hydroxychloroquine has been researched along with Granulomatous Disease, Chronic in 3 studies
Hydroxychloroquine: A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)
hydroxychloroquine : An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Granulomatous Disease, Chronic: A defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granuloma formation. When chronic granulomatous disease is caused by mutations in the CYBB gene, the condition is inherited in an X-linked recessive pattern. When chronic granulomatous disease is caused by CYBA, NCF1, NCF2, or NCF4 gene mutations, the condition is inherited in an autosomal recessive pattern.
Excerpt | Relevance | Reference |
---|---|---|
"Hydroxychloroquine appears to be a safe and effective alternative treatment of granulomas in CGD patients." | 1.35 | Efficiency of hydroxychloroquine in the treatment of granulomatous complications in chronic granulomatous disease. ( Aouba, A; Arlet, JB; Blanche, S; Cellier, C; Damotte, D; Fischer, A; Hermine, O; Suarez, F; Valeyre, D, 2008) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (66.67) | 29.6817 |
2010's | 1 (33.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Wolpowitz, D | 1 |
Wise, EM | 1 |
Gerbing, EK | 1 |
Metze, D | 1 |
Luger, TA | 1 |
Ständer, S | 1 |
Arlet, JB | 1 |
Aouba, A | 1 |
Suarez, F | 1 |
Blanche, S | 1 |
Valeyre, D | 1 |
Fischer, A | 1 |
Damotte, D | 1 |
Cellier, C | 1 |
Hermine, O | 1 |
3 other studies available for hydroxychloroquine and Granulomatous Disease, Chronic
Article | Year |
---|---|
Lupus-like rash of chronic granulomatous disease effectively treated with hydroxychloroquine.
Topics: Adult; Diagnosis, Differential; Enzyme Inhibitors; Facial Dermatoses; Granulomatous Disease, Chronic | 2015 |
[Interstitial granulomatous dermatitis without arthritis: successful therapy with hydroxychloroquine].
Topics: Arthritis; Dermatitis; Dermatologic Agents; Female; Granulomatous Disease, Chronic; Humans; Hydroxyc | 2003 |
Efficiency of hydroxychloroquine in the treatment of granulomatous complications in chronic granulomatous disease.
Topics: Adult; Gastrointestinal Agents; Granulomatous Disease, Chronic; Humans; Hydroxychloroquine; Male; St | 2008 |