hydroxychloroquine has been researched along with Necrosis in 9 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Histiocytic necrotizing lymphadenitis (Kikuchi's disease) is an uncommon disease of the cervical lymph nodes occurring in young women, commonly associated with various auto-immune or infectious diseases." | 2.39 | [Kikuchi syndrome, Hashimoto thyroiditis and lupus serology. Apropos of a case]. ( Anzieu, B; Bousquet, E; Brousset, P; Dubarry, B; Duffaut, M; Massip, P; Tubéry, M, 1996) |
| "Troxis necrosis is a novel mechanism for drug-induced hepatitis, including immunomodulatory medications including a monoclonal anti-TWEAK antibody and Cellcept and Plaquenil, two widely used immunosuppression/anti-rejection medications." | 1.42 | Troxis necrosis, a novel mechanism for drug-induced hepatitis secondary to immunomodulatory therapy. ( Datta, A; Fleishman, W; French, SW; Karpouzas, G; Penunuri, A; Wei, CH, 2015) |
| "Hydroxychloroquine has rarely been associated with TEN, with one case proving fatal." | 1.40 | Hydroxychloroquine-induced fatal toxic epidermal necrolysis complicated by angioinvasive rhizopus. ( Cameron, MC; Dominguez, A; Word, AP, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Alruwaili, M | 2 |
| Jarrar, B | 1 |
| Jarrar, Q | 1 |
| Goh, KW | 1 |
| Moshawih, S | 1 |
| Ardianto, C | 1 |
| Ming, LC | 1 |
| Cameron, MC | 1 |
| Word, AP | 1 |
| Dominguez, A | 1 |
| Wang, Y | 1 |
| Tai, X | 1 |
| Zhang, L | 1 |
| Liu, Y | 1 |
| Gao, H | 1 |
| Chen, J | 1 |
| Shi, K | 1 |
| Zhang, Q | 1 |
| Zhang, Z | 1 |
| He, Q | 1 |
| Wei, CH | 1 |
| Penunuri, A | 1 |
| Karpouzas, G | 1 |
| Fleishman, W | 1 |
| Datta, A | 1 |
| French, SW | 1 |
| He, A | 1 |
| Kwatra, SG | 1 |
| Kazi, N | 1 |
| Sweren, RJ | 1 |
| Elmore, S | 1 |
| Lanning, L | 1 |
| Allison, N | 1 |
| Vallant, M | 1 |
| Nyska, A | 1 |
| Bousquet, E | 1 |
| Tubéry, M | 1 |
| Brousset, P | 1 |
| Anzieu, B | 1 |
| Dubarry, B | 1 |
| Massip, P | 1 |
| Duffaut, M | 1 |
| Getz, MA | 1 |
| Subramanian, R | 1 |
| Logemann, T | 1 |
| Ballantyne, F | 1 |
| Bonelli, U | 1 |
1 review available for hydroxychloroquine and Necrosis
| Article | Year |
|---|---|
[Kikuchi syndrome, Hashimoto thyroiditis and lupus serology. Apropos of a case].
Topics: Adolescent; Cortisone; Female; Histiocytosis; Humans; Hydroxychloroquine; Lupus Erythematosus, Syste | 1996 |
8 other studies available for hydroxychloroquine and Necrosis
| Article | Year |
|---|---|
Hydroxychloroquine Toxicity in the Vital Organs of the Body:
Topics: Animals; COVID-19; COVID-19 Drug Treatment; Humans; Hydroxychloroquine; Liver; Male; Necrosis; Rats | 2023 |
Hydroxychloroquine-induced fatal toxic epidermal necrolysis complicated by angioinvasive rhizopus.
Topics: Adult; Antirheumatic Agents; Blood Vessels; Facial Dermatoses; Fatal Outcome; Female; Humans; Hydrox | 2014 |
A novel antitumour strategy using bidirectional autophagic vesicles accumulation via initiative induction and the terminal restraint of autophagic flux.
Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Cell | 2015 |
Troxis necrosis, a novel mechanism for drug-induced hepatitis secondary to immunomodulatory therapy.
Topics: Adult; Chemical and Drug Induced Liver Injury; Enzyme Inhibitors; Humans; Hydroxychloroquine; Immuno | 2015 |
Atypical lymphocytic lobular panniculitis: an overlap condition with features of subcutaneous panniculitis-like T-cell lymphoma and lupus profundus.
Topics: Antirheumatic Agents; Biopsy; Diagnosis, Differential; Female; Humans; Hydroxychloroquine; Lymphoma, | 2016 |
The transduction of rat submandibular glands by an adenoviral vector carrying the human growth hormone gene is associated with limited and reversible changes at the infusion site.
Topics: Adenoviridae; Animals; Antirheumatic Agents; Female; Fibrosis; Gene Transfer Techniques; Genetic Vec | 2006 |
Acute necrotizing eosinophilic myocarditis as a manifestation of severe hypersensitivity myocarditis. Antemortem diagnosis and successful treatment.
Topics: Adult; Amitriptyline; Cardiomyopathy, Dilated; Drug Hypersensitivity; Eosinophilia; Female; Humans; | 1991 |
[Use of hydroxychloroquine sulfate in the supportive therapy of ulcerative necrotic disglobulinemic angiodermatitis].
Topics: Agammaglobulinemia; Aged; Humans; Hydroxychloroquine; Leg; Middle Aged; Necrosis; Purpura; Skin; Ski | 1969 |