Page last updated: 2024-10-28

hydroxychloroquine and Idiopathic Pulmonary Fibrosis

hydroxychloroquine has been researched along with Idiopathic Pulmonary Fibrosis in 2 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Idiopathic Pulmonary Fibrosis: A common interstitial lung disease of unknown etiology, usually occurring between 50-70 years of age. Clinically, it is characterized by an insidious onset of breathlessness with exertion and a nonproductive cough, leading to progressive DYSPNEA. Pathological features show scant interstitial inflammation, patchy collagen fibrosis, prominent fibroblast proliferation foci, and microscopic honeycomb change.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Morlacchi, LC1
Rossetti, V1
Gigli, L1
Amati, F1
Rosso, L1
Aliberti, S1
Nosotti, M1
Blasi, F1
Manning, EP1
Losier, A1
Emeagwali, N1
Ryu, C1
Honiden, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Safety and Immunogenicity of the SARS-CoV2 Vaccine in Solid Organ Transplantation (Lung and / or Liver) Adult Recipients[NCT05116748]200 participants (Anticipated)Observational2021-10-01Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

2 other studies available for hydroxychloroquine and Idiopathic Pulmonary Fibrosis

ArticleYear
COVID-19 in lung transplant recipients: A case series from Milan, Italy.
    Transplant infectious disease : an official journal of the Transplantation Society, 2020, Volume: 22, Issue:6

    Topics: Aged; Anti-Bacterial Agents; Anticoagulants; Blood Gas Analysis; COVID-19; COVID-19 Drug Treatment;

2020
New Applications of Old Drugs as Novel Therapies in Idiopathic Pulmonary Fibrosis. Metformin, Hydroxychloroquine, and Thyroid Hormone.
    American journal of respiratory and critical care medicine, 2019, Jun-15, Volume: 199, Issue:12

    Topics: Bleomycin; Humans; Hydroxychloroquine; Idiopathic Pulmonary Fibrosis; Metformin; Thyroid Hormones

2019