hydroxychloroquine has been researched along with Leg Ulcer in 5 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Leg Ulcer: Ulceration of the skin and underlying structures of the lower extremity. About 90% of the cases are due to venous insufficiency (VARICOSE ULCER), 5% to arterial disease, and the remaining 5% to other causes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sarcoidosis is a granulomatous multisystemic disease of unclear etiology, which can affect any organ." | 5.37 | [Uncommon cutaneous ulcerative and systemic sarcoidosis. Successful treatment with hydroxychloroquine and compression therapy]. ( Bertsch, HP; Meyersburg, D; Schön, MP; Seitz, CS, 2011) |
| "Sarcoidosis is a granulomatous multisystemic disease of unclear etiology, which can affect any organ." | 1.37 | [Uncommon cutaneous ulcerative and systemic sarcoidosis. Successful treatment with hydroxychloroquine and compression therapy]. ( Bertsch, HP; Meyersburg, D; Schön, MP; Seitz, CS, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Razmi T, M | 1 |
| Jindal, AK | 1 |
| Arora, K | 1 |
| Joshi, V | 1 |
| Suri, D | 1 |
| De, D | 1 |
| Powell, E | 1 |
| Rosen, T | 1 |
| Mevius, H | 1 |
| Quax, RA | 1 |
| Alsma, J | 1 |
| Rozin, AP | 1 |
| Egozi, D | 1 |
| Ramon, Y | 1 |
| Toledano, K | 1 |
| Braun-Moscovici, Y | 1 |
| Markovits, D | 1 |
| Schapira, D | 1 |
| Bergman, R | 1 |
| Melamed, Y | 1 |
| Ullman, Y | 1 |
| Balbir-Gurman, A | 1 |
| Meyersburg, D | 1 |
| Schön, MP | 1 |
| Bertsch, HP | 1 |
| Seitz, CS | 1 |
5 other studies available for hydroxychloroquine and Leg Ulcer
| Article | Year |
|---|---|
Refractory leg ulcers in prolidase deficiency with antiphospholipid antibody positivity responding to aspirin-hydroxychloroquine-vitamin C combination therapy.
Topics: Antibodies, Antiphospholipid; Ascorbic Acid; Aspirin; Humans; Hydroxychloroquine; Leg Ulcer; Prolida | 2020 |
Ulcerative sarcoidosis: a prototypical presentation and review.
Topics: Anti-Inflammatory Agents; Humans; Hydroxychloroquine; Leg Ulcer; Long-Term Care; Male; Middle Aged; | 2017 |
Man With Necrotizing Ulcers on the Leg.
Topics: Adult; Enzyme Inhibitors; Glucocorticoids; Humans; Hydroxychloroquine; Leg Ulcer; Male; Sarcoidosis; | 2016 |
Large leg ulcers due to autoimmune diseases.
Topics: Animals; Antibodies, Monoclonal; Autoimmune Diseases; Azathioprine; Ciprofloxacin; Cyclophosphamide; | 2011 |
[Uncommon cutaneous ulcerative and systemic sarcoidosis. Successful treatment with hydroxychloroquine and compression therapy].
Topics: Antirheumatic Agents; Biopsy; Combined Modality Therapy; Debridement; Diagnosis, Differential; Femal | 2011 |