hydroxychloroquine has been researched along with Ototoxicity in 5 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Ototoxicity: Damage to the EAR or its function secondary to exposure to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The suggested dose of chloroquine for COVID-19 infection is considerably higher than the usual dosage for malaria treatment; therefore, it is plausible that the ototoxic effects will be greater." | 6.66 | Clinical Implications of Chloroquine and Hydroxychloroquine Ototoxicity for COVID-19 Treatment: A Mini-Review. ( Baguley, DM; Kasbekar, AV; Prayuenyong, P, 2020) |
| "Aim of this paper is to remind the risk of ototoxicity when using chloroquine and hydroxychloroquine, in particular as prophylactic agents against SARS-CoV-2, during the pandemic." | 3.96 | Ototoxicity prevention during the SARS-CoV-2 (COVID-19) emergency. ( Ciorba, A; Hatzopoulos, S; Pelucchi, S; Skarżyński, PH, 2020) |
| " The suggested dose of chloroquine for COVID-19 infection is considerably higher than the usual dosage for malaria treatment; therefore, it is plausible that the ototoxic effects will be greater." | 2.66 | Clinical Implications of Chloroquine and Hydroxychloroquine Ototoxicity for COVID-19 Treatment: A Mini-Review. ( Baguley, DM; Kasbekar, AV; Prayuenyong, P, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 5 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Prayuenyong, P | 1 |
| Kasbekar, AV | 1 |
| Baguley, DM | 1 |
| Saniasiaya, J | 1 |
| Kulasegarah, J | 1 |
| Davis, SN | 1 |
| Wu, P | 1 |
| Camci, ED | 1 |
| Simon, JA | 1 |
| Rubel, EW | 1 |
| Raible, DW | 1 |
| Ciorba, A | 1 |
| Skarżyński, PH | 1 |
| Pelucchi, S | 1 |
| Hatzopoulos, S | 1 |
| Gonçalves, LF | 1 |
| Patatt, FSA | 1 |
| de Paiva, KM | 1 |
| Haas, P | 1 |
2 reviews available for hydroxychloroquine and Ototoxicity
| Article | Year |
|---|---|
Clinical Implications of Chloroquine and Hydroxychloroquine Ototoxicity for COVID-19 Treatment: A Mini-Review.
Topics: Antimalarials; Antiviral Agents; Chloroquine; COVID-19 Drug Treatment; Emergencies; Hearing Loss; Hu | 2020 |
Ototoxic effects of hydroxychloroquine.
Topics: Hearing Loss; Humans; Hydroxychloroquine; Ototoxicity | 2021 |
3 other studies available for hydroxychloroquine and Ototoxicity
| Article | Year |
|---|---|
Auditory Cinchonism in COVID Era.
Topics: Antiviral Agents; Azithromycin; Betacoronavirus; Coronavirus Infections; COVID-19; COVID-19 Drug Tre | 2020 |
Chloroquine kills hair cells in zebrafish lateral line and murine cochlear cultures: Implications for ototoxicity.
Topics: Animals; Antiviral Agents; Cell Survival; Cells, Cultured; Chloroquine; Hair Cells, Auditory; Hydrox | 2020 |
Ototoxicity prevention during the SARS-CoV-2 (COVID-19) emergency.
Topics: Antiviral Agents; Chloroquine; COVID-19 Drug Treatment; Humans; Hydroxychloroquine; Ototoxicity; Pan | 2020 |