Page last updated: 2024-10-28

hydroxychloroquine and Hypertension, Pulmonary

hydroxychloroquine has been researched along with Hypertension, Pulmonary in 6 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Hypertension, Pulmonary: Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.

Research Excerpts

ExcerptRelevanceReference
" Two years prior to admission to our hospital, she had been diagnosed with rheumatoid arthritis and treated with hydroxychloroquine (HCQ) with a cumulative dose of 164 g."7.78Hydroxychloroquine-induced cardiomyopathy that presented as pulmonary hypertension: a newly noted complication. ( Bae, SM; Chin, JY; Ihm, SM; Jung, HO; Kim, JJ; Kim, TS; Lee, KY; Park, SH; Youn, HJ, 2012)
" For inflammatory arthritis, 79% of experts agreed (first- through fourth-line treatments were MTX, low-dose glucocorticoids, hydroxychloroquine, and rituximab or tocilizumab, respectively)."3.88Treatment Algorithms for Systemic Sclerosis According to Experts. ( Fernández-Codina, A; Pope, JE; Walker, KM, 2018)
" Two years prior to admission to our hospital, she had been diagnosed with rheumatoid arthritis and treated with hydroxychloroquine (HCQ) with a cumulative dose of 164 g."3.78Hydroxychloroquine-induced cardiomyopathy that presented as pulmonary hypertension: a newly noted complication. ( Bae, SM; Chin, JY; Ihm, SM; Jung, HO; Kim, JJ; Kim, TS; Lee, KY; Park, SH; Youn, HJ, 2012)
"A rare case of childhood pulmonary haemosiderosis with juvenile idiopathic arthritis is discussed, with particular reference to treatment with hydroxychloroquine and sildenafil for pulmonary hypertension which occurs secondary to this disease."3.74Pulmonary haemosiderosis with juvenile idiopathic arthritis in a Malaysian child. ( Noor, AS; Quah, BS; Rasool, AH; Roberton, D; Wong, AR, 2007)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's3 (50.00)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Fanouriakis, A1
Tziolos, N1
Bertsias, G1
Boumpas, DT1
Kaur, H1
Sarma, P1
Bhattacharyya, A1
Prajapat, M1
Kumar, S1
Prakash, A1
Medhi, B1
Fernández-Codina, A1
Walker, KM1
Pope, JE1
Lochouarn, M1
Lagier, JC1
Raoult, D1
Pulcini, C1
Wong, AR1
Noor, AS1
Rasool, AH1
Quah, BS1
Roberton, D1
Bae, SM1
Jung, HO1
Ihm, SM1
Kim, JJ1
Chin, JY1
Kim, TS1
Park, SH1
Youn, HJ1
Lee, KY1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Optimization of Glucocorticoid Taper Strategies for Maintenance Therapy of Systemic Lupus Erythematosus Associated Immune Thrombocytopenia (SLE-ITP)[NCT05506033]120 participants (Anticipated)Interventional2022-08-15Enrolling by invitation
The Effectiveness of ECP in Diffuse Cutaneous Systemic Sclerosis[NCT04986605]Phase 215 participants (Anticipated)Interventional2023-12-01Not yet recruiting
Pragmatic Clinical Trials in Scleroderma[NCT03610217]400 participants (Anticipated)Interventional2018-10-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for hydroxychloroquine and Hypertension, Pulmonary

ArticleYear
Update οn the diagnosis and management of systemic lupus erythematosus.
    Annals of the rheumatic diseases, 2021, Volume: 80, Issue:1

    Topics: Anemia, Hemolytic, Autoimmune; Antibodies, Monoclonal, Humanized; Autoantibodies; Azathioprine; Calc

2021

Other Studies

5 other studies available for hydroxychloroquine and Hypertension, Pulmonary

ArticleYear
Folic acid as placebo in controlled clinical trials of hydroxychloroquine prophylaxis in COVID-19: Is it scientifically justifiable?
    Medical hypotheses, 2021, Volume: 149

    Topics: Angiotensin-Converting Enzyme 2; COVID-19; COVID-19 Drug Treatment; Folic Acid; Humans; Hydroxychlor

2021
Treatment Algorithms for Systemic Sclerosis According to Experts.
    Arthritis & rheumatology (Hoboken, N.J.), 2018, Volume: 70, Issue:11

    Topics: Algorithms; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antibodies,

2018
Treatment Algorithms for Systemic Sclerosis According to Experts.
    Arthritis & rheumatology (Hoboken, N.J.), 2018, Volume: 70, Issue:11

    Topics: Algorithms; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antibodies,

2018
Treatment Algorithms for Systemic Sclerosis According to Experts.
    Arthritis & rheumatology (Hoboken, N.J.), 2018, Volume: 70, Issue:11

    Topics: Algorithms; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antibodies,

2018
Treatment Algorithms for Systemic Sclerosis According to Experts.
    Arthritis & rheumatology (Hoboken, N.J.), 2018, Volume: 70, Issue:11

    Topics: Algorithms; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antibodies,

2018
A case of Whipple's disease evolving over 30 years.
    Medecine et maladies infectieuses, 2014, Volume: 44, Issue:7

    Topics: Anti-Bacterial Agents; Antibodies, Bacterial; Aortic Valve Insufficiency; Biopsy; Disease Progressio

2014
Pulmonary haemosiderosis with juvenile idiopathic arthritis in a Malaysian child.
    The Medical journal of Malaysia, 2007, Volume: 62, Issue:4

    Topics: Adolescent; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Juvenile; Female; Hemosideros

2007
Hydroxychloroquine-induced cardiomyopathy that presented as pulmonary hypertension: a newly noted complication.
    Cardiology, 2012, Volume: 123, Issue:3

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cardiac Catheterization; Cardiomyopathies; Female; Huma

2012