Page last updated: 2024-10-28

hydroxychloroquine and Methemoglobinemia

hydroxychloroquine has been researched along with Methemoglobinemia in 4 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Methemoglobinemia: The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"Methemoglobinemia is a rare disorder of the blood in which there is an increase in methemoglobin, which occurs when hemoglobin is present in the oxidized form."1.56Unexplained Methemoglobinemia in Coronavirus Disease 2019: A Case Report. ( Bloom, A; Faisal, H; Gaber, AO, 2020)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's4 (100.00)2.80

Authors

AuthorsStudies
Naymagon, L1
Berwick, S1
Kessler, A1
Lancman, G1
Gidwani, U1
Troy, K1
Faisal, H1
Bloom, A1
Gaber, AO1
Choo, SY1
Sahu, KK1
Mishra, AK1
Mishra, K1

Other Studies

4 other studies available for hydroxychloroquine and Methemoglobinemia

ArticleYear
The emergence of methemoglobinemia amidst the COVID-19 pandemic.
    American journal of hematology, 2020, Volume: 95, Issue:8

    Topics: Azithromycin; Betacoronavirus; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Diabetes M

2020
Unexplained Methemoglobinemia in Coronavirus Disease 2019: A Case Report.
    A&A practice, 2020, Volume: 14, Issue:9

    Topics: Acute Kidney Injury; Aged; Antibodies, Monoclonal, Humanized; Antioxidants; Ascorbic Acid; Betacoron

2020
Rapidly rising methemoglobinemia in a patient with severe COVID-19 treated successfully with red cell exchange transfusion.
    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy, 2021, Volume: 25, Issue:5

    Topics: Anti-Bacterial Agents; Azithromycin; COVID-19; Erythrocyte Transfusion; Humans; Hydroxychloroquine;

2021
Methemoglobinemia in COVID-19.
    The American journal of the medical sciences, 2021, Volume: 362, Issue:2

    Topics: Adult; Aged; Antirheumatic Agents; COVID-19; COVID-19 Drug Treatment; Humans; Hydroxychloroquine; Ma

2021