hydroxychloroquine has been researched along with Malaria, Falciparum in 4 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Malaria, Falciparum: Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Eleven volunteers received chloroquine in usually curative doses on a three-day schedule during acute clinical malaria attacks." | 3.64 | STUDIES ON A STRAIN OF CHLOROQUINE-RESISTANT PLASMODIUM FALCIPARUM FROM THAILAND. ( ALVING, AS; BREWER, GJ; MILLAR, JW; POWELL, RD, 1964) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sargin, G | 1 |
| Yavaşoğlu, Sİ | 1 |
| Yavasoglu, I | 1 |
| LOUGHLIN, EH | 1 |
| RICE, JB | 1 |
| WELLS, HS | 1 |
| RAPPAPORT, I | 1 |
| JOSEPH, AA | 1 |
| POWELL, RD | 1 |
| BREWER, GJ | 1 |
| ALVING, AS | 1 |
| MILLAR, JW | 1 |
| Easterbrook, M | 1 |
4 other studies available for hydroxychloroquine and Malaria, Falciparum
| Article | Year |
|---|---|
Is Coronavirus Disease 2019 (COVID-19) seen less in countries more exposed to Malaria?
Topics: Africa South of the Sahara; Anti-Inflammatory Agents; Antigen Presentation; Antimalarials; Antiviral | 2020 |
The treatment of Plasmodium falciparum malaria with a single dose antimalarial; a preliminary report of the use of hydroxychloroquine, 7-chloro-4(4-(N-ethyl-N-B-hydroxyethylamino)-1-methylbutylamino)-quinoline diphosphate.
Topics: Antimalarials; Chloroquine; Humans; Hydroxychloroquine; Malaria; Malaria, Falciparum; Quinolines | 1952 |
STUDIES ON A STRAIN OF CHLOROQUINE-RESISTANT PLASMODIUM FALCIPARUM FROM THAILAND.
Topics: Amodiaquine; Antimalarials; Asia, Southeastern; Biomedical Research; Chloroquine; Drug Resistance; D | 1964 |
Long-term course of antimalarial maculopathy after cessation of treatment.
Topics: Chloroquine; Follow-Up Studies; Humans; Hydroxychloroquine; Longitudinal Studies; Macula Lutea; Mala | 1992 |