hydroxychloroquine has been researched along with Osteosarcoma in 2 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Osteosarcoma: A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gustafson, DL | 1 |
| Viola, LO | 1 |
| Towers, CG | 1 |
| Das, S | 1 |
| Duval, DL | 1 |
| Van Eaton, KM | 1 |
| O'Farrill, JS | 1 |
| Gordon, N | 1 |
1 review available for hydroxychloroquine and Osteosarcoma
| Article | Year |
|---|---|
Autophagy in osteosarcoma.
Topics: Animals; Antimetabolites, Antineoplastic; Autophagy; Bone and Bones; Bone Neoplasms; Cell Line, Tumo | 2014 |
1 other study available for hydroxychloroquine and Osteosarcoma
| Article | Year |
|---|---|
Sensitivity of osteosarcoma cell lines to autophagy inhibition as determined by pharmacologic and genetic manipulation.
Topics: Animals; Antineoplastic Agents; Autophagy; Cell Line, Tumor; Dog Diseases; Dogs; Humans; Hydroxychlo | 2023 |