hydroxychloroquine has been researched along with Hypoxia in 19 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The large outbreak of coronavirus disease 2019 (COVID-19) is spreading all over the world rapidly." | 5.62 | Effectiveness of lopinavir/ritonavir on COVID-19-related pneumonia in a child with COVID-19-associated Kawasaki disease. ( Akat, H; Laloglu, F; Orbak, Z, 2021) |
| " In fact, two of the actually used drugs against SARS-CoV2, such as chloroquine and the combination lopinavir/ritonavir, might determine a QT (the time from the start of the Q wave to the end of the T wave) interval prolongation and they show several interactions with antiarrhythmic drugs and antipsychotic medications, making them prone to an increased risk of developing arrhythmias." | 5.12 | COVID-19 and the burning issue of drug interaction: never forget the ECG. ( Cameli, M; Cameli, P; Franchi, F; Mandoli, GE; Menci, D; Mondillo, S; Sciaccaluga, C; Sisti, N; Valente, S, 2021) |
| "Although coronavirus disease 2019 (COVID-19) predominantly disrupts the respiratory system, there is accumulating experience that the disease, particularly in its more severe manifestations, also affects the cardiovascular system." | 2.66 | A current review of COVID-19 for the cardiovascular specialist. ( Bohula, EA; Lang, JP; Morrow, DA; Moura, FA; Siddiqi, HK; Wang, X, 2020) |
| "The large outbreak of coronavirus disease 2019 (COVID-19) is spreading all over the world rapidly." | 1.62 | Effectiveness of lopinavir/ritonavir on COVID-19-related pneumonia in a child with COVID-19-associated Kawasaki disease. ( Akat, H; Laloglu, F; Orbak, Z, 2021) |
| "Novel coronavirus disease 2019 (COVID-19) emerged in late December 2019 in Wuhan, China." | 1.56 | Use of Tocilizumab for COVID-19-Induced Cytokine Release Syndrome: A Cautionary Case Report. ( Bhatt, PJ; Narayanan, N; Radbel, J, 2020) |
| "Hydroxychloroquine (HCQ) has its own side effects, some of which are very serious like acute haemolysis in glucose-6-phosphate dehydrogenase (G6PD) deficient patients." | 1.56 | A case report of serious haemolysis in a glucose-6-phosphate dehydrogenase-deficient COVID-19 patient receiving hydroxychloroquine. ( Clevenbergh, P; De Bels, D; Leemans, S; Mahadeb, B; Maillart, E; Salaouatchi, MT; Van Noten, H; Vandergraesen, T, 2020) |
| "Key words: Coronavirus disease 2019 (COVID-19), Meningoencephalitis, Pneumonia." | 1.56 | A Case of 45-Year Man Who Succumbed to Coronavirus Disease 2019 (COVID-19). ( Khan, MA, 2020) |
| "Methemoglobinemia is a rare disorder of the blood in which there is an increase in methemoglobin, which occurs when hemoglobin is present in the oxidized form." | 1.56 | Unexplained Methemoglobinemia in Coronavirus Disease 2019: A Case Report. ( Bloom, A; Faisal, H; Gaber, AO, 2020) |
| "Diffuse alveolar hemorrhage is an uncommon and often fatal condition in children that is characterized by distinct histopathological etiologies." | 1.51 | Acute pulmonary embolism in a child with ANCA-negative Idiopathic Pulmonary Capillaritis. ( Asseri, AA; Daines, CL; Zeng, Y, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (10.53) | 24.3611 |
| 2020's | 17 (89.47) | 2.80 |
| Authors | Studies |
|---|---|
| Radbel, J | 1 |
| Narayanan, N | 1 |
| Bhatt, PJ | 1 |
| Juusela, A | 1 |
| Nazir, M | 1 |
| Gimovsky, M | 1 |
| Everaert, BR | 1 |
| Muylle, J | 1 |
| Bartholomeus Twickler, T | 1 |
| Maillart, E | 1 |
| Leemans, S | 1 |
| Van Noten, H | 1 |
| Vandergraesen, T | 1 |
| Mahadeb, B | 1 |
| Salaouatchi, MT | 1 |
| De Bels, D | 1 |
| Clevenbergh, P | 1 |
| Lang, JP | 1 |
| Wang, X | 1 |
| Moura, FA | 1 |
| Siddiqi, HK | 1 |
| Morrow, DA | 1 |
| Bohula, EA | 1 |
| Jacquet-Lagrèze, M | 1 |
| Riad, Z | 1 |
| Hugon-Vallet, E | 1 |
| Ferraris, A | 1 |
| Fellahi, JL | 1 |
| Mattioli, M | 1 |
| Fustini, E | 1 |
| Gennarini, S | 1 |
| Mehta, SA | 1 |
| Leonard, J | 1 |
| Labella, P | 1 |
| Cartiera, K | 1 |
| Soomro, I | 1 |
| Neumann, H | 1 |
| Montgomery, RA | 1 |
| Ali, NM | 1 |
| Hiedra, R | 1 |
| Lo, KB | 1 |
| Elbashabsheh, M | 1 |
| Gul, F | 1 |
| Wright, RM | 1 |
| Albano, J | 1 |
| Azmaiparashvili, Z | 1 |
| Patarroyo Aponte, G | 1 |
| Khan, MA | 2 |
| Choi, NH | 1 |
| Silver, ES | 1 |
| Fremed, M | 1 |
| Liberman, L | 1 |
| Sciaccaluga, C | 1 |
| Cameli, M | 1 |
| Menci, D | 1 |
| Mandoli, GE | 1 |
| Sisti, N | 1 |
| Cameli, P | 1 |
| Franchi, F | 1 |
| Mondillo, S | 1 |
| Valente, S | 1 |
| Patel, M | 1 |
| Gangemi, A | 1 |
| Marron, R | 1 |
| Chowdhury, J | 1 |
| Yousef, I | 1 |
| Zheng, M | 1 |
| Mills, N | 1 |
| Tragesser, L | 1 |
| Giurintano, J | 1 |
| Gupta, R | 1 |
| Gordon, M | 1 |
| Rali, P | 1 |
| D'Alonso, G | 1 |
| Fleece, D | 1 |
| Zhao, H | 1 |
| Patlakh, N | 1 |
| Criner, G | 1 |
| Faisal, H | 1 |
| Bloom, A | 1 |
| Gaber, AO | 1 |
| Rodriguez-Garcia, JL | 1 |
| Sanchez-Nievas, G | 1 |
| Arevalo-Serrano, J | 1 |
| Garcia-Gomez, C | 1 |
| Jimenez-Vizuete, JM | 1 |
| Martinez-Alfaro, E | 1 |
| Brusasco, C | 1 |
| Corradi, F | 1 |
| Di Domenico, A | 1 |
| Raggi, F | 1 |
| Timossi, G | 1 |
| Santori, G | 1 |
| Brusasco, V | 1 |
| Orbak, Z | 1 |
| Laloglu, F | 1 |
| Akat, H | 1 |
| Asseri, AA | 1 |
| Zeng, Y | 1 |
| Daines, CL | 1 |
| Rajagopala, S | 1 |
| Singh, N | 1 |
| Gupta, K | 1 |
| Gupta, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Tocilizumab: A Therapeutic Cache Against the Treatment of Severe Cases of COVID-19[NCT04560205] | Phase 1 | 50 participants (Anticipated) | Interventional | 2020-05-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for hydroxychloroquine and Hypoxia
| Article | Year |
|---|---|
A current review of COVID-19 for the cardiovascular specialist.
Topics: Adenosine Monophosphate; Alanine; Antimalarials; Antiviral Agents; Betacoronavirus; Biomarkers; Card | 2020 |
Left ventricular dysfunction in COVID-19: A diagnostic issue.
Topics: Azithromycin; Betacoronavirus; Biomarkers; Coronavirus Infections; COVID-19; Cytokine Release Syndro | 2020 |
COVID-19 and the burning issue of drug interaction: never forget the ECG.
Topics: Adenosine Monophosphate; Alanine; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Antiviral | 2021 |
Pulmonary amyloidosis in Sjogren's syndrome: a case report and systematic review of the literature.
Topics: Adrenal Cortex Hormones; Adult; Amyloidosis; Anti-Bacterial Agents; Antitubercular Agents; Biopsy; E | 2010 |
15 other studies available for hydroxychloroquine and Hypoxia
| Article | Year |
|---|---|
Use of Tocilizumab for COVID-19-Induced Cytokine Release Syndrome: A Cautionary Case Report.
Topics: Adult; Aged; Anti-Infective Agents; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Azi | 2020 |
Two cases of coronavirus 2019-related cardiomyopathy in pregnancy.
Topics: Adult; Anti-Arrhythmia Agents; Antibodies, Monoclonal, Humanized; Anticonvulsants; Blood Gas Analysi | 2020 |
Emerging cardiological issues during the COVID-19 pandemic.
Topics: Antiviral Agents; Arrhythmias, Cardiac; Betacoronavirus; Coronary Artery Disease; Coronavirus Infect | 2020 |
A case report of serious haemolysis in a glucose-6-phosphate dehydrogenase-deficient COVID-19 patient receiving hydroxychloroquine.
Topics: Aged; Azithromycin; Betacoronavirus; Blood Transfusion; Continuous Renal Replacement Therapy; Corona | 2020 |
Heart transplant recipient patient with COVID-19 treated with tocilizumab.
Topics: Anti-Bacterial Agents; Antibodies, Monoclonal, Humanized; Anticoagulants; Cardiomyopathy, Dilated; C | 2020 |
Outpatient management of kidney transplant recipients with suspected COVID-19-Single-center experience during the New York City surge.
Topics: Acute Kidney Injury; Ambulatory Care; Anti-Bacterial Agents; Antibodies, Monoclonal, Humanized; Azit | 2020 |
The use of IV vitamin C for patients with COVID-19: a case series.
Topics: Administration, Intravenous; Aged; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Anti | 2020 |
A Case of 45-Year Man Who Succumbed to Coronavirus Disease 2019 (COVID-19).
Topics: Anti-Bacterial Agents; Anticoagulants; Betacoronavirus; Clinical Laboratory Techniques; Coronavirus; | 2020 |
COVID-19 reveals Brugada pattern in an adolescent patient.
Topics: Antiviral Agents; Brugada Syndrome; C-Reactive Protein; Chest Pain; Consanguinity; Cough; COVID-19; | 2020 |
Retrospective analysis of high flow nasal therapy in COVID-19-related moderate-to-severe hypoxaemic respiratory failure.
Topics: Adrenal Cortex Hormones; Aged; Anti-Bacterial Agents; Antibodies, Monoclonal, Humanized; Antirheumat | 2020 |
Unexplained Methemoglobinemia in Coronavirus Disease 2019: A Case Report.
Topics: Acute Kidney Injury; Aged; Antibodies, Monoclonal, Humanized; Antioxidants; Ascorbic Acid; Betacoron | 2020 |
Baricitinib improves respiratory function in patients treated with corticosteroids for SARS-CoV-2 pneumonia: an observational cohort study.
Topics: Aged; Antiviral Agents; Azetidines; Cohort Studies; COVID-19; COVID-19 Drug Treatment; Drug Combinat | 2021 |
Continuous positive airway pressure in COVID-19 patients with moderate-to-severe respiratory failure.
Topics: Adult; Aged; Aged, 80 and over; Air Filters; Algorithms; Antibodies, Monoclonal, Humanized; Antirheu | 2021 |
Effectiveness of lopinavir/ritonavir on COVID-19-related pneumonia in a child with COVID-19-associated Kawasaki disease.
Topics: Ampicillin; Anti-Bacterial Agents; Anticoagulants; Antiviral Agents; Azithromycin; Child; COVID-19; | 2021 |
Acute pulmonary embolism in a child with ANCA-negative Idiopathic Pulmonary Capillaritis.
Topics: Acute Disease; Antibodies, Antineutrophil Cytoplasmic; Capillaries; Chest Pain; Child; Female; Hemor | 2019 |