Page last updated: 2024-10-28

hydroxychloroquine and Hypotension

hydroxychloroquine has been researched along with Hypotension in 9 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.

Research Excerpts

ExcerptRelevanceReference
" Treatment consisted of the rapid administration of intravenous diazepam, after which the hypotension recovered rapidly even though no vasoactive medication was given."3.74[Serious intoxication with hydroxychloroquine, with haemodynamic instability: a case report supporting treatment with diazepam]. ( Ligtenberg, JJ; Meertens, JH; Monteban-Kooistra, WE; Olgers, TJ; Tulleken, JE; Zijlstra, JG, 2008)
"Hydroxychloroquine poisoning has rarely been reported in the literature, with only 18 cases being found on searching the literature."2.44Hydroxychloroquine overdose: case report and recommendations for management. ( Graham, CA; Ling Ngan Wong, A; Tsz Fung Cheung, I, 2008)
"Quick treatment of hypotension, gastric decontamination, continuous long-term cardiac monitoring, and treatment of arrhythmias are the cornerstones of hydroxychloroquine overdose management."1.32Massive hydroxychloroquine overdose. ( Aksay, E; Atilla, R; Demir, OF; Yanturali, S, 2004)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's1 (11.11)18.2507
2000's5 (55.56)29.6817
2010's1 (11.11)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Pejčić, AV1
Ten Broeke, R1
Mestrom, E1
Woo, L1
Kreeftenberg, H1
ARORA, RB1
LAL, A1
Yanturali, S2
Aksay, E1
Demir, OF1
Atilla, R1
Ling Ngan Wong, A1
Tsz Fung Cheung, I1
Graham, CA1
Olgers, TJ1
Tulleken, JE1
Monteban-Kooistra, WE1
Ligtenberg, JJ1
Meertens, JH1
Zijlstra, JG1
Marquardt, K1
Albertson, TE1
de Jong-Straková, Z1
Blaauw, AA1
van der Linden, SJ1
Ferwerda, J1

Reviews

2 reviews available for hydroxychloroquine and Hypotension

ArticleYear
Acute Hydroxychloroquine Overdose: A Review of Published Pediatric Cases With Confirmed Hydroxychloroquine Exposure.
    Pediatric emergency care, 2022, Apr-01, Volume: 38, Issue:4

    Topics: Adolescent; Child; Child, Preschool; Drug Overdose; Female; Humans; Hydroxychloroquine; Hypotension;

2022
Hydroxychloroquine overdose: case report and recommendations for management.
    European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 2008, Volume: 15, Issue:1

    Topics: Alcohol Drinking; Coma; Drug Overdose; Epinephrine; Glasgow Coma Scale; Heart Rate; Humans; Hydroxyc

2008

Other Studies

7 other studies available for hydroxychloroquine and Hypotension

ArticleYear
Early treatment with intravenous lipid emulsion in a potentially lethal hydroxychloroquine intoxication.
    The Netherlands journal of medicine, 2016, Volume: 74, Issue:5

    Topics: Adult; Arrhythmias, Cardiac; Chromatography, Liquid; Drug Overdose; Electrocardiography; Fat Emulsio

2016
ANTIMALARIAL DRUGS ON THE AUTOMATICITY OF SINO-AURICULAR AND ATRIO-VENTRICULAR NODES.
    The Indian journal of medical research, 1963, Volume: 51

    Topics: Administration, Intravenous; Amodiaquine; Animals; Anti-Arrhythmia Agents; Antimalarials; Atrioventr

1963
Massive hydroxychloroquine overdose.
    Acta anaesthesiologica Scandinavica, 2004, Volume: 48, Issue:3

    Topics: Adolescent; Antirheumatic Agents; Charcoal; Drug Overdose; Electric Countershock; Female; Gastric La

2004
Diazepam for treatment of massive chloroquine intoxication.
    Resuscitation, 2004, Volume: 63, Issue:3

    Topics: Arrhythmias, Cardiac; Cardiovascular Agents; Diazepam; Drug Overdose; Female; Humans; Hydroxychloroq

2004
[Serious intoxication with hydroxychloroquine, with haemodynamic instability: a case report supporting treatment with diazepam].
    Nederlands tijdschrift voor geneeskunde, 2008, Mar-01, Volume: 152, Issue:9

    Topics: Adult; Diazepam; Drug Overdose; Female; Humans; Hydroxychloroquine; Hypotension; Treatment Outcome

2008
Treatment of hydroxychloroquine overdose.
    The American journal of emergency medicine, 2001, Volume: 19, Issue:5

    Topics: Adolescent; Adrenergic Agonists; Antirheumatic Agents; Cardiotonic Agents; Charcoal; Diazepam; Dopam

2001
[A patient with acute hydroxychloroquine poisoning; recommendation for treatment].
    Nederlands tijdschrift voor geneeskunde, 1990, Dec-15, Volume: 134, Issue:50

    Topics: Adult; Bradycardia; Critical Care; Gastric Lavage; Humans; Hydroxychloroquine; Hypotension; Male; Re

1990