hydroxychloroquine has been researched along with Lichen Planus in 33 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Lichen Planus: An inflammatory, pruritic disease of the skin and mucous membranes, which can be either generalized or localized. It is characterized by distinctive purplish, flat-topped papules having a predilection for the trunk and flexor surfaces. The lesions may be discrete or coalesce to form plaques. Histologically, there is a saw-tooth pattern of epidermal hyperplasia and vacuolar alteration of the basal layer of the epidermis along with an intense upper dermal inflammatory infiltrate composed predominantly of T-cells. Etiology is unknown.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydroxychloroquine sulfate (Plaquenil), an antimalarial agent, was evaluated in an open trial (10 patients) for its ability to improve oral lichen planus." | 9.07 | Hydroxychloroquine sulfate (Plaquenil) improves oral lichen planus: An open trial. ( Eisen, D, 1993) |
| "Hydroxychloroquine sulfate (Plaquenil), an antimalarial agent, was evaluated in an open trial (10 patients) for its ability to improve oral lichen planus." | 5.07 | Hydroxychloroquine sulfate (Plaquenil) improves oral lichen planus: An open trial. ( Eisen, D, 1993) |
| "Two patients with dermatological conditions developed retinal toxicity after treatment with hydroxychloroquine that exceeded dosing recommendations." | 1.48 | Hydroxychloroquine retinal toxicity in two patients with dermatological conditions. ( Baker, C; Kowalski, T; Mack, HG, 2018) |
| "One patient had hair loss of the upper cutaneous lip." | 1.46 | Frontal fibrosing alopecia among men: A clinicopathologic study of 7 cases. ( Camilleri, MJ; Chaudhry, HM; Tolkachjov, SN; Torgerson, RR, 2017) |
| "FFA is an increasingly common form of scarring hair loss, but the origin remains unknown." | 1.39 | Frontal fibrosing alopecia: a retrospective review of 19 patients seen at Duke University. ( Bazakas, A; Ladizinski, B; Olsen, EA; Selim, MA, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.03) | 18.7374 |
| 1990's | 2 (6.06) | 18.2507 |
| 2000's | 1 (3.03) | 29.6817 |
| 2010's | 17 (51.52) | 24.3611 |
| 2020's | 12 (36.36) | 2.80 |
| Authors | Studies |
|---|---|
| Vastarella, M | 1 |
| Cantelli, M | 1 |
| Nappa, P | 1 |
| Fabbrocini, G | 1 |
| Ocampo-Garza, SS | 1 |
| Kępińska, K | 1 |
| Jałowska, M | 1 |
| Bowszyc-Dmochowska, M | 1 |
| Klein, EJ | 1 |
| Karim, M | 1 |
| Lo Sicco, K | 1 |
| Shapiro, J | 1 |
| Platais, C | 1 |
| Lalagianni, N | 1 |
| Momen, S | 1 |
| Ormond, M | 1 |
| McParland, H | 1 |
| Setterfield, J | 1 |
| Devjani, S | 1 |
| Ezemma, O | 1 |
| Jothishankar, BA | 1 |
| Kelley, KJ | 1 |
| Senna, M | 1 |
| Orlando, G | 2 |
| Salmaso, R | 1 |
| Piaserico, S | 1 |
| Starace, M | 1 |
| Alessandrini, A | 1 |
| Baraldi, C | 1 |
| Bruni, F | 1 |
| Piraccini, BM | 1 |
| Mostafa, N | 1 |
| Phan, K | 1 |
| Smith, S | 1 |
| Dadkhahfar, S | 1 |
| Araghi, F | 1 |
| Tabary, M | 1 |
| Moravvej, H | 1 |
| Bhanja, DB | 1 |
| Sil, A | 1 |
| Chandra, A | 1 |
| Biswas, SK | 1 |
| Vermeer, HAB | 1 |
| Rashid, H | 1 |
| Esajas, MD | 1 |
| Oldhoff, JM | 1 |
| Horváth, B | 1 |
| Subramanyam, C | 1 |
| Wu, H | 1 |
| Puri, P | 1 |
| Chambers, CJ | 1 |
| Sivamani, RK | 1 |
| Akabane, AL | 1 |
| Smith, GP | 1 |
| Tolkachjov, SN | 1 |
| Chaudhry, HM | 1 |
| Camilleri, MJ | 1 |
| Torgerson, RR | 1 |
| Eyler, JT | 1 |
| Garib, G | 1 |
| Thompson, KR | 1 |
| Dahiya, M | 1 |
| Swan, JW | 1 |
| Kowalski, T | 1 |
| Baker, C | 1 |
| Mack, HG | 1 |
| Wu, CY | 1 |
| Lin, FL | 1 |
| Husein-ElAhmed, H | 1 |
| Gieler, U | 1 |
| Steinhoff, M | 1 |
| Fisher, V | 1 |
| Fernandez, MP | 1 |
| Krejci-Manwaring, J | 1 |
| Gameza, VA | 1 |
| Deleuran, M | 1 |
| Nic Dhonncha, E | 1 |
| Foley, CC | 1 |
| Markham, T | 1 |
| Chiang, C | 1 |
| Sah, D | 1 |
| Cho, BK | 1 |
| Ochoa, BE | 1 |
| Price, VH | 1 |
| Sperling, LC | 1 |
| Nguyen, JV | 1 |
| Donati, A | 1 |
| Assouly, P | 2 |
| Matard, B | 1 |
| Jouanique, C | 1 |
| Reygagne, P | 1 |
| Kluger, N | 1 |
| Agozzino, M | 1 |
| Tosti, A | 1 |
| Barbieri, L | 1 |
| Moscarella, E | 1 |
| Cota, C | 1 |
| Berardesca, E | 1 |
| Ardigò, M | 1 |
| Vashi, N | 1 |
| Newlove, T | 1 |
| Chu, J | 1 |
| Patel, R | 1 |
| Stein, J | 1 |
| Ramírez, P | 1 |
| Feito, M | 1 |
| Sendagorta, E | 1 |
| González-Beato, M | 1 |
| De Lucas, R | 1 |
| Ladizinski, B | 1 |
| Bazakas, A | 1 |
| Selim, MA | 1 |
| Olsen, EA | 1 |
| Ferraro, V | 1 |
| Mantoux, F | 1 |
| Denis, K | 1 |
| Lay-Macagno, MA | 1 |
| Ortonne, JP | 1 |
| Lacour, JP | 1 |
| Albers, SE | 1 |
| Glass, LF | 1 |
| Fenske, NA | 1 |
| Eisen, D | 1 |
| Nagy, E | 1 |
| Szakály, I | 1 |
4 reviews available for hydroxychloroquine and Lichen Planus
| Article | Year |
|---|---|
Frontal Fibrosing Alopecia - a review and a practical guide for clinicians.
Topics: Alopecia; Child, Preschool; Female; Forehead; Humans; Hydroxychloroquine; Lichen Planus; Scalp | 2022 |
Mycophenolate mofetil and lichen planopilaris: systematic review and meta-analysis.
Topics: Humans; Hydroxychloroquine; Immunosuppressive Agents; Lichen Planus; Mycophenolic Acid; Remission In | 2022 |
Lichen planus: a comprehensive evidence-based analysis of medical treatment.
Topics: Administration, Oral; Administration, Topical; Adrenal Cortex Hormones; Antifungal Agents; Calcineur | 2019 |
[Pseudopelade of Brocq].
Topics: Adrenal Cortex Hormones; Alopecia Areata; Dermoscopy; Diagnosis, Differential; Disease Progression; | 2011 |
1 trial available for hydroxychloroquine and Lichen Planus
| Article | Year |
|---|---|
Hydroxychloroquine sulfate (Plaquenil) improves oral lichen planus: An open trial.
Topics: Administration, Oral; Administration, Topical; Adult; Aged; Female; Humans; Hydroxychloroquine; Lich | 1993 |
28 other studies available for hydroxychloroquine and Lichen Planus
| Article | Year |
|---|---|
Efficacy and safety of hydroxychloroquine for the management of lichen planopilaris in a real-life setting.
Topics: Humans; Hydroxychloroquine; Lichen Planus | 2022 |
Response to the study by Collins et al "Retrospective review of adverse events associated with oral hydroxychloroquine use in patients with cicatricial alopecia."
Topics: Alopecia; Cicatrix; Humans; Hydroxychloroquine; Lichen Planus; Retrospective Studies | 2022 |
Efficacy of hydroxychloroquine in oral lichen planus: a retrospective review.
Topics: Humans; Hydroxychloroquine; Lichen Planus; Lichen Planus, Oral; Retrospective Studies | 2023 |
Assessment of hydroxychloroquine use and QT interval duration in female patients with frontal fibrosing alopecia.
Topics: Alopecia; Female; Fibrosis; Humans; Hydroxychloroquine; Lichen Planus | 2023 |
A Case of Secondary Osteoma Cutis Associated with Lichen Planopilaris.
Topics: Alopecia; Bone Diseases, Metabolic; Clobetasol; Female; Glucocorticoids; Humans; Hydroxychloroquine; | 2019 |
Diffuse variants of scalp lichen planopilaris: Clinical, trichoscopic, and histopathologic features of 40 patients.
Topics: 5-alpha Reductase Inhibitors; Administration, Oral; Administration, Topical; Adult; Aged; Alopecia A | 2020 |
Considerations of Managing Lichen Planopilaris With Hydroxychloroquine During the COVID-19 Pandemic.
Topics: Coronavirus Infections; COVID-19; Humans; Hydroxychloroquine; Iran; Lichen Planus; Pandemics; Pneumo | 2020 |
Addisonian-like acrofacial hyperpigmentation following long-term hydroxychloroquine therapy in oral lichen planus.
Topics: Humans; Hydroxychloroquine; Hyperpigmentation; Lichen Planus; Lichen Planus, Oral | 2021 |
The use of hydroxychloroquine as a systemic treatment in erosive lichen planus of the vulva and vagina.
Topics: Female; Humans; Hydroxychloroquine; Lichen Planus; Lichen Planus, Oral; Vagina; Vulva | 2021 |
Lichen planopilaris with significant post-inflammatory pigmentary alteration.
Topics: Adult; Dermatologic Agents; Diagnosis, Differential; Humans; Hydroxychloroquine; Hyperpigmentation; | 2021 |
Adverse cutaneous reactions secondary to hydroxychloroquine in patients with dermatomyositis, lupus erythematosus, and lichen planopilaris.
Topics: Dermatomyositis; Humans; Hydroxychloroquine; Lichen Planus; Lupus Erythematosus, Cutaneous; Lupus Er | 2021 |
Frontal fibrosing alopecia among men: A clinicopathologic study of 7 cases.
Topics: Adult; Aged; Alopecia; Anti-Inflammatory Agents; Cheek; Cicatrix; Clobetasol; Dermatologic Agents; E | 2017 |
Annular atrophic lichen planus responds to hydroxychloroquine and acitretin.
Topics: Acitretin; Aged; Dermatologic Agents; Humans; Hydroxychloroquine; Lichen Planus; Male; Treatment Out | 2017 |
Hydroxychloroquine retinal toxicity in two patients with dermatological conditions.
Topics: Aged; Antimalarials; Female; Humans; Hydroxychloroquine; Lichen Planus; Lichen Sclerosus et Atrophic | 2018 |
A successful combination therapy of tacrolimus, hydroxychloroquine and picosecond laser for lichen planus pigmentosus.
Topics: Administration, Oral; Administration, Topical; Biopsy, Needle; Combined Modality Therapy; Facial Der | 2019 |
Lichen planus mimicking recalcitrant ulcerative psoriasis: when is it time to biopsy?
Topics: Acitretin; Adult; Biopsy; Clobetasol; Dermatologic Agents; Female; Humans; Hydroxychloroquine; Liche | 2013 |
[Frontal fibrosing alopecia is a variant of lichen planopilaris].
Topics: Aged; Alopecia; Enzyme Inhibitors; Female; Humans; Hydroxychloroquine; Lichen Planus | 2015 |
The role of hydroxychloroquine in the treatment of lichen planopilaris: A retrospective case series and review.
Topics: Adult; Aged; Dermatologic Agents; Female; Humans; Hydroxychloroquine; Lichen Planus; Male; Middle Ag | 2017 |
Hydroxychloroquine and lichen planopilaris: efficacy and introduction of Lichen Planopilaris Activity Index scoring system.
Topics: Adult; Alopecia; Cicatrix; Female; Fibrosis; Humans; Hydroxychloroquine; Lichen Planus; Male; Middle | 2010 |
Commentary: treatment of lichen planopilaris: some progress, but a long way to go.
Topics: Adrenal Cortex Hormones; Alopecia; Clinical Trials as Topic; Cyclosporine; Female; Humans; Hydroxych | 2010 |
Clinical and photographic assessment of lichen planopilaris treatment efficacy.
Topics: Alopecia; Humans; Hydroxychloroquine; Lichen Planus; Scalp Dermatoses; Treatment Outcome | 2011 |
Confocal microscopic features of scarring alopecia: preliminary report.
Topics: Aged; Alopecia; Anti-Inflammatory Agents; Clobetasol; Dermatologic Agents; Female; Humans; Hydroxych | 2011 |
Graham-Little-Piccardi-Lassueur syndrome.
Topics: Adult; Alopecia; Axilla; Doxycycline; Female; Groin; Humans; Hydroxychloroquine; Hyperpigmentation; | 2011 |
Childhood actinic lichen planus: successful treatment with antimalarials.
Topics: Antimalarials; Child; Facial Dermatoses; Female; Humans; Hydroxychloroquine; Lichen Planus; Photosen | 2012 |
Frontal fibrosing alopecia: a retrospective review of 19 patients seen at Duke University.
Topics: 5-alpha Reductase Inhibitors; Adult; Aged; Alopecia; Anti-Bacterial Agents; Azasteroids; Cicatrix; D | 2013 |
[Hallucinations during treatment with hydrochloroquine].
Topics: Aged; Dermatologic Agents; Female; Hallucinations; Humans; Hydroxychloroquine; Lichen Planus | 2004 |
Lichen planus subtropicus: direct immunofluorescence findings and therapeutic response to hydroxychloroquine.
Topics: Adult; Female; Humans; Hydrocortisone; Hydroxychloroquine; Lichen Planus; Microscopy, Fluorescence | 1994 |
[Discoid lupus erythematosus or lichen planus?].
Topics: Chloroquine; Diagnosis, Differential; Female; Humans; Hydroxychloroquine; Lichen Planus; Lupus Eryth | 1978 |