 1 |
| Wilson, TC | 1 |
| Short, JY | 1 |
| Green, JR | 1 |
| Turner, RH | 1 |
| Joffe, SN | 1 |
| Gent, M | 2 |
| Genton, E | 2 |
| Harker, LA | 1 |
| Pilcher, DB | 1 |
| Loudon, JR | 1 |
| Carter, AE | 1 |
| Eban, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Incidence of COVID-19 Test Conversion in Post-surgical Patients[NCT04392323] | 111 participants (Actual) | Interventional | 2020-05-13 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for hydroxychloroquine and Postoperative Complications
| Article | Year |
|---|---|
Recommendations for eye care during the alarm state by the coronavirus disease pandemic COVID-19.
Topics: Antimalarials; Asymptomatic Diseases; Betacoronavirus; Blood Safety; Chloroquine; Contact Lenses; Co | 2020 |
Cardiac manifestations of Q fever infection: case series and a review of the literature.
Topics: Adult; Anti-Bacterial Agents; Antirheumatic Agents; Aortic Coarctation; Aortic Valve Insufficiency; | 2013 |
[Critical evaluation of the usefulness of drugs inhibiting platelet function in the prevention of postoperative deep venous thrombosis and in ischemic cardiopathy].
Topics: Anticoagulants; Aspirin; Clofibrate; Coronary Disease; Dipyridamole; Fibrinolytic Agents; Flurbiprof | 1980 |
[Prevention of postoperative thrombo-embolic complications. The principal methods, other than low-dose heparin].
Topics: Anticoagulants; Dextrans; Dipyridamole; Femoral Neck Fractures; Heparin; Hip Joint; Humans; Hydroxyc | 1977 |
New developments in the detection and prevention of venous thromboembolism.
Topics: Aspirin; Clothing; Dextrans; Electric Stimulation Therapy; Fibrinolytic Agents; Heparin; Hip Joint; | 1979 |
[Prevention of thrombosis and embolism in digestive surgery].
Topics: Anticoagulants; Aspirin; Coumarins; Dextrans; Digestive System Surgical Procedures; Dipyridamole; He | 1979 |
Platelet inhibitors in the treatment of thrombosis.
Topics: Adult; Aged; Arteriovenous Shunt, Surgical; Aspirin; Blood Platelets; Clinical Trials as Topic; Clof | 1978 |
[Treatment with antiplatelet drugs. Current status of knowledge].
Topics: Aspirin; Blood Platelet Disorders; Cerebrovascular Disorders; Clofibrate; Coronary Disease; Dextrans | 1979 |
The prevention of postoperative deep vein thrombosis.
Topics: Adult; Aspirin; Atmospheric Pressure; Clinical Trials as Topic; Dextrans; Electric Stimulation; Ethy | 1975 |
9 trials available for hydroxychloroquine and Postoperative Complications
| Article | Year |
|---|---|
The effectiveness of intermittent plantar venous compression in prevention of deep venous thrombosis after total hip arthroplasty.
Topics: Aged; Bandages; Female; Femoral Vein; Foot; Gravity Suits; Heparin; Hip Prosthesis; Humans; Hydroxyc | 1993 |
Prevention of postoperative thrombosis by aspirin.
Topics: Aspirin; Clinical Trials as Topic; Drug Evaluation; Hip Joint; Humans; Hydroxychloroquine; Joint Pro | 1977 |
Failure of orally administered hydroxychloroquine sulphate to prevent venous thromboembolism following elective hip operations.
Topics: Administration, Oral; Aged; Arthroplasty; Body Weight; Clinical Trials as Topic; Double-Blind Method | 1977 |
Platelet inhibitors in the treatment of thrombosis.
Topics: Adult; Aged; Arteriovenous Shunt, Surgical; Aspirin; Blood Platelets; Clinical Trials as Topic; Clof | 1978 |
Prevention of venous thromboembolism by administration of hydroxychloroquine. A preliminary report.
Topics: Adult; Aged; Clinical Trials as Topic; Fractures, Bone; Humans; Hydroxychloroquine; Leg; Middle Aged | 1976 |
The prevention of postoperative deep vein thrombosis.
Topics: Adult; Aspirin; Atmospheric Pressure; Clinical Trials as Topic; Dextrans; Electric Stimulation; Ethy | 1975 |
The current status of platelet suppressive drugs in the treatment of thrombosis.
Topics: Aged; Arteriovenous Shunt, Surgical; Aspirin; Blood Platelets; Cardiac Catheterization; Cell Surviva | 1975 |
Platelet-inhibiting drugs in the prevention of clinical thrombotic disease (third of three parts).
Topics: Anticoagulants; Aspirin; Clinical Trials as Topic; Clofibrate; Dipyridamole; Drug Evaluation; Fibrin | 1975 |
Prevention of postoperative deep venous thrombosis in legs by orally administered hydroxychloroquine sulphate.
Topics: Administration, Oral; Aged; Female; Fibrinogen; Humans; Hydroxychloroquine; Iodine Radioisotopes; Le | 1974 |
11 other studies available for hydroxychloroquine and Postoperative Complications
| Article | Year |
|---|---|
Bariatric Surgical Practice During the Initial Phase of COVID-19 Outbreak.
Topics: Adult; Anti-Retroviral Agents; Betacoronavirus; Coronavirus Infections; Cough; COVID-19; Dyspnea; Fa | 2020 |
Coronavirus disease 2019 infection in patients with recent cardiac surgery: does chronic anticoagulant therapy have a protective effect?
Topics: Aged; Anti-Infective Agents; Anticoagulants; Azithromycin; Cardiac Surgical Procedures; Combined Mod | 2020 |
Mucormycosis after Coronavirus disease 2019 infection in a heart transplant recipient - Case report and review of literature.
Topics: Aged; Anti-Infective Agents; Bacteremia; Catheter-Related Infections; Coinfection; Combined Modality | 2021 |
Lower Genital Tract Dysplasia in Female Solid Organ Transplant Recipients.
Topics: Adult; Early Detection of Cancer; Female; Genital Neoplasms, Female; Humans; Hydroxychloroquine; Inc | 2019 |
INDIVIDUAL TOXIC REACTIONS TO MUSHROOMS.
Topics: Agaricales; Foodborne Diseases; Hydroxychloroquine; Lupus Erythematosus, Discoid; Lupus Erythematosu | 1964 |
The prevention of postoperative venous thromboembolism.
Topics: Anticoagulants; Aspirin; Dextrans; Heparin; Humans; Hydroxychloroquine; Leg; Postoperative Complicat | 1978 |
Hydroxychloroquine in prophylaxis of pulmonary embolism following hip arthroplasty.
Topics: Dextrans; Drug Therapy, Combination; Hip Joint; Hip Prosthesis; Humans; Hydroxychloroquine; Postoper | 1979 |
Pulmonary embolism and its prophylaxis following the Charnley total hip replacement.
Topics: Blood Transfusion; Early Ambulation; Heparin; Hip; Humans; Hydroxychloroquine; Infusions, Parenteral | 1977 |
Venous thrombosis after total hip replacement. Combined monitoring as a guide for prophylaxis and treatment.
Topics: Arthroplasty; Blood Platelets; Hip Joint; Humans; Hydroxychloroquine; Joint Prosthesis; Plethysmogra | 1976 |
Hydroxychloroquine sulfate in prevention of thromboembolic phenomena in surgical patients.
Topics: Hematocrit; Humans; Hydroxychloroquine; Platelet Aggregation; Postoperative Complications; Surgical | 1975 |
Hydroxychloroquine sulfate prophylaxis for pulmonary embolism for patients with low-friction arthroplasty.
Topics: Dextrans; Hip Prosthesis; Humans; Hydroxychloroquine; Postoperative Complications; Pulmonary Embolis | 1986 |