hydroxychloroquine has been researched along with Parkinson Disease in 2 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hedya, SA | 1 |
| Safar, MM | 1 |
| Bahgat, AK | 1 |
| Ju, UH | 1 |
| Liu, FC | 1 |
| Lin, CS | 1 |
| Huang, WY | 1 |
| Lin, TY | 1 |
| Shen, CH | 1 |
| Chou, YC | 1 |
| Lin, CL | 1 |
| Lin, KT | 1 |
| Kao, CH | 1 |
| Chen, CH | 1 |
| Yang, TY | 1 |
2 other studies available for hydroxychloroquine and Parkinson Disease
| Article | Year |
|---|---|
Hydroxychloroquine antiparkinsonian potential: Nurr1 modulation versus autophagy inhibition.
Topics: Animals; Antiparkinson Agents; Apoptosis; Autophagy; Disease Models, Animal; Glycogen Synthase Kinas | 2019 |
Risk of Parkinson disease in Sjögren syndrome administered ineffective immunosuppressant therapies: A nationwide population-based study.
Topics: Adult; Aged; Anti-Inflammatory Agents; Antirheumatic Agents; Comorbidity; Female; Humans; Hydroxychl | 2019 |