Page last updated: 2024-10-28

hydroxychloroquine and Lichen Planus, Oral

hydroxychloroquine has been researched along with Lichen Planus, Oral in 12 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Lichen Planus, Oral: Oral lesions accompanying cutaneous lichen planus or often occurring alone. The buccal mucosa, lips, gingivae, floor of the mouth, and palate are usually affected (in a descending order of frequency). Typically, oral lesions consist of radiating white or gray, velvety, threadlike lines, arranged in a reticular pattern, at the intersection of which there may be minute, white, elevated dots or streaks (Wickham's striae). (Jablonski, Illustrated Dictionary of Dentistry)

Research Excerpts

ExcerptRelevanceReference
" A distinguishing feature of CUS is the low response to conventional corticosteroid therapy and the good outcome with hydroxychloroquine at the dosage of 200 mg/day or higher dosages."2.61Chronic ulcerative stomatitis: A comprehensive review and proposal for diagnostic criteria. ( Azzi, L; Cerati, M; Croveri, F; Lombardo, M; Maurino, V; Olszewska, M; Pellilli, M; Tagliabue, A; Tettamanti, L, 2019)
"Chronic ulcerative stomatitis (CUS) is a mucocutaneous disorder which is characterised by persistent oral mucosal ulceration."2.47Chronic ulcerative stomatitis: a distinct clinical entity? ( Fourie, J; McEachen, SC; van Heerden, WF; van Zyl, A, 2011)
"Hydroxychloroquine or prednisone was used to treat patients randomly."1.40Hydroxychloroquine decreases the upregulated frequencies of Tregs in patients with oral lichen planus. ( Bai, Y; Duan, N; Jiang, H; Li, J; Wang, T; Wang, W; Wang, X; Zhu, Y, 2014)
"Hydroxychloroquine niosomes were designed using different methods of preparation."1.39Hydroxychloroquine niosomes: a new trend in topical management of oral lichen planus. ( Abdullah, H; Bendas, ER; El-Komy, MH; Kassem, MA, 2013)
"Chronic ulcerative stomatitis (CUS) is a recently described condition with specific immunopathologic findings."1.35Chronic ulcerative stomatitis. ( Solomon, LW, 2008)
"Chronic ulcerative stomatitis (CUS) is a mucocutaneous disease primarily involving mucosal surfaces, but occasionally may involve the skin."1.32Chronic ulcerative stomatitis: clinical, histopathologic, and immunopathologic findings. ( Aguirre, A; Costales-Spindler, A; Jividen, GJ; Kumar, V; Neiders, M; Solomon, LW; Zwick, MG, 2003)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (16.67)29.6817
2010's7 (58.33)24.3611
2020's3 (25.00)2.80

Authors

AuthorsStudies
Platais, C1
Lalagianni, N1
Momen, S1
Ormond, M1
McParland, H1
Setterfield, J1
Bhanja, DB1
Sil, A1
Chandra, A1
Biswas, SK1
Vermeer, HAB1
Rashid, H1
Esajas, MD1
Oldhoff, JM1
Horváth, B1
Yeshurun, A1
Bergman, R1
Bathish, N1
Khamaysi, Z1
Azzi, L1
Cerati, M1
Lombardo, M1
Pellilli, M1
Croveri, F1
Maurino, V1
Tagliabue, A1
Tettamanti, L1
Olszewska, M1
Atzori, L1
Robustelli Test, E1
Ferreli, C1
Pilloni, L1
Rongioletti, F1
Jiang, HL1
Wang, WM1
Duan, N2
Jiang, WH1
Wang, X2
Bendas, ER1
Abdullah, H1
El-Komy, MH1
Kassem, MA1
Zhu, Y1
Li, J1
Bai, Y1
Jiang, H1
Wang, T1
Wang, W1
Solomon, LW2
Fourie, J1
van Heerden, WF1
McEachen, SC1
van Zyl, A1
Aguirre, A1
Neiders, M1
Costales-Spindler, A1
Jividen, GJ1
Zwick, MG1
Kumar, V1

Reviews

2 reviews available for hydroxychloroquine and Lichen Planus, Oral

ArticleYear
Chronic ulcerative stomatitis: A comprehensive review and proposal for diagnostic criteria.
    Oral diseases, 2019, Volume: 25, Issue:6

    Topics: Aged; Anti-Inflammatory Agents; Antibodies, Antinuclear; Female; Gingivitis, Necrotizing Ulcerative;

2019
Chronic ulcerative stomatitis: a distinct clinical entity?
    SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging, 2011, Volume: 66, Issue:3

    Topics: Adult; Antirheumatic Agents; Chronic Disease; Cyclosporine; Diagnosis, Differential; Female; Gingivi

2011

Other Studies

10 other studies available for hydroxychloroquine and Lichen Planus, Oral

ArticleYear
Efficacy of hydroxychloroquine in oral lichen planus: a retrospective review.
    The British journal of dermatology, 2023, 03-30, Volume: 188, Issue:4

    Topics: Humans; Hydroxychloroquine; Lichen Planus; Lichen Planus, Oral; Retrospective Studies

2023
Addisonian-like acrofacial hyperpigmentation following long-term hydroxychloroquine therapy in oral lichen planus.
    BMJ case reports, 2021, Jan-28, Volume: 14, Issue:1

    Topics: Humans; Hydroxychloroquine; Hyperpigmentation; Lichen Planus; Lichen Planus, Oral

2021
The use of hydroxychloroquine as a systemic treatment in erosive lichen planus of the vulva and vagina.
    The British journal of dermatology, 2021, Volume: 185, Issue:1

    Topics: Female; Humans; Hydroxychloroquine; Lichen Planus; Lichen Planus, Oral; Vagina; Vulva

2021
Hydroxychloroquine sulphate therapy of erosive oral lichen planus.
    The Australasian journal of dermatology, 2019, Volume: 60, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Creatinine; Exanthema; Female; Humans; Hydroxychloroquine; Hyperpigm

2019
Impressive oral lichen planus progression to invasive squamous cell carcinoma in a three months lapse.
    Oral oncology, 2019, Volume: 90

    Topics: Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cicatrix; Disease Progression; Follow-Up

2019
[Use of 2-DE and MALDI-TOF-MS to screen differentially expressed serum proteins in patients with oral lichen planus before and after hydroxychloroquine treatment].
    Shanghai kou qiang yi xue = Shanghai journal of stomatology, 2013, Volume: 22, Issue:2

    Topics: Apolipoproteins A; Blood Proteins; Electrophoresis, Gel, Two-Dimensional; Humans; Hydroxychloroquine

2013
Hydroxychloroquine niosomes: a new trend in topical management of oral lichen planus.
    International journal of pharmaceutics, 2013, Dec-31, Volume: 458, Issue:2

    Topics: Administration, Topical; Adult; Chemistry, Pharmaceutical; Cholesterol; Double-Blind Method; Drug Ca

2013
Hydroxychloroquine decreases the upregulated frequencies of Tregs in patients with oral lichen planus.
    Clinical oral investigations, 2014, Volume: 18, Issue:8

    Topics: Adult; Female; Humans; Hydroxychloroquine; Lichen Planus, Oral; Male; T-Lymphocytes, Regulatory; Up-

2014
Chronic ulcerative stomatitis.
    Oral diseases, 2008, Volume: 14, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Chronic Disease; Diagnosis, Differential; Female; Gingivitis, Nec

2008
Chronic ulcerative stomatitis: clinical, histopathologic, and immunopathologic findings.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2003, Volume: 96, Issue:6

    Topics: Adult; Aged; Antibodies, Antinuclear; Blotting, Western; Cell Nucleus; Chronic Disease; Diagnosis, D

2003