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hydroxychloroquine and Metabolic Syndrome

hydroxychloroquine has been researched along with Metabolic Syndrome in 6 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Metabolic Syndrome: A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome include ABDOMINAL OBESITY; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state.

Research Excerpts

ExcerptRelevanceReference
"To determine the relationship between current hydroxychloroquine (HCQ) use and 2 indicators of glycemic control, fasting glucose and insulin sensitivity, in nondiabetic women with systemic lupus erythematosus (SLE) or rheumatoid arthritis (RA)."7.76Hydroxychloroquine and glycemia in women with rheumatoid arthritis and systemic lupus erythematosus. ( Elliott, JR; Kao, AH; Kuller, L; Manzi, S; Penn, SK; Schott, LL; Toledo, FG; Wasko, MC, 2010)
"To determine the relationship between current hydroxychloroquine (HCQ) use and 2 indicators of glycemic control, fasting glucose and insulin sensitivity, in nondiabetic women with systemic lupus erythematosus (SLE) or rheumatoid arthritis (RA)."3.76Hydroxychloroquine and glycemia in women with rheumatoid arthritis and systemic lupus erythematosus. ( Elliott, JR; Kao, AH; Kuller, L; Manzi, S; Penn, SK; Schott, LL; Toledo, FG; Wasko, MC, 2010)
"Hydroxychloroquine (HCQ) use was found as a protective factor for CVD."1.43Metabolic syndrome is not only a risk factor for cardiovascular diseases in systemic lupus erythematosus but is also associated with cumulative organ damage: a cross-sectional analysis of 311 patients. ( Alpay-Kanıtez, N; Aral, O; Artim-Esen, B; Demir, S; Erer, B; Gül, A; İnanç, M; Kamalı, S; Öcal, L; Omma, A; Pehlivan, Ö; Şahinkaya, Y, 2016)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Sharma, M1
Kumar, M1
Dutta, D1
Soh, MC1
Nelson-Piercy, C1
Westgren, M1
McCowan, L1
Pasupathy, D1
Demir, S1
Artim-Esen, B1
Şahinkaya, Y1
Pehlivan, Ö1
Alpay-Kanıtez, N1
Omma, A1
Erer, B1
Kamalı, S1
Gül, A1
Aral, O1
Öcal, L1
İnanç, M1
Penn, SK1
Kao, AH1
Schott, LL1
Elliott, JR1
Toledo, FG1
Kuller, L1
Manzi, S1
Wasko, MC1
Sahebari, M1
Goshayeshi, L1
Mirfeizi, Z1
Rezaieyazdi, Z1
Hatef, MR1
Ghayour-Mobarhan, M1
Akhlaghi, S1
Sahebkar, A1
Ferns, GA1
Liu, SY1
Guo, JY1
Zhang, L1
Liu, ZS1
Zheng, ZH1
Cheng, GY1
Gao, GM1
Zhang, X1
Liu, GZ1
Zeng, XF1

Reviews

1 review available for hydroxychloroquine and Metabolic Syndrome

ArticleYear
Do adverse pregnancy outcomes contribute to accelerated cardiovascular events seen in young women with systemic lupus erythematosus?
    Lupus, 2017, Volume: 26, Issue:13

    Topics: Adult; Antiphospholipid Syndrome; Cardiovascular Diseases; Female; Humans; Hydroxychloroquine; Lupus

2017

Other Studies

5 other studies available for hydroxychloroquine and Metabolic Syndrome

ArticleYear
Hydroxychloroquine in diabetes and dyslipidaemia: primum non nocere.
    Diabetic medicine : a journal of the British Diabetic Association, 2020, Volume: 37, Issue:8

    Topics: Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Dyslipidemias; Enzyme Inhibitors; Human

2020
Metabolic syndrome is not only a risk factor for cardiovascular diseases in systemic lupus erythematosus but is also associated with cumulative organ damage: a cross-sectional analysis of 311 patients.
    Lupus, 2016, Volume: 25, Issue:2

    Topics: Adult; Antibodies, Antiphospholipid; Antirheumatic Agents; Cardiovascular Diseases; Cross-Sectional

2016
Hydroxychloroquine and glycemia in women with rheumatoid arthritis and systemic lupus erythematosus.
    The Journal of rheumatology, 2010, Volume: 37, Issue:6

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Blood Glucose; Cross-Sectional Studies; Diabetes Mellit

2010
Investigation of the association between metabolic syndrome and disease activity in rheumatoid arthritis.
    TheScientificWorldJournal, 2011, Jun-09, Volume: 11

    Topics: Adult; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Body Mass Index; Femal

2011
[Incidence of metabolic syndrome in systemic lupus erythematosus and its influence by glucocorticoids].
    Zhonghua nei ke za zhi, 2012, Volume: 51, Issue:6

    Topics: Adolescent; Adult; Case-Control Studies; Female; Glucocorticoids; Humans; Hydroxychloroquine; Incide

2012