hydroxychloroquine has been researched along with Leukemia in 2 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, F | 1 |
| Zhang, Z | 1 |
| Leung, WT | 1 |
| Chen, J | 1 |
| Yi, J | 1 |
| Ying, C | 1 |
| Yuan, M | 1 |
| Wang, M | 1 |
| Zhang, N | 1 |
| Qiu, X | 1 |
| Wang, L | 1 |
| Wei, H | 1 |
| Sehgal, AR | 1 |
| Konig, H | 1 |
| Johnson, DE | 1 |
| Tang, D | 1 |
| Amaravadi, RK | 1 |
| Boyiadzis, M | 1 |
| Lotze, MT | 1 |
1 review available for hydroxychloroquine and Leukemia
| Article | Year |
|---|---|
You eat what you are: autophagy inhibition as a therapeutic strategy in leukemia.
Topics: Antineoplastic Agents; Autophagy; Boronic Acids; Bortezomib; Cell Survival; Clinical Trials as Topic | 2015 |
1 other study available for hydroxychloroquine and Leukemia
| Article | Year |
|---|---|
Hydroxychloroquine reverses the drug resistance of leukemic K562/ADM cells by inhibiting autophagy.
Topics: Antibiotics, Antineoplastic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Aut | 2019 |