hydroxychloroquine has been researched along with Heart Valve Diseases in 6 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Heart Valve Diseases: Pathological conditions involving any of the various HEART VALVES and the associated structures (PAPILLARY MUSCLES and CHORDAE TENDINEAE).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Coxiella burnetii causes acute and chronic Q fever." | 1.31 | Risks factors and prevention of Q fever endocarditis. ( Carrieri, MP; Fenollar, F; Fournier, PE; Habib, G; Messana, T; Raoult, D, 2001) |
| "Q fever is a zoonosis caused by Coxiella burnetii." | 1.30 | Q fever tricuspid valve endocarditis. ( Brouqui, P; Casasoprana, A; Hvass, U; Lupoglazoff, JM; Magnier, S, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Fanouriakis, A | 1 |
| Tziolos, N | 1 |
| Bertsias, G | 1 |
| Boumpas, DT | 1 |
| Montejo, M | 1 |
| Goikoetxea, J | 1 |
| Mularoni, A | 1 |
| Blanco, MJ | 1 |
| Gaafar, A | 1 |
| Boado, MV | 1 |
| Marín, M | 1 |
| Aramendi, JI | 1 |
| Emonet, S | 1 |
| Wuillemin, T | 1 |
| Harbarth, S | 1 |
| Wassilew, N | 1 |
| Cikirikcioglu, M | 1 |
| Schrenzel, J | 1 |
| Lagier, JC | 1 |
| Raoult, D | 2 |
| van Delden, C | 1 |
| Lupoglazoff, JM | 1 |
| Brouqui, P | 1 |
| Magnier, S | 1 |
| Hvass, U | 1 |
| Casasoprana, A | 1 |
| Fenollar, F | 1 |
| Fournier, PE | 1 |
| Carrieri, MP | 1 |
| Habib, G | 1 |
| Messana, T | 1 |
| Turpie, AG | 1 |
| Hirsh, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Optimization of Glucocorticoid Taper Strategies for Maintenance Therapy of Systemic Lupus Erythematosus Associated Immune Thrombocytopenia (SLE-ITP)[NCT05506033] | 120 participants (Anticipated) | Interventional | 2022-08-15 | Enrolling by invitation | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for hydroxychloroquine and Heart Valve Diseases
| Article | Year |
|---|---|
Update οn the diagnosis and management of systemic lupus erythematosus.
Topics: Anemia, Hemolytic, Autoimmune; Antibodies, Monoclonal, Humanized; Autoantibodies; Azathioprine; Calc | 2021 |
Platelet suppressive therapy.
Topics: Arteriovenous Shunt, Surgical; Aspirin; Blood Platelets; Cerebrovascular Disorders; Clofibrate; Coro | 1978 |
4 other studies available for hydroxychloroquine and Heart Valve Diseases
| Article | Year |
|---|---|
[Tropheryma wipplei endocarditis: a report of 3 cases].
Topics: Actinomycetales Infections; Anti-Bacterial Agents; Anticoagulants; Doxycycline; Drug Therapy, Combin | 2013 |
Relapse of Tropheryma whipplei endocarditis treated by trimethoprim/sulfamethoxazole, cured by hydroxychloroquine plus doxycycline.
Topics: Anti-Bacterial Agents; Aortic Valve; Ceftriaxone; Doxycycline; Drug Therapy, Combination; Endocardit | 2015 |
Q fever tricuspid valve endocarditis.
Topics: Anti-Bacterial Agents; Child; Doxycycline; Drug Therapy, Combination; Endocarditis, Bacterial; Femal | 1997 |
Risks factors and prevention of Q fever endocarditis.
Topics: Aged; Anti-Infective Agents; Doxycycline; Endocarditis, Bacterial; Female; Heart Valve Diseases; Hum | 2001 |