hydroxychloroquine has been researched along with Hearing Loss in 3 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Hearing Loss: A general term for the complete or partial loss of the ability to hear from one or both ears.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Several cases of hearing loss induced by hydroxychloroquine have been reported in the literature but the role of hydroxychloroquine still remains debated." | 7.85 | [Hydroxychloroquine-induced hearing loss: First case of positive rechallenge and analysis of the French pharmacovigilance database]. ( Auffret, M; Bondon-Guitton, E; Chatelet, JN; Combret, S; Gautier, S; Lambert, M, 2017) |
| " The suggested dose of chloroquine for COVID-19 infection is considerably higher than the usual dosage for malaria treatment; therefore, it is plausible that the ototoxic effects will be greater." | 6.66 | Clinical Implications of Chloroquine and Hydroxychloroquine Ototoxicity for COVID-19 Treatment: A Mini-Review. ( Baguley, DM; Kasbekar, AV; Prayuenyong, P, 2020) |
| "Several cases of hearing loss induced by hydroxychloroquine have been reported in the literature but the role of hydroxychloroquine still remains debated." | 3.85 | [Hydroxychloroquine-induced hearing loss: First case of positive rechallenge and analysis of the French pharmacovigilance database]. ( Auffret, M; Bondon-Guitton, E; Chatelet, JN; Combret, S; Gautier, S; Lambert, M, 2017) |
| " The suggested dose of chloroquine for COVID-19 infection is considerably higher than the usual dosage for malaria treatment; therefore, it is plausible that the ototoxic effects will be greater." | 2.66 | Clinical Implications of Chloroquine and Hydroxychloroquine Ototoxicity for COVID-19 Treatment: A Mini-Review. ( Baguley, DM; Kasbekar, AV; Prayuenyong, P, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Prayuenyong, P | 1 |
| Kasbekar, AV | 1 |
| Baguley, DM | 1 |
| Gonçalves, LF | 1 |
| Patatt, FSA | 1 |
| de Paiva, KM | 1 |
| Haas, P | 1 |
| Chatelet, JN | 1 |
| Auffret, M | 1 |
| Combret, S | 1 |
| Bondon-Guitton, E | 1 |
| Lambert, M | 1 |
| Gautier, S | 1 |
2 reviews available for hydroxychloroquine and Hearing Loss
| Article | Year |
|---|---|
Clinical Implications of Chloroquine and Hydroxychloroquine Ototoxicity for COVID-19 Treatment: A Mini-Review.
Topics: Antimalarials; Antiviral Agents; Chloroquine; COVID-19 Drug Treatment; Emergencies; Hearing Loss; Hu | 2020 |
Ototoxic effects of hydroxychloroquine.
Topics: Hearing Loss; Humans; Hydroxychloroquine; Ototoxicity | 2021 |
1 other study available for hydroxychloroquine and Hearing Loss
| Article | Year |
|---|---|
[Hydroxychloroquine-induced hearing loss: First case of positive rechallenge and analysis of the French pharmacovigilance database].
Topics: Adult; Antirheumatic Agents; Databases, Factual; Female; France; Hearing Loss; Humans; Hydroxychloro | 2017 |