Page last updated: 2024-10-28

hydroxychloroquine and Granulomatous Disease, Chronic

hydroxychloroquine has been researched along with Granulomatous Disease, Chronic in 3 studies

Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.

Granulomatous Disease, Chronic: A defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granuloma formation. When chronic granulomatous disease is caused by mutations in the CYBB gene, the condition is inherited in an X-linked recessive pattern. When chronic granulomatous disease is caused by CYBA, NCF1, NCF2, or NCF4 gene mutations, the condition is inherited in an autosomal recessive pattern.

Research Excerpts

ExcerptRelevanceReference
"Hydroxychloroquine appears to be a safe and effective alternative treatment of granulomas in CGD patients."1.35Efficiency of hydroxychloroquine in the treatment of granulomatous complications in chronic granulomatous disease. ( Aouba, A; Arlet, JB; Blanche, S; Cellier, C; Damotte, D; Fischer, A; Hermine, O; Suarez, F; Valeyre, D, 2008)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wolpowitz, D1
Wise, EM1
Gerbing, EK1
Metze, D1
Luger, TA1
Ständer, S1
Arlet, JB1
Aouba, A1
Suarez, F1
Blanche, S1
Valeyre, D1
Fischer, A1
Damotte, D1
Cellier, C1
Hermine, O1

Other Studies

3 other studies available for hydroxychloroquine and Granulomatous Disease, Chronic

ArticleYear
Lupus-like rash of chronic granulomatous disease effectively treated with hydroxychloroquine.
    Cutis, 2015, Volume: 95, Issue:5

    Topics: Adult; Diagnosis, Differential; Enzyme Inhibitors; Facial Dermatoses; Granulomatous Disease, Chronic

2015
[Interstitial granulomatous dermatitis without arthritis: successful therapy with hydroxychloroquine].
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2003, Volume: 1, Issue:2

    Topics: Arthritis; Dermatitis; Dermatologic Agents; Female; Granulomatous Disease, Chronic; Humans; Hydroxyc

2003
Efficiency of hydroxychloroquine in the treatment of granulomatous complications in chronic granulomatous disease.
    European journal of gastroenterology & hepatology, 2008, Volume: 20, Issue:2

    Topics: Adult; Gastrointestinal Agents; Granulomatous Disease, Chronic; Humans; Hydroxychloroquine; Male; St

2008