hydroxychloroquine has been researched along with Osteoarthritis of Knee in 4 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydroxychloroquine treatment did not alter the serum levels of CCL2, CXCL8, CXCL9 or CXCL10 in patients with OA of the knees, although increased serum levels correlated with aging for all subjects, including controls." | 3.85 | CCL2, CXCL8, CXCL9 and CXCL10 serum levels increase with age but are not altered by treatment with hydroxychloroquine in patients with osteoarthritis of the knees. ( Abramo, C; Almeida, CS; Bonfante, HL; Grunewald, STF; Levy, RA; Teixeira, HC, 2017) |
| "Hydroxychloroquine (HCQ), which has shown its effectiveness in rheumatoid arthritis, has been trialed for the treatment of OA; however, its efficacy and safety remain unclear." | 2.82 | Efficacy and safety of hydroxychloroquine in osteoarthritis: a systematic review and meta-analysis of randomized controlled trials. ( Antony, B; Das, S; Dissanayaka, T; Kotlo, A; Singh, A; Wang, Z, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, YH | 1 |
| Singh, A | 1 |
| Kotlo, A | 1 |
| Wang, Z | 1 |
| Dissanayaka, T | 1 |
| Das, S | 1 |
| Antony, B | 1 |
| Tuure, L | 1 |
| Hämäläinen, M | 1 |
| Moilanen, T | 1 |
| Moilanen, E | 1 |
| Bonfante, HL | 1 |
| Almeida, CS | 1 |
| Abramo, C | 1 |
| Grunewald, STF | 1 |
| Levy, RA | 1 |
| Teixeira, HC | 1 |
1 review available for hydroxychloroquine and Osteoarthritis of Knee
| Article | Year |
|---|---|
Efficacy and safety of hydroxychloroquine in osteoarthritis: a systematic review and meta-analysis of randomized controlled trials.
Topics: Humans; Hydroxychloroquine; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain; Randomized Controlled T | 2022 |
3 other studies available for hydroxychloroquine and Osteoarthritis of Knee
| Article | Year |
|---|---|
Efficacy of hydroxychloroquine for knee osteoarthritis.
Topics: Antirheumatic Agents; Humans; Hydroxychloroquine; Osteoarthritis, Knee | 2022 |
Aurothiomalate inhibits the expression of mPGES-1 in primary human chondrocytes.
Topics: Antirheumatic Agents; Chondrocytes; Dexamethasone; Dinoprostone; Enzyme-Linked Immunosorbent Assay; | 2015 |
CCL2, CXCL8, CXCL9 and CXCL10 serum levels increase with age but are not altered by treatment with hydroxychloroquine in patients with osteoarthritis of the knees.
Topics: Age Factors; Aged; Aging; Antirheumatic Agents; Biomarkers; Case-Control Studies; Chemokine CCL2; Ch | 2017 |