Page last updated: 2024-10-28

hydroxychloroquine and Lipodystrophy

hydroxychloroquine has been researched along with Lipodystrophy in 5 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Lipodystrophy: A collection of heterogenous conditions resulting from defective LIPID METABOLISM and characterized by ADIPOSE TISSUE atrophy. Often there is redistribution of body fat resulting in peripheral fat wasting and central adiposity. They include generalized, localized, congenital, and acquired lipodystrophy.

Research Excerpts

ExcerptRelevanceReference
"This study aimed to investigate the relationship between centrifugal lipodystrophy (CLD) and lupus erythematosus panniculitis (LEP), and the efficacy and safety of hydroxychloroquine (HCQ) for treating CLD in children."8.12Centrifugal lipodystrophy on a spectrum with lupus erythematosus panniculitis in children and efficacy and safety of hydroxychloroquine: A clinicopathological study. ( Gu, Y; Li, Y; Ling, B; Lu, Z; Qiu, Y; Xu, Q; Yao, Z; Yu, H, 2022)
"This study aimed to investigate the relationship between centrifugal lipodystrophy (CLD) and lupus erythematosus panniculitis (LEP), and the efficacy and safety of hydroxychloroquine (HCQ) for treating CLD in children."4.12Centrifugal lipodystrophy on a spectrum with lupus erythematosus panniculitis in children and efficacy and safety of hydroxychloroquine: A clinicopathological study. ( Gu, Y; Li, Y; Ling, B; Lu, Z; Qiu, Y; Xu, Q; Yao, Z; Yu, H, 2022)
"Lipoatrophic panniculitis (LP) is a rare disease of childhood characterized by eruption of tender erythematous nodules and plaques followed by circumferential bands of lipoatrophy often seen on the arms and legs."1.36Lipoatrophic panniculitis: case report and review of the literature. ( Edmonson, MB; Gottam, CC; Hinshaw, MA; Shen, LY; Teng, JM; Williams, GP, 2010)
"Lipodystrophy was seen in 10/33 (30."1.33Twelve years experience of juvenile dermatomyositis in North India. ( Bansal, A; Singh, S, 2006)
"She was diagnosed as having lupus panniculitis."1.32Lupus panniculitis with combined features of dermatomyositis resulting in severe lipoatrophy. ( Cho, KH; Jo, SJ; Yoo, JY, 2004)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's1 (20.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Xu, Q1
Qiu, Y1
Lu, Z1
Yu, H1
Ling, B1
Li, Y1
Gu, Y1
Yao, Z1
Garnica-Cruz, P1
Durán-Mckinster, C1
Orozco-Covarrubias, ML1
Saéz de Ocariz, MDM1
Palacios-López, CG1
García-Romero, MT1
Shen, LY1
Edmonson, MB1
Williams, GP1
Gottam, CC1
Hinshaw, MA1
Teng, JM1
Yoo, JY1
Jo, SJ1
Cho, KH1
Singh, S1
Bansal, A1

Other Studies

5 other studies available for hydroxychloroquine and Lipodystrophy

ArticleYear
Centrifugal lipodystrophy on a spectrum with lupus erythematosus panniculitis in children and efficacy and safety of hydroxychloroquine: A clinicopathological study.
    Dermatologic therapy, 2022, Volume: 35, Issue:11

    Topics: Alopecia; Child; Female; Humans; Hydroxychloroquine; Infant; Lipodystrophy; Male; Panniculitis; Pann

2022
Acquired localized lipoatrophy in children is frequently caused by preceding injections: a retrospective study of 12 patients.
    International journal of dermatology, 2020, Volume: 59, Issue:5

    Topics: Anti-Bacterial Agents; Biopsy; Child; Child, Preschool; Female; Follow-Up Studies; Glucocorticoids;

2020
Lipoatrophic panniculitis: case report and review of the literature.
    Archives of dermatology, 2010, Volume: 146, Issue:8

    Topics: Ankle; Anti-Inflammatory Agents; Antirheumatic Agents; Biopsy; Child; Drug Therapy, Combination; Hum

2010
Lupus panniculitis with combined features of dermatomyositis resulting in severe lipoatrophy.
    The Journal of dermatology, 2004, Volume: 31, Issue:7

    Topics: Biopsy, Needle; Child; Dermatomyositis; Female; Follow-Up Studies; Humans; Hydroxychloroquine; Immun

2004
Twelve years experience of juvenile dermatomyositis in North India.
    Rheumatology international, 2006, Volume: 26, Issue:6

    Topics: Adolescent; Age of Onset; Azathioprine; Calcinosis; Child; Child, Preschool; Deglutition Disorders;

2006