Page last updated: 2024-10-28

hydroxychloroquine and Kidney Diseases

hydroxychloroquine has been researched along with Kidney Diseases in 10 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.

Research Excerpts

ExcerptRelevanceReference
" For inflammatory arthritis, 79% of experts agreed (first- through fourth-line treatments were MTX, low-dose glucocorticoids, hydroxychloroquine, and rituximab or tocilizumab, respectively)."3.88Treatment Algorithms for Systemic Sclerosis According to Experts. ( Fernández-Codina, A; Pope, JE; Walker, KM, 2018)
" Recommendations were made based on available data, consideration of pharmacokinetic properties (including variability), the dosing and anticipated treatment duration of each regimen in COVID-19 and known toxicities."2.72Recommendations for Dosing of Repurposed COVID-19 Medications in Patients with Renal and Hepatic Impairment. ( Back, D; Boyle, A; Burger, D; Davidson, K; El-Sherif, O; Gibbons, S; Khoo, S; Marra, F; Marzolini, C; Siccardi, M; Smolders, EJ; Sommerville, AJ, 2021)
"In the 1980's, pregnancies in systemic sclerosis (SSc) patients were considered to be at high risk for poor foetal and maternal outcome."2.44[Pregnancy in systemic sclerosis]. ( Bérezné, A; Mouthon, L, 2008)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's1 (10.00)18.2507
2000's2 (20.00)29.6817
2010's4 (40.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Gougis, P1
Fenioux, C1
Funck-Brentano, C1
Veyri, M1
Gligorov, J1
Solas, C1
Spano, JP1
Marra, F1
Smolders, EJ1
El-Sherif, O1
Boyle, A1
Davidson, K1
Sommerville, AJ1
Marzolini, C1
Siccardi, M1
Burger, D1
Gibbons, S1
Khoo, S1
Back, D1
Colla, L1
Diena, D1
Rossetti, M1
Manzione, AM1
Marozio, L1
Benedetto, C1
Biancone, L1
Fernández-Codina, A1
Walker, KM1
Pope, JE1
Sperati, CJ1
Rosenberg, AZ1
Sebastiani, GD1
Prevete, I1
Piga, M1
Iuliano, A1
Bettio, S1
Bortoluzzi, A1
Coladonato, L1
Tani, C1
Spinelli, FR1
Fineschi, I1
Mathieu, A1
Bérezné, A1
Mouthon, L1
Bracamonte, ER1
Kowalewska, J1
Starr, J1
Gitomer, J1
Alpers, CE1
Wallace, DJ1
Harker, LA1
Hirsh, J1
Gent, M1
Genton, E1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effectiveness of ECP in Diffuse Cutaneous Systemic Sclerosis[NCT04986605]Phase 215 participants (Anticipated)Interventional2023-12-01Not yet recruiting
Pragmatic Clinical Trials in Scleroderma[NCT03610217]400 participants (Anticipated)Interventional2018-10-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for hydroxychloroquine and Kidney Diseases

ArticleYear
Recommendations for Dosing of Repurposed COVID-19 Medications in Patients with Renal and Hepatic Impairment.
    Drugs in R&D, 2021, Volume: 21, Issue:1

    Topics: Adenosine Monophosphate; Alanine; Antiviral Agents; Clinical Trials as Topic; COVID-19; COVID-19 Dru

2021
Immunosuppression in pregnant women with renal disease: review of the latest evidence in the biologics era.
    Journal of nephrology, 2018, Volume: 31, Issue:3

    Topics: Azathioprine; Biological Products; Calcineurin Inhibitors; Cyclophosphamide; Directive Counseling; F

2018
[Pregnancy in systemic sclerosis].
    Presse medicale (Paris, France : 1983), 2008, Volume: 37, Issue:11

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antirheumatic Agents; Female; Fetal Diseases; Humans; Hydr

2008
Antimalarial agents and lupus.
    Rheumatic diseases clinics of North America, 1994, Volume: 20, Issue:1

    Topics: Antibodies, Antiphospholipid; Antimalarials; Chloroquine; Female; Humans; Hydroxychloroquine; Kidney

1994
Critical evaluation of platelet-inhibiting drugs in thrombotic disease.
    Progress in hematology, 1975, Volume: 9

    Topics: Arteriosclerosis; Aspirin; Blood Platelets; Cerebrovascular Disorders; Clinical Trials as Topic; Clo

1975

Trials

1 trial available for hydroxychloroquine and Kidney Diseases

ArticleYear
Critical evaluation of platelet-inhibiting drugs in thrombotic disease.
    Progress in hematology, 1975, Volume: 9

    Topics: Arteriosclerosis; Aspirin; Blood Platelets; Cerebrovascular Disorders; Clinical Trials as Topic; Clo

1975

Other Studies

5 other studies available for hydroxychloroquine and Kidney Diseases

ArticleYear
Anticancer drugs and COVID-19 antiviral treatments in patients with cancer: What can we safely use?
    European journal of cancer (Oxford, England : 1990), 2020, Volume: 136

    Topics: Amides; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Agents, Hormonal; A

2020
Treatment Algorithms for Systemic Sclerosis According to Experts.
    Arthritis & rheumatology (Hoboken, N.J.), 2018, Volume: 70, Issue:11

    Topics: Algorithms; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antibodies,

2018
Treatment Algorithms for Systemic Sclerosis According to Experts.
    Arthritis & rheumatology (Hoboken, N.J.), 2018, Volume: 70, Issue:11

    Topics: Algorithms; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antibodies,

2018
Treatment Algorithms for Systemic Sclerosis According to Experts.
    Arthritis & rheumatology (Hoboken, N.J.), 2018, Volume: 70, Issue:11

    Topics: Algorithms; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antibodies,

2018
Treatment Algorithms for Systemic Sclerosis According to Experts.
    Arthritis & rheumatology (Hoboken, N.J.), 2018, Volume: 70, Issue:11

    Topics: Algorithms; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antibodies,

2018
Hydroxychloroquine-induced mimic of renal Fabry disease.
    Kidney international, 2018, Volume: 94, Issue:3

    Topics: Adult; Antirheumatic Agents; Biopsy; Diagnosis, Differential; Fabry Disease; Female; Humans; Hydroxy

2018
Early Lupus Project - A multicentre Italian study on systemic lupus erythematosus of recent onset.
    Lupus, 2015, Volume: 24, Issue:12

    Topics: Adult; Age of Onset; Antibodies, Antinuclear; Antibodies, Antiphospholipid; Arthritis; Female; Human

2015
Iatrogenic phospholipidosis mimicking Fabry disease.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2006, Volume: 48, Issue:5

    Topics: alpha-Galactosidase; Antirheumatic Agents; Diagnosis, Differential; DNA Mutational Analysis; Epithel

2006