hydroxychloroquine has been researched along with Plica Syndrome in 13 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Studies of the efficacy of hydroxychloroquine in rheumatoid arthritis have had methodological flaws and have failed to produce definitive results." | 9.08 | A randomized trial of hydroxychloroquine in early rheumatoid arthritis: the HERA Study. ( , 1995) |
| "Synovitis is prevalent in OA and is associated with pain." | 6.78 | Hydroxychloroquine effectiveness in reducing symptoms of hand osteoarthritis (HERO): study protocol for a randomized controlled trial. ( Adamson, J; Arden, NK; Birrell, F; Cockayne, S; Conaghan, PG; Dickson, J; Doherty, M; Dziedzic, KS; Grainger, A; Hewitt, CE; Kingsbury, SR; O'Neill, TW; Scott, DL; Tharmanathan, P; Torgerson, DJ; Vincent, TL; Wakefield, RJ; Watt, FE, 2013) |
| "Hydroxychloroquine was effective in 6 of the 8 patients treated; it was well tolerated by all patients." | 5.29 | Hydroxychloroquine in the treatment of erosive osteoarthritis. ( Bryant, LR; Carpenter, MT; des Rosier, KF, 1995) |
| "Studies of the efficacy of hydroxychloroquine in rheumatoid arthritis have had methodological flaws and have failed to produce definitive results." | 5.08 | A randomized trial of hydroxychloroquine in early rheumatoid arthritis: the HERA Study. ( , 1995) |
| "Synovitis is prevalent in OA and is associated with pain." | 2.78 | Hydroxychloroquine effectiveness in reducing symptoms of hand osteoarthritis (HERO): study protocol for a randomized controlled trial. ( Adamson, J; Arden, NK; Birrell, F; Cockayne, S; Conaghan, PG; Dickson, J; Doherty, M; Dziedzic, KS; Grainger, A; Hewitt, CE; Kingsbury, SR; O'Neill, TW; Scott, DL; Tharmanathan, P; Torgerson, DJ; Vincent, TL; Wakefield, RJ; Watt, FE, 2013) |
| "Disabling pansclerotic morphea of childhood (DPMC) is a rare subtype of juvenile localized scleroderma (JLS) characterized by pansclerosis mainly affecting children under the age of 14." | 2.61 | Challenges in the diagnosis and treatment of disabling pansclerotic morphea of childhood: case-based review. ( Cox, A; Heaton, V; Munro, J; Renton, WD; Samuel, C; Soh, HJ, 2019) |
| "Hydroxychloroquine was effective in 6 of the 8 patients treated; it was well tolerated by all patients." | 1.29 | Hydroxychloroquine in the treatment of erosive osteoarthritis. ( Bryant, LR; Carpenter, MT; des Rosier, KF, 1995) |
| "Aspirin remains the cornerstone of treatment for juvenile arthritis, although tolmetin may be more effective in controlling the fever of systemic-onset disease." | 1.27 | Treatment of juvenile arthritis. ( Baum, J, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (23.08) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 7 (53.85) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Campochiaro, C | 1 |
| Atay, S | 1 |
| Clark, KEN | 1 |
| Ong, V | 1 |
| Denton, CP | 1 |
| Soh, HJ | 1 |
| Samuel, C | 1 |
| Heaton, V | 1 |
| Renton, WD | 1 |
| Cox, A | 1 |
| Munro, J | 1 |
| Kingsbury, SR | 1 |
| Tharmanathan, P | 1 |
| Adamson, J | 1 |
| Arden, NK | 1 |
| Birrell, F | 1 |
| Cockayne, S | 1 |
| Dickson, J | 1 |
| Doherty, M | 1 |
| Dziedzic, KS | 1 |
| Grainger, A | 1 |
| Hewitt, CE | 1 |
| O'Neill, TW | 1 |
| Scott, DL | 1 |
| Vincent, TL | 1 |
| Wakefield, RJ | 1 |
| Watt, FE | 1 |
| Torgerson, DJ | 1 |
| Conaghan, PG | 1 |
| Dhaon, P | 1 |
| Das, S | 1 |
| Sharma, A | 1 |
| Wakhlu, A | 1 |
| Goel, MM | 1 |
| Yang, DH | 1 |
| Chang, DM | 1 |
| Lai, JH | 1 |
| Huang, GS | 1 |
| Chang, WC | 1 |
| Hou, TY | 1 |
| Ansemant, T | 1 |
| Celard, M | 1 |
| Tavernier, C | 1 |
| Maillefert, JF | 1 |
| Delahaye, F | 1 |
| Ornetti, P | 1 |
| Lebeaux, D | 1 |
| Francès, C | 1 |
| Barete, S | 1 |
| Wechsler, B | 1 |
| Dubourg, O | 1 |
| Renoux, J | 1 |
| Maisonobe, T | 1 |
| Benveniste, O | 1 |
| Gatfossé, M | 1 |
| Bourgeois, P | 1 |
| Amoura, Z | 1 |
| Cacoub, P | 1 |
| Piette, JC | 1 |
| Sène, D | 1 |
| Mozziconacci, P | 1 |
| Hayem, F | 1 |
| Guy-Grand, D | 1 |
| Baum, J | 1 |
| Bryant, LR | 1 |
| des Rosier, KF | 1 |
| Carpenter, MT | 1 |
| Murphy, M | 1 |
| Carmichael, AJ | 1 |
2 reviews available for hydroxychloroquine and Plica Syndrome
| Article | Year |
|---|---|
Challenges in the diagnosis and treatment of disabling pansclerotic morphea of childhood: case-based review.
Topics: Antirheumatic Agents; Biological Products; Biopsy; Child, Preschool; Contracture; Edema; Hematopoiet | 2019 |
Rheumatoid arthritis.
Topics: Antigen-Antibody Reactions; Arthritis, Juvenile; Arthritis, Rheumatoid; Aspirin; Biopsy; Chloroquine | 1973 |
2 trials available for hydroxychloroquine and Plica Syndrome
| Article | Year |
|---|---|
Hydroxychloroquine effectiveness in reducing symptoms of hand osteoarthritis (HERO): study protocol for a randomized controlled trial.
Topics: Activities of Daily Living; Analgesics; Arthralgia; Clinical Protocols; Costs and Cost Analysis; Dou | 2013 |
A randomized trial of hydroxychloroquine in early rheumatoid arthritis: the HERA Study.
Topics: Adult; Aged; Arthritis, Rheumatoid; Double-Blind Method; Female; Follow-Up Studies; Humans; Hydroxyc | 1995 |
9 other studies available for hydroxychloroquine and Plica Syndrome
| Article | Year |
|---|---|
Autoimmunity and immunodeficiency at the crossroad: autoimmune disorders as the presenting feature of selective IgM deficiency.
Topics: Adult; Aftercare; Antirheumatic Agents; Autoimmune Diseases; Humans; Hydroxychloroquine; Iloprost; I | 2019 |
Rheumatoid nodulosis with extra-articular cyst synovitis.
Topics: Antirheumatic Agents; Biopsy; Bursitis; Female; Hand Bones; Humans; Hydroxychloroquine; Middle Aged; | 2015 |
Remitting seronegative symmetrical synovitis with pitting edema following acute intracranial hemorrhage.
Topics: Aged, 80 and over; Antirheumatic Agents; Edema; Glucocorticoids; Humans; Hydroxychloroquine; Intracr | 2011 |
Whipple's disease endocarditis following anti-TNF therapy for atypical rheumatoid arthritis.
Topics: Anti-Bacterial Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Biopsy; Diagnosis, Differential; | 2010 |
Eosinophilic fasciitis (Shulman disease): new insights into the therapeutic management from a series of 34 patients.
Topics: Adult; Aged; Antirheumatic Agents; Azathioprine; Colchicine; Drug Therapy, Combination; Eosinophilia | 2012 |
[Chronic oligoarthritis in children].
Topics: Arthritis, Juvenile; Child; Child, Preschool; Chronic Disease; Female; Glucocorticoids; Humans; Hydr | 1967 |
Treatment of juvenile arthritis.
Topics: Adolescent; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Juvenile; Aspirin; Child; | 1983 |
Hydroxychloroquine in the treatment of erosive osteoarthritis.
Topics: Antirheumatic Agents; Female; Hand; Humans; Hydroxychloroquine; Osteoarthritis; Outcome Assessment, | 1995 |
Fatal toxic epidermal necrolysis associated with hydroxychloroquine.
Topics: Adult; Antirheumatic Agents; Fatal Outcome; Female; Humans; Hydroxychloroquine; Stevens-Johnson Synd | 2001 |