hydroxychloroquine has been researched along with Orphan Diseases in 9 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Orphan Diseases: Rare diseases that have not been well studied.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hiccups are involuntary diaphragmatic muscle contractions with early glottis closure terminating inspiration." | 1.62 | Persistent hiccup: A rare presentation of COVID-19. ( Bakheet, N; El-Shazly, M; Fouad, R; Hussin, W; Kassem, AM, 2021) |
| "We describe a case of MAS secondary to systemic lupus erythematosus in a young female that responded well to rituximab in lieu of etoposide." | 1.46 | Novel use of rituximab in macrophage activation syndrome secondary to systemic lupus erythematosus. ( Junga, Z; Keith, M; Stitt, R; Tracy, C, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Chastagner, M | 1 |
| Shourik, J | 1 |
| Jachiet, M | 1 |
| Battistella, M | 1 |
| Lefevre, G | 1 |
| Gibier, JB | 1 |
| Aubert, H | 1 |
| Musquer, M | 1 |
| Descamps, V | 1 |
| Deschamps, L | 1 |
| Chosidow, O | 1 |
| Ortonne, N | 1 |
| Groh, M | 1 |
| Bernier, M | 1 |
| Jullien, D | 1 |
| Chasset, F | 1 |
| Staumont-Salle, D | 1 |
| Bouaziz, JD | 1 |
| Kanitakis, J | 1 |
| Villani, AP | 1 |
| Bakheet, N | 1 |
| Fouad, R | 1 |
| Kassem, AM | 1 |
| Hussin, W | 1 |
| El-Shazly, M | 1 |
| Vinay, K | 1 |
| Sawatkar, G | 1 |
| Dogra, S | 1 |
| Saikia, UN | 1 |
| Junga, Z | 1 |
| Stitt, R | 1 |
| Tracy, C | 1 |
| Keith, M | 1 |
| Kweon, SM | 1 |
| Koh, JH | 1 |
| Lee, HN | 1 |
| Kim, E | 1 |
| So, MW | 1 |
| Shin, HJ | 1 |
| Young Choi, H | 1 |
| Lee, SG | 1 |
| Günther, C | 2 |
| Hillebrand, M | 1 |
| Brunk, J | 1 |
| Lee-Kirsch, MA | 2 |
| Mireku, KA | 1 |
| Glover, MH | 1 |
| Davis, L | 1 |
| Canavan, T | 1 |
| Sidorsky, T | 1 |
| Doan, LT | 1 |
| Ricardo-Gonzalez, RR | 1 |
| Shen, G | 1 |
| Rosenblum, MD | 1 |
| Meurer, M | 1 |
| Stein, A | 1 |
| Viehweg, A | 1 |
1 review available for hydroxychloroquine and Orphan Diseases
| Article | Year |
|---|---|
Treatment of Eosinophilic Annular Erythema: Retrospective multicenter study and literature review.
Topics: Adrenal Cortex Hormones; Dapsone; Eosinophilia; Erythema; Humans; Hydroxychloroquine; Multicenter St | 2022 |
8 other studies available for hydroxychloroquine and Orphan Diseases
| Article | Year |
|---|---|
Persistent hiccup: A rare presentation of COVID-19.
Topics: Baclofen; Biomarkers; COVID-19; COVID-19 Testing; Fever; Hiccup; Humans; Hydroxychloroquine; Male; M | 2021 |
Systemic lupus erythematosus with Degos disease: role of dermatoscopy in diagnosis.
Topics: Adolescent; Aspirin; Biopsy, Needle; Dermoscopy; Drug Therapy, Combination; Female; Humans; Hydroxyc | 2017 |
Novel use of rituximab in macrophage activation syndrome secondary to systemic lupus erythematosus.
Topics: Antineoplastic Agents, Immunological; Antirheumatic Agents; Diagnosis, Differential; Etoposide; Fema | 2017 |
Primary Sjogren syndrome diagnosed simultaneously with localized amyloidosis of the lacrimal gland: A case report.
Topics: Amyloidosis; Antirheumatic Agents; Biopsy; Female; Humans; Hydroxychloroquine; Lacrimal Apparatus; M | 2018 |
Systemic involvement in TREX1-associated familial chilblain lupus.
Topics: Chilblains; Exodeoxyribonucleases; Follow-Up Studies; Genetic Predisposition to Disease; Heterozygot | 2013 |
Tender macules and papules on the toes.
Topics: Administration, Topical; Chilblains; Clobetasol; Dermatologic Agents; Diagnosis, Differential; Femal | 2014 |
A case of Wong-type dermatomyositis with concomitant anti-MDA5 features.
Topics: Biomarkers; Biopsy, Needle; DEAD-box RNA Helicases; Dermatomyositis; Drug Therapy, Combination; Elec | 2014 |
Familial chilblain lupus--a monogenic form of cutaneous lupus erythematosus due to a heterozygous mutation in TREX1.
Topics: Adolescent; Aspirin; Biopsy, Needle; Chronic Disease; Disease Progression; Drug Therapy, Combination | 2009 |