Page last updated: 2024-10-28

hydroxychloroquine and Poisoning

hydroxychloroquine has been researched along with Poisoning in 5 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Poisoning: Used with drugs, chemicals, and industrial materials for human or animal poisoning, acute or chronic, whether the poisoning is accidental, occupational, suicidal, by medication error, or by environmental exposure.

Research Excerpts

ExcerptRelevanceReference
"On the basis of our systematic review and analysis, the EXTRIP workgroup recommends against using extracorporeal methods to enhance elimination of these drugs in patients with severe chloroquine or quinine poisoning."9.05Extracorporeal Treatment for Chloroquine, Hydroxychloroquine, and Quinine Poisoning: Systematic Review and Recommendations from the EXTRIP Workgroup. ( Alhatali, B; Berling, I; Ghannoum, M; Gosselin, S; Hoffman, RS; King, JD; Lavergne, V; Nolin, TD; Roberts, DM; Shepherd, G; Wilson, G, 2020)
"Toxic effects of hydroxychloroquine, like chloroquine, include membrane stabilization and hypokalemia, which is correlated with the severity of the overdose."7.73[Acute hydroxychloroquine poisoning. The danger of rapid or excessive correction of initial hypokalemia]. ( Baud, F; Deye, N; Guerrier, G; Mégarbane, B; Résière, D; Sonneville, R, 2005)
"On the basis of our systematic review and analysis, the EXTRIP workgroup recommends against using extracorporeal methods to enhance elimination of these drugs in patients with severe chloroquine or quinine poisoning."5.05Extracorporeal Treatment for Chloroquine, Hydroxychloroquine, and Quinine Poisoning: Systematic Review and Recommendations from the EXTRIP Workgroup. ( Alhatali, B; Berling, I; Ghannoum, M; Gosselin, S; Hoffman, RS; King, JD; Lavergne, V; Nolin, TD; Roberts, DM; Shepherd, G; Wilson, G, 2020)
"Hydroxychloroquine (HCQ) poisoning is a life-threatening but treatable toxic ingestion."4.02Utility of Hypertonic Saline and Diazepam in COVID-19-Related Hydroxychloroquine Toxicity. ( Becker, JS; Fenves, AZ; Hayes, BD; Hyppolite, G; Khosrowjerdi, S; Mahan, KM; North, CM; Sinden, D; Stearns, DA, 2021)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Berling, I1
King, JD1
Shepherd, G1
Hoffman, RS1
Alhatali, B1
Lavergne, V1
Roberts, DM1
Gosselin, S1
Wilson, G1
Nolin, TD1
Ghannoum, M1
Mahan, KM1
Hayes, BD1
North, CM1
Becker, JS1
Fenves, AZ1
Hyppolite, G1
Khosrowjerdi, S1
Sinden, D1
Stearns, DA1
Soichot, M1
Mégarbane, B2
Houzé, P1
Chevillard, L1
Fonsart, J1
Baud, FJ1
Laprévote, O1
Bourgogne, E1
DALLEY, RA1
HAINSWORTH, D1
Résière, D1
Sonneville, R1
Guerrier, G1
Deye, N1
Baud, F1

Reviews

1 review available for hydroxychloroquine and Poisoning

ArticleYear
Extracorporeal Treatment for Chloroquine, Hydroxychloroquine, and Quinine Poisoning: Systematic Review and Recommendations from the EXTRIP Workgroup.
    Journal of the American Society of Nephrology : JASN, 2020, Volume: 31, Issue:10

    Topics: Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Female; Humans; Hydroxychlor

2020

Other Studies

4 other studies available for hydroxychloroquine and Poisoning

ArticleYear
Utility of Hypertonic Saline and Diazepam in COVID-19-Related Hydroxychloroquine Toxicity.
    The Journal of emergency medicine, 2021, Volume: 60, Issue:3

    Topics: Adult; COVID-19 Drug Treatment; Diazepam; Electrocardiography; Emergency Service, Hospital; Heart Bl

2021
Development, validation and clinical application of a LC-MS/MS method for the simultaneous quantification of hydroxychloroquine and its active metabolites in human whole blood.
    Journal of pharmaceutical and biomedical analysis, 2014, Volume: 100

    Topics: Adult; Antimalarials; Biotransformation; Calibration; Chromatography, Liquid; Drug Monitoring; Drug

2014
FATAL PLAQUENIL POISONING.
    Journal - Forensic Science Society, 1965, Volume: 5, Issue:2

    Topics: Adolescent; Forensic Medicine; Hydroxychloroquine; Poisoning; Toxicology

1965
[Acute hydroxychloroquine poisoning. The danger of rapid or excessive correction of initial hypokalemia].
    Presse medicale (Paris, France : 1983), 2005, Jul-23, Volume: 34, Issue:13

    Topics: Adult; Antimalarials; Female; Humans; Hydroxychloroquine; Hypokalemia; Poisoning; Risk Factors; Suic

2005