hydroxychloroquine has been researched along with Hypokalemia in 16 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Hypokalemia: Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Toxic effects of hydroxychloroquine, like chloroquine, include membrane stabilization and hypokalemia, which is correlated with the severity of the overdose." | 7.73 | [Acute hydroxychloroquine poisoning. The danger of rapid or excessive correction of initial hypokalemia]. ( Baud, F; Deye, N; Guerrier, G; Mégarbane, B; Résière, D; Sonneville, R, 2005) |
| "Hydroxychloroquine poisoning has rarely been reported in the literature, with only 18 cases being found on searching the literature." | 2.44 | Hydroxychloroquine overdose: case report and recommendations for management. ( Graham, CA; Ling Ngan Wong, A; Tsz Fung Cheung, I, 2008) |
| "Investigations revealed distal renal tubular acidosis with severe metabolic bone disease as an extra-glandular manifestation of primary SS." | 1.56 | Primary Sjogren's syndrome manifesting with distal renal tubular acidosis and severe metabolic bone disease. ( Bhandari, S; Jain, G; Kalra, S; Vasnik, G, 2020) |
| "A ventricular fibrillation was treated with external cardiac massage." | 1.34 | [Treatment of hydroxychloroquine poisoning with extracorporeal circulation]. ( Blin, D; Derderian, F; Durand, M; Gonthier, YT; Mongenot, F, 2007) |
| "Quick treatment of hypotension, gastric decontamination, continuous long-term cardiac monitoring, and treatment of arrhythmias are the cornerstones of hydroxychloroquine overdose management." | 1.32 | Massive hydroxychloroquine overdose. ( Aksay, E; Atilla, R; Demir, OF; Yanturali, S, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (43.75) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 6 (37.50) | 2.80 |
| Authors | Studies |
|---|---|
| TeBay, C | 1 |
| McArthur, JR | 1 |
| Mangala, M | 1 |
| Kerr, N | 1 |
| Heitmann, S | 1 |
| Perry, MD | 1 |
| Windley, MJ | 1 |
| Vandenberg, JI | 1 |
| Hill, AP | 1 |
| Srihari, P | 1 |
| Minns, AB | 1 |
| Gao, HT | 1 |
| Kreshak, AA | 1 |
| Habibzadeh, P | 1 |
| Moghadami, M | 1 |
| Lankarani, KB | 1 |
| Jain, G | 1 |
| Kalra, S | 1 |
| Vasnik, G | 1 |
| Bhandari, S | 1 |
| Gautret, P | 2 |
| Honoré, S | 2 |
| Lagier, JC | 2 |
| Raoult, D | 2 |
| Hoang, VT | 1 |
| Ten Broeke, R | 1 |
| Mestrom, E | 1 |
| Woo, L | 1 |
| Kreeftenberg, H | 1 |
| Merino Argumánez, C | 1 |
| Sáez de La Fuente, I | 1 |
| Molina Collado, Z | 1 |
| Suárez Pita, D | 1 |
| Mestre Gómez, B | 1 |
| Sanchez Izquierdo, JA | 1 |
| Wu, TJ | 1 |
| Yan, MT | 1 |
| Chau, T | 1 |
| Lin, SH | 1 |
| Logan, JL | 1 |
| Ahmed, J | 1 |
| Yanturali, S | 2 |
| Aksay, E | 1 |
| Demir, OF | 1 |
| Atilla, R | 1 |
| Mégarbane, B | 1 |
| Résière, D | 1 |
| Sonneville, R | 1 |
| Guerrier, G | 1 |
| Deye, N | 1 |
| Baud, F | 1 |
| Mongenot, F | 1 |
| Gonthier, YT | 1 |
| Derderian, F | 1 |
| Durand, M | 1 |
| Blin, D | 1 |
| Ling Ngan Wong, A | 1 |
| Tsz Fung Cheung, I | 1 |
| Graham, CA | 1 |
| Marquardt, K | 1 |
| Albertson, TE | 1 |
2 reviews available for hydroxychloroquine and Hypokalemia
| Article | Year |
|---|---|
Hydroxychloroquine, a potentially lethal drug.
Topics: Adult; Anisocoria; Coma; Connective Tissue Diseases; Emergencies; Female; Heart Arrest; Humans; Hydr | 2017 |
Hydroxychloroquine overdose: case report and recommendations for management.
Topics: Alcohol Drinking; Coma; Drug Overdose; Epinephrine; Glasgow Coma Scale; Heart Rate; Humans; Hydroxyc | 2008 |
14 other studies available for hydroxychloroquine and Hypokalemia
| Article | Year |
|---|---|
Pathophysiological metabolic changes associated with disease modify the proarrhythmic risk profile of drugs with potential to prolong repolarisation.
Topics: Acidosis; Azithromycin; Chloroquine; COVID-19 Drug Treatment; Female; Humans; Hydroxychloroquine; Hy | 2022 |
Massive Nonfatal Hydroxychloroquine Ingestion in a Pediatric Patient.
Topics: Adolescent; Child; Diazepam; Drug Overdose; Eating; Epinephrine; Female; Humans; Hydroxychloroquine; | 2022 |
The effect of potential therapeutic agents on QT interval in patients with COVID-19 Infection: The importance of close monitoring and correction of electrolytes.
Topics: Antiviral Agents; Betacoronavirus; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug C | 2020 |
Primary Sjogren's syndrome manifesting with distal renal tubular acidosis and severe metabolic bone disease.
Topics: Absorptiometry, Photon; Acidosis, Renal Tubular; Adolescent; Antirheumatic Agents; Arthralgia; Bone | 2020 |
Safety profile of hydroxychloroquine and azithromycin combined treatment in COVID-19 patients.
Topics: Anti-Bacterial Agents; Antimalarials; Antiviral Agents; Azithromycin; Clinical Trials as Topic; COVI | 2021 |
Clinical efficacy and safety profile of hydroxychloroquine and azithromycin against COVID-19.
Topics: Anti-Bacterial Agents; Antimalarials; Antiviral Agents; Azithromycin; Clinical Trials as Topic; COVI | 2021 |
Early treatment with intravenous lipid emulsion in a potentially lethal hydroxychloroquine intoxication.
Topics: Adult; Arrhythmias, Cardiac; Chromatography, Liquid; Drug Overdose; Electrocardiography; Fat Emulsio | 2016 |
Hypokalemic paralysis in a girl with dental and renal calculi. Distal renal tubular acidosis (RTA).
Topics: Acidosis, Renal Tubular; Adolescent; Child; Child, Preschool; Dental Calculus; Dental Restoration, P | 2013 |
Critical hypokalemic renal tubular acidosis due to Sjögren's syndrome: association with the purported immune stimulant echinacea.
Topics: Acidosis, Renal Tubular; Adjuvants, Immunologic; Adult; Antirheumatic Agents; Citrates; Echinacea; E | 2003 |
Massive hydroxychloroquine overdose.
Topics: Adolescent; Antirheumatic Agents; Charcoal; Drug Overdose; Electric Countershock; Female; Gastric La | 2004 |
Diazepam for treatment of massive chloroquine intoxication.
Topics: Arrhythmias, Cardiac; Cardiovascular Agents; Diazepam; Drug Overdose; Female; Humans; Hydroxychloroq | 2004 |
[Acute hydroxychloroquine poisoning. The danger of rapid or excessive correction of initial hypokalemia].
Topics: Adult; Antimalarials; Female; Humans; Hydroxychloroquine; Hypokalemia; Poisoning; Risk Factors; Suic | 2005 |
[Treatment of hydroxychloroquine poisoning with extracorporeal circulation].
Topics: Adult; Antidotes; Bromazepam; Charcoal; Coma; Combined Modality Therapy; Diazepam; Drug Overdose; Ep | 2007 |
Treatment of hydroxychloroquine overdose.
Topics: Adolescent; Adrenergic Agonists; Antirheumatic Agents; Cardiotonic Agents; Charcoal; Diazepam; Dopam | 2001 |