hydroxychloroquine has been researched along with Porphyrias in 14 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Porphyrias: A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydroxychloroquine and phlebotomy were compared in the treatment of porphyria cutanea tarda (PCT)." | 9.05 | Hydroxychloroquine versus phlebotomy in the treatment of porphyria cutanea tarda. ( Bessone, E; Cainelli, T; Cantoni, L; Di Padova, C; Gori, G; Marchesi, L; Podenzani, SA; Rovagnati, P, 1983) |
| "High-dose hydroxychloroquine is rarely used in the treatment of porphyria cutanea tarda (PCT)." | 7.68 | High-dose hydroxychloroquine treatment of porphyria cutanea tarda. ( Petersen, CS; Thomsen, K, 1992) |
| "Six patients with skin changes and urinary porphyrin excretion patterns characteristic for porphyria cutanea tarda were treated with hydroxychloroquine sulfate therapy." | 7.66 | Hydroxychloroquine treatment of porphyria cutanea tarda. ( Levitt, L; Malkinson, FD, 1980) |
| "Hydroxychloroquine and phlebotomy were compared in the treatment of porphyria cutanea tarda (PCT)." | 5.05 | Hydroxychloroquine versus phlebotomy in the treatment of porphyria cutanea tarda. ( Bessone, E; Cainelli, T; Cantoni, L; Di Padova, C; Gori, G; Marchesi, L; Podenzani, SA; Rovagnati, P, 1983) |
| "High-dose hydroxychloroquine is rarely used in the treatment of porphyria cutanea tarda (PCT)." | 3.68 | High-dose hydroxychloroquine treatment of porphyria cutanea tarda. ( Petersen, CS; Thomsen, K, 1992) |
| "Six patients with skin changes and urinary porphyrin excretion patterns characteristic for porphyria cutanea tarda were treated with hydroxychloroquine sulfate therapy." | 3.66 | Hydroxychloroquine treatment of porphyria cutanea tarda. ( Levitt, L; Malkinson, FD, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (92.86) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| HARBER, LC | 2 |
| FLEISCHER, AS | 1 |
| BAER, RL | 1 |
| Marchesi, L | 2 |
| Di Padova, C | 2 |
| Cainelli, T | 2 |
| Reseghetti, A | 1 |
| Di Padova, F | 1 |
| Rovagnati, P | 2 |
| Cantoni, L | 2 |
| Bickers, DR | 1 |
| Gori, G | 1 |
| Podenzani, SA | 1 |
| Bessone, E | 1 |
| Tanenbaum, L | 1 |
| Tuffanelli, DL | 1 |
| Malkinson, FD | 2 |
| Levitt, L | 1 |
| Wise, RD | 1 |
| Baler, GR | 1 |
| Petersen, CS | 1 |
| Thomsen, K | 2 |
| Belaïch, S | 1 |
| Crickx, B | 1 |
| Picard, C | 1 |
| Lazareth, I | 1 |
| Fegueux, S | 1 |
| Barthélémy, H | 1 |
| Bilbault, P | 1 |
| Bundino, S | 1 |
| Topi, GC | 1 |
| Zina, AM | 1 |
| D'Allessandro Gandolfo, L | 1 |
| Goerz, G | 1 |
| Bolsen, K | 1 |
| Seuwen, P | 1 |
| Schmitter, H | 1 |
| Merk, H | 1 |
| Lissner, R | 1 |
| Malina, L | 1 |
| Schmidt, H | 1 |
| Snitker, G | 1 |
| Lintrup, J | 1 |
1 review available for hydroxychloroquine and Porphyrias
| Article | Year |
|---|---|
Antimalarial agents. Chloroquine, hydroxychloroquine, and quinacrine.
Topics: Abnormalities, Drug-Induced; Anti-Inflammatory Agents; Chloroquine; DNA; Eye Diseases; Female; Hemat | 1980 |
2 trials available for hydroxychloroquine and Porphyrias
| Article | Year |
|---|---|
A comparative trial of desferrioxamine and hydroxychloroquine for treatment of porphyria cutanea tarda in alcoholic patients.
Topics: Adult; Alcoholism; Clinical Trials as Topic; Deferoxamine; Ferritins; Humans; Hydroxychloroquine; Ir | 1984 |
Hydroxychloroquine versus phlebotomy in the treatment of porphyria cutanea tarda.
Topics: Adult; Aged; Bloodletting; Humans; Hydroxychloroquine; Liver Diseases; Male; Middle Aged; Porphyrias | 1983 |
11 other studies available for hydroxychloroquine and Porphyrias
| Article | Year |
|---|---|
ERYTHROPOIETIC PROTOPORPHYRIA AND PHOTOHEMOLYSIS.
Topics: Blood Chemical Analysis; Child; Erythrocytes; Hemolysis; Humans; Hydroa Vacciniforme; Hydroxychloroq | 1964 |
Porphyria and pseudoporphyria.
Topics: Alcoholism; Bloodletting; Female; Furosemide; Humans; Hydroxychloroquine; Kidney Failure, Chronic; M | 1984 |
Hydroxychloroquine treatment of porphyria cutanea tarda.
Topics: Adult; Coproporphyrins; Female; Humans; Hydroxychloroquine; Iron; Liver Diseases; Male; Middle Aged; | 1980 |
Ferrous iron and porphyria cutanea tarda.
Topics: Female; Humans; Hydroxychloroquine; Iron; Middle Aged; Porphyrias | 1977 |
Porphyria precipitated by hydroxychloroquine treatment of systemic lupus erythematosus.
Topics: Female; Humans; Hydroxychloroquine; Lupus Erythematosus, Systemic; Middle Aged; Porphyrias | 1976 |
High-dose hydroxychloroquine treatment of porphyria cutanea tarda.
Topics: Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Female; Follow-Up Studies; Humans; Hyd | 1992 |
[Porphyria cutanea tarda associated with pure cutaneous dermatomyositis].
Topics: Dermatomyositis; Hand Dermatoses; Humans; Hydroxychloroquine; Male; Middle Aged; Porphyrias; Skin Di | 1989 |
Hepatoerythropoietic porphyria.
Topics: Child; Erythropoiesis; Humans; Hydroxychloroquine; Liver Diseases; Male; Porphyrias | 1987 |
Effects of chloroquine and hydroxychloroquine on the hexachlorobenzene-induced porphyria in rats.
Topics: Animals; Chlorobenzenes; Chloroquine; Female; Hexachlorobenzene; Hydroxychloroquine; Porphyrias; Rat | 1986 |
Treatment of chronic hepatic porphyria (PCT).
Topics: Bloodletting; Chloroquine; Humans; Hydroxychloroquine; Liver Diseases; Porphyrias | 1986 |
Erythropoietic protoporphyria. A clinical study based on 29 cases in 14 families.
Topics: Adolescent; Adult; Age Factors; Aged; Biopsy; Child; Child, Preschool; Cholelithiasis; Erythrocytes; | 1974 |